647 results about "Pressure.drive" patented technology

The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.

An integrated treatment system using electrodialysis and pressure-driven membranes for deionizing and decontaminating liquids to a near-pure quality for use or reuse in industrial or municipal operations. The integrated system includes steps of pre-filtering contaminated feed liquids blending the filtered liquids in preparation for treating the mixed liquids in parallel or sequential treatment steps utilizing nanofiltration or reverse osmosis, proceeded by or followed by an integrated electrodialysis treatment. A control means selectively directs mixed liquids to each of the treatment units for treatment in parallel or in series depending on the conductivity and residual contaminants in the mixed liquids. In comparison with nanofiltration or reverse osmosis only systems, or electrodialysis only systems, the integrated system provides improved efficiencies for treatment, requires less energy to operate, and reduces maintenance and capital costs.

Method and apparatus for dielectrophoretic separation of particles in a fluid based using array of insulating structures arranged in a fluid flow channel. By utilizing an array of insulating structures, a spatially inhomogeneous electric field is created without the use of the embedded electrodes conventionally employed for dielectrophoretic separations. Moreover, by using these insulating structures a steady applied electric field has been shown to provide for dielectrophoresis in contrast to the conventional use of an alternating electric field. In a uniform array of posts, dielectrophoretic effects have been produced flows having significant pressure-driven and electrokinetic transport. Above a threshold applied electric field, filaments of concentrated and rarefied particles appear in the flow as a result of dielectrophoresis. Above a higher threshold applied voltage, dielectrophoresis produces zones of highly concentrated and immobilized particles. These patterns are strongly influenced by the angle of the array of insulating structures with respect to the mean applied electric field and the shape of the insulating structures.

Systems and methods for delivering bone cement into a bone can include a handle body defining a flow path, a thermal emitter in the handle body to apply energy to bone cement passing through the flow path, a source of bone cement and an injection cannula. The cannula can be in communication with the flow path such that inserting the cannula into a bone can allow a flow of bone cement therethrough to an opening at a distal end of the cannula. Other systems and methods for delivering bone cement into a bone can include an injector body with a handle portion, and a cannula, a bone cement container, a low pressure drive mechanism configured to effect a flow of bone cement from said container to the injector body and a high pressure drive mechanism configured to effect a flow of bone cement through the injector body into the bone.

The present invention is a simulation-based method for rapidly designing, evaluating, and/or optimizing a microfluidic system or biochip. The method provides an environment for schematic generation, system layout, problem setup, simulation, and post-processing. The method comprises a system solver used to simulate microfluidic processes such as pressure driven and electroosmotic flows, analytes dispersion, separation, and mixing, and biochemical reactions. The system solver uses a mixed methodology approach that enables the operation of complete, complex microfluidic systems to be simulated rapidly and iteratively.

The invention provides a digital isothermal nucleic acid detecting device which comprises a micro-fluidic chip, a temperature control system and a pressure driving system. A microfluidic channel for microsphere forming and a reaction section for nucleic acid amplification are formed by the micro-fluidic chip through sequential laminating of a substrate layer, a channel layer arranged on the substrate layer and a cover plate layer arranged on the channel layer. The temperature control system comprises a lower press plate for applying pressure to the substrate from bottom to top and an upper press plate for applying pressure to the cover plate layer from top to bottom, and temperature sensing chips and temperature control heating elements for heating the reaction section are arranged in the upper press plate and the lower press plate. The pressure driving system is connected to the micro-fluidic chip and used for applying pressure to the channel layer in the micro-fluidic chip so that liquid to be detected can flow into the reaction section from the inflow end. According to the scheme, microsphere preparation and nucleic acid amplification and detection are integrated through the digital isothermal nucleic acid detecting device and the detection method, and the advantages of being high in sensitivity and the like are achieved.

Methods of performing separations in microfluidic devices are provided. The methods include the use of pressure to introduce reagents into the device, mix the reagents or react the reagents, and the use of electrokinetic forces to separate the reagents or products. To achieve improved separation efficiency, the depths of the various microfluidic channels are varied. The pressure driven channels provided are deep in comparison to the separation channels in which flow is electrokinetically driven. Also included are microfluidic devices and integrated systems for performing separations in which pressure driven flow and electrokinetic driven flow are integrated.

The invention relates to a differential pad-selection measurement system and method, which are characterized in that: a differential left shell is arranged on a positioning bench, a lower simulation pad is arranged between the differential left shell and a lower semiaxis gear; planetary gears are sleeved on four ends of a cross axle of member to be measured and are arranged in a shaft hole of the differential left shell; a lower puller sleeve arranged in a shaft hole of the lower semiaxis gear is hung on the lower semiaxis gear through an upper edge shoulder of the lower puller sleeve, a measurement tappet is fixedly connected with the lower puller sleeve, a puller spring is arranged between the measurement tappet and the lower puller sleeve, a spring guide sleeve sleeves on the measurement tappet and is supported by the puller spring; an upper top board is arranged on the spring guide sleeve by press mounting manner; and a displacement sensor, a pressure sensor and a proximity switch are respectively arranged in a pressure driving body. The invention can automatically complete accurate measurement of thickness of the differential pad, and can increase product quality and production efficiency.

A mechanical drive system for an accessory gearbox of a gas turbine engine is provided. The engine has a high-pressure drive shaft and a low-pressure drive shaft. The mechanical drive system includes a first tower shaft, a second tower shaft, a first lay shaft, and a second lay shaft. The first tower shaft is driven by the high-pressure drive shaft. The second tower shaft is driven by the low-pressure drive shaft. The first lay shaft is driven by the first tower shaft, and is connected to the accessory gearbox. The second lay shaft is driven by the second tower shaft, and is connected to the accessory gearbox.

Desalination is carried out by a hybrid ion exchange-nanofiltration process in which ion exchange is followed by pressure-driven nanofiltration. Monovalent ions of sodium and chloride of saline water are exchanged for equivalent concentrations of poly-valent ions (for example, sodium ions for magnesium ions or chloride ions for sulfate ions) when passed through ion exchangers in the form of those poly-valent ions. The resultant solution has a lower osmotic pressure than the initial solution containing monovalent sodium and chloride ions, and requires less transmembrane pressure for membrane desalination compared to traditional reverse osmosis. The concentrated reject stream from the membrane process is used as regenerant for the exhausted ion exchanger, which has been converted to monovalent anionic or cationic form.

Liquid flow devices, particularly microfluidic devices, containing solid porous materials. Flow in the devices can be pressure-driven flow and/or electroosmotic flow. The porous materials are preferably pre-shaped, for example divided from a sheet of porous material, so that they can be assembled with liquid-impermeable barrier materials around them. The devices can for example be prepared by lamination. A wide variety of devices, including mixing devices, is disclosed. A mixing device is illustrated in FIG. 23.

The invention belongs to a magnesium alloy wheel multi-directional forming method and a die. The method is characterized by comprising the working procedures of blanking, upsetting, multi-directional extrusion, forward extrusion, flaring, heat treatment, machining and surface treatment, in the working procedures of the multi-directional extrusion, the forward extrusion and the flaring, axial pressure is applied to an axial male die so as to complete the forming of a magnesium alloy wheel, and lateral pressure drives a lateral male die to be connected with a split female die so as to complete the clamping and splitting of the split female die. The method solves the problems of forming and demoulding of a round wheel with small middle part and two large ends, has the advantages of simplifying the technical processes, improving the production efficiency, preventing the generation of burr flash, having high forming precision and the like.

Methods, systems and devices that provide fluid devices with at least one SPE bed adjacent (upstream of) a separation channel which may be in communication with an inlet of a Mass Spectrometer. The fluid device can be configured to operate using independently applied pressures to a BGE reservoir and a sample reservoir for pressure-driven injection that can inject a discrete sample plug into a separation channel that does not require voltage applied to the sample reservoir and can allow for in-channel focusing methods to be used. The methods, systems and devices are particularly suitable for use with a mass spectrometer but optical or other electronic detectors may also be used with the fluidic devices.