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Method for preparing veterinary tilmicosin premix powder medicine

A technology of tilmicosin and premix, which is applied in the direction of drug combination, pharmaceutical formula, powder delivery, etc., can solve the problems of toxic side effects, ineffective treatment of diseases, etc., and achieve strong tissue penetration and stable preparations , enhance the effect of treatment

Inactive Publication Date: 2020-03-27
临沂文一诺知识产权运营有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Because tilmicosin has toxic and side effects on animals, the dosage needs to be cautious, but often a small dosage will not achieve the effect of curing the disease

Method used

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  • Method for preparing veterinary tilmicosin premix powder medicine
  • Method for preparing veterinary tilmicosin premix powder medicine
  • Method for preparing veterinary tilmicosin premix powder medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Prescription: every 100g of medicine contains 18g of tilmicosin, 1.5g of trimethoprim lactate, and the balance is anhydrous glucose.

[0018] Preparation:

[0019] (1) Grind and sieve the tilmicosin, trimethoprim lactate, and anhydrous glucose in the prescription amount, respectively, and set aside;

[0020] (2) Weigh the two raw materials of tilmicosin and trimethoprim lactate, add the same amount of anhydrous glucose as the sum of the two raw materials, and pre-mix for 15 minutes according to the dispersion method;

[0021] (3) Then add the remaining anhydrous glucose and mix thoroughly for 40 minutes, and mix well.

Embodiment 2

[0023] Prescription: every 100g of medicine contains 18g of tilmicosin, 2.5g of trimethoprim lactate, and the balance is anhydrous glucose.

[0024] The preparation method is the same as in Example 1.

Embodiment 3

[0026] Prescription: every 100g of medicine contains 19g of tilmicosin, 1.8g of trimethoprim lactate, and the balance is anhydrous glucose.

[0027] The preparation method is the same as in Example 1.

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Abstract

The invention discloses a method for preparing a veterinary tilmicosin premix powder medicine, and belongs to the technical field of veterinary medicines. The method comprises the following steps: respectively crushing and sieving tilmicosin, trimethoprim lactate and anhydrous glucose; weighing tilmicosin and trimethoprim lactate two raw materials, adding anhydrous glucose, and performing pre-mixing; and then adding anhydrous glucose and performing full mixing to obtain the medicine. The medicine adopts the combined medication of tilmicosin and a synergist, the combination of the two enhancesthe therapeutic effect of the whole powder, and the medicine can be used to treat infectious pleuropneumonia, lung plague, asthma diseases and the like of pigs or cattle. The absorption of the medicine is quick after oral administration, and the medicine has the characteristics of strong tissue penetration, high concentration in lung, and long effective blood concentration maintaining time. Moreover, the preparation is stable, the preparation process is simple, and the use is convenient.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, in particular to a tilmicosin premix powder medicine for veterinary use. Background technique [0002] Tilmicosin is a semi-synthetic macrolide antibacterial drug for animals. Its antibacterial effect is similar to that of tylosin. The sensitive Gram-positive bacteria include Staphylococcus aureus (including penicillin-resistant Staphylococcus aureus), pneumococcus , Streptococcus, Bacillus anthracis, Erysipelas suis, Listeria, Clostridium putrefaction, Clostridium emphysema etc. Sensitive Gram-negative bacteria include Haemophilus, Neisseria meningitidis, Pasteurella, etc., and are also effective against mycoplasma. The activity against Actinobacillus pleuropneumoniae, Pasteurella and Mycoplasma is stronger than Tylosin. It is mainly used for the prevention and treatment of livestock pneumonia, caused by Actinobacillus pleuropneumoniae, Pasteurella, Mycoplasma and other infections,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/706A61K31/505A61P31/04A61P11/00A61P11/06A61K9/14A61K47/26
CPCA61K9/145A61K31/505A61K31/706A61P11/00A61P11/06A61P31/04A61K2300/00
Inventor 不公告发明人
Owner 临沂文一诺知识产权运营有限公司
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