The invention belongs to the technical field of textile printing and dyeing, and particularly relates to a processing technology of a high wash-and-wear warp and weft double-elastic fabric by adoptingspandex elastic yarns as warp yarns and purified cotton as weft yarns. Spandex elastic yarns are used as warp yarns, and weft yarns are made of purified cotton. The processing technology includes thefollowing steps: weaving, designing, singeing, desizing, scouring, oxygen bleaching, dry shaping, mercerizing, processing with liquid ammonia, whitening, wash and wear finishing, and softening. By adopting the processing technology, strength reduction of the fabric can be reduced, so that wash-and-wear performance of fabric appearance reaches 3.5 grades or above under the AATCC 124 method after water washing five times. During the finishing process, the fabric is naturally shrunk by a mechanical force, so that the elasticity of the fabric reaches 15% or above under the ASTM D3107-2011 method.The fabric is soft and comfortable to wear, and has high wash and wear performance, high resilience and the like.