5884 results about "Chemical agents" patented technology

A tissue welding apparatus is adapted to fuse a first piece of tissue to a second piece of tissue which are disposed in a surface proximate relationship. An elongate shaft carries a first jaw, and a second opposing jaw moveable relative to the first jaw. At least one penetrating member is carried by the first jaw and moveable relative to the second jaw to create a channel through the first piece of material and the second piece of material. A source of heat is coupled to the penetrating member for denaturing the tissue defining the channel. This denatured tissue forms a column binding the first piece of tissue to the second piece of tissue. A chemical agent can be carried to the tissue with the penetrating member.

Chemical agents, such as disulfonamide derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, especially where such agents modulate the activity of the Wnt / β-catenin signaling pathway, and serve to reduce β-catenin levels present in cells, such as cancer cells, or where the agents modulate levels of gene expression in cellular systems, including cancer cells, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents.

A contact lens is provided that is capable of being worn by a user. The lens includes a contact lens body having an eye-engaging surface placeable against a surface of an eye and an outer surface. Microphobic features are provided in the lens for eliminating microbes from the eye-engaging surface. Preferably, these microphobic features are chosen from a group consisting of electrical charge inducing agents, magnetic field inducing agents, chemical agents and textural features. In another embodiment of the present invention, a contact lens is provided that can include a reservoir portion capable of holding a performance enhancement agent for enhancing the performance of the lens. The performance enhancement agent can include such thins as sealant solutions, protective agents, therapeutic agents, anti-microbial agents, medications and reduced size transparent portions. In other embodiments, a wide variety of designs, materials and substances are disclosed for use with contact lenses.

The present invention provides a method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, caused in the biochemical and / or in the functional characteristics of epithelial tissues during the development of tissue atypias, dysplasias, neoplasias and cancers. The method is based, at least in part, on the simultaneous measurement of the spatial, temporal and spectral alterations in the characteristics of the light that is re-emitted from the tissue under examination, as a result of a combined tissue excitation with light and special chemical agents. The topical or systematic administration of these agents result in an evanescent contrast enhancement between normal and abnormal areas of tissue. The apparatus enables the capturing of temporally successive imaging in one or more spectral bands simultaneously. Based on the measured data, the characteristic curves that express the agent-tissue interaction kinetics, as well as numerical parameters derived from these data, are determined in any spatial point of the examined area. Mapping and characterization of the lesion, are based on these parameters.

The invention relates to a desulfurization waste water recycling and zero discharge system and method. The desulfurization waste water recycling and zero discharge system comprises a desulfurization tower, a filter and a nanofiltration device which are sequentially connected, wherein a scale inhibitor dosing device is arranged at the inlet of the nanofiltration device, the concentrated water outlet of the nanofiltration device is connected with the desulfurization tower, the fresh water outlet of the nanofiltration device is connected with a saline water concentrating device, the fresh water outlet of the saline water concentrating device is connected with a fresh water tank, the concentrated water outlet of the salt water concentrating device is connected with a crystallizer, and the condensed water outlet of the crystallizer is connected with the fresh water tank; a drying encapsulating machine is arranged at the solid outlet of the crystallizer. The desulfurization waste water recycling and zero discharge system has the advantages that desulfurization waste water discharged from the desulfurization tower is filtered and then is fed into the nanofiltration device, nanofiltration concentrated water returns to the desulfurization tower, nanofiltration fresh water is treated by virtue of the salt water concentrating device and then is crystallized by virtue of the crystallizer, the obtained fresh water is recycled in the fresh water tank, and salt is separated out, dried into crystallized salt and transported outside after being encapsulated, so that zero discharge of the desulfurization waste water is realized, quality of the recycled fresh water is improved, and a chemical agent and operating cost are saved.

Screening methods and instrumentation for candidate pharmacological agents are applied to discover compounds with muscular and / or neurological activity. The method comprises the use of teleost fish, such as the medaka (Oryzias latipes), which may be stimulated with chemical agents or an electric field to produce, for example, seizure activity and / or convulsive activity. The convulsive behavior may be recorded optically and electrically. Antagonism of the convulsive behavior is produced by application of candidate pharmacological agents to the well containing the fish. The method may include stimulation and antagonism in a plurality of sample wells with a repetitive or simultaneous application of threshold electric fields. The methods and instrumentation can be applied to the study of other serious neurological diseases such as neuropathic pain. In addition the process of assaying the protection of animals to convulsant agents the assay measures pharmacological safety parameters including sedation and cognitive impairment.

A tissue welding apparatus is adapted to fuse a first piece of tissue to a second piece of tissue which are disposed in a surface proximate relationship. An elongate shaft carries a first jaw, and a second opposing jaw moveable relative to the first jaw. At least one penetrating member is carried by the first jaw and moveable relative to the second jaw to create a channel through the first piece of material and the second piece of material. A source of heat is coupled to the penetrating member for denaturing the tissue defining the channel. This denatured tissue forms a column binding the first piece of tissue to the second piece of tissue. A chemical agent can be carried to the tissue with the penetrating member.

The present invention relates to dermal vaccine formulations, designed for targeted delivery of an immunogenic composition to a dermal compartment of skin including the intradermal and epidermal compartments. The dermal vaccine formulations of the invention comprise an antigenic or immunogenic agent, and at least one molecule, e.g., a chemical agent, which enhances the presentation and / or availability of the antigenic or immunogenic agent to the immune cells of the intradermal compartment or epidermal compartment resulting in an enhanced immune response. The dermal vaccine formulations of the invention have enhanced efficacy as the antigenic or immunogenic agent is delivered to the intradermal compartment or epidermal compartment with enhanced presentation and / or availability to the immune cells that reside therein. The enhanced efficacy of the dermal vaccine formulations results in a therapeutically effective immune response after a single intradermal or epidermal dose, with lower doses of antigenic or immunogenic agent than conventionally used, and without the need for booster immunizations.

The invention has supplied biological leaf fertilizer, whose characteristics is that it includes chemical agent, biological organic matter, chelating agent, penetrant and microbe fermentation liquor and the solid raw material and mess ratio are: urea50-55%, potassium dihydrogenphosphate20-25%, potassium chloride 7-8%, boric acid0.3-0.5%, boric acid0.2-0.4%, copper sulfate0.1-0.2%, calcium nitrate0.5-1.5%, magnesium sulfate0.2-0.4%, zinc sulfate0.2-0.4%, manganese sulphate0.2-0.3%, ammonium molybdate0.05-0.1%, fulvic acid14-15%, EDTA chelating agent1-2%, AEO-20 penetrant 0.05-0.1%, mix the raw material of the above mix water 160~70deg.C in the ratio of 2:3, after 24 hours, add microbe fermentation liquor into the liquid filtered by 0.5~1mL / kg, then adjust the PH value to 5.0~6.0, finally, obtain the invention. The leaf fertilizer contains lots of macroelements and all kinds of secondary and microelements, and also contains metabolic product of microbe fermentation, beneficial microbe flora,chelating agent, penetrant and growth regulating agent, without poison, smell and side effect, it is safe and reliable, can increase the quantity and quality of agricultural products.

A unique and novel multi-functional composite fabric and fabrication process for use during chemical, biological, radiological and nuclear countermeasure (CBRNC) events is disclosed. The composite fabric combines the performance characteristics of chemically resistant films and radiation attenuating polymer matrices. The composite fabric offers universal protection against a wide range of military chemical agents, toxic industrial chemicals and materials (TICS and TIMS), biological agents, as well as certain ionizing and non-ionizing forms of radiation. The composite fabric is heat sealable and can be fabricated utilizing hermetically seal seams, and has application in protective clothing and equipment, indoor and outdoor covers, containment systems, bags, drapes, gowns, remains pouches, etc.