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Compound gentamicin sulphate composition for treating poultry diarrhea and preparation method thereof

A technology of gentamicin sulfate and composition, which is applied in the direction of drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, which can solve unreasonable prescriptions, poor clinical effects, and easy drug resistance, etc. problem, to achieve the effect of less drug resistance, uniform mixing step by step, and remarkable curative effect

Inactive Publication Date: 2013-03-20
QINGDAO LVMAN BIOLOGICAL ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the most commonly used antibacterial products for the treatment of this disease are prone to drug resistance due to unreasonable prescriptions, resulting in poor clinical effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A compound gentamicin sulfate composition for treating poultry diarrhea and a preparation method thereof: proceed as follows: (each part is calculated as 10g)

[0022] (1) Take 50 parts of gentamicin sulfate, 100 parts of ciprofloxacin hydrochloride and 150 parts of anhydrous glucose by weight, mix for 5-10 minutes until uniform;

[0023] (2) Weigh 100 parts of berberine hydrochloride, 50 parts of trimethoprim lactate, and 150 parts of anhydrous glucose by weight, and mix for 5-10 minutes until uniform;

[0024] (3) Combine the mixture prepared in steps (1) and (2) above with the remaining anhydrous glucose, and continue mixing for 10-15 minutes until uniform.

Embodiment 2

[0026] A compound gentamicin sulfate composition for treating poultry diarrhea and a preparation method thereof: proceed as follows: (each part is calculated as 10g)

[0027] (1) Weigh 75 parts of gentamicin sulfate, 125 parts of ciprofloxacin hydrochloride and 200 parts of anhydrous glucose by weight, mix for 5-10 minutes until uniform;

[0028] (2) Weigh 150 parts of berberine hydrochloride, 70 parts of trimethoprim lactate, and 220 parts of anhydrous glucose by weight, and mix for 5-10 minutes until uniform;

[0029] (3) Combine the mixture prepared in steps (1) and (2) above with the remaining anhydrous glucose, and continue mixing for 10-15 minutes until uniform.

Embodiment 3

[0031] A compound gentamicin sulfate composition for treating poultry diarrhea and a preparation method thereof: proceed as follows: (each part is calculated as 10g)

[0032] (1) Weigh 100 parts of gentamicin sulfate, 150 parts of ciprofloxacin hydrochloride and 25 parts of anhydrous glucose by weight, mix for 5-10 minutes until uniform;

[0033] (2) Weigh 200 parts of berberine hydrochloride, 90 parts of trimethoprim lactate, and 290 parts of anhydrous glucose by weight, and mix for 5-10 minutes until uniform;

[0034] (3) Combine the mixture prepared in steps (1) and (2) above with the remaining anhydrous glucose, and continue mixing for 10-15 minutes until uniform.

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PUM

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Abstract

The invention relates to a compound gentamicin sulphate composition for treating poultry diarrhea. The compound gentamicin sulphate composition is characterized by being prepared by mixing the following components by weight part: 5-10 parts of gentamicin sulphate, 10-15 parts of ciprofloxacin, 10-20 parts of berberine hydrochloride, 5-9 parts of trimethoprim Lactate salt and 46-70 parts of glucosum anhydricum. The compound gentamicin sulphate composition has the beneficial effects of reasonable formula, simple preparation, extremely obvious curative effect and special effect on the treatment of poultry diarrhea through clinical proving.

Description

technical field [0001] The invention relates to a compound gentamicin sulfate composition for treating poultry diarrhea and a preparation method thereof, belonging to the field of animal medicine, in particular to a compound gentamicin sulfate composition specially used for treating poultry diarrhea and a preparation method thereof. Background technique [0002] Poultry diarrhea is a relatively serious disease mainly caused by pathogenic bacteria such as Escherichia coli and Salmonella. Long-term severe diarrhea can cause the poultry body to lose a large amount of water, salt and alkaline substances, resulting in varying degrees of dehydration, salt deficiency and acidosis, blood concentration, which affects the normal circulation of body fluids, and eventually causes heart failure and death . The younger the poultry age, the higher the incidence rate and the higher the mortality rate, generally between 10% and 40%. The disease can occur throughout the year and is one of t...

Claims

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Application Information

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IPC IPC(8): A61K31/7036A61K31/505A61K31/496A61K31/4375A61P1/12A61P31/04
Inventor 周庆福刘文利
Owner QINGDAO LVMAN BIOLOGICAL ENG
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