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Traditional Chinese medicine compound preparation for treating cold, influenza and upper respiratory tract infection

An influenza and upper respiratory tract technology, applied in anti-infective drugs, pharmaceutical formulations, respiratory diseases, etc., can solve the problems of not much anti-upper respiratory tract virus, unsatisfactory effect, and staying, and achieve good bacteriostatic effect.

Inactive Publication Date: 2011-04-06
WUHAN LANGJI PHARMA IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

3. Vaccines are an important measure to prevent viruses. In recent years, they have developed rapidly, such as live vaccines, inactivated vaccines, nucleic acid vaccines, etc., but their effects are not satisfactory at present. The reason is that the influenza antigens continue to mutate, and the vaccines fail.
But so far, the research on the pharmacological effects of Chinese patent medicines for preventing and treating influenza still stays in anti-inflammatory, antipyretic, analgesic, improving clinical symptoms, etc., and there are not many studies on the pharmacological effects of upper respiratory viruses. There is a need for new Chinese patent medicines for influenza that can improve symptoms and resist upper respiratory viruses

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0038] Example 1: Preparation of active ingredient volatile oil and extract

[0039] Recipe: Honeysuckle 300g, Pueraria 450g, Scutellaria baicalensis 300g, Banlangen 300g, Bupleurum 300g, Forsythia 300g, Guanzhong 250g, Angelica dahurica 150g, Campanulaceae 150g

[0040] Crush bupleurum, scutellaria baicalensis, and forsythia into coarse powder, add water to cook to extract volatile oil, collect volatile oil for later use, filter, distill liquid and medicinal residue for later use, and reflux extract kudzu root with 90% ethanol for 2 times, each time for 1.5 hours, filter, Combine the filtrate and steamed liquid for later use, add the dregs of kudzu root and bupleurum and other medicines to decoct for 1.5 hours, filter, combine the filtrate with the above solution, and decoct the remaining five medicinal materials with 6 times of water for 2 times, 1.5 hours each time , filtered, the filtrate was combined with the above solution, the combined solution was concentrated under re...

example 2

[0041] Example 2: Preparation of Granules

[0042] Recipe: Honeysuckle 300g, Pueraria 450g, Scutellaria baicalensis 300g, Banlangen 300g, Bupleurum 300g, Forsythia 300g, Guanzhong 250g, Angelica dahurica 150g, Campanulaceae 150g, Mannitol 500-600g, Lactose 200g, Aspartame 3g

[0043] Extract and volatile oil are made according to Example 1, after extract is mixed with mannitol, lactose and aspartame, add 75% ethanol and pass through 12 mesh sieves to make granules, after decompression drying, spray into volatile oil, each bag Packed in 10g. Make every bag contain crude drug to be 25g.

example 3

[0044] Example 3: Preparation of Tablets

[0045] Formula: 300g of honeysuckle, 450g of kudzu root, 300g of baicalin, 300g of Radix Radix, 300g of Bupleurum, 300g of Forsythia, 250g of Guanzhong, 150g of Angelica dahurica, 150g of bellflower, 70-130g of starch, 50g of microcrystalline cellulose, 20g of sodium carboxymethyl starch, Magnesium stearate 3g

[0046] Make extract and volatile oil according to Example 1, mix extract with starch and microcrystalline cellulose, add 75% ethanol to pass through a 20 mesh sieve to make granules, dry under reduced pressure, spray volatile oil, and then add disintegrant After sodium carboxymethyl starch and glidant magnesium stearate are mixed uniformly, the tablet is pressed so that the tablet weight is 0.5g / tablet, and the crude drug content is 3.125g.

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PUM

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Abstract

The invention relates to a traditional Chinese medicine compound preparation for treating cold, influenza and upper respiratory tract infection and a preparation method thereof. The traditional Chinese medicine compound preparation comprises the following active ingredients in percentage by weight: 10 to 15 percent of honeysuckle, 15 to 20 percent of radix puerariae, 10 to 15 percent of baikal skullcap root, 10 to 15 percent of radix isatidis, 10 to 15 percent of radix bupleuri, 10 to 15 percent of forsythia, 8 to 12 percent of cyrtomium fortunei, 5 to 8 percent of angelica dahurica and 5 to 8 percent of balloon flower. The preparation is in forms of granules, capsules, tablets and the like, has the functions of dispelling pathogenic wind from muscles, clearing away heat and toxic materials and relieving sore throat and a cough, and mainly treats symptoms such as fever, typhoid, body pain, snuffles, nose running, dry throat, pharyngalgia, cough, skin eruption, swelling and ulcer and the like caused by affection of exogenous wind-heat, cold and lung and stomach heat. The traditional Chinese medicine compound preparation has obvious treatment effect, fewer side effects, no damages to the liver and the kidney, and fragrant and sweet taste, children like to take the preparation and the preparation can be applied to the treatment of virus infection and the bacterial infection of children.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method, in particular to an antibacterial and antiviral traditional Chinese medicine compound preparation and a preparation method. Background technique [0002] Influenza is an acute respiratory infectious disease caused by influenza virus. In history, there have been many worldwide influenza pandemics, among which the influenza epidemic in 1918 was the most serious, and its death toll reached more than 20 million, and most of the deaths were young adults aged 15-45. At present, the threat of influenza still exists. In early 2009, H1N1 influenza was discovered in South America and has spread to five continents around the world. As of July last year, a total of 2,003 confirmed cases of H1N1 influenza have been reported in mainland my country, and there is an increasing trend. WHO started the influenza program as early as 1948, and has established 111 national resear...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/634A61P11/00A61P31/00A61P31/16
CPCY02A50/30
Inventor 张宇鹏刘世荣盘君辉
Owner WUHAN LANGJI PHARMA IND
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