30 results about "Sodium edetate" patented technology

The invention relates to a composition of esomeprazole sodium freeze-dried powder for injection and a preparation method thereof. The composition is mainly used for treating stomach burning sensation caused by non-erosive gastroesophageal reflux disease, Gastrointestinal diseases such as erosive esophagitis. The main ingredients of the composition are esomeprazole sodium, sodium chloride, sodium hydroxide, and calcium sodium ethylenediamine tetraacetate. During the preparation process, low-temperature feeding, nitrogen flushing protection, and low-temperature sublimation and low-temperature analysis and drying are used to prepare the composition. craft. The freeze-dried powder compound prepared by this kind of prescription and preparation process has beautiful freeze-dried shape, stable product quality, less impurity content, good resolubility, reduced production cost, expanded production batch, convenient clinical medication, and can obtain good results. economic and social benefits.

The invention discloses a water-replenishing moisturizing essence with long-lasting moisturizing effects. The essence comprises the following components: hyaluronic acid, pentanediol, dipropylene glycol, butanediol, 1,3-propanediol, panthenol, glycerin, polysorbate 20, sodium edetate, octanediol, ethylhexylglycerin, phenoxyethanol and distilled water, wherein hyaluronic acid is a natural substancethroughout the human body, and plays an important role in tissue hydration, lubrication and cell functions; and panthenol has the potential to improve skin appearances including dryness, roughness, desquamation, pruritus and erythema, and in addition, moisturizing properties of panthenol improve the hydration of stratum corneum, reduce the loss of epidermal moisture, and maintain the skin's elasticity and softness. The water-replenishing moisturizing essence of the invention can keep cells moist for 24 h, is suitable for skin dryness, and can restore water to cells. The use of the product canmake cosmetics look better. At the same time, the product also has the anti-aging function, and can improve effects.

The invention discloses a lubricant for root canal treatment, which comprises sodium edetate, citric acid, carbamide peroxide, cetyltrimethylammonium bromide, sodium carboxymethylcellulose, glycerin and water. The lubricant of the present invention can soften the root canal wall, reduce preparation resistance, and is especially suitable for the preparation of large-tapered nickel-titanium instruments. By comparing the use of root canal lubricant (experimental group) and no use of root canal lubricant (control group) two groups of experiments Similarly, the results of clinical trials show that the use of root canal lubricants in the root canal preparation process, the detection rate of bacteria in the root canal was significantly lower than that of the group without lubricants, indicating that the use of lubricants in the root canal preparation process helps to eliminate the bacteria in the root canal. Bacteria, creating conditions conducive to the healing of clinical chronic apical periodontitis.

The invention discloses an alcohol-free fountain solution, which is characterized in that it is composed of the following raw materials in parts by weight: propylene glycol alginate 2-10, epoxy butyl stearate 1-5, glycine 1-3, arginine Acid 1‑3, Sodium Lauryl Sulfate 1‑8, Hydroxyethyl Urea 1‑5, Hydrogen Peroxide 0.5‑1, Tannin 1‑3, Vanillin 1‑2, Sodium EDTA1‑3 , silicone defoamer 0.2‑1, additives 5‑10, water 30‑50. The fountain solution of the invention does not need to add IPA or other alcohol additives during use, which not only reduces the cost, but also is gentle and harmless to the human body and the environment, and meets the requirements of energy saving, environmental protection and safety.

The invention discloses a method for preparing sodium ethylenediaminoethanesulfonate. The method comprises the following steps: taurine, nitromethane and formaldehyde occur Mannich reaction to generate N-(2-nitroethyl) taurine, and then N-(2-nitroethyl) taurine Sodium ethylenediaminoethanesulfonate can be obtained through alkali neutralization and hydrogenation reaction. The product selectivity is greater than 99%, and the product yield is greater than 97%. The process route has abundant sources of raw materials, is environmentally friendly, has high product selectivity and high product yield, and is suitable for industrial production.

The invention provides a kurarinone freeze-dry powder preparation and a preparation method thereof. The preparation method comprises the following steps: filtering the solution of three components - kurarinone, mannitol, disodium edetate or calcio-sodium edetate in an appropriate proportion, freezing and drying, and then obtaining the freeze-dry powder preparation. Compared with the prior product, the preparation has the advantages that the stability is obviously improved, the expiry date can be as long as 24 months, and the characters of the product are not changed obviously; compared with the prior art, the preparation method is more simplified, and the production cost is saved. The invention also provides a method for detecting the content of oxymatrine in the product of kurarinone freeze-dry powder preparation. By optimizing the mobile phase and the detection condition, a highly-effective liquid-phase chromatographic detection method with better differentiation and stronger specificity is established.

The present invention relates to an equipment cleaning agent suitable for use in petroleum and chemical industries, in particular to a ferrous sulfate dirt neutral complexing cleaning agent used for cleaning synthetic ammonia low-temperature methanol washing unit systems in petrochemical and coal chemical industries. Preparation of raw materials in the following parts by weight: 5 to 8 parts of sodium gluconate, 7 to 11 parts of sodium salicylate, 20 to 26 parts of ammonium diethylenetriaminepentaacetate, 20 to 26 parts of sodium edetate, 40 parts ~46 parts of acrylic acid-itaconic acid copolymer, 25~32 parts of polyepoxysodium succinate, 12~15 parts of sodium p-hydroxyphenylacetate, 3~7 parts of triethanolamine, 3~7 parts of hydrogen peroxide, 0.1~0.3 parts of ten Dialkyl sodium sulfate, 0.1-0.3 parts of polydimethylsilicone oil and 40-45 parts of water. It does not produce hydrogen sulfide gas when cleaning ferrous sulfide dirt, has no corrosion on equipment, has a strong ability to complex iron ions, has a fast removal speed, and has a descaling rate of more than 98%. It does not need to be neutralized and blunted after chemical cleaning. After chemical treatment, the equipment can be put into operation.

The invention discloses a method for improving the hard water resistance of magnesium aluminum silicate inorganic gel, which comprises the following steps: (1) adding a modifier to powdery magnesium aluminum silicate inorganic gel; the modifier is selected from One or more of sodium carbonate, sodium fluoride, sodium phosphate, sodium oxalate, sodium citrate and sodium edetate; (2) After fully stirring, heat up to 30~80°C while stirring, and keep for 5 ~20min; (3) Cool to room temperature to obtain the modified magnesium aluminum silicate product. The modified inorganic gel product prepared by the inventive method is made into a 1% standard hard water dispersion system, and the amount of clear water precipitation after standing still for 24 hours is significantly reduced, or even no clear water precipitation, indicating that it has excellent suspension performance in hard water systems , which solves the problem that the existing magnesium aluminum silicate inorganic gel cannot be applied in hard water.

The invention discloses a creatine kinase isozyme detection reagent. The reagent is composed of reagent R1 and reagent R2 at a ratio of 4:1 by volume, wherein reagent R1 is composed of imidazole buffer, glucose, nanoparticles, N-acetylcysteine, sodium edetate, Adenosine diphosphate, coenzyme Ⅰ, ribonucleotide, pyruvate decarboxylase, 6-phosphate glucose dehydrogenase, hexokinase, goat anti-human CK-M polyclonal antibody and trehalose, reagent R2 is composed of imidazole buffer, creatine phosphate, sodium dodecylbenzenesulfonate and preservatives. The reagent of the invention is a stable, accurate and strong anti-interference reagent for detecting creatine kinase isoenzymes, and has high clinical application value.

The invention belongs to the field of planting flowers in gardens, and in particular relates to a ceramsite flower nutrient cultivation substrate which simultaneously provides sufficient nutrients in the growth period of flowers and a preparation method thereof. The main body of the present invention is ceramsite, and ceramsite is immersed in nutrients, complexing substances and coating slow-release substances. The ceramsite is light clay ceramsite; the nutrient substance is sodium humate HA-Na; the complexing substance is at least Including one of disodium edetate EDTA‑2Na, sodium EDTA‑4Na and pentasodium diethyltriaminepentaacetate DTPA‑5Na; coating sustained-release substances include gluing agents and polymeric things. According to the present invention, the ceramsite has the characteristics of large specific surface area, loose and porous inside, and can accommodate a large amount of water and nutrient elements. The air in the internal pores of the ceramsite is extracted through a decompression and vacuum device, and then the nutrient solution is injected to make the nutrient solution adsorb on the ceramsite. The slow release inside the ceramsite makes the ceramsite support and nourish flowers at the same time.

The invention provides a compound enzyme preparation, which comprises the following components: papain 1-2.5×104U / liter, bromelain 1000-3000U / liter, proline endonuclease 0.1-10PPU / liter, benzene Sodium formate 0.1-1%, ascorbic acid 0.1-1%, sodium edetate 0.1-1%, glycerin 20-50%, solvent is deionized water. The compound enzyme preparation has good stability, long shelf life, long-lasting and obvious effect of eliminating cold turbidity, can greatly reduce the dosage of enzyme preparation, and has extremely high commercial and promotional value.

The invention provides an oily sludge dewatering agent and its preparation method and a dehydration method of oily sludge. The dehydrating agent includes methacrylamide, acryloyloxyethyltrimethylammonium chloride, formaldehyde, ethylenediamine, peroxide Ammonium sulfate, sodium bisulfite, sodium edetate, polyoxyethylene laureth (20), azobisisobutyronitrile, acrylic acid, and deionized water. The dehydrating agent has various good performances through the selection and synergy of specific components and a specific preparation method, can be used for dehydration treatment of oily sludge, and has good application value and promotion potential.

The invention relates to the technical field of pharmaceutical analysis, in particular to a method for measuring content of sodium calcium edetate in a medicine and more specifically relates to a method for measuring the content of the sodium calcium edetate in Cleviprex fat emulsion injection. According to the method, liquid chromatogram is used for detecting the sodium calcium edentate; before detection, pre-column derivatization is carried out on the sodium calcium edetate so that the sodium calcium edetate can be converted into sodium ion EDTA; then, spherical graphite carbon serves as filler of a chromatographic column, and a mixed solution of a ferric sulfate water solution and ethanediol serves as a mobile phase for detection, wherein the pH of the mixed solution is 1-2. When the method is adopted for detection, main peak trailing factors are optimal, the number of theoretical plates is large, the peak width is small, symmetry is good, and the content of the sodium calcium edetate in the medicine can be precisely measured.

The invention relates to a clindamycin hydrochloride injection which contains clindamycin hydrochloride, sodium chloride for injection, L-cysteine and sodium edetate, the mass ratio of clindamycin hydrochloride to sodium chloride for injection to L-cysteine to sodium edetate is 50: (1-5): (0.04-0.2): (0.01-0.1), and the stability of the clindamycin hydrochloride injection is remarkably improved; meanwhile, a proper freeze-drying protective agent is selected so that the preservation time of the injection can be properly prolonged.

The invention discloses a cleaning agent for a heating system, which specifically comprises: sodium edetate, thiourea, 5-chloro-2-methyl-4-isothiazoline-3-one, sodium nitrite , mercaptobenzothiazole, sodium dodecylbenzenesulfonate, hexamethylenetetramine, zinc sulfate, sodium borohydride, diethylenetriaminepentamethylenephosphonic acid, citric acid, potassium chromate, sodium alginate, The balance is water; the invention also discloses the preparation method of the cleaning agent. The use of this powerful cleaning agent can completely remove all kinds of rust spots, dirt and solidified substances attached to boilers and pipes, and a protective film can be formed on the surface of boilers and pipes after cleaning to reduce the scaling speed of boilers and pipes. The cleaning agent for heating and heating systems of the present invention has strong acidity, good water solubility, no toxicity to human body, no corrosion to boilers and pipelines, can significantly improve the thermal efficiency of boilers and pipelines, has simple preparation process, convenient operation, and safe and reliable use.

The invention discloses an atenolol injection, which is made of atenolol and pharmaceutically acceptable auxiliary materials, and the concentration is 0.45mg / mL-0.55mg / mL in terms of atenolol; the auxiliary materials include : Composite solvent composed of 1,2‑propylene glycol and water; buffer system composed of sodium dihydrogen phosphate and disodium hydrogen phosphate; sodium chloride as osmotic pressure regulator; sodium edetate as metal ion complexing agent. In the composite solvent, the volume fraction of 1,2-propylene glycol is 10%-35%. The invention also discloses a preparation method of the atenolol injection. The method of adding charcoal twice can achieve the purpose of adsorbing the pyrogen in the injection, and will not produce obvious adsorption to the main drug of the solution. The atenolol injection prepared by the invention has good stability and is safe and effective for clinical use.

The invention discloses a cutting fluid with antibacterial and antifungal effects, which is characterized in that it is made of the following raw materials in parts by weight: sodium edetate 2-3, triethanolamine 2.5-3.5, sodium diacetate 1-2 , garlic oil 3-4, 8-hydroxyquinoline 1-1.5, diethanolamine 3-4, salicylic acid 2-3, fatty alcohol polyoxyethylene ether 4-5, cyclohexyl hexaphosphate 3-5, Sodium petroleum sulfonate 3-5, borax 2-4, auxiliary agent 5-7, deionized water 200; the present invention adds 8-hydroxyquinoline and garlic oil with antibacterial and antifungal effects, and improves the cutting fluid that is easy to become smelly, The disadvantage of being difficult to preserve; adding additives enhances the anti-wear, dispersing, lubricating, and film-forming properties; the cutting fluid of the present invention contains a variety of surfactants, which has good permeability and cleaning properties, and has fast cooling speed, lubricity and Good anti-rust performance, suitable for all kinds of metal processing.