44 results about "Tissue fusion" patented technology

A tissue welding apparatus is adapted to fuse a first piece of tissue to a second piece of tissue which are disposed in a surface proximate relationship. An elongate shaft carries a first jaw, and a second opposing jaw moveable relative to the first jaw. At least one penetrating member is carried by the first jaw and moveable relative to the second jaw to create a channel through the first piece of material and the second piece of material. A source of heat is coupled to the penetrating member for denaturing the tissue defining the channel. This denatured tissue forms a column binding the first piece of tissue to the second piece of tissue. A chemical agent can be carried to the tissue with the penetrating member.

An electrosurgical instrument for sealing tissue includes one or more elongated shafts having an end effector assembly attached at a distal end thereof that includes a pair of opposing jaw members movable by an actuator from a first spaced apart position to a second position for grasping tissue. One or both jaw members are adapted to connect to an electrical energy source such that electrosurgical energy can be supplied to tissue disposed therebetween. A controller is coupled to the actuator for regulating a closing pressure between the jaw members and a sensor is configured to provide feedback to the controller regarding a seal pressure of tissue disposed between the jaw members.

A jaw heating element of a handpiece of a thermal tissue operating system is tested on an ongoing basis by supplying a test heater power signal to the jaw heating element between individual thermal tissue operations. Voltage and current through the jaw heating element is sensed and the resistance of the jaw heating element is calculated. If the calculated resistance is outside a range of predetermined acceptable values, an error condition is indicated.

An over shoe for use with electrosurgical instruments having a pair of juxtaposed jaw members pivotably associated with one another, at least one of which includes an electrically conductive surface disposed thereon which is in electrical engagement with an electrosurgical energy source. According to one aspect of the present disclosure, the over shoe includes a tissue contacting wall configured and dimensioned to selectively and substantially overlie the electrically conductive surface of the electrosurgical instrument. The tissue contacting wall is fabricated from a non-conductive material and includes a plurality of apertures formed therethrough. In another embodiment, the tissue contacting wall is electrically conductive and is configured for selective engagement atop on of the jaw members.

An electrode sealing assembly for use with an electrosurgical instrument for sealing tissue includes first and second jaw members which are movable from a first position in spaced relation relative to one another to at least one second position for grasping tissue. The jaw members include electrically conductive sealing plates designed to selectively transmit electrosurgical energy to tissue disposed between the sealing plates. The jaw members also include a thermoelectric cooling plate having a first surface in direct contact with an outer surface of the sealing plate. The thermoelectric cooling plate includes first and second electrical connections on opposite sides of the jaw member. The first connection is configured to selectively transmit a first electrical potential and the second connection is configured to selectively transmit a second electrical potential such that heat generated by the sealing plates is transferred away from the tissue via the thermoelectric cooling plate.

An over shoe for use with electrosurgical instruments having a pair of juxtaposed jaw members pivotably associated with one another, at least one of which includes an electrically conductive surface disposed thereon which is in electrical engagement with an electrosurgical energy source. According to one aspect of the present disclosure, the over shoe includes a tissue contacting wall configured and dimensioned to selectively and substantially overlie the electrically conductive surface of the electrosurgical instrument. The tissue contacting wall is fabricated from a non-conductive material and includes a plurality of apertures formed therethrough. In another embodiment, the tissue contacting wall is electrically conductive and is configured for selective engagement atop on of the jaw members.

A sidewall of biological tissue which surrounds and defines an opening in the tissue is sealed or fused to occlude the opening by compressing apposite sidewall portions and applying sufficient energy to cause the fibers of the compressed apposed sidewall portions to intertwine and fuse with one another to form a permanent seal. The energy application is controlled by detecting a precursor fusion condition while applying the energy and before sufficient energy has been applied to achieve an adequate seal. The application of energy is terminated in a time-delayed relationship to the detection of the precursor fusion condition such that sufficient energy has been applied to achieve an effective seal. The precursor fusion condition is detected upon the peak RF current delivered to the tissue remaining below a threshold value for a threshold time.

An electrosurgical instrument for sealing tissue includes one or more elongated shafts having an end effector assembly attached at a distal end thereof that includes a pair of opposing jaw members movable by an actuator from a first spaced apart position to a second position for grasping tissue. One or both jaw members are adapted to connect to an electrical energy source such that electrosurgical energy can be supplied to tissue disposed therebetween. A controller is coupled to the actuator for regulating a closing pressure between the jaw members and a sensor is configured to provide feedback to the controller regarding a seal pressure of tissue disposed between the jaw members.

A tissue welding apparatus is adapted to fuse a first piece of tissue to a second piece of tissue which are disposed in a surface proximate relationship. An elongate shaft carries a first jaw, and a second opposing jaw moveable relative to the first jaw. At least one penetrating member is carried by the first jaw and moveable relative to the second jaw to create a channel through the first piece of material and the second piece of material. A source of heat is coupled to the penetrating member for denaturing the tissue defining the channel. This denatured tissue forms a column binding the first piece of tissue to the second piece of tissue. A chemical agent can be carried to the tissue with the penetrating member.

Pieces of tissue are fused together by compressing the pieces together at an interface, delivering an impulse of electrical power which is converted into sufficient thermal energy to fuse the pieces together at the interface. The impulse and the fusion occur within a preferable time of 0.5-2.0 seconds but no greater than 4.0 seconds. The temperature of the thermal energy is regulated between 150° C.-200° C. The tissue pieces are compressed to a thickness of 0.05-0.10 mm. Jaws which compress the tissue and transfer the energy have smooth working surfaces with an Ra of 0.15 or less microns to 0.40 microns.

A sidewall of biological tissue which surrounds and defines an opening in the tissue is sealed or fused to occlude the opening by compressing apposite sidewall portions and applying sufficient energy to cause the fibers of the compressed apposed sidewall portions to intertwine and fuse with one another to form a permanent seal. The energy application is controlled by detecting a precursor fusion condition while applying the energy and before sufficient energy has been applied to achieve an adequate seal. The application of energy is terminated in a time-delayed relationship to the detection of the precursor fusion condition such that sufficient energy has been applied to achieve an effective seal. The precursor fusion condition is detected upon the peak RF current delivered to the tissue remaining below a threshold value for a threshold time.

A jaw heating element of a handpiece of a thermal tissue operating system is tested on an ongoing basis by supplying a test heater power signal to the jaw heating element between individual thermal tissue operations. Voltage and current through the jaw heating element is sensed and the resistance of the jaw heating element is calculated. If the calculated resistance is outside a range of predetermined acceptable values, an error condition is indicated.

Biological tissue is sealed or fused to occlude an opening by compressing apposite sidewall portions of the tissue and applying sufficient energy to cause the fibers of the compressed apposed sidewall portions to intertwine and fuse with one another to form a permanent seal. The energy application is controlled by detecting a precursor fusion condition while applying the energy and before sufficient energy has been applied to achieve a permanent seal. The application of energy is terminated in a time-delayed relationship to the detection of the precursor fusion condition. The precursor fusion condition is detected from derivative values of the total accumulated amount of high-frequency energy conducted through the tissue.

RF electrocautery is used to create an anastomosis between vessels or organs, such as the bowel. In an embodiment, tissues are fused together to create a seal between two or more tissue surfaces, for example in a side-to-side bowel anastomosis.

The invention discloses a tissue-engineered cornea and a preparation method thereof. The tissue-engineered cornea comprises three or more layers of laminated structures, each layer of the laminated structure is a composite layer formed in the mode that a fiber scaffold prepared by electrospinning or electrostatic direct writing or light curing 3D printing is cured and composited with one or more of collagen, an acellular matrix and silk fibroin, the space between every two adjacent layers is inoculated with corneal stromal cells and neurons, the corneal stromal cells and the neurons can grow in the direction of fibers of the scaffold, the corneal stromal cells between every two adjacent layers secrete extracellular matrixes to form a tissue structure similar to the human corneal stroma, and the upper surfaces and the lower surface of the laminated structures are inoculated with corneal epithelial cells and corneal endothelial cells. The tissue-engineered cornea can simulate the corneastructure well, is easy to prepare and good in biocompatibility and is easily fused with tissue.

The present invention provides a method of using locally administered collagenase as a non-invasive means of enhancing cell release from the cartilage or fibrocartilage tissues adjacent to a disease or injury site. The subsequent migration of cells from these tissues into the lesion or wound, followed by deposition of the appropriate extracellular matrix, results in closure of the lesion or fusion of a tissue gap.

Biological tissue is sealed or fused to occlude an opening by compressing apposite sidewall portions of the tissue and applying sufficient energy to cause the fibers of the compressed apposed sidewall portions to intertwine and fuse with one another to form a permanent seal. The energy application is controlled by detecting a precursor fusion condition while applying the energy and before sufficient energy has been applied to achieve a permanent seal. The application of energy is terminated in a time-delayed relationship to the detection of the precursor fusion condition. The precursor fusion condition is detected from derivative values of the total accumulated amount of high-frequency energy conducted through the tissue.

The present invention relates to medical article, and is especially one kind of orthopaedic internal fixer and its making process. The orthopaedic internal fixer is one threaded cylinder with conic front end, two radial slots in the edge of its back end, central axial through hole and inner thread in the back end of the through hole. It may be installed and detached with a special tool easily, and its screw may be machined according to the method of patent No. 200510031414.1. It is made with the bone of ox, horse, sheep, pig or other animal as material and through the steps of taking bone, machining, defatting, cleaning, packing and sterilizing. It can fuse with human body's bone skeleton and may be degraded slowly.

The invention provides a gel-biological ceramic cartilage implant for cartilage replacement repair. The cartilage implant comprises a calcium and phosphorus contained biological ceramic support and hydrogel. One face of the hydrogel and the calcium and phosphorus contained biological ceramic support are bonded together through biological glue, wherein the Young modulus of the hydrogel is 0.2-3 MPa, and the water content is 60-80%; the Young modulus of the calcium and phosphorus contained biological ceramic support is 1-20 GPa, a plurality of holes are formed in the support and the diameter of the holes is 200-600 micrometers. The upper gel of the implant has the mechanical property similar to cartilage, the lower support is matched with the mechanical property of a load bearing component, the function of alternate cartilage replacement repair can be achieved, the tissue fusion can be gradually formed by cartilage and subchondral bones in the bone reconstruction process, and the implant is used for cartilage replacement repair of cartilage defects of the load-bearing component. The invention further provides a preparation method and application of the cartilage implant.

An energy source of a thermal tissue operating system performs self-tests using simulation heating elements and jaw heating elements in tissue-grasping jaws of a handpiece. Power is supplied to the simulation heating elements and verified, without necessitating connection of a handpiece. Power is also delivered and verified to each of the two jaw heating elements when the handpiece is connected. Voltage and current are measured by peak hold detectors, and the peak hold detectors are tested to verify correct operation. All tests may be combined in a power on self-test (POST).

The present invention provides a method of using locally administered collagenase as a non-invasive means of enhancing cell release from the cartilage or fibrocartilage tissues adjacent to a disease or injury site. The subsequent migration of cells from these tissues into the lesion or wound, followed by deposition of the appropriate extracellular matrix, results in closure of the lesion or fusion of a tissue gap.

The invention discloses a textile fabric with folds. The textile fabric is woven by using warps and wefts in a plain circulation and variable circulation tissue fusion mode, wherein the warps and the wefts in the plain circulation tissue form a top-down tissue structure, the first wefts in the variable circulation tissue float on the warps and do not form interweaving points, and the second wefts and the warps form a top-down tissue structure. The warps are 20D single-pore polyamide yarns, and the wefts are 20D single-pore polyamide yarns and 60S Tencel. The textile fabric with folds is light, thin and flowing, the vertical folds are natural, and the colored transverse stripes are obvious. At the variable tissue, the single-pore polyamide yarns floating on the upper layer have strong decoration. The weaving process is simple, the effect is obvious, the Tencel content is high, and the manufactured clothes worn close to the body is comfortable and environmentally-friendly.

A novel A1-B-A2 polymer having a number average molecular weight of 10000 to 100000 is provided that has excellent bioabsorbability so as to disappear in a predetermined period of time even when embedded in a large amount in the body, has good kinetic properties, and is useful for preparing tissue anti-adhesion films. This polymer is composed of segments A1 and A2 each having at least either of modified and unmodified amino acid groups, and segment B composed of PEG having a number average molecular weight of 8000 to 50000. The polymer contains both the modified and unmodified amino acid groups, the content of the modified amino acids is 20 to 85 mol % of all the amino acids in the polymer, and segment A1 is bonded to one end of segment B and segment A2 is bonded to the other end of segment B.

The present invention provides a method of using locally administered collagenase as a non-invasive means of enhancing cell release from the cartilage or fibrocartilage tissues adjacent to a disease or injury site. The subsequent migration of cells from these tissues into the lesion or wound, followed by deposition of the appropriate extracellular matrix, results in closure of the lesion or fusion of a tissue gap.

A tissue fusing clamp comprises a pair of components pivotably attached, having a component end with a finger loop for manipulation of the components, and each component having a fusing end comprising fusing jaws that are able to be motivated towards one another into a closed position. A depressor depresses tissue between the tissue areas to be fused, resulting in a tightening of the tissue after fusing. The fusing jaws may each comprise a fusing element, such as an ultrasonic transducer or laser, that is in electrical communication with a fusing circuit for providing electrical power to the fusing element as desired by a user. The fusing circuit may be controlled by use of a foot switch or other controller that may be manipulated by the user when it is desired to activate the fusing elements.

A novel A1-B-A2 polymer having a number average molecular weight of 10000 to 100000 is provided that has excellent bioabsorbability so as to disappear in a predetermined period of time even when embedded in a large amount in the body, has good kinetic properties, and is useful for preparing tissue anti-adhesion films. This polymer is composed of segments A1 and A2 each having at least either of modified and unmodified amino acid groups, and segment B composed of PEG having a number average molecular weight of 8000 to 50000. The polymer contains both the modified and unmodified amino acid groups, the content of the modified amino acids is 20 to 85 mol % of all the amino acids in the polymer, and segment A1 is bonded to one end of segment B and segment A2 is bonded to the other end of segment B.

The invention relates to a tissue ablation, cutting and merging system. The tissue ablation, cutting and merging system comprises a handle assembly, a shaft assembly, a working part, a circuit systemand a power source, wherein a trigger switch is arranged on a controller of the circuit system; a trigger part is arranged on a trigger; when the trigger moves in the direction facing a gripping handle of a housing until a force limiting mechanism works, the trigger part touches the trigger switch to switch on the trigger switch; and when the trigger moves in the direction away from the gripping handle of the housing, the trigger part is separated from the trigger switch to switch down the trigger switch. According to the tissue ablation, cutting and merging system disclosed by the invention,the trigger switch can only be switched on when the force limiting mechanism works, so that the tissue ablation, cutting and merging system disclosed by the invention can perform tissue ablation, cutting and merging under a set working pressure, the operation effect is more stable, accidental injury which is possibly caused by misoperation and clinical effect differences of vascular occlusion, tissue ablation, tissue cutting and the like caused by different clamping force used by different surgeons are effectively avoided, and the tissue ablation, cutting and merging system is safer and more effective.