The invention discloses lady cream and a preparation method thereof. The lady cream is prepared from propylene glycol, ethylhexyl palmitate, petrolatum, mineral oil, titanium dioxide, heterogeneous cetane, glycerin, polyglycerol-2 oleate, PEG-30 dipolyhydroxystearate, camellia seed oil, egg yolk oil, microcrystalline wax, a glycyrrhiza glabra root extract, pearl powder, glutathione, simmondsia chinensis seed oil, phenoxyethanol, methyl hydroxybenzoate, propyl hydroxybenzoate, deuterium-containing water, palmitoyl pentapeptide-5, a pseudoginseng root extract, a common cnidium fruit extract, a radix salviae miltiorrhizae extract, collagen, hyaluronic acid, oligopeptide-1, oligopeptide-5, oligopeptide-2, glabridin, niacinamide and tranexamic acid. The lady cream integrates the functions of moisturizing, polypeptide repairing, and blood circulation activating, blood stasis removing and hot dryness and dampness clearing of various plant extracting solutions, and thus the functions and the effects of a whole system are significant.