34 results about "Trimethoprim Lactate" patented technology

The invention relates to a compound doxycycline hydrochloride composition for preventing and treating colibacillosis and chronic respiratory disease of poultry as well as a preparation method of the compound doxycycline hydrochloride composition. The compound doxycycline hydrochloride composition is prepared by uniformly mixing the following components by weight: 10-15 parts of doxycycline hydrochloride, 10-20 parts of colistin sulfate, 5-15 parts of tylosin tartrate, 5-10 parts of trimethoprim lactate and 40-70 parts of anhydrous dextrose. The compound doxycycline hydrochloride composition has the beneficial effects of reasonable formula, easiness in preparation, remarkable treatment effect and clinically proven special effect for treating colibacillosis and chronic respiratory disease of the poultry.

The invention relates anti-flaming anti-bacteria coating. The anti-flaming anti-bacteria coating comprises the following materials, by mass, 6-10 parts furfuryl alcohol resin, 15-30 parts of butylated hydroxyanisole, 8-16 parts of polyhexamethylene guanidine, 10-25 parts of zirconite powder bodies, 8-10 parts of trimethoprim lactate, 4-10 parts of bismaleimide resin, 12-20 parts of antimonous oxide, 0.5-1 part of cobalt blue, 0.1-0.5 part of chlorothalonil, 5-15 parts of magnesium stearate, 1-3 parts of isophorone diisocyanate and 30-100 parts of deionized water. The preparation process of the anti-flaming anti-bacteria coating is conducted under normal temperature, no new equipment is needed to be added, the technology is simple, and the cost is low. After the anti-flaming anti-bacteria coating is used, not only can the antibacterial property on the surface of a material be effectively improved, but also the anti-flaming property is good.

The invention discloses compound rifaximin nanoemulsion, which is prepared from the following raw materials in percentage by mass: 30 to 45 percent of surfactant, 1 to 10 percent of cosurfactant, 1 to 16 percent of oil phase, 0.1 to 5 percent of rifaximin, 0.025 to 1.25 percent of trimethoprim lactate and the balance of deionized water. The sum of the mass percentage of the raw materials is 100 percent. The compound rifaximin nanoemulsion is applied to acute and chronic intestinal infection, diarrhea syndrome, diarrhea caused by intestinal flora change, hepatic encephalopathy and the like, obviously improves the bioavailability and stability of rifaximin, is quick in response, lasting in effect and high in safety, and has a wide market prospect in the field of medicines.

The invention discloses compound amoxicillin soluble powder for treating duck oromeningitis and a preparation method thereof, aiming at providing soluble powder which has high effect on treating duckinfection, reduces germ medicine resisting probability and treats both principal and secondary aspects of diseases; and the invention also discloses a preparation method of the composition. The compound amoxicillin soluble powder for treating duck oromeningitis comprises the following components by weight percent: 2-20 percent of amoxicillin, 2-20 percent of sulfamonomethoxine sodium, 0.4-4 percent of trimethoprim lactate, 2-10 percent of sodium dichlorophenolate, 1-8 percent of natrium carbonicum calcinatum and the balance of anhydrous dextrose. The compound amoxicillin soluble powder combines the amoxicillin and the sulfamonomethoxine sodium, can greatly reduce the medicine resistance of duck Riehmer bacillus, increase pathogeny resisting capability, has a stronger inhabiting or killingfunction and can prevent other secondary bacterial infection, and meanwhile, the trimethoprim lactate can effectively increase the antibacterial capability of the amoxicillin and the sulfamonomethoxine sodium, greatly enhance an antibacterial function, kill pathogeny and relieve clinical symptoms after being combined with the functions of refrigeration and inflammation resistance of the sodium dichlorophenolate.

The invention discloses a composite saponification cutting liquid which consists of the following raw materials in parts by weight: 2-3 parts of oleic acid, 0.1-0.2 part of trimethoprim lactate, 3-5 parts of sodium myrastate, 0.2-0.4 part of p-nitrophenol, 0.1-0.2 part of polyoxyethylene castor oil, 0.3-0.5 part of potassium hydroxide, 0.2-0.3 part of carboxylic acid glyceride, 5-7 parts of polyethylene glycol diglycidyl ether, 10-13 parts of raw silk, 10-16 parts of polymaleic anhydride, 0.8-2 parts of span-80 and 170-200 parts of deionized water. The fibroin emulsion takes silk as a main material, is non-toxic and free of pollution and high in lubrication property, polyoxyethylene castor oil can be adopted for modification, the flexibility, the hydrophilia and the stability of the emulsion in membrane preparation can be improved, and polymaleic anhydride which is finally added can be adhered to the surface of the membrane, so that the membrane can be immobilized, air can be isolated, and a further anti-rusting function can be achieved. The composite saponification cutting liquid with the cutting liquid is excellent in extreme-pressure wearing resistance, and long-lasting anti-wearing and rusting protection can be achieved.

The invention discloses a composition for treating poultry digestive tract bacterial infection and a preparation method thereof, and aims to provide a composition for treating poultry digestive tract infection, treating the root cause and symptoms of disease and reducing medicament-resistant probability and a preparation method thereof. The composition consists of the following raw materials in percentage by weight: 5 to 15 percent of florfenicol, 5 to 15 percent of sulfamonomethoxine sodium, 5 to 15 percent of taurine, 1 to 3 percent of trimethoprim lactate, 5 percent of sodium chloride, 5 percent of potassium chloride and the balance of anhydrous dextrose. The florfenicol and the sulfamonomethoxine sodium serving as antibacterial components have double effects and can effectively avoid the medicament resistance of bacteria; and the composition can be absorbed and avoid destroying beneficial bacteria in the intestinal tract. The lactate TMP (trimethoprim lactate) has synergistic effect on the florfenicol and the sulfamonomethoxine sodium; the taurine with anti-inflammatory effect is acted on the digestive tract, does not injure the function of the gastrointestinal tract and is favorable for treating intestinal inflammation; and the combination of the sodium chloride and the potassium chloride has complementing effect on electrolyte loss caused by great defecation of sick poultry.

The invention discloses compound levofloxacin hydrochloride soluble powder for treating respiratory diseases of poultry. The soluble powder is prepared by uniformly mixing the following components in percentage by weight: 2-10 percent of levofloxacin hydrochloride, 2-10 percent of azithromycin, 2-6 percent of venenum bufonis, 10-30 percent of liquorice extract, 3-9 percent of Kameiding, 1-5 percent of trimethoprim lactate, and the balance of pharmaceutically applicable auxiliaries. The compound preparation is compounded by latest market medicines, traditional Chinese medicinal extracts, novel antiasthmatic drugs and medicinal synergistic agents, and fatal factors are comprehensively taken, so that the compound levofloxacin hydrochloride soluble powder has the effects of anti-inflammation, sterilization, anti-virus, heart strengthening, cough relieving and allergic reaction resistance, can be used for improving the anti-disease immunity of poultry, repairing injured mucous membrane and effectively controlling secondary infection, and has an effective treatment effect to respiratory diseases of poultry.

The invention discloses a veterinary tilmicosin premix powder drug, belonging to the technical field of veterinary drugs. The veterinary tilmicosin premix powder drug provided by the invention is composed of tilmicosin, trimethoprim lactate and anhydrous glucose. According to the invention, through combination of the tilmicosin and a synergist, the whole powder is reinforced in treatment effect; and the veterinary tilmicosin premix powder drug can be used for treating infectious pleuropneumonia, plague, enzootic pneumonia and the like of pigs or cattle. The veterinary tilmicosin premix powderdrug provided by the invention is rapid to be absorbed after being taken orally, has the characteristics of strong tissue penetrating power, high lung concentration and long effective blood concentration maintaining time, has stable preparation, and is simple in preparation process and convenient to use.

The invention relates to a compound neomycin sulfate composition for treating pet abscess and a preparation method of the compound neomycin sulfate composition. The composition is prepared by uniformly mixing the following components by weight: 1-3 parts of neomycin sulfate, 3-5 parts of erythromycin thiocyanate, 1-2 parts of trimethoprim lactate, 1-3 parts of cetrimonium bromide, 3-5 parts of piperitol, 50-70 parts of liquid paraffin, 7-9 parts of glycerol, 0.4 part of ethylparaben, 1-3 parts of essence, 80-113 parts of distilled water and the like. The compound neomycin sulfate composition has the beneficial effects that the formula is reasonable, preparation is simple, curative effects are very remarkable, and furthermore, clinical application show that the compound neomycin sulfate composition has special effect for treating pet abscess.

The invention discloses a boron-carbide-filled modified plastic which is prepared from the following raw materials in parts by weight: 100 parts of low density polyethylene, 4.5-6.8 parts of nano antimony tin oxide, 1-2 parts of nano titanium white, 2-3 parts of epoxy soybean oil, 1-3 parts of straw ash, 0.4-0.8 part of nano silicon dioxide, 0.1-0.3 part of trimethoprim lactate, 0.2-0.4 part of barium chromate, 0.4-0.5 part of boron carbide, 1.2-1.6 parts of maleic anhydride graft compatilizer and a right amount of anhydrous ethanol. The manufacturing method comprises the following steps: adding the nano materials into the coupling agent, activating by stirring, uniformly mixing with the linear polyethylene, nano silicon dioxide, boron carbide and the like, and carrying out melt extrusion granulation with a double screw extruder. The prepared plastic has the characteristics of favorable wear resistance, favorable heat stability, ultraviolet irradiation resistance, aging resistance, high strength and higher chemical resistance. When the modified plastic is subjected to deep processing into a plastic film for vegetable greenhouses, the plastic film has the advantages of short degradation period, favorable low-temperature resistance, obvious heat insulation effect, self-cleaning function, bacteria resistance and high light transmittance.

The invention discloses a method for preparing a veterinary tilmicosin premix powder medicine, and belongs to the technical field of veterinary medicines. The method comprises the following steps: respectively crushing and sieving tilmicosin, trimethoprim lactate and anhydrous glucose; weighing tilmicosin and trimethoprim lactate two raw materials, adding anhydrous glucose, and performing pre-mixing; and then adding anhydrous glucose and performing full mixing to obtain the medicine. The medicine adopts the combined medication of tilmicosin and a synergist, the combination of the two enhancesthe therapeutic effect of the whole powder, and the medicine can be used to treat infectious pleuropneumonia, lung plague, asthma diseases and the like of pigs or cattle. The absorption of the medicine is quick after oral administration, and the medicine has the characteristics of strong tissue penetration, high concentration in lung, and long effective blood concentration maintaining time. Moreover, the preparation is stable, the preparation process is simple, and the use is convenient.

The invention belongs to the technical field of animal medicines, and in particular discloses compound oral liquid for treating poultry colibacillosis mixed infection. Each 100L of compound oral liquid for treating poultry colibacillosis mixed infection consists of the following components: 15 to 25L of heartleaf houttuynia herb distillate, 0.5 to 1kg of amikacin sulfate, 0.5 to 1kg of gentamicinsulfate, 0.05 to 0.2kg of trimethoprim lactate, 3 to 8kg of nicotinamide, 0.01 to 0.05kg of dexamethasone sodium phosphate, 0.1 to 0.3kg of sodium hydrogensulfite, 0.1 to 0.5L of lactic acid and the balance of purified water. The compound oral liquid for treating poultry colibacillosis mixed infection has the advantages that: antibacterial and antiviral effects are obvious, and poultry persistentfever symptoms caused by poultry colibacillosis mixed infection can be relieved, so that the organism function of poultry is quickly recovered; and the oral liquid has quick response and an obvious curative effect and is conveniently and safely used.

The invention discloses a compound preparation for treating cholestatic jaundice and a preparing method thereof. The compound preparation is prepared from ademetionine 1,4-butanedisulfonate, diammonium glycyrrhizinate, dihydroxydibutylether, baicalin, methionine, anethol trithione, potassium magnesium aspartate, crocetin dimethyl ester, glucurolactone, cholestyramlne, hydroxymethylnicotinamide, trimethoprim lactate, bumetanide, piperazine citrate and azathioprine. The compound preparation has the effects of resisting bacteria and diminishing inflammations, clearing dampness and heat, soothing the liver and benefiting the gallbladder, removing the toxicity and eliminating jaundice and strengthening the spleen and the stomach, can reduce stasis of bile in liver cells, promote bile excretion, improve the liver functions and the tissue cell respiration function, reduce accumulation of fat in the liver and promote jaundice elimination and liver function recovery and is significant in treatment effect, safe and few in side effect when the compound preparation is used for treating the cholestatic jaundice and complications thereof.

The invention disclosed a kind of compound sulphuric acid berberine injection as well as its preparing method. The compound sulphuric acid berberine injection includes the following ingredients: 5-30 shares of suphuric acid berberine, 5-35 shares of mequindox, 1-25 shares of lactic acid trimethoprim and 0.5-2 shares of atrop; the preparing procedure includes the following steps: weighting ingredients; putting mequindox into the water for injection at 40-50DEG C; adding certain amount of auxiliary solvent, stirring for 10min to the solution is clear; putting lactic acid trimethoprim and atrop I to the previous solution, stirring and regulating the pH value; putting activated char into the solution and stirring for 15-20min, adding water for injection to 1000 shares to get the product. The invention can be widely used to treat the diarrhea caused by swine dysentery bacilli, increase its immunity and increase the body weights.

The invention discloses a composition for treating chicken necrotizing enterocolitis and a preparation method thereof and aims to provide a composition for treating chicken necrotizing enterocolitis infection with rapid desired effect, bacterium drug-resistant reduction and both principal and secondary treatment of diseases and a preparation method thereof. The composition for treating chicken necrotizing enterocolitis is prepared by the following raw materials in percentage by weight: 2-10 apramycin sulfate, 2-15 sodium orosulfan, 0.4-3 trimethoprim lactate, 0.1-0.5 atropine sulfate and the balance of tannic acid. The composition adopts two phytopathogenic components, i.e. the apramycin sulfate and the sodium orosulfan, wherein the apramycin sulfate taken orally is difficult to absorb andgenerates contact sterilization, the sodium orosulfan taken orally takes effect by humoral secretion, and pathogens are killed in two ways. The antibacterial effects of the apramycin sulfate and thesodium orosulfan are enhanced by the trimethoprim lactate, the atropine sulfate reduces glandular secretion, and the tannic acid forms a protective film with protein to prevent bacteria from contacting the intestinal canal and effectively protect the intestinal mucosa.

The invention relates to a compound gentamicin sulphate composition for treating poultry diarrhea. The compound gentamicin sulphate composition is characterized by being prepared by mixing the following components by weight part: 5-10 parts of gentamicin sulphate, 10-15 parts of ciprofloxacin, 10-20 parts of berberine hydrochloride, 5-9 parts of trimethoprim Lactate salt and 46-70 parts of glucosum anhydricum. The compound gentamicin sulphate composition has the beneficial effects of reasonable formula, simple preparation, extremely obvious curative effect and special effect on the treatment of poultry diarrhea through clinical proving.

The invention discloses a medicine compound used to prevent and treat infectious serositis of ducks. The medicine compound is prepared by the following compositions that: each 100g of the medicine compound contains 5 to 10g of sodium sulfamethoxazole, 1 to 2g of trimethoprim lactate, 5 to 10g of mequindox, and the balance being pharmaceutically acceptable auxiliary materials. The invention provides the broad livestock industry with the medicine compound used to prevent and treat the infectious serositis of the ducks; the medicine compound has a simple preparation method, remarkable healing effect, simple and convenient use, and wide application range.

The invention relates to florfenicol powder for improving water solubility as well as a preparation method and an application of the florfenicol powder. The powder is composed of the following components in parts by weight: 10 parts of florfenicol powder, 3-5 parts of citric acid, 2-3 parts of polyvinylpyrrolidone PVPK30, 50-60 parts of lactose, 2-4 parts of sodium lauryl sulfate, 5-7 parts of polyethylene glycol 6000, 2-3 parts of trimethoprim lactate and 2-4 parts of palm oil. Polyethylene glycol 6000, citric acid, polyvinylpyrrolidone PVPK30, lactose, sodium dodecyl sulfate and the palm oilare adopted, and various components are synergetic to improve water solubility of florfenicol and trimethoprim lactate, so that the curative effect of the florfenicol powder is optimal.

The invention relates to a compound sodium sulfaquinoxaline composition for treating coccidiosis in young rabbits. The compound sodium sulfaquinoxaline composition is prepared by mixing the following ingredients in parts by weight: 0.5-1 part of toltrazuril, 4-6 parts of sodium sulfaquinoxaline, 0.8-1.2 parts of trimethoprim lactate, 15-25 parts of sodium citrate, 1.5-2.5 parts of sodium carboxymethyl cellulose, 0.2-0.5 part of sodium sulfite, 0.2-0.5 part of EDTA (Ethylene Diamine Tetraacetic Acid)-2Na, and a plurality of parts of distilled water. The compound sodium sulfaquinoxaline composition has the beneficial effects of being reasonable in formula, and simple to prepare, unique in medicine application mode, obvious in curative effect, and having special effects in treating the coccidiosis in young rabbits, proved clinically.

The invention relates to a preparation method of a tulathromycin oleaginous injection. A cosolvent is glycerolformal / benzyl benzoate / oleaginous medium, the oleaginous medium includes ethyl oleate and isopropyl myristate, and the preparation also contains hydrogenated castor oil and soybean lecithin. The cosolvent can be utilized to prepare a compound preparation of tulathromycin and trimethoprim. The preparation has good stability, good physiological tolerance, and high load capacity, and is a sustained / rapid release oleaginous injection for animals.

The invention belongs to a composition for treating poultry enteritis type colibacillosis in veterinary medicines. The preparation consists of the following components in percentage by weight: 3.25 percent of neomycin sulfate, 0.81 percent of lactate TMP (trimethoprim lactate), 10 percent of glutamine, and 85.94 percent of auxiliary glucose, wherein neomycin sulfate, lactate TMP and glutamine are main drug components. The veterinary composition is used for treating poultry enteritis type colibacillosis. The processing process of the composition comprises the following steps: respectively crushing and screening each component, and accurately weighing according to the required proportion; mixing for 25 minutes; inspecting a semifinished product; subpackaging, packaging and inspecting the finished product. According to the usage method, the composition is drunk in a ratio of 1 percent, and four days are taken as a course of treatment. The composition has a remarkable curative effect on poultry enteritis type colibacillosis, is low in drug tolerance, safe and low-toxic, and has good popularization and application values.

The invention discloses a composition for treating fowl enterovirus syndrome and a preparation method thereof, which aim at providing a composition with a good curative effect on integrally treating the fowl enterovirus syndrome and the preparation method thereof. The composition consists of the following ingredients in percentage by weight: 5 to 20 percent of sulfaquinoxaline sodium, 5 to 15 percent of ciprofloxacin hydrochloride, 1 to 4 percent of trimethoprim lactate, 1 to 5 percent of vitamin K3, 5 to 20 percent of sodium bicarbonate and the balance anhydrous dextrose. The adopted sulfaquinoxaline sodium has the strong effects on giant eimeria, eimeria brunette, eimeria acervulina and the like, and the synergia effect of the trimethoprim lactate is used as the auxiliary, so the eimeria resistance capability is greatly enhanced. The ciprofloxacin hydrochloride has the strong force on the bacterial infection in the enterovirus syndrome, and the killing effect is realized. The two effects are combined, and the pathogen causing the enterovirus syndrome can be targeted to be killed. The vitamin K3 can be used for controlling the intestinal tract bleeding caused by the enterovirus syndrome and reducing the side effect caused by the intestinal tract bleeding. The sodium bicarbonate can be used for reducing the kidney injury to the fowl caused by the sulfaquinoxaline sodium.

The invention relates to a compound norfloxacin nicotinate soluble powder for animals. A formula of 100g of the powder comprises 5-10g of norfloxacin nicotinate, 5-10g of apramyein sulfate, 2-4g of trimethoprim lactate, and the balance anhydrous glucose. The above medicine can rapidly kill intestinal pathogenic microorganisms to timely effectively control intestinal bacterial diseases of the animals, and alleviates the bacterial drug resistance.

The invention relates to a compound erythromycin thiocyanate composition for controlling poultry bacterial and mycoplasma infection and a preparation method thereof. The composition is prepared by uniformly mixing the following components according to parts by weight: 10-15 parts of erythromycin thiocyanate, 10-20 parts of neomycinsulphate, 4-7 parts of trimethoprim lactate and 58-76 parts of anhydrous dextrose. The compound erythromycin thiocyanate composition for controlling poultry bacterial and mycoplasma infection has the beneficial effects of being reasonable in composition, simple for preparation and very obvious in curative effect, and has specially good effect for curing poultry bacterial and mycoplasma infection through clinical application.

The invention relates to a preparation method of a tulathromycin oleaginous injection. A cosolvent is glycerolformal / benzyl benzoate / oleaginous medium, the oleaginous medium includes ethyl oleate and isopropyl myristate, and the preparation also contains hydrogenated castor oil and soybean lecithin. The cosolvent can be utilized to prepare a compound preparation of tulathromycin and trimethoprim. The preparation has good stability, good physiological tolerance, and high load capacity, and is a sustained / rapid release oleaginous injection for animals.

The invention relates to a compound norfloxacin nicotinate soluble powder for animals. A formula of 100g of the powder comprises 5-10g of norfloxacin nicotinate, 5-10g of apramyein sulfate, 2-4g of trimethoprim lactate, and the balance anhydrous glucose. The above medicine can rapidly kill intestinal pathogenic microorganisms to timely effectively control intestinal bacterial diseases of the animals, and alleviates the bacterial drug resistance.