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871 results about "Polypill" patented technology

A polypill is a medication that is a drug product in pill form (i.e., tablet or capsule) that combines multiple active pharmaceutical ingredients. The prefix "poly" means "multiple", referring to the multiplicity of distinct drugs in a given "pill". An occasional synonym is combopill. It is commonly manufactured as a fixed-dose combination (FDC) drug product targeting treatment or prevention of chronic disease. Polypills may be aimed to be consumed by healthy people as a means of preventive medicine, and/or treating actual pathophysiological condition(s), the former typically involving lower dosages than the latter. Polypills can reduce the number of tablets or capsules (generally orally administered) that need to be taken, which in turn may facilitate handling and administration of pharmaceuticals as well as alleviate patient pill-burden. Sometimes the multiple drugs in a given polypill might all be aimed at a single underlying condition (or, group of related conditions), partly because this expands the pool of potential patients for whom a given combination of drugs/dosages might be appropriate (particularly in the case of mass-produced polypills, i.e. FDCs). The term polypill was first coined in the context of cardiovascular disease prevention, but has since gained broader acceptance, including now for combinatorial drug products that existed before the term was actually coined (as the bare term without any modifiers is now quite generic).

Preparation and quality detection method of compound prescription cortex phellodendri chinensis fluid

The invention discloses preparation and quality detection method of compound prescription cortex phellodendri chinensis fluid. The quality detection method comprises the identification of forsythia fruit, cortex phellodendri, honeysuckle and dandehon herb, the checking of lonicerae flos, and the content determination of forsythin and berberine hydrochloride. According to the determination method, spots with the same colors are formed in a qualified test article thin-layer chromatogram and in corresponding positions of a reference substance thin-layer chromatogram, and negative control is interference-free, and the method is good in selectivity, simple and accurate. The checking method of lonicerae flos adopts a high performance liquid chromatography, is good in specificity, and can distinguish the situation that lonicerae flos is adopted in the compound prescription cortex phellodendri chinensis fluid to pretend honeysuckle flower to charge material. The content determination of forsythin and berberine hydrochloride is good in linear relation and high in recovery test accurancy, has good repeatability and stability, can accurately and strictly detect the quality of the compound prescription cortex phellodendri chinensis fluid, and guarantees a high quality standard level of the compound prescription cortex phellodendri chinensis fluid.
Owner:SHANDONG HANFANG PHARMA

Chinese medicine positioning preparation for curing ulcerative colitis

The present invention relates to a Chinese medicine location preparation for curing ulcerative colitis. It is formed from colon location capsule and Chinese medicine compound preparation for curing ulcerative colitis which is held in the capsule. Said capsule does not disintegrated in the stomach and small intestine, and in the colon region whose pH value is greater than or equal to 7.8 it is disintegrated, and the medicine can be released. Said invention can effectively raise the biological utilization rate of the medicine, and its therapeutic effect is obvious. After the prescription of said medicine is changed, it can be used for curing other disease of colon region.
Owner:BEIJING ZHONGHUI PHARM CO LTD

Preparation method for compound preparation comprising aspirin and alkaline drugs

The invention relates to a preparation method for a compound preparation comprising aspirin and alkaline drugs. The main technical points of the invention are that: the aspirin is prepared by dry granulation; the granulated aspirin and granules prepared by alkaline medicaments are pressed into double-layer tablets by a double-layer tablet machine; and then the double-layer tablets are coated. The aspirin is not stable and is easily hydrolyzed to generate free salicylic acid, so the dry granulation is adopted; the prepared double-layer tablets can prevent that the alkaline drugs quicken hydrolyzation of the aspirin; and the prepared coated tablets can be moistureproof, prevent that double layers of the double-layer tablets from being separated or expanded, and guarantee quality and stablity of products.
Owner:北京迈劲医药科技有限公司

Total triterpene of garden burnet root with anti-inflammatory and analgesic effects and preparation method thereof

The invention belongs to the technical field of medicaments, and provides a method for preparing total triterpene of Chinese medicament garden burnet root. The total triterpene is mainly obtained by performing reflux extraction by 70 percent ethanol, absorbing by a macroporous absorbent resin, using water to wash off impurities, using ethanol solution for elution, then decolorizing an eluent by daiamid powder, using the ethanol solution for elution, and recovering the ethanol through pressure reduction. The total triterpene mainly contains triterpenic acid active components such as arjunic acid, 1beta-euscaphic acid, euscaphic acid, tormentic acid and the like, and triterpenoid saponin active components such as sanguisorbin I, sanguisorbin II, sanguisorbin III, niga-ichigoside, kaji-ichigoside F1 and the like. Experimental results show that the total triterpene has remarkable anti-inflammatory and analgesic effects. The total triterpene has definite action substance basis and action mechanism as well as simple preparation technology, is suitable for industrialized production, can be taken as medicinal raw materials for treating inflammatory diseases such as burn and scald, rectitis, ulcerative colitis, pyelonephritis and the like, and is prepared into clinically acceptable dosage forms such as tablets, capsules, granules or compound preparations according to the prior process.
Owner:SHENYANG PHARMA UNIVERSITY

Traditional Chinese medicine compound preparation for treating cold, influenza and upper respiratory tract infection

The invention relates to a traditional Chinese medicine compound preparation for treating cold, influenza and upper respiratory tract infection and a preparation method thereof. The traditional Chinese medicine compound preparation comprises the following active ingredients in percentage by weight: 10 to 15 percent of honeysuckle, 15 to 20 percent of radix puerariae, 10 to 15 percent of baikal skullcap root, 10 to 15 percent of radix isatidis, 10 to 15 percent of radix bupleuri, 10 to 15 percent of forsythia, 8 to 12 percent of cyrtomium fortunei, 5 to 8 percent of angelica dahurica and 5 to 8 percent of balloon flower. The preparation is in forms of granules, capsules, tablets and the like, has the functions of dispelling pathogenic wind from muscles, clearing away heat and toxic materials and relieving sore throat and a cough, and mainly treats symptoms such as fever, typhoid, body pain, snuffles, nose running, dry throat, pharyngalgia, cough, skin eruption, swelling and ulcer and the like caused by affection of exogenous wind-heat, cold and lung and stomach heat. The traditional Chinese medicine compound preparation has obvious treatment effect, fewer side effects, no damages to the liver and the kidney, and fragrant and sweet taste, children like to take the preparation and the preparation can be applied to the treatment of virus infection and the bacterial infection of children.
Owner:WUHAN LANGJI PHARMA IND

Novel antitumor application of maggot

The invention provides a novel antitumor application of maggot. The novel application is an application of maggot in the preparation of antitumor medicines or health products. According to the invention, an effective part of the whole worm of maggot is used to prepare any one single medicine or compound preparation which is applicable to be used in clinic. The single medicine or compound preparation is an oral medicine or health product. The oral medicine or health product is tablets, capsules, pills, a particulate agent, an oral liquid, microcapsules, an injection, an inhalant or a powder. Auxiliary materials are selected from conventional solvents, excipients, flavoring agents, coloring agents, adhesives, lubricants, wetting agents, thickening agents or antiseptics. It proves through experiments that maggot can effectively inhibit growth of tumor cells, has a remarkable effect of killing tumor cells, and has good medicinal and health-care value.
Owner:SICHUAN HETAI SYNLIGHT BIOTECH LTD

Gel binder for treating swelling and pain and its preparation method

The invention relates to a compound preparation of an external use pharmaceutical composition for treating swelling and pain, which is a gel binder for treating swelling, and also provides its preparation method. The gel binder is prepared by 20-50% of swelling and pain medicine of the external use pharmaceutical composition for treating swelling and pain as well as proper pharmaceutical excipients. The gel binder for treating swelling is composed of a back lining layer, an ointment-containing body and a cover lining layer. The ointment-containing body, namely the kernel part, is prepared from the swelling and pain medicine, a basic polymer, a cross-linking agent, an organic acid, an excipient, a humectant, an adhesive and the like in certain ratio. The gel binder has the advantages of fast effect, good moisture preservation, high permeability and comfortable use. The product has merits of convenient usage, small irritation on skin and high compliance of patients.
Owner:YUNNAN INST OF MATERIA MEDICA

Purple bergenia element pentaacetylate and its uses

InactiveCN1733765AOvercomes weak antitussive and antiasthmatic effectsOvercome absorbencyOrganic active ingredientsOrganic chemistryCurative effectAcetylation
The invention provides a Bergenini penta-acetyl, whose chemical name is (2R,3R,4R,4aS,10bS)-2-(acetoxymethyl)-9-methoxy-6-oxo-2,3,4,4a,6,10b-hexahydr o pyrano[3,2-c]isochromene-3,4,8,10-tetrayl tetraacetate, and is prepared from Bergenini as lead compound through butanoylation reaction, the hydroxyl on the precursor is blocked so as to enhance the lipophilicity. The Bergenini penta-acetyl can be used for preparing medicine for relieving cough. The invention further provides a compound preparation containing the Bergenini penta-acetyl.
Owner:王刚 +2

Composition of thymic peptide alpha 1 and thymopeptide-5 and preparation method thereof

The invention relates to a composition of thymic peptide alpha 1 and thymopeptide-5 and a preparation method thereof. The compound preparation can be used for the treatment of chronic hepatitis B andvarious diseases with damaged immunological functions and the auxiliary treatment of tumours. The composition mainly comprises 0.1-10mg of thymic peptide alpha 1 and 0.1-100mg of thymopeptide-5. Simultaneously, proper auxiliary materials are added into the composition to prepare injection liquid or a freeze-drying medicament form. The composition prepared according to the proportion has obvious synergy action and can reach a better curative effect dose ratio for the treatment of the chronic hepatitis B and various diseases with damaged immunological functions and the auxiliary treatment of thetumours.
Owner:HAINAN ZHONGHE PHARM CO LTD

Medicinal composition for treating skin injury and quality detection method

The invention relates to a big compound Chinese medicinal preparation and a quality detection method thereof. A medicinal composition for treating the skin injury, which is disclosed by the invention, is external liniment prepared from the following 94 raw material medicaments in part by weight: 25 parts of rhizoma coptidis, 25 parts of red paeony roots, 75 parts of rhubarb, 75 parts of divaricate saposhnikovia roots, 44 parts of angelica dahurica, 13 parts of heracleum hemsleyanum diels, 13 parts of incised notopterygium rhizome, 19 parts of rhizoma arisaematis, 25 parts of ligusticum chuanxiong, 25 parts of common bletilla pseudobulb, 50 parts of common burreed rhizome, 75 parts of clematis roots, 50 parts of zedoary, 75 parts of combined spicebush roots, 100 parts of frankincense, 13 parts of cyperus rotundus, 25 parts of rhizoma drynariae, 75 parts of Indian iphigenia bulb, 25 parts of peach seed, 100 parts of common cnidium fruit, 25 parts of siberian cocklour fruit, 50 parts of castor bean, 75 parts of water banyan, 25 parts of tangerine peel, 25 parts of green tangerine peel, 25 parts of pummelo peel, 50 parts of gardenia, 13 parts of fructus amomi, 75 parts of hiraute shiny bugleweed herb, 50 parts of tamariskoid spikemoss herb, 50 parts of yerbadetajo herb and the like. By repeated compositional experiments, the compound Chinese medicinal preparation accords with the traditional Chinese medicine composition and compatibility principle; in the compound preparation, the medicaments are complemented with each other and can comprehensively take the effects; and the medicinal composition has an obvious treatment effect in scalding by water and fire, traumatic injuries, bleeding knife wounds and the like and has no obvious toxic or side effects.
Owner:广西梧州三鹤药业股份有限公司

Preparation process and quality control method of poria cocos, cassia twig, bighead atractylodes rhizome and liquorice decoction material reference

The invention relates to a preparation process and a quality control method of a poria cocos, cassia twig, bighead atractylodes rhizome and liquorice decoction material reference. According to the invention, through systematic historical research on prescriptions, an ancient method and a modern extraction method are combined, single factor investigation is adopted, and a preparation process and adrying process of the poria cocos, cassia twig, bighead atractylodes rhizome and liquorice decoction and the material reference thereof are optimized. Furthermore, poria cocos, cassia twig, bighead atractylodes rhizome and liquorice in the material reference are identified by adopting thin-layer chromatography, a fingerprint spectrum with good separation degree and reproducibility is established by adopting high performance liquid chromatography, and liquiritin, cinnamic acid and cinnamaldehyde are quantitatively researched by adopting the high performance liquid chromatography. According to the established preparation process and the quality standard research method of the poria cocos, cassia twig, bighead atractylodes rhizome and liquorice decoction material reference, a systematic research basis is provided for reasonable development of the compound preparation.
Owner:JIANGSU KANION PHARMA CO LTD
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