The invention provides
rivaroxaban tablets and a preparation method for the same, and belongs to the field of
pharmacy. Each
rivaroxaban tablet is prepared from the following components in percentage by
mass: 8.16 to 16.63 percent of
rivaroxaban, 30.00 to 35.00 percent of
lactose monohydrate, 41.56 to 48.94 percent of
microcrystalline cellulose (ph101), 1.63 to 2.49 percent of
sodium dodecyl sulfate, 2.08 to 3.26 percent of hydroxypropyl
methyl cellulose, 3.32 to 4.9 percent of
croscarmellose sodium and 0.49 to 0.67 percent of
magnesium stearate. According to the novel rivaroxaban tablets and the internal and external disintegrant addition mixed-tabletting preparation method,
croscarmellose sodium is internally and externally added, so that the problem of slow disintegration and
dissolution of
azilsartan tablets is solved; with adoption of a
fluidized bed top-spraying
granulation method, three procedures of mixing,
granulation and
drying in a conventional process are implemented by one step, so that production efficiency is improved, prepared granules are uniform in
granularity and high in flowability and compression
formability, and in addition, the problems of sticking, loosening and the like in a tabletting process are also solved.