413 results about "Venenum bufonis" patented technology

The invention discloses an anti-tumor traditional Chinese medicine comprising medicinal materials such as astragalus mongholicus, American ginseng, angelica sinensis, sculellaria barbata, oldenlandia diffusa, bighead atractylodes rhizome, endothelium corneum gigeriae galli, grifola, paris polyphylla, Indian strawberry, radix ranunculi ternati, radix curcumae, honey-fried licorice root, scorpion, venenum bufonis and the like. All the medicines supplement each other so that the absorption and operation of the medicines are accelerated and all the medicines are prevented from being cool; and the anti-tumor traditional Chinese medicine has the effects of tonifying Qi of spleens and lungs, tonifying the spleen and promoting dampness, dissolving phlegm, softening hard mass, breaking Qi, clearing away heat and toxic materials, and promoting blood circulation and stopping pain; with regard to patients with a peed tumor and better physique, pseudo-ginseng, leech, the venenum bufonis and the whole scorpion can be added into the medicine to realize the aims of combating poison with poison and enhancing the effect, so as to realize the anti-cancer aim; and the anti-tumor traditional Chinese medicine continually has a better treating effect on the treatment of the tumor.

The invention discloses a novel traditional Chinese medicine composition for treating toothache and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following raw medicines: pricklyash peel, clove, storax, venenum bufonis, borneol, camphor, grassleaf sweetflag rhizome, cornu saigae tatariace powder, tall gastrodia tuber, the larva of silkworm with botrytis, nidus vespae, catechu, dragon blood, unbracteolated spurge root, Chinese eaglewood wood, rosewood, rhubarb, officinal magnolia bark, villous amomum fruit, atractylodes rhizome, fineleaf schizonepeta herb, divaricate saposhnikovia root, frankincense and myrrh. The traditional Chinese medicine composition can be prepared into any one commonly used oral preparation according to the conventional method of traditional Chinese medicine preparations. The invention can obviously improve the symptoms of toothache, gingival swelling, pain in case of hot and cold stimulation, cheek swelling and the like, and has obvious clinical curative effect, significant curative effect and rapid effect. Since the traditional Chinese medicine composition adopts medicinal and edible medicines stipulated in the Chinese Pharmacopoeia to compound, the composition has the advantages of low cost, basically non-toxic side effects and the like.

The invention discloses a traditional Chinese medicine externally-applied anaesthetic comprising radix notoginseng, zanthoxylum, tianwencao, raw southern star, liangmianzhen, Indian stringbush, raw kusnezoff monkshood, murraya jasminorage, wild ginger, venenum bufonis and borneol. The medicine not only has an anesthetization function but also has the functions of decreasing swelling, alleviating pain, resisting bacteria, diminishing inflammation, disinfecting and sterilizing. The invention has simple operation, safety, reliability, lasting medicine effect, obvious curative effect and no irritation.

The invention discloses a herbal anesthetic which is prepared from the following raw materials in parts by weight: 13-15 parts of venenum bufonis, 8-13 parts of raw szechuan aconite, 7-13 parts of raw wild aconite, 20-25 parts of pepper, 16-20 parts of asarum, 15-18 parts of radix zanthoxyli, 7-10 parts of borneol, 20-30 parts of murraya jasminorage, 4-6 parts of houttuynia, 2-4 parts of gallnut, 6-8 parts of Chinese mugwort leaf, 4-6 parts of bistorta, 4-6 parts of dandelion, 4-6 parts of brucea javanica, 100-130 parts of notoginseng and 600-700 parts of alcohol the concentration of which is 75%. The herbal anesthetic disclosed by the invention is convenient to use and simple to operate, has the advantages of good anesthetic effect, no side effects, safety, reliability and the like, eliminates the pain of patients in the processes of extracting and treating teeth, eliminates the fear of patients, is popular among patients, especially enables the deciduous teeth of children to be replaced painlessly, conveniently and quickly, lowers the allergic probability, reduces the postoperative hemorrhage, and prevents the infection.

A traditional Chinese medicine preparation for treating osteopathia comprises two groups of composing prescriptions, namely, the first group is as follows: a medicinal plaster A is prepared by centipede, scorpion, bungarus parvus, zaocys dhumnade, lumbricus, pangolin scales, ground beeltle, honeybee, black ants, moschus and venenum bufonis; the second group is as follows: a medicinal plaster B is prepared by semen strychni, aconitum brachypodum, flos daturae, radix aconiti, cortex cinnamomi, radix aconiti carmichaeli, panax notoginseng, ligusticum chuanxiong, radix dipsaci, radix cyathulae, fructus psoraleae, borneol, rhizoma homalomenae, radix clematidis, herba ephedra, herba asari cum radice, rhizoma sparganii, rhizoma curcumae, angelica sinensis, flos carthami, radix angelicae pubescentis, honeycomb, cortex eucommiae and semen momordicae. The medicinal plaster A and the medicinal plaster B are alternately applied while the two plasters are utilized. The traditional Chinese medicine preparation can also be prepared into various doses of medicinal plasters, ointments and externally-applied medicinal oils, and can be brewed into the medicinal liquor after being slightly adjusted or decocted to a decoction for oral administration. The invention has the following beneficial effects: the traditional Chinese medicine preparation is utilized to treat the diseases, such as osteoproliferation, osteoarthritis and degenerative osteoarthritis, and has the characteristics of being remarkable in efficacy, stable in effect, long in storage period, unlikely to relapse, flexible to prepare, convenient to use and taking effect quickly.

The invention discloses an external-use ointment for treating hemorrhoids, comprising the following components: notopterygium root, lightyellow sophora root, angelica dahurica, borneol, airpotato yam rhizome, lithospermum, wild chrysanthemum, dandelion, ficus virens, herba schizonepetae, linseed oil, scorpion, venenum bufonis, safflower, panax notoginseng, gallnut, pepper, radix saposhnikoviae, cimicifuga foetida, Chinese thorowax, rhizoma atractylodis and vaseline. The product provided by the invention has the effects of clearing heat and cooling blood, relieving toxin and removing dampness, relaxing bowel and relieving constipation, astringing, diminishing inflammation and relieving pain, can eliminate fester, relieve toxin and promote granulation when being applied to an affected part, has the advantages of good effect, short treatment course, no pain, obvious effect on treating various types of hemorrhoids, low cost, wide sources in raw materials, simpleness in manufacturing, convenience for using, rapidity in relieving pain and itch and rapid recovery, needs no any facility in treatment process and is low in price and convenient for application and popularization.

The invention discloses a traditional Chinese medicine for preventing and curing chicken respiratory diseases, which is prepared from the following raw materials: 2-10g of ephedra, 3-10g of semen armeniacae amarae, 3-10g of liquorice, 15-60g of gypsum, 10-15g of chrysanthemum, 5-10g of folium mori, 6-15g of fructus forsythiae, 3-6g of mint, 3-10g of Platycodon grandiflorum, 10-15g of honeysuckle, 10-30g of dandelion, 15-30g of Houttuynia cordata, 10-15g of folium isatidis, 3-10g of Scutellaria baicalensis, 10-15g of Radix Ophiopogonis and 0.015-0.03g of venenum bufonis. The invention adopts pure traditional Chinese medicine preparation, has the functions of diminishing inflammation, sterilizing and relieving cough and asthma, and has good prevention and cure effect on chicken respiratory diseases.

The invention discloses an ecological method for mixed cultivation of river crabs and toads in a rice field. The method is characterized by comprising the following steps of: selection and arrangementof the rice field; establishment of an escape-proof net; cultivation and management of rice; treatment of aquaculture ditches; arrangement of organic matter on an inhabiting platform; releasing of toads and river crabs and arrangement of moth-killing lamps; by means of the technical scheme, through the arrangement of the escape-proof net, escaping of the river crabs and toads is avoided; throughthe arrangement of the aquaculture ditches and the inhabiting platform in the rice field, snails and earthworms are propagated; through the arrangement of the moth-killing lamps, abundant natural feedsources are provided for the river crabs and toads, and therefore the produced river crabs are natural and good in quality; in addition, it is convenient to catch the toads and collect venenum bufonis, and the problem of pest control is solved; the rice in the rice field has a good ecological status, and the produced rice has good quality; the ecological method for mixed cultivation of the rivercrabs and toads in the rice field is beneficial to production and operation, practical and convenient and has good benefits.

The invention discloses a medicament for clinical anesthesia and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The medicament disclosed by the invention comprises the following effective components: venenum bufonis, caulis spatholobi, ostrokrzew kolczasty, musk, camphor, lycopodium clavatum, radix euphorbiae lantu, borneol, flos daturae, radix angelicae, fructus piperis longi, lalang grass rhizome, pepper, rhizoma arisaematis, coriaria sinica and circium japonicum. The medicament disclosed by the invention is prepared from selected excellent medicinal materials by adopting the modern advanced pharmaceutical technology, has a significant effect on anesthesia of a nervous system, and is applicable to anesthesia of local organisms and skin epidermis in an operation process. Clinical application proves that the medicament gas a significant effect and is safe and free of toxic and side effects, and worthy of clinical wide popularization and application.

The invention relates to a traditional Chinese medicine venenum bufonis extract. A method for extracting the extract includes steps of extracting traditional Chinese venenum bufonis medical materials at the temperature ranging from 60 DEG C to 90 DEG C by ethanol water with volume percent of 60-95% in a backflow manner, separating extract liquid via silicagel columns after the extract liquid is concentrated, adopting petroleum ether and acetone with volume ratio of 1-8:1 as eluant to realize gradient elution, collecting parts of eluent, and filtering, concentrating and drying the eluent in a pressure reduction manner to obtain the traditional Chinese medicine vanenum bufonis extract containing mixture of three types of bufotalin including resibufogenin, cinobufagin and bufalin, wherein the sum of the weight percentages (calculated when three types of the bufotalin are dried) of the three types of the bufotalin is higher than or equal to 95%. The invention further provides the preparation method for the traditional Chinese medicine venenum bufonis extract. The sum of the weight percentages of the three types of the bufotalin in the traditional Chinese medicine venenum bufonis extract is higher than 95%, extraction transfer rate is high, the quantity of used solvent is lower, residual solvent is little, pollution degree is lower, operation is simple and convenient, and industrial production is realized easily.

The invention discloses an anti-tumor Chinese medicine composition and a preparation method and application thereof. The Chinese medicine composition is prepared with the following raw materials in parts by weight: 10-100 parts of ligusticum wallichii, 10-200 parts of corydalis amabilis, 1-50 part(s) of prepared monkshood, 10-300 parts of daphne giraldii nitsche, 10-100 parts of gentiana macrophylla and 1-50 part(s) of venenum bufonis. The traditional Chinese medicine composition provided by the invention is prepared according to the formula of the traditional Chinese medicine based on the theory of the traditional Chinese medicine and the theory of syndrome differentiation and treatment, and the results of in vivo and in vitro experiments show that the traditional Chinese medicine composition provided by the invention has the functions of inhibiting the growth of the tumor cell and promoting the apoptosis of the tumor cell, and has a strong function of killing a variety of tumor cells. Therefore, the scope of application of the traditional Chinese medicine composition is wide. Moreover, the extract of the traditional Chinese medicine composition provided by the invention can be prepared as various preparations, can be taken conveniently in clinical treatment and has no toxic and side effect in the long-term use.

The invention relates to a herbal anesthetic, which comprises Venenum Bufonis, unprocessed Radix aconiti, rhizoma arisaematis, unprocessed Radix Aconiti Kusnezoffii, unprocessed Semen Strychni, unprocessed Rhizoma Pinelliae, stellera chamaejasme, Bungarus Parvus, borneol, asarum, dandelion, mint, Zanthoxylum nitidum, Liaoxiang, Murraya paniculata, Lycopodii herb, asarum, and suberect spatholobus stem. Being prepared from traditional Chinese medicines, the herbal anesthetic provided by the invention has fast anesthetic action and small side effect, can be used for superficial operations and general anesthesia, and can be used for implementing deep operations after taking an increased dosage according to operation requirements.

The invention discloses a new Chinese herbal composite for deafness treatment and a preparation method thereof. The Chinese herbal composite of the invention is mainly prepared by the following ingredients of cortex phellodendri, musk, styrax, benzoin, venenum bufonis, camphor, borneol, raw milkvetch root, malaytea scurfpea fruit, fructus alpiniae oxyphyllae, eucommia bark, radix paeoniae alba, manyflower solomonseal rhizome, radix angelicae sinensis, fritillary, ground beetle, white bombyx batryticatus, dragon's blood resin, rhizoma drynariae, rhizoma sparganii, rhizoma curcumae, dragon's blood resin, catechu, squama manitis and the like. The Chinese herbal composite of the invention can be prepared into any common oral preparation according to the conventional Chinese medicine preparation method. The medicine can obviously improve conductive deafness resulting from pathologic change of the external ear and the middle ear, and nerve deafness resulting from pathologic change of the internal ear and the auditory nerve, and has reliable and apparent clinical effect and fast desired effect. The Chinese herbal composite of the invention also has the advantages of low cost, basically no toxic or side effect and the like.

Belonging to the field of traditional Chinese medicines, the invention particularly relates to a Chinese medicinal composition treating a duck Tembusu virus. The Chinese medicinal composition is prepared from the following raw materials by weight: 45g of Schizonepeta, 30g of radix sileris, 25g of notopterygium roots, 25g of radix angelicae biseratae, 30g of radix bupleuri, 25g of Radix Peucedani, 30g of fructus aurantii, 45g of Poria cocos, 30g of Platycodon grandiflorum, 25g of Ligusticum wallichii, 15g of liquorice, 15g of mint, 30-50g of Venenum Bufonis, 40-80g of radix isatidis, 50-100g of folium artemisiae argyi, 30-50g of Polygonum multiflorum, 40-80g of hawthorn, and 40-80g of dried tangerine peel. The Chinese medicinal composition provided in the invention has very good efficacy on poultry egg laying decrease, inappetence, depression and diarrhea caused by the duck Tembusu virus, an influenza virus and an egg drop syndrome virus, and especially has significant efficacy on sudden egg drop syndrome caused by duck Tembusu virus infection.

The invention relates to medicines, and in particular relates to a traditional Chinese medicine paste for treating cancer pain, which can used for effectively solving the problems of the existing medicine which is small in therapeutical effect and large in side effect. According to the technical scheme, the traditional Chinese medicine paste is prepared from the following raw medicinal materials: 2g to 5g of musk, 5g to 10g of calculus bovis, 15g to 30g of borneol, 20g to 40g of common monkshood mother root, 15g to 50g of radix aconiti agrestis, 5g to 15g of nux vomica, 60g to 100g of bamboo flower, 10g to 40g of ferula asafoetida, 20g to 50g of zedoary, 15g to 35g of notoginseng, 30g to 60g of edible tulip, 30g to 65g of radices trichosanthis, 20g to 55g of raw frankincense, 20g to 55g of raw myrrh, 30g to 60g of spina gleditsiae, 15g to 45g of thunberg fritillary bulb and 2g to 4g of venenum bufonis. The traditional Chinese medicine paste is suitable for the treatment of pains caused by various cancers, can be used for obviously relieving pain symptoms and has the functions of eliminating tumescence, removing stasis and reducing lump. The traditional Chinese medicine paste has a definite effect and a good application effect. Thus, the traditional Chinese medicine paste is a novel medicine used for treating the cancer pain.

The invention relates to a traditional Chinese medicine composite for treating a respiratory disease and a preparation method thereof. The traditional Chinese medicine composite comprises the following components in percentage by weight: 15%-25% of flos daturae, 4%-8% of ephedra herbs, 5%-15% of bitter almonds, 5%-15% of venenum bufonis, 3%-9% of borneols, 10%-30% of radix isatidis, 10%-20% of liquorices and 10%-20% of plasters. The preparation method of the traditional Chinese medicine composite comprises the following steps of: (1) respectively weighing the flos daturae, the ephedra herbs, the bitter almonds, the venenum bufonis, the borneols, the radix isatidis, the liquorices and the plasters according to the percentage by weight, all grinding into powder, and respectively completely sieving through a sieve of 80 meshes; (2) placing the flos daturae, the ephedra herbs, the bitter almonds, the venenum bufonis, the borneols, the radix isatidis, the liquorices and the plasters which are sieved in the step (1) into a mixing tank, and sufficiently uniformly mixing. The invention has the effects of relieving cough and asthma and easing pains, is convenient to use, has lower cost and has no toxic and side effect or medicine residues or medicine tolerance.

The invention relates to traditional Chinese medicine powder, in particular to traditional Chinese medicine powder for treating pig high fever and a preparation process of the powder. The traditional Chinese medicine powder comprises the following raw materials in percentage by weight: 5%-9% of astragalus membranaceus, 5%-9% of honeysuckle, 4%-8% of wild chrysanthemum flowers, 1%-4% of venenum bufonis, 8%-12% of isatis root, 6%-10% of houttuynia cordata, 4%-8% of sculellaria barbata, 3%-7% of bighead atractylodes rhizome, 3%-7% of divaricate saposhnikovia root, 5%-10% of raw gypsum, 4%-8% of cape jasmine, 5%-9% of fructus forsythiae, 5%-9% of scutellaria baicalensis, 5%-9% of polygonum cuspidatum, 3%-7% of pulsatilla root and 2%-6% of radix sophorae flavescentis. The powder is mainly used for treating various viral diseases, and has a very good effect on the pig high fever.

The invention relates to the field of traditional Chinese medicines, and in particular relates to a Chinese medicine composition and a preparation method and an application thereof. The Chinese medicine composition is prepared from the following raw materials in parts by weight: 750 parts of Astragalus membranaceus, 500 parts of curcuma zedoary, 250 parts of Peganum harmala, 62.5 parts of Poria cocos, 2.5 parts of venenum bufonis, 125 parts of Rabdosia rubescens and 250 parts of radix bupleurim. According to the composition, a prescription of traditional body-strengthening and stasis-removing decoction is adjusted, and the use level of medicinal materials is reduced. The novel preparation method is adopted to respectively extract different medicines by different manners in allusion to effective components in the medicine, so that the transfer rate of effective substances is ensured. The Chinese medicine composition can be used for preparing medicines for treating advanced liver cancer, and the dosage form is free from a long time decocting process before administration as the traditional body-strengthening and stasis-removing decoction is to be decocted. The composition is accurate in dosage, convenient to store and stable in property, the patient is convenient to take the composition, and unnecessary pain caused by bad taste of the traditional decoction to the patient is further avoided.

The invention relates to a traditional Chinese medicine prescription for treating Newcastle disease and avian influenza. The traditional Chinese medicine prescription is composed of rhizoma coptidis, skullcap, phellodendron bark, gentian root, honeysuckle, forsythia, herba violae, dandelion, bupleurum, cimicifugae foetidae, stephanotis, dangshen, pseudostellaria heterophylla, astragalus, bighead atractylodes rhizome, angelica, epimedium, rhizoma polygonati, venenum bufonis, aster, flos farfarae, platycodon grandiflorum and licorice. The traditional Chinese medicine prescription has an obvious curative effect on Newcastle disease and avian influenza.

The invention discloses a medicine for treating cancer and a preparation method thereof. The medicine is prepared by compatibility of 37 traditional Chinese medicines, such as sulphur, venenum bufonis extractive, crude lateral root of aconite and pedate pinallia jackinthepulpit rhizome. The preparation method comprises the following steps of: smashing 15 medicines of sulphur, venenum bufonis extractive and the like into fine powder; then, adding water to decoct 22 medicines of crude lateral root of aconite, pedate pinallia jackinthepulpit rhizome and the like; condensing decoction into thick paste; and finally evenly mixing the above medicine powder and the thick paste with rice vinegar to obtain the medicine. The medicine has the advantages of scientific and novel medicine prescription, and reasonable compatibility of medicines of assistant and guide, has obvious efficacy on cultivating the Yuan, strengthening the body resistance, activating blood, dredging collaterals, counteracting toxic substances, eliminating stagnation, inhibiting cancer and eliminating tumors, can be singly taken and also can also be cooperated with the surgery, radiotherapy and chemotherapy.

The invention relates to a drug prescription for treating cancer and belongs to the technical field of a drug prescription. The drug prescription comprises the following components by weight: 20-30g of oldenlandia diffusa, 10-15g of sculellaria barbata, 9-15g of radix semiaquilegiae, 5-10g of red paeony root, 6-10g of szechuan lovage rhizome, 10-15g of zedoary turmeric oil, 10-15g of grifola, 10-15g of astragalus root, 15-30g of honeysuckle flower, 3-10g of thunberg fritillary bulb, 10-20g of paris polyphylla, 10-20g of Chinese lobelia herb, 10-15g of Salvia miltiorrhiza, 6-9g of rhizoma alismatis, 10-20g of rhizoma sparganii, 3-12g of Chinese angelica, 10-15g of atractylis ovata, 8-10g of poria cocos, 2-4g of indigo naturalis, 3-6g of liquorice, 1-6g of venenum bufonis and 1-6g of leeches as well as 1-3 centipedes. The drug prescription can be used for treatment based on syndrome differentiation, effectively control the cancer cell expansion and block the cancer cell growth, thereby gradually killing cancer cells and achieving good treatment effect.

The invention discloses an external medicine nose through paste for treating rhinitis and a preparation method thereof. The nose through paste comprises the following main raw materials in percentage by weight: 8.0%-9.4% of asarum, 23.2%-28% of Chinese honeylocust fruits, 8.7%-9.4% of borneol, 8.7%-9.4% menthol, 5.6%-7.2% of raw calculus bovis, 0,4%-0.45% of musk, 0.40%-0.45% of venenum bufonis powder and 37.4%-43.4% of cape jasmine. The preparation method comprises the following steps of: carefully selecting substances with impurities removed; grinding into fine powder, screening at 80-100 meshes; hermetically soaking for 72 hours by adopting 45-degree edible white spirit which is 1.5 times of the main raw materials and using a porcelain jar; and extracting juice for usage; uniformly blending into a paste by adopting medical vaseline which is 1.5 times of the main raw materials so as to prepare the nose through paste. The nose through paste disclosed by the invention is an external paste medicine used for treating the rhinitis, is used without toxic side effect or recrudescence and has the advantages of lower cost, convenience for application, simple preparation method and wide application value.

The invention discloses a traditional Chinese medicine tincture for treating neck-shoulder and waist-leg pain. The traditional Chinese medicine tincture comprises garden balsam stems, cortex illicii, suberect spatholobus stems, radix aconiti lateralis preparata, cinnamon, pericarpium zanthoxyli, ovientvine, kadsura pepper stems, rhizoma dioscoreae nipponicae, radix clematidis, cortex erythrinae, tripterygium wilfordii, semen strychni, rhizoma drynariae, dragon blood, hematoxylon, notopterygium roots, radix angelicae tuhuo, asarum, cassia twigs, radix paeoniae rubra, polygonum cuspidatum, stephania tetrandra, pberetima, red flowers, peach kernel, radix aconiti preparata, radix aconiti agrestis, lycopodium clavatum, corydalis tuber, rhizome of chuanxiong, scorpio, frankincense, myrrh, excrementum pteropi, cattail pollen, caulis lonicerae, dipsacus asperoides, rhizoma cibotii, licorice, venenum bufonis, musk and rice vinegar. The medicines are combined, effects of the medicines are synergistic, so that the tincture has the functions of effectively expelling wind, removing cold, relaxing tendons, activating collaterals, warming meridians, removing moisture, promoting blood circulation, removing blood stasis, diminishing swelling and relieving pain, medicine compatibility meets traditional Chinese medicine theories and requirements of Chinese pharmacopoeia, and the tincture has no toxic and side effects on human bodies.

The invention discloses a new application of venenum bufonis polypeptide as medicine penetration enhancers, including bufadienolide and the like. An in vitro Franz diffusion cell and an in vivo transdermal experiment test the penetration enhancement effect of the venenum bufonis polypeptide on the bufadienolide. An LC-MS / MS (Liquid Chromatogram-Mass Spectrometry / Mass Spectrometry) method carries out detection to discover that the penetration of six types of main bufadienolide in cavia procellus skins is increased by 36.99-91.13% after the venenum bufonis polypeptide is added. A von Frey filament stimulation method verifies that the venenum bufonis polypeptide can improve the anti-inflammatory and analgesic capability of the bufadienolide. After the venenum bufonis polypeptide is applied, 2% formalin is injected on the right rear foot of the cavia procellus, a test result indicates that the mechanical withdrawal threshold of the right rear foot of the cavia procellus added with the bufadienolide of the venenum bufonis polypeptide is obviously improved, and the mechanical withdrawal threshold is improved by 2-3 times after the formalin is injected for 30min. The venenum bufonis polypeptide can accelerate the penetration of sterene in the skin of the cavia procellus so as to enhance the anti-inflammatory and analgesic effect of the venenum bufonis polypeptide.

The invention relates to antitumor drugs and discloses anti-glioma drugs based on Venenum Bufonis extract and a preparation method thereof, the drugs being a bufotalin submicron emulsion and a bufotalin nanoparticle preparation, wherein the bufotalin submicron emulsion comprises Venenum Bufonis extract, medium chain triglyceride, a lecithin, poloxamer 188, glycerol, sodium oleate and injection water; the bufotalin nanoparticle preparation comprises Venenum Bufonis extract, glycerol monostearate, medium-chain fatty acid glyceride, oleic acid, a lecithin, poloxamer 188, sodium deoxycholate and injection water. Both the two preparations can combine with endothelial cells in cerebral blood capillaries, enabling the drugs to be transmitted into the brain through membranes or by means of adsorption, medication, endocytosis and transferring, cerebral targeting of the drugs is improved, and further increase of bufotalin in the brain is facilitated, and glioma resistance is achieved by inducing apoptosis and excessive autophagy of cells.

The invention relates to a traditional Chinese medicine for treating pig blue-ear disease. The traditional Chinese medicine is characterized by containing the following materials in parts by weight: 0.4-0.6 part of rhinoceros horn, 4-6 parts of Radix Rehmanniae, 4-6 parts of Radix Ophiopogonis, 4-6 parts of Radix Scrophulariae, 3-5 parts of indigowoad leaf, 3-5 parts of forsythia, 6-10 parts of dandelion, 6-10 parts of honeysuckle flower, 4-6 parts of Radix Sophorae Subprostratae, 4-6 parts of rhizoma belamcandae, 4-6 parts of platycodon root, 3-5 parts of Rhubarb, 3-5 parts of Radix Paeoniae Rubra, 2-4 parts of glycyrrhiza and 0.3-0.5 part of venenum Bufonis. A preparation method of the traditional Chinese medicine comprises the steps of taking the pure natural Chinese herbs as materials, processing, crushing and grinding the materials into fine powder, drying and sterilizing the fine powder, adding related carriers and catalysts, and conducting subpackaging. Aiming at clinical symptoms of the pig blue-ear disease, the traditional Chinese medicine is prepared from numerous pure natural Chinese herbs for clearing away heat and toxic materials, cooling blood and reliving startle, thus having good treatment effects, no drug residue and no environment pollution.

The invention belongs to the technical field of traditional Chinese medicine anesthetics, and particularly relates to a multi-effect local anesthetic. The anesthetic is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 5-8 parts of venenum bufonis, 5-15 parts of flos daturae, 5-15 parts of semen hyoscyami, 5-10 parts of passionflower, 5-8 parts of pepper, 3-6 parts of radix aconiti kusenzoffii, 5-8 parts of pedate pinallia jackinthepulpit rhizome, 5-8 parts of unprocessed rhizoma pinelliae, 3-6 parts of long pepper, 3-6 parts of asarum, 3-6 parts of frankincense, 3-6 parts of myrrh, 3-6 parts of clove, 3-6 parts of cinnamon, 3-6 parts of radix angelicae, 3-6 parts of rhizoma arisaematis and 3-6 parts of marmor serpentinatum. The anesthetic is prepared into dressing according to a preparation method, and is used for binding an operative incision by using local anesthetic fibers. According to the local anesthetic, the effects of anesthetic, pain, spasm and convulsions relieving of traditional Chinese medicinal materials are combined with effects of drawing out toxins, promoting granulation, eliminating blood stasis and relieving pain, so that multiple effects that the local anesthetic can be used for quickly infiltrating for sedation and analgesia before an operation, reducing injection dosage of local anesthetic, continuously performing anesthetic and analgesia and promoting incision healing after the operation, and the like can be achieved.

The invention relates to a plaster for curing cervical spondylosis, which consists of ginger, centipede, manis pentadactyla, stiff silkworm, radix clematidis, cistanche, prepared rehmannia root, caulis sinomenii the root of red-rooted salvia, venenum bufonis and astragalus mongholicus, wherein the weight ratio is as follows: 10-15 parts of the ginger, 3-5 parts of the centipede, 4-6 parts of the manis pentadactyla, 3-5 parts of the stiff silkworm, 3-5 parts of the radix clematidis, 3-5 parts of the cistanche, 4-7 parts of the prepared rehmannia root, 3-5 parts of the caulis sinomenii, 4-6 parts of the root of red-rooted salvia, 3-5 parts of the venenum bufonis and 5-8 parts of the astragalus mongholicus. The preparation method comprises the steps of smashing the ginger, the centipede, the manis pentadactyla, the stiff silkworm, the radix clematidis, the cistanche, the prepared rehmannia root, the caulis sinomenii the root of red-rooted salvia, the venenum bufonis and the astragalus mongholicus into powder; adding the powder into a substrate of the plaster; coating on the surface of a non-woven fabric; and drying. The plaster is pasted on wounded parts to stop pain within 20 minutes and simultaneously have the functions of dispelling the cold, relaxing the muscles, and stimulating the blood circulation. The plaster has special prescription and high cure rate, is Chinese medical preparation, and has no side effect, low recurrence rate, convenient application, simple preparation method and low preparation cost. The plaster has a remarkable effect for curing the cervical spondylosis in clinically.

The invention relates to a feed for increasing laying hen fertilization rate and laying rate, which comprises a feed main material and a traditional Chinese medicine additive, wherein the main material comprises the following raw materials by weight: 50-60 parts of corn, 25-30 parts of soybean meal, 4-6 parts of fish meal, 5-7 parts of wheat bran, 4-6 parts of shell powder, 2-3 parts of bone meal, 3-5 parts of trace elements, 3 parts of compound vitamin, and 2 parts of lysine; the weight part of the traditional Chinese medicine additive is 1, and the traditional Chinese medicine additive comprises isatis roots, radix astragali, epimeddium, venenum bufonis, bezoar, borneol, gypsum, glutinous rehmannia, buffalo horn, coptis, fructus forsythia, and balloonflower roots. The feed is not only added with trace elements such as nitrogen, phosphorus, calcium and the like, but also added with trace of pyridoxine algae on the basis of general feed; pyridoxine has promotion effect on internal protein digestion and absorption of laying hens, so absorption of amino acids by laying hens is promoted, and thus disease resistance of laying hens is improved; during feeding, the rates of diseased hens and dead hens are decreased by 50% and 80% respectively.

The invention relates to a Chinese herbal preparation for treating rectum carcinoma. The preparation comprises the following active pharmaceutical ingredients in parts by weight: 8.95-9.05 parts of cordyceps, 0.03-0.08 part of venenum bufonis, 14.95-15.05 parts of sophora flavescens, 9.95-10.5 parts of pseudobulbus cremastrae seu pleiones, 1.05-2.05 parts of brucea javanica, 11.05-12.05 parts of lithospermum purpurocaeruleum, 49.95-50.05 parts of hedyotis diffusa, 49.95-50.05 parts of scutellaria barbata, 19.95-20.05 parts of golden cypress, 0.25-0.35 part of realgar, 17.95-18.05 parts of mirabilite and 14.95-15.05 parts of liquorice. The Chinese herbal preparation is reasonable in formula, and moreover, the compatible Chinese herbal preparation does not have toxic and side effects, can gradually separate cancer tissues from rectum walls and discharge the cancer tissues out of the body, is simple in preparation method and low in production cost and has an obvious curative effect than conventional curative medicines; the Chinese herbal preparation has a wide treatment application scope, and can be used for treating patients with middle and later periods of cancer, advanced age, weakness or other diseases; and the Chinese herbal preparation has a good treatment effect and a high curative rate, and the survival rate of the operation patients after five years is 50%, and the survival rate of the patients after being treated by the Chinese herbal preparation in five years reaches above 70%.