47results about How to "Suitable for commercial mass production" patented technology

The invention discloses a method for preparing protein feed and a protein feed additive by culturing fly maggots with a defined medium. The fly maggot protein feed is prepared through the steps that the defined medium is inoculated with cyclorrhapha flyblows, culturing is performed for 2-6 days, and then drying is performed; the defined medium is prepared from wheat bran, corn flour, soybean meal and plant fiber powder. According to the method, the fly maggots cultured by the defined medium are adopted as raw materials for preparing the protein feed and the protein feed additive, and therefore continuous breeding all year round can be achieved; the raw materials of the medium are all selected from agricultural leftovers and are high in yield and low in cost, and therefore long-term breeding can be achieved; the defined medium used in the formula is comprehensive and balanced in nutrition and meets the all-aspect fly maggot growth requirements that carbohydrate and an appropriate amount of grease are supplied to fly maggot growth, and maggot protein obtained through culture is beneficial for digestion and absorption of livestock and aquatic animals.

The invention relates to the field of medicine, and discloses a refining method of crystal type A azilsartan. The method comprises the following steps: S1, mixing ethyl acetate and absolute ethyl alcohol, heating, and then adding an azilsartan crude product, stirring to be completely dissolved, carrying out filter-pressing; S2, stirring the filtrate in the S1 at 20-25 DEG C to crystallize, filtering, granulating the filter residue through a 24-mesh sieve; drying the raw materials by use of a boiling drying and gradient warming way; drying for 50-70min at an ambient temperature condition, and then drying for 50-70min after warming 40+ / -2 DEG C, wherein the granularity control D (90) is 300-400 microns; drying for 2-3h after warming to 50+ / -2 DEG C, and the granularity control D (90) is 100-200 microns, cooling to obtain an azilsartan finished product. By use of the refining method disclosed by the invention, the dosage of a required organic solvent in refining is greatly reduced; and meanwhile, the stable crystal type A azilsartan is obtained since the raw materials are dried by use of the boiling drying and gradient warming way, the refining yield of 90% or above is acquired, the purity is 99.7% or above, the solvent residue (ethyl alcohol) is less than 0.3%, and the drying time is shortened to 3-6h.

The invention discloses a radio frequency identification (RFID) anti-collision method for an adaptive back-off mechanism. According to the method, different back-off factors are determined and selected according to collision position conditions in the process of identifying a reader, so that all the labels are efficiently and rapidly identified through the adaptive back-off mechanism. According to the method, the adaptive back-off mechanism can be performed, the identification efficiency is greatly improved, and the mechanism is simple and feasible in structure, short in searching time, low in energy consumption and suitable for an RFID application system with lots of strict label and energy consumption requirements.

The invention discloses an abiraterone acetate pharmaceutical composition, a preparation, a preparation method and application thereof. The abiraterone acetate pharmaceutical composition comprises matrix particles and abiraterone acetate, wherein the abiraterone acetate is coated on the surfaces of the matrix particles; and the matrix particles comprise a diluent, a disintegrating agent and an adhesive. The preparation method of the abiraterone acetate pharmaceutical composition comprises the following steps of (1) mixing the diluent, the disintegrating agent, the adhesive and a solvent, and granulating to obtain matrix particles; and (2) dissolving abiraterone acetate in an organic solvent to obtain an abiraterone acetate solution, coating the matrix particles with the abiraterone acetate solution, and drying. According to the abiraterone acetate pharmaceutical composition, the dissolution rate of active ingredients is obviously improved; the medicine absorption is enhanced; the bioavailability is improved; and the taking compliance and safety of a patient are effectively improved.

The invention relates to a preparation method of candesartan cilexetil tablets. The preparation method comprises the steps that candesartan cilexetil, lactose, corn starch, hydroxypropyl cellulose andcarboxymethyl cellulose calcium are weighed, pass through a 50-mesh sieve by using a shaking-type granulator and then are mixed for use, wherein the weight ratio of the candesartan cilexetil to polyethylene glycol 6000 is 4:1-4:2, and the weight ratio of the hydroxypropyl cellulose to the carboxymethyl cellulose calcium is 7:0.4-7:1; the polyethylene glycol 6000 is weighed and added to 95% ethanol, stirring is conducted, water-bath heating and dissolution are conducted by controlling the temperature at 50-60 DEG C, and a wetting agent is prepared for use, wherein the weight ratio of the polyethylene glycol 6000 to the 95% ethanol is 1:6.5-1:13; the sieved and mixed materials are placed in a horizontal wet mixing granulator for dry mixing, the prepared wetting agent is added at the liquidadding speed of 7-8 kg / min, granulation is conducted, discharging is conducted after wet mixing is conducted for 4-6 minutes, and wet granules are finished by a 24-mesh stainless steel sieve on the shaking-type granulator; the working procedures of drying, tabletting and the like are conducted.

The invention discloses a 293T cell culture medium for preparing a retroviral vector. A DMEM culture medium is used as basic liquid, fetal bovine serum, GlutaMax-I, non-essential amino acids, sodium pyruvate, D-(+)-galactose and Hepes are added to prepare the retroviral vector. The invention further discloses a preparation method of the cell culture medium. The preparation method comprises the following steps of (1) adding the D-(+)-galactose to the DMEM culture medium; (2) enabling the D-(+)-galactose to dissolve completely, sequentially adding the fetal bovine serum, the sodium pyruvate, thenon-essential amino acids, the Hepes and the GlutaMax-I, and performing mixing and dissolving; (3) adding the DMEM culture medium to the mixed liquid prepared in the step (2) until the volume is 1L;and (4) performing filtering to obtain a sterile 293T cell culture medium. Compared with a conventional culture medium, the culture medium disclosed by the invention is favorable for realization of stable proliferation of cells, the packing efficiency of viruses is improved, the virus titer is high, the purity is good, and the 293T cell culture medium is suitable for business batch production.

The invention relates to a preparation method of a heat-resistant high-strength Al-Li-Cu-Ce alloy plate. The preparation method improves the heat resistance (heat exposure and high-temperature stretching) of an Al-Li-Cu alloy and realizes the preparation of the heat-resistant high-strength Al-Li-Cu-Ce alloy plate through microalloying of Ce and effective control of the whole process of the preparation process. On the one hand, the precipitation ratio of a T1 (Al2CuLi) phase with heat-resistant potential in the alloy is increased by improving the synergistic effect of Cu / Li in the alloy and pre-deformation before aging, and meanwhile, by adding a trace amount of Ce, coarsening of the T1 (Al2CuLi) phase and refinement of Ce-containing intermetallic compounds can be effectively inhibited by inhibiting diffusion of a main element Cu in the alloy; and the thermal stability and the high-temperature deformation uniformity of the alloy are greatly improved. The method is simple in equipment requirement, high in repeatability and suitable for large-scale commercial production, can be used as a novel aircraft heat-resistant structural part material in the aerospace field, and has a practical application value.

The invention relates to a preparation method of cephalosporin, particularly to a preparation method of cefditoren pivoxil. 7-amino-3-[(Z)-2-(4-methyl-5-thiazolyl) vinyl]-3-cephem-4-carboxylic acid and 2-(2-amino-4-thiazolyl)-2-methoxyiminoacetic are taken as initial raw materials, and the cefditoren pivoxil is obtained through condensation and esterification reactions. The method is simple in process, high in yield, free of highly corrosive solvents and suitable for industrial production.

The invention provides a top-emitting QLED device, comprising a substrate, a patterned pixel electrode, an electron transport layer, a quantum dot light-emitting layer, a hole transport layer, a hole injection layer and an anode arranged in sequence, the electron transport layer and the A transport intermediate layer is stacked between the quantum dot light-emitting layers, an insulating layer with an array structure is provided between the pixel electrodes of the patterned pixel electrodes, and the insulating layer penetrates the electron transport layer and the transport intermediate layer connected, and the transmission intermediate layer and the insulating layer are both made of PMMA material; on the transmission intermediate layer and corresponding to the insulating layer, isolation columns for isolating quantum dot materials of different colors are provided.

The invention discloses a recombinant Lawsonia intracellularis Hsp60 protein monoclonal antibody and its application. The heavy chain variable region of the monoclonal antibody includes HCDR1, HCDR2 and HCDR3, and its amino acid sequences are respectively shown in SEQ ID NO.1 , shown in SEQ ID NO.2 and SEQ ID NO.3; the light chain variable region of the monoclonal antibody includes LCDR1, LCDR2 and LCDR3, and its amino acid sequences are as shown in SEQ ID NO.4, SEQ ID NO.5 and Shown in SEQ ID NO.6. The recombinant Lawsonia intracellularis suis Hsp60 protein monoclonal antibody prepared by the present invention has high purity, good specificity and high sensitivity, and has no cross-reactivity with other intestinal pathogenic bacteria, can be used for ELISA and IFA detection, and is useful for clinical LI diagnosis It is of great significance to research and develop laboratory LI diagnostic technology.

The invention provides a vertical LED structure and a manufacturing method thereof. The manufacturing method comprises the following steps: cutting an epitaxial layer into a plurality of insulated and separated independent light emitting semiconductor layers through the ion implantation technique to replace the traditional complex processes of firstly manufacturing an isolation groove and then filling an insulated material, forming an independent contact layer on each independent light emitting semiconductor layer, then forming a net-shaped-structure DBR reflection layer on each independent contact layer to replace a silver specular reflection layer, and then forming an independent metal function layer on the net-shaped-structure DBR reflection layer. According to the invention, the net-shaped-structure DBR reflection layer is arranged on the independent contact layer to replace the silver specular reflection layer, and the cheap independent metal function layer is arranged on the net-shaped-structure DBR reflection layer, the production cost of an LED is reduced while the problems of brightness improvement and heat dissipation are solved, and the manufacturing method is suitable for large-scale commercialized production.

The invention provides a traditional Chinese medicine for treating infertility caused by impotence. The traditional Chinese medicine is characterized by being prepared mainly from the following components: 30-40g of epimedium, 30-40g of semen cuscutae, 20-30g of cortex phellodendri, 40-45g of polygonum multiflorum, 10-15g of cornu cervi, 10-15g of angelica sinensis and 10-15g of astragalus membranaceus, wherein the concentration of crude drug is 0.1-1.0g / ml. The traditional Chinese medicine has the effects of reinforcing kidneys to replenish essence and promoting fertility, and is mainly used for treating impotence, spermatorrhea and infertility caused by impotence.

A preparation method and application of a hydrogel-modified highly stable carbon-based holographic disc relates to the field of information storage technology, and solves the problem of a preparation method for a storage medium with high information storage stability and high diffraction efficiency, including in Prepare a porous titanium dioxide film on a disc-shaped glass substrate; immerse in a carbon quantum dot solution to load the porous titanium dioxide film with carbon quantum dots to obtain a carbon quantum dot / titanium dioxide composite film; immerse in a silver nitrate solution and prepare by irradiating with an ultraviolet lamp Silver / carbon quantum dots / titanium dioxide composite film; a layer of hydrogel is attached by pulling dipping method. The preparation method of the present invention is convenient and reliable, low in cost, and suitable for commercial mass production, and the prepared optical disk has the performance advantages of high stability, high efficiency and high uniformity of information storage, which makes holographic optical storage stand out in the field of future data storage. Possibly, it can be well applied to the field of holographic data storage.

The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to a sildenafil citrate chewable tablet and a preparation method thereof. The sildenafil citrate chewable tablet comprises sildenafil citrate, filler, excipient, sweetener, lubricant and compound flavoring agent. The present invention hides the taste of sildenafil citrate through repeated dry granulation; it can be taken without water, and the patient compliance is high; at the same time, it can effectively increase the storage stability of sildenafil citrate chewable tablets .

The invention provides a preparation of a digital PCR chip and a modification method thereof. The preparation method comprises the following steps: selecting a silicon material as a chip base layer; polishing a single surface of the chip base layer, embedding a high polymer material into the polished surface of the chip base layer, and removing a protective film on the surface of the high polymermaterial to form a high polymer material panel; baking the high polymer material panel in the above step, and exposing on an exposure machine to form a densely arranged pattern array of reaction micropores on the surface; soaking the densely arranged pattern array obtained in the step 3 in a developing solution, and then drying the densely arranged pattern array; and scribing the high polymer material panel dried in the above step to complete the preparation of the digital PCR chip. The modification method comprises the following steps: carrying out plasma treatment on the digital PCR chip through a plasma machine, and then carrying out digital PCR reaction. The problems that in the prior art, a digital PCR chip is complex in machining process, high in cost, low in chip flux, easy to use and the like are solved.

The invention relates to a method for preparing an upright Au nanocone with high adhesion to the surface of a substrate. A large number of nanoscale corrosion holes are etched on the surface of a silicon wafer; Au is evaporated on the surface of a silicon wafer, and further annealed in the etching process. A large-scale Au-Si binary alloy welding point is formed at the Au-Si interface in the hole as the nano-sized clamping end; Au nanocones are prepared on the Au foil and the Si surface by mechanical separation. This structure significantly improves the binding force between the Au nanocones and the substrate, and provides a new technical means for improving the device stability and service life of SERS detectors and solar cells. The design and preparation process of the invention has no special requirements, easy operation and simple equipment requirements, and is especially suitable for commercial large-scale production.

The invention relates to a wet etching-based preparation method for a light trapping structure with Ag nanowires embedded into a silicon surface. The preparation method comprises the following steps of effectively dispersing the Ag nanowires in an ethanol solution by a low-power ultrasonic dispersion means; uniformly coating the dispersed Ag nanowires on a surface of a silicon wafer by a spin-coating mode; and improving contact between the Ag nanowires and the silicon wafer by an annealing mode. By etching of an etching liquid, the Ag nanowires are embedded into the silicon surface to prepare a novel light trapping, resistance reduction and efficiency improving structure. By the structure, the contact area between the Ag nanowires and the silicon surface is remarkably expanded, and meanwhile, the light trapping capability of the Ag nanowires in silicon is greatly improved within a visible light spectral range. The design and the preparation process provide a novel technical means for improving the efficiency of a device such as a silicon thin film solar cell and an LED.