The invention discloses ginseng wine and a production technology thereof. Each 2500ml of the ginseng wine contains 25g of ginseng, 90g of wolfberry, 65g of manyflower solomonseal rhizome, 38g of cordyceps militaris, 60g of arillus longan and 2500ml of pure grain liquor. The ginseng wine is prepared through the processes of material selection, material washing, slicing, drying, extraction, sedimentation and fine filtration, and canning. The ginseng wine has the functions of improving human physique and disease resistance, nourishing liver and kidney, boosting essence and improving eyesight, supplementing heart and spleen, nourishing blood and soothing nerves, reducing blood pressure and blood sugar, delaying aging, and resisting and inhibiting cancers.