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Ginger extractive, prepn. method and use thereof

A technology of ginger extract and medicine, applied in the field of ginger extract and preparation thereof, can solve the problems of no further breakthrough, inability to solve the problem of atherosclerosis, etc., and achieves low cost of raw materials, improvement of blood rheology, myocardial relaxation and contraction The effect of performance improvement

Inactive Publication Date: 2005-11-09
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are hundreds of traditional Chinese medicines used to treat cardiovascular diseases, no further breakthroughs have been made because they cannot solve the problem of atherosclerosis pharmacologically.

Method used

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  • Ginger extractive, prepn. method and use thereof
  • Ginger extractive, prepn. method and use thereof
  • Ginger extractive, prepn. method and use thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0038] The preparation of the ginger extract of the present invention and its pharmacological activity experiments are illustrated in the following examples. It should not be construed as limiting the claims of the present invention in any sense.

[0039] Preparation of ginger extract

Embodiment 1

[0041] Weigh 10kg of raw ginger that has been pre-dried and crushed to a particle size below 1mm, put it into the extraction kettle, and feed it with supercritical CO 2 The fluid is extracted at 25MPa and 35°C for 1 hour; the extract enters the separation tank and is separated at 10MPa and 50°C for 1 hour to obtain ginger supercritical CO 2 Extract.

Embodiment 2

[0043] Put dried 10kg of raw ginger crushed to a particle size below 1mm into the extraction kettle, and pass through supercritical CO 2 The fluid is extracted at 20MPa and 40°C for 3 hours; the extract enters the separation tank and separated at 5MPa and 60°C for 2 hours to obtain ginger extract.

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Abstract

A ginger extract mainly containing the volatile oil of ginger and gingerol for preparing medicines to treat heart failure, myocardial ischemia, atherosclerosis, etc is prepared from the dried ginger through pulverizing, supercritical CO2 fluid extracting and separation.

Description

technical field [0001] The present invention relates to ginger extract and preparation method thereof using the rhizome of ginger (Zingiber offfficinale Rosc) as raw material; [0002] The invention also relates to the application of the ginger extract in the preparation of medicines for treating cardiovascular diseases. Background technique [0003] Cardiovascular disease is one of the major diseases that threaten human beings. Although the mortality rate of cardiovascular disease has declined to varying degrees in most countries except Eastern European countries in the past 30 years, it is still the first cause of death among men over 45 years old in most countries. The cause of death is the second cause of death after tumors in women, which seriously affects the life expectancy and quality of life of human beings. In China, with the improvement of living standards, the number of people suffering from cardiovascular disease continues to rise, and it is showing a younger t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 王宁生
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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