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Compound norfloxacin nicotinate soluble powder for animals, and preparation method thereof

A technology of norfloxacin nicotinate and soluble powder, which is applied in the field of medicine and can solve problems such as intractable diseases and bacterial resistance

Active Publication Date: 2014-01-01
BAODING JIZHONG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the practice of treating poultry and livestock infected with bacterial intestinal diseases, the problem of bacterial resistance is very serious, even to the point that it is difficult to treat the disease with a single antibacterial drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] To prepare 100 g of soluble powder, the raw materials used were: 10 g of norfloxacin nicotinate, 5 g of apramycin sulfate, 3 g of trimethoprim lactate, and 82 g of anhydrous glucose. The above components were accurately weighed. Raw materials with large particles are crushed first; then, the above components are passed through a 40-mesh sieve. Premix norfloxacin nicotinate, apramycin sulfate, trimethoprim lactate and part of anhydrous glucose for 15 minutes, then add the remaining anhydrous glucose into the premix, and then fully Mixing, the mixing time is 20min, after mixing evenly, the veterinary compound norfloxacin niacin soluble powder is obtained.

Embodiment 2

[0018] Prepare 100 g of soluble powder, the raw materials used are: norfloxacin nicotinate 10 g, apramycin sulfate 10 g, trimethoprim lactate 4 g, anhydrous glucose 76 g, accurately weigh the above components, pass through a 40-mesh sieve respectively, and Raw materials with large particles are first crushed and then sieved; pre-mix norfloxacin nicotinate, apramycin sulfate, trimethoprim lactate and part of anhydrous glucose, and mix while adding. The mixing time is 18 minutes , and then add the remaining anhydrous glucose into the premixture, and then fully mix, the mixing time is 25min, after mixing evenly, the veterinary compound norfloxacin niacin soluble powder is obtained.

Embodiment 3

[0020] Prepare soluble powder 100g, raw materials used are: norfloxacin nicotinic acid 5g, apramycin sulfate 8g, trimethoprim lactate 4g, anhydrous glucose 83g, accurately weigh the above components, pass through a 40 mesh sieve respectively, and Raw materials with large particles are first crushed and then sieved; pre-mix norfloxacin nicotinate, apramycin sulfate, trimethoprim lactate and part of anhydrous glucose, and mix while adding. The mixing time is 20min , and then add the remaining anhydrous glucose into the premixture, and then fully mix, the mixing time is 30min, after mixing evenly, the veterinary compound norfloxacin niacin soluble powder is obtained.

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PUM

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Abstract

The invention relates to a compound norfloxacin nicotinate soluble powder for animals. A formula of 100g of the powder comprises 5-10g of norfloxacin nicotinate, 5-10g of apramyein sulfate, 2-4g of trimethoprim lactate, and the balance anhydrous glucose. The above medicine can rapidly kill intestinal pathogenic microorganisms to timely effectively control intestinal bacterial diseases of the animals, and alleviates the bacterial drug resistance.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to a veterinary compound soluble powder and a preparation method thereof. Background technique [0002] With the development of large-scale breeding, the health and normal function of poultry and livestock are of great significance to livestock and poultry production. It is the core issue of livestock and poultry production and a necessary condition for successful breeding. However, with the increase of pathogenic factors including feed, drinking water, management, bacteria, viruses, parasites, etc., bacterial intestinal diseases in animals are becoming more and more common. In the practice of treating poultry and livestock infected with bacterial intestinal diseases, the problem of bacterial drug resistance is very serious, even to the extent that it is difficult to treat the disease with a single antibacterial drug. Therefore, there is an urgent need for effective drugs, which c...

Claims

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Application Information

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IPC IPC(8): A61K31/7036A61K9/14A61P31/04A61P1/00A61K31/496A61K31/505
Inventor 邵谱韩旭东王宏伟吴里明
Owner BAODING JIZHONG PHARMA
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