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117results about How to "Gentle method" patented technology

Pre-irradiation polypropylene graft copolymer and preparation method thereof

InactiveCN102108112AAvoid chain scissionReduce lossesPolymer sciencePolypropylene
The application relates to a pre-irradiation polypropylene graft copolymer and a preparation method thereof. At present, the exploration of methods for improving surface property remains a research hotspot in the field of modification of polypropylene always. The method comprises the following steps: performing pre-irradiation on polypropylene resin after having constant weight at the temperature of 60 DEG C by using a 60 Co radiation source or a DD-1.2 / 1.0-800 type high-frequency high-pressure electron accelerator in air, keeping the dosage rate at 300Gy / min, keeping the dose at 3-50kGy, adding the pre-radiated polypropylene resin into solution containing N, N'-methylenebis acrylamide, auxiliary monomers and additives, keeping the using amount of the N, N'-methylenebis acrylamide to be 0.5-5% by weight of the weight of polypropylene, performing nitrogen filling and oxygen removal on mixed solution for 30 minutes, then heating to 50-75 DEG C for performing reaction for 6 hours under magnetic stirring, nitrogen production and reflux conditions, washing the polypropylene resin which is filtered out with ethanol-water twice, further extracting with ethanol-water solution for 24 hours, drying at the temperature of 60 DEG C and enabling the weight to be constant. The method is used for preparing the polypropylene graft copolymer.
Owner:TECHN PHYSICS INST HEILONGJIANG ACADOF SCI

Preparation of PCV2 ORF2 capsid protein virus-like particles derived from escherichia coli

The invention relates to porcine circovirus PCV2 ORF2 gene optimized by using escherichia coli expression codon and a preparation method of PCV2 ORF2 capsid protein virus-like particles derived from the escherichia coli.
Owner:SA BIOTECH (SUZHOU) PTE LTD

Preparation method of lithium difluorophosphate

The invention belongs to the technical field of chemical synthesis and in particular to a preparation method of lithium difluorophosphate. In the method, lithium difluorophosphate is obtained by reaction of lithium hexafluorophosphate with substrate. The preparation method comprises the following steps: 1) under the protection of protective gas, adding lithium hexafluorophosphate into an organic solvent; 2) heating the solution to a dissolving temperature to obtain solution, then dropwise adding tri(trimethylsilane)borate or tri(trimethylsilane)phosphate into the solution, and forming precipitates; and 3) heating the solution to a reaction temperature, stirring at the reaction temperature and reacting, and after the reaction is finished, sequentially filtering, washing and drying precipitates, so that pure lithium difluorophosphate is obtained. The preparation method provided by the invention can be carried out under relatively mild conditions and has relatively high yield of lithium difluorophosphate, and batch production can be carried out without requiring complex operation.
Owner:武汉海斯普林科技发展有限公司

Preparation method of supramolecular anti-cancer drug (dicycloplatin)

The invention provides a preparation method of a supramolecular anti-cancer drug (dicycloplatin). The preparation method comprises the following steps of: adding carboplatin and 1,1-cyclobutanedicarboxylic acid into water according to the mol ratio of 1:1, dissolving and uniformly mixing to obtain the mixed solution, and standing the mixed solution in a dark place at the temperature of more than 0 DEG C and less than or equal to 60 DEG C for 3-9 days, and concentrating under reduced pressure or freeze-drying so as to obtain dicycloplatin. The preparation method disclosed by the invention is moderate in condition and environment friendly; both the yield and the purity of dicycloplatin can be up to nearly 100%; the batch yield can reach 1000g; and thus, the preparation method is particularly applied to industrial production.
Owner:ZHUYUE TONGDA MEDICAL TECH DEV SUZHOU CO LTD

Method for preparing metal and dielectric composite grains of silicon dioxide coated by Nano silver

This invention discloses a method for preparing metal dielectric composite particles of nanoscale Ag / SiO2. The method comprises: hydrolyzing tetraethyl orthosilicate by NH3 catalysis to prepare SiO2 microspheres, preparing AgClO4 electrolyte solutions with different concentrations, adding the prepared SiO2 microspheres into the AgClO4 electrolyte solutions, ultrasonicating in an electrolytic tank for 10min, inserting two electrodes into the electrolytic tank, applying DC to electrolyze and obtain the product, centrifuging to separate the product, washing with deionized water and ethanol repeatedly, and drying at 30-50 deg.C. This invention utilizes sonoelectrochemical method to deposit Ag nanoparticles onto the surface of SiO2 microspheres. The Ag nanoparticles are uniformly distributed onto the surface of SiO2 colloid, and have excellent potential applications.
Owner:NANJING UNIV

Preparation method and application of nano mesoporous silica doped hydrogel drug controlled-release carrier material

The invention belongs to the field of drug controlled-release carrier materials, and in particular discloses a preparation method and an application of a nano mesoporous silica doped hydrogel drug controlled-release carrier material. With gelatin GE, sodium alginate SA and nano mesoporous silica MSN as raw materials, firstly, a GE-SA semi-interpenetrating composite gel, which contains the MSN, isprepared by virtue of a Ca2+ physical cross-linking method; and then, polymer electrolyte membrane modifying is conducted on the hydrogel by virtue of chitosan CS, so that a stable GE-SA-CS (MSN) composite gel is obtained. A controlled-release effect of the composite hydrogel material on drugs is investigated by taking BSA, MH and IDM as model drugs. The composite hydrogel system, on the basis ofthe effective utilization of a drug 'warehousing' effect of the nano mesoporous silica, can obviously improve the drug loading capacity and encapsulation efficiency of the BSA, MH and IDM, and the composite hydrogel system and remarkably enhance the controlled-release effects of the BSA and the IDM. The hydrogel is gentle in preparation conditions, simple and convenient in method, natural in materials and free from sharp reactions, and the hydrogel is a novel pH-sensitive composite hydrogel drug controlled-release system having a broad application prospect.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Preparation method of polydopamine/hyaluronic acid modified coating polylactic acid membrane

InactiveCN105801897AGood biocompatibility and biodegradabilityPromote cell adhesionFlexible coversWrappersMulti materialCell adhesion
The invention provides a preparation method of a polydopamine / hyaluronic acid modified coating polylactic acid membrane. The method comprises the following steps: with polylactic acid (PLA) as a base material, coating the PLA surface with a layer of polydopamine coating for modification to obtain PDA / PLA based on the characteristic that the dopamine (DA) can be adhered to the surfaces of multiple materials; and performing further surface modification on the modified PDA / PLA base material through using DA grafted hyaluronic acid (HA-DA) prepared in advance to obtain a HA-DA / PDA / PLA composite material. The composite material prepared by the method provided by the invention has good degradability, cell adhesion and biocompatibility, and has a broad application prospect in the fields such as bone repair and packaging.
Owner:JIANGNAN UNIV

Method of preparing compound osseous tissue renovating material interconsistency agent of polylactic acid/hydroxyapatite

The invention relates to a method for preparing an inclusive agent of a polylactic acid or hydroxyapatite composite bone tissue restoring material, which comprises the following steps: getting processed hydroxyapatite by refluxing hydroxyapatite in the alcohol solution with surface modifier as the coupler for 12-48 hours; dissolving polylactic acid macromole monomer with terminal ethenyl and the processed hydroxyapatite in the organic solvent with initiating agent; protecting with nitrogen; extracting after extracting and drying the reactor; separating and purifying no-grafted polylactic acid macromole monomer; extracting the remainder; drying; getting the inclusive agent. The inclusive agent has the wide application, the low cost, the simple method, the mild synthesis condition, the strong utility and the easy industry production, which provides the boundary interaction of the organic or inorganic phase in polylactic acid or hydroxyapatite composite bone tissue restoring material, and improves the ergology property of bone tissue restoring material.
Owner:JINAN UNIVERSITY

Modified polyamide reverse osmosis membrane with chemically grafted GO (graphene oxide) on surface and preparation method of modified polyamide reverse osmosis membrane

InactiveCN108176246AHydrophilicPoor separation performanceSemi-permeable membranesReverse osmosisPolyamide
The invention provides a modified polyamide reverse osmosis membrane with chemically grafted GO (graphene oxide) on the surface and a preparation method of the modified polyamide reverse osmosis membrane. The modified polyamide reverse osmosis membrane is prepared from 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride and N-hydroxysuccinimide by catalyzing an amidation reaction of carboxyl and amino, and chemical grafting of layered nano-material GO on a polyamide reverse osmosis membrane; the surface of a polyamide membrane and GO are rich in carboxyl, and layer upon layer connection of membrane surface carboxyl and GO carboxyl is realized by catalysis of a grafting reaction on the basis of a multi-amino substance as an intermediate linker. GO has good oxidation resistance, andthe content of N-H bonds in chlorine reactive groups is increased by the amidation reaction, so that chlorine resistance of the polyamide reverse osmosis membrane can be greatly improved, and the service life is prolonged. The modified polyamide reverse osmosis membrane has the advantages that the flux and the interception rate are basically unchanged, and the modified membrane has good chlorine resistance and can stably run.
Owner:QINGDAO UNIV OF SCI & TECH

Method for preparing solid (4R-cis)-6-formyl-2,2-dimethyl-1,3-dioxane-4-tert-butyl acetate

The invention discloses a method for preparing solid (4R-cis)-6-formyl-2,2-dimethyl-1,3-dioxane-4-tert-butyl acetate and belongs to the pharmaceutical and chemical field. The method includes the following steps that a compound III is dissolved in a mixed solvent of methanol and water, potassium carbonate is added for hydrolysis, potassium carbonate is filtered out and removed, methanol is removed through distillation, an organic solvent is added, and an organic solvent solution of a compound II is obtained after washing; secondly, TEMPO, potassium bromide and sodium bicarbonate are added, stirred, mixed and cooled, then a sodium hypochlorite solution is added dropwise, stirring reaction is carried out, after reaction, a sodium thiosulfate solution is quenched, washed, dried and condensed, and a crude product of a compound I is obtained; thirdly, an organic solvent is added, cooled and stirred after being heated and dissolved and is crystallized and filtered to obtain solid crystal of the compound I. The preparation method is safe, environmentally friendly, easy and convenient to operate, high in yield, high in purify and capable of facilitating large-scale production.
Owner:VALIANT CO LTD

Method for preparing epoxy fatty acid methyl ester

The invention relates to an improved method for preparing epoxy fatty acid methyl ester, which is characterized in that a solid catalyst or a sodium bisulfate solid catalyst obtained by mixing 30-90 parts of sodium bisulfate, 10-50 parts of ferric sulfate and 0-20 parts of calcium sulfate is adopted in an epoxidation reaction. By using the solid catalyst, when catalytic activity of the solid catalyst corresponds to that of sulfuric acid, the reaction condition is temperate; the production safety is good; the obtained product has high epoxy value which can reach more than 3.5; the epoxidation temperature is reduced to a certain degree, for example, the reaction temperature can be reduced by about 10 DEG C; and because too high temperature is needless, the fatty acid eater is not easy to be carbonized; the obtained product has light and bright color and luster and can be directly used for a light-color product without a decolorization process; the yield is also enhanced; and particularly the corrosivity to equipment is greatly reduced, thereby reducing equipment investment, maintainance and replacement. Meanwhile, the solid catalyst is simpler than a liquid catalyst in use and recovery aspects and is friendly to environment.
Owner:JIANGSU ZHONGSHENG GAOKE ENVIRONMENTAL CO LTD

Bifunctional starch-based composite nanoparticle as well as preparation method and application thereof

ActiveCN110606995ARich academic contentUniform degree of polymerizationFermentationComposite nanoparticlesINDUCTION TREATMENT
The invention discloses a bifunctional starch-based composite nanoparticle as well as a preparation method and an application thereof. The preparation method comprises the following steps: hydrolyzingstarch to form linear dextrin, and grading the linear dextrin by adopting an alcohol-alcohol gradient precipitation method to obtain linear dextrin with uniform molecular weight distribution; carrying out oxidation treatment on the linear dextrin through an oxidation system to obtain oxidized dextrin; carrying out complexation reaction on the oxidized dextrin and curcumin to form an oxidized dextrin-curcumin complex, so that the oxidized dextrin-curcumin / chitosan hydrochloride composite nanoparticles and chitosan hydrochloride form the oxidized dextrin-curcumin / chitosan hydrochloride composite nanoparticles. According to the method, the aqueous phase solution of the bifunctional starch-based composite nanoparticles containing the gellan is uniformly mixed with the primary emulsion, the obtained double emulsion is subjected to calcium ion induction treatment to obtain the double emulsion gel, and the double emulsion gel has good oxidation resistance and long-term storage stability andcan be applied to the fields of protection of nutritional ingredients, drug delivery, preparation of cosmetics and the like.
Owner:HEFEI UNIV OF TECH

Method for manufacturing inductive electric component, and inductive electric component

A method and electric component, such as inductor, coil, resistor, or the like, are disclosed wherein a winding includes at least one spiral or coiled element, the spiral or coiled element being formed from a piece furnished with cooling ribs.
Owner:ABB OY

Cross-linkable fluorine-containing sulphonated polyarylether compound and preparation method thereof

The invention belongs to the field of proton exchange membrane materials, and particularly relates to a cross-linkable fluorine-containing sulphonated polyarylether compound and a preparation method thereof. The preparation method comprises the following steps: first, performing polycondensation on decafluorobiphenyl, 2,2'-diallylbisphenol A and bisphenol A to prepare a cross-linkable fluorine-containing polyarylether compound; then, enabling the cross-linkable fluorine-containing polyarylether compound to react with a certain amount of sodium 4-hydroxybenzenesulfonate, so that sulphonic groups are introduced into a polymer; finally, preparing to obtain the cross-linkable fluorine-containing sulphonated polyarylether compound. The cross-linkable fluorine-containing sulphonated polyarylether compound can be cast into a membrane by using a solution. The obtained proton exchange membrane has the characteristics of simple preparation process, high heat stability, high oxidation stability,high proton conductivity, good mechanical properties and the like. A cross-linking type proton exchange membrane can be prepared by adding a free radical initiator, so that the solvent resistance is improved.
Owner:FUZHOU UNIV

Fish-skin degreasing method

The invention belongs to the field of aquatic product processing and specifically relates to a fish-skin degreasing method, which comprises the following steps of: immersing fish-skin, cutting into pieces, adding an alkaline lipase enzyme preparation which has pH value of 8.0 and vitality of 50-80U / mL and is 4-6 times as heavy as the fish-skin, carrying out enzymatic hydrolysis at 35+ / -2 DEG C for 25-85 min, heating up to 60-80 DEG C for killing enzyme, cooling to room temperature, filtering, washing off aliphatic acid and residual fat generated from enzymatic hydrolysis by using alkali lye, and washing off alkali lye and other impurities by using deionized water. The invention has advantages of simple technology, mild condition and high degreasing rate, and is suitable for expansion and mass production.
Owner:ZHEJIANG MARINE DEV RES INST

Graphene loaded MOF derivative aerogel and preparation method thereof

The invention discloses graphene loaded MOF derivative aerogel and a preparation method thereof. The aerogel is prepared from the following raw material components: graphene oxide, FeCl3. 6H2O, Ni (NO3) 2.6 H2O and phthalic acid, wherein the molar ratio of FeCl3. 6H2O to Ni (NO3) 2.6 H2O to phthalic acid is (1-3): (1-3): (1-3), and the mass ratio of Fe-Ni bimetallic MOF synthesized from FeCl3. 6H2O, Ni (NO3) 2.6 H2O and phthalic acid to graphene oxide is (1: 10)-(10: 1). The invention also provides the preparation method of the aerogel. The preparation method is mild and rapid, controllable incomponents and macroscopic in scale; the key technical problems that components and structures in a graphene / bimetal MOF and derivative composite system thereof are uncontrollable and the like are solved, and the prepared graphene loaded MOF derivative aerogel has wide application prospects in the fields of electro-catalytic energy storage, electromagnetic shielding, adsorption, sensing and the like.
Owner:NANJING UNIV OF INFORMATION SCI & TECH

Blend of carbon dioxide-propylene oxide copolymers and preparation method thereof

The invention provides a blend of carbon dioxide-propylene oxide copolymers, which comprises 5wt percent to 15wt percent of urethane compounds and 85wt percent to 95wt percent of carbon dioxide-propylene oxide copolymers. The urethane compounds are one kind of materials in compounds shown as from the formula I to the formula VI, wherein n is respectively 2, 4, 6 and 10, and R is methyl, ethide, propyl or butyl. Because molecules of small-molecular urethane compounds contain urethane bonds and / or hydroxide radicals and can be used as proton donors, and the carbon dioxide-propylene oxide copolymers contain carbonyls and can be used as proton acceptors, so the molecules of the urethane compounds can form stronger hydrogen bond effects with the carbon dioxide-propylene oxide copolymers, the compatibility is greatly improved, and further, the fraction elongation rate of the carbon dioxide-propylene oxide copolymers is effectively improved. The invention also provides the preparation method of the blend of the carbon dioxide-propylene oxide copolymers.
Owner:中科应化(长春)科技有限公司

Method for marking enveloped virus nucleocapsid by using quantum dot

The invention relates to a method for marking enveloped virus nucleocapsid by using a quantum dot. The method is characterized in that a capsid protein sequence blended with a biotin receptor peptide sequence and a catalytic receptor peptide biotinylation enzyme sequence are simultaneously inserted in a virus whole-genome so as to obtain a recombinant virus plasmid, the biotinylation of the nucleocapsid is realized by virtue of the reproduction process of the virus plasmid in a host cell, and then the quantum dot coupled with streptavidin is used for realizing the marking of the enveloped virus nucleocapsid. The method does not needs the violent chemical reaction transformation and the marking of a virus and is beneficial to the maintenance of infection activity of the virus self; and the marking of the nucleocapsid in the enveloped virus does not affect the surface of the enveloped virus and the indentation of the surface. The method can be applied to the virus infection mechanism study and the virus-related disease treatment research.
Owner:WUHAN UNIV

Preparation method of fermented traditional Chinese dealcoholic functional beverage

The invention provides a preparation method of a fermented traditional Chinese medicine dealcoholic functional beverage. The preparation method comprises the following steps: (a) preparation of seed fungi liquid, red date syrup and fragrant rice fermentation liquor for traditional Chinese medicine fermentation; (b) weighing traditional Chinese medicine recipe of a dealcoholic medicine; (c) fermenting and filtering the dealcoholic medicine traditional Chinese medicine. The traditional Chinese medicine fermented dealcoholic beverage prepared from the method and the preparation method provided by the invention have the advantages that the traditional Chinese medicine fermented dealcoholic beverage can fast alleviate the drunkenness, and the drunkenness can be alleviated within 1-3 hours according to the drinking amount; 2, the beverage can be for alleviating the hangover, and can be used as the body health beverage after the drunkenness; 3, the dealcoholic medicine provided by the invention is free from any chemical additive components, green, safe, and free of toxic and side effect; 4, the raw materials required by the preparation method provided by the invention are low in cost; 5, the traditional Chinese medicine dealcoholic beverage prepared from the method provided by the invention is good in color, flavor and the taste, and attractive for eating; 6, the preparation method provided by the invention is simple in process flow and suitable for industrial production.
Owner:LUOYANG NORMAL UNIV

Preparation method of monascus fermentation traditional Chinese medicine health wine with characteristic of no color fading

The present invention provides a preparation method of a monascus fermentation traditional Chinese medicine health wine with a characteristic of no color fading. The preparation method is characterized by comprising: a, preparing a seed bacterial liquid for traditional Chinese medicine fermentation, red dates for traditional Chinese medicine fermentation, and a traditional Chinese medicine extraction drug wine for traditional Chinese medicine fermentation; and b, preparing the traditional Chinese medicine fermentation drug wine. The method of the present invention has the following beneficial effects that: the traditional Chinese medicine extraction rate is increased, the drug wine use effect is increased, the drug consumption is reduced, the monascus active component synthesis is increased, the enzyme activity is improved, the obtained wine has characteristics of pleasant color, no color fading, mellow alcohol taste, rich taste, pleasant aroma, no bitter taste, disease prevention, enjoyment feeling, red and bright color, clarified and transparent wine liquid, aroma, mellow taste, concurrent color, aroma and taste provision, perfect health, color and taste integration, health effect, and drinking interest enjoying, the method has characteristics of low equipment investment requirement and low cost, and is suitable for large-scale industrial production, and the obtained product does not contain any chemical additive components and is green and natural.
Owner:LUOYANG NORMAL UNIV

Method for hastening parturition of shellfishes by sterilized and neutralized sea water

The invention relates to parturition hastening methods for shellfish products, in particular to a method for hastening parturition of shellfishes by sterilized and neutralized sea water. According to the method, outdoor sea water is sedimented in a sedimentation tank, sodium hypochlorite or bleaching powder are added for sterilization, sodium thiosulfate is used for neutralizing residual chlorine in the water, water in a nursery pond is firstly drained off during parturition hastening, the neutralized sea water is injected into the nursery pond until the sea water submerges seed shellfishes, air inflation and oxygenation are performed, the seed shellfishes are added immediately once spawning of the seed shellfishes is discovered, and the sea water is injected until the pond is filled with the sea water. The method is simple, and easy to implement. The method has the advantages of short time, high parturition hastening rate and good effect in terms of shellfish parturition hastening. The method belongs to methods for changing growing environmental conditions of the seed shellfishes, but the method is slow and gentle and does not cause intense stimulation and damage to the seed shellfishes. Indexes such as fertilized-egg hatching rate, metamorphosis rate and blood-shellfish repeating utilization factor are increased by 20% as compared with those in the prior art. The problems of shellfish source shortage and difficulty in seed breeding during shellfish product production are solved indirectly.
Owner:营口现代渔业科技产业园 +1

Method for extracting pigment from eleochairis toberosa peel

The invention discloses a method for extracting pigment from eleochairis toberosa peel. The method comprises the following steps: pretreatment; enzymatic hydrolysis: adding a disodium hydrogen phosphate buffer solution into the eleochairis toberosa peel, adding a compound enzyme in an amount which is 0.4 to 2.0 percent of the mass of the eleochairis toberosa peel, stirring for reacting for 1 to 3 hours at the temperature of 50 to 55 DEG C and at the speed of 700 to 850 rpm, and performing centrifugal filtering; adding the eleochairis toberosa peel undergone the enzymatic hydrolysis into an ethanol solution which is 50 to 70 percent in volume fraction, and performing ultrasonic microwave extraction to obtain a pigment product. The extraction method provided by the invention has a high flavone yield, and original bioactivity can be kept to the maximum extent at the same time; extracted flavone pigment has high stability, and high pigment quality; the method has the characteristics of mildness, high efficiency, easiness, convenience, low energy consumption and the like, has greater advantages when being applied to the field of extraction of natural pigment, and has a wide development prospect.
Owner:JIANGNAN UNIV

Extraction method of nonextractable polyphenol in blueberry

ActiveCN106901359ANo need to collect repeatedlyEasy to operateFood ingredient functionsAcetic acidAlcohol
The invention relates to an extraction method of nonextractable polyphenol in blueberry, and belongs to the technical field of extraction of plant polyphenol. The extraction method comprises the followings steps: preparing blueberry residue, preparing blueberry residue powder, performing acid solution soaking, performing alkali solution soaking, performing enzymolysis, centrifugation, extraction and collecting extractive. The extraction method is simple in operation steps, the operation steps can be performed in one container, and the extractive is not required to be repeatedly collected; weak concentration acid and alkali are adopted to treat materials, ethyl acetate and ethyl alcohol mixed liquor can be utilized for extracting, the method is mild, the bioactivity of the nonextractable polyphenol can be furthest reserved, the extraction ratio is improved, and the environmental pollution is very small.
Owner:TIANJIN AGRICULTURE COLLEGE

Coumarin-based light-CO2/N2 double stimuli-responsive surfactant, and preparation method thereof

The invention relates to a coumarin-based light-CO2 / N2 double stimuli-responsive surfactant, and belongs to the field of colloid and interface chemistry. The coumarin-based light-CO2 / N2 double stimuli-responsive surfactant is a coumarin-based bicarbonate surfactant. According to the preparation method, the coumarin-based bicarbonate surfactant is obtained by taking a dibromo alkane and 7-hydroxycoumarin as raw materials via O alkylation, ammoniation, and adding of carbon dioxide. The coumarin-based light-CO2 / N2 double stimuli-responsive surfactant possesses excellent surfactant performance, is responsive to ultraviolet light, visible light, CO2, and N2, and possesses double stimulative responsiveness.
Owner:JIANGNAN UNIV

Aromatic-ring C-H bond direct-amination reaction method of aromatic amides

ActiveCN107398300AEasy to realize direct amination reactionEnables direct amination reactionsOrganic chemistryOrganic-compounds/hydrides/coordination-complexes catalystsCopperOxygen
The invention relates to preparation methods for preparing aromatic amide compounds and particularly relates to an aromatic-ring C-H bond direct-amination reaction method of aromatic amides. The method provided by the invention has the characteristics of simplicity, convenience, high efficiency and the like and easily achieves the large-scale preparation of a compound represented by a formula 3 shown in the description. According to the method provided by the invention, a compound represented by a formula 1 shown in the description and a compound represented by a formula 2 shown in the description serve as raw materials, cheap divalent copper serves as a catalyst, oxygen in air serves as an oxidant, and an aromatic-ring C-H bond direct-amination reaction of the aromatic amides is achieved in a high-yield manner. According to the method provided by the invention, the defects of the general preparation of aromatic amides that a reaction substrate is required to be functionalized, a process is relatively tedious and the like are overcome, and the defects of high cost and difficulty in large-scale preparation caused by the additional adding of expensive oxidants such as Ag are also avoided. The method has the characteristics of simplicity, moderateness, relatively good functional group compatibility and the like and has a very good application value.
Owner:INST OF CHEM CHINESE ACAD OF SCI

Preparation method for tissue-derived carbon fiber loaded MoS2 microflower composite material and application in lithium-sulfur battery

The invention belongs to the technical field of new energy materials, and particularly relates to a preparation method for a tissue-derived carbon fiber loaded MoS2 microflower composite material andthe application in a lithium-sulfur battery material. The method comprises the following steps of: soaking a commercial tissue in hydrochloric acid for 24 hours and conducting washing with water and drying, dissolving ammonium molybdate tetrahydrate and thiourea in water to obtain a mixed solution, immersing the treated tissue into the mixed solution, carrying out hydrothermal treatment, washing with water, and drying to obtain a sample, and calcining the sample in an inert atmosphere to obtain the tissue-derived carbon fiber loaded MoS2 microflower composite material. The method of preparingthe commercial tissue derived carbon fiber loaded MoS2 microflower composite material is mild, raw materials are easy to obtain, the cost is low, many effective anchoring sites are achieved, and adsorption and catalytic conversion of LiPSs are facilitated. And the content of active substances is as high as 72%.
Owner:UNIV OF JINAN

Method for controllably synthesizing near-infrared Ag2Se nano crystal

The invention discloses a method for controllably synthesizing Ag2Se nano crystal. The method comprises the following steps of: obtaining low-valence Se in processes of simulating glutathione reductase in an organism outside cells and reducing sodium selenite (Na2SeO3) by using coenzyme, reacting the low-valence Se and Ag<+> coordinated with alanine in an inert atmosphere, and thus obtaining the Ag2Se nano crystal with good monodispersity, uniform particle size and different fluorescence emission wavelengths under the condition of aqueous phase. In the method, the size and the fluorescence emission wavelength of the product are controlled by controlling the ratio of the Se precursor to the Ag precursor. The method is easy and convenient, can be repeated for preparation, does not require inflammable, explosive and toxic metallic organic compounds, is good in safety, and can be applied in the fields of chemistry and material science more widely.
Owner:WUHAN UNIV

Controllable gradient stent loaded with drugs, active factors and cells, 3D printing method of controllable gradient stent and special multi-nozzle 3D printer

The invention relates to the technical field of biological tissue and organ 3D printing, in particular to a controllable gradient stent loaded with drugs, active factors and cells, a 3D printing method of the controllable gradient stent and a multi-nozzle 3D printer. The controllable gradient stent is formed through one-step alternate printing; the integrated gradient stent at least comprises twomaterials, namely a first material and a second material, wherein the first material is loaded with one or more of the drugs, the active factors or the cells; the second material is loaded with one ormore of the drugs, the active factors or the cells; and the first material and the second material are alternately printed to construct the integrated gradient stent. The integrated gradient stent constructed by the invention and loaded with the drugs, the active factors or the cells does not have the problems that a double-layer gradient interface is not firm and easy to fall off. The integratedgradient stent of the three-dimensional cells is constructed in a multi-nozzle alternate printing manner, and a foundation is provided for construction of complex tissues and organs of organisms.
Owner:SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI

Separation and purification method for spongy archaecyte

This invention relates to a separation and purification method for sponge dry cells-original cells, which utilizes four methods of differential centrifugation, specific agglutination of cells, differential adherence and centrifugation of density and grads together to increase the purity and efficiency of separation and purification of sponge original cells and provides an effective method for studying the biological property of exuberate film sponge dry cells and the vitro culture rule.
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI

Liposuction device for autologous fat transplantation of human body and usage method thereof

The invention discloses a liposuction device for autologous fat transplantation of the human body and a usage method thereof and belongs to the field of medical surgical operation devices. A fat quantification device and a fat storage device are arranged in an incubator, and a temperature sensor I and a temperature sensor II are arranged in a liposuction end head and the incubator respectively. A pressure pump switch for starting a pressure pump or not through controlling, a pressure display screen and a pressure regulating knob are all arranged on the pressure pump. A thin water body impact tube is arranged on a delivery pipeline between the fat quantification device and the fat storage device. A primary filter layer and a secondary filter layer are sequentially arranged in the fat storage device from top to bottom. A more suitable storage environment can be provided for fat cells, and keeping of the activity of the fat cells is promoted. Misoperations produced by excessive and easily mistaken switching and the situation that normal operation cannot be performed in time can be prevented. The keeping of the survival rate of the fat cells is promoted. The accuracy of fat quantification can be ensured, and collection and reutilization of the fat cells and residual materials are promoted.
Owner:JIANGSU VOCATIONAL COLLEGE OF MEDICINE
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