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2540 results about "Organ of Corti" patented technology
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The organ of Corti, or spiral organ, is the receptor organ for hearing and is located in the mammalian cochlea. This highly varied strip of epithelial cells allows for transduction of auditory signals into nerve impulses' action potential. Transduction occurs through vibrations of structures in the inner ear causing displacement of cochlear fluid and movement of hair cells at the organ of Corti to produce electrochemical signals.
Single fold device for tissue fixation
ActiveUS7914543B2Convenient guidancePrevent kinking and pinchingSuture equipmentsStapling toolsBody organsStoma
A system for tissue approximation and fixation is described herein. A device is advanced in a minimally invasive manner within a patient's body to create one or several divisions or plications within a hollow body organ. The system comprises a stapler assembly having a tissue acquisition member and a tissue fixation member. The stapler assembly approximates tissue from within the hollow body organ with the acquisition member and then affixes the approximated tissue with the fixation member. In one method, the system can be used as a secondary procedure to reduce the size of a stoma within the hollow body organ.
Owner:ETHICON ENDO SURGERY INC
System for tissue approximation and fixation
ActiveUS7097650B2Convenient guidancePrevent kinking and pinchingSuture equipmentsStapling toolsBody organsBiomedical engineering
A system for tissue approximation and fixation is described herein. The devices are advanced in a minimally invasive manner within a patient's body to create one or several divisions or plications within a hollow body organ. The system comprises a tissue acquisition and folding device and a tissue stapling or fixation device, each of which is used together as a system. The acquisition device is used to approximate tissue regions from within the hollow body organ and the stapling device is advanced through a main lumen defined through the acquisition device and is used to affix the approximated tissue. The stapling device is keyed to maintain its rotational orientation relative to the acquisition device as well as to provide the user positional information of the stapling device. The acquisition device is also configured to provide lateral stability to the stapling device prior to the stapling device being clamped onto tissue.
Owner:ETHICON ENDO SURGERY INC
Apparatus and methods for protecting adjacent structures during the insertion of a surgical instrument into a tubular organ
A device for protecting tissues and structures adjacent to a tubular organ during performance of a surgical procedure on a portion of the tubular organ. Various embodiments may comprise a member that may be deployed through a surgical instrument in a first configuration and expanded to a second configuration such that when in the second configuration, the protective member may extend substantially around an outer circumference of the portion of the tubular organ.
Owner:ETHICON ENDO SURGERY INC
Devices and methods for stomach partitioning
A device and method for remodeling or partitioning a body cavity, hollow organ or tissue tract includes graspers operable to engage two or more sections of tissue within a body cavity and to draw the engaged tissue between a first and second members of a tissue remodeling tool. The two or more pinches of tissue are held in complete or partial alignment with one another as staples or other fasteners are driven through the pinches, thus forming a four-layer tissue plication. Over time, adhesions formed between the opposed serosal layers create strong bonds that can facilitate retention of the plication over extended durations, despite the forces imparted on them by stomach movement. A cut or cut-out may be formed in the plication during or separate from the stapling step to promote edge-to-edge healing effects that will enhance tissue knitting / adhesion.
Owner:BAROSENSE
Intussusception and anastomosis apparatus
Apparatus for intratubular intussusception and anastomosis of a hollow organ portion including a cylindrical enclosure, coaxial intratubular intussusception device, for intussusception and clamping means. The apparatus also includes an intratubular anastomosis apparatus for joining organ portions after intussusception thereof with an anastomosis ring and crimping support element. The ring is formed of a shape memory alloy wire, for crimping adjacent organ portions against the crimping support element so as to cause anastomosis therebetween. The ring assumes a plastic or malleable state, at a lower temperature and an elastic state at a higher temperature. The apparatus further includes the crimping support element for intratubular insertion so as to provide a support for crimping the organ portions against the support element. The apparatus additionally includes a surgical excising means, for excising an intussuscepted organ portion, after crimping adjacent intussuscepted organ walls against the crimping support element with the anastomosis ring.
Owner:NITI SURGICAL SOLUTIONS
Adhesive Mechanical Fastener for Lumen Creation Utilizing Tissue Necrosing Means
A two piece anastomosis device for attaching two organs together and creating a passage between the organs is disclosed. The anastomosis device has a first tissue clamping ring and a second tissue clamping ring that are brought together to clamp tissue therebetween and cut off the flow of blood to the tissue. The tissue clamping rings are locked together with an adhesive, and over time, causes the clamped tissue to necrose and slough off. The sloughed tissue creates a passageway through the anastomosis device. A method of using the fastener to create a bypass passageway between the stomach and small intestine is disclosed.
Owner:ETHICON ENDO SURGERY INC
Catheter for conducting a procedure within a lumen, duct or organ of a living being
In an embodiment, the invention provides a catheter suitable for use in performing a procedure within a vessel, lumen or organ of a living having a distal end which is steerable, such as upon the application of compression. The catheter may be of the over the wire type, or alternatively may be a rapid exchange catheter. The catheter may provide for a rotating element which may be used to open a clogged vessel, or alternatively to provide information about adjacent tissues, such as may be generated by imaging or guiding arrangements using tissue detection systems known in the art, e.g., ultrasound, optical coherence reflectometry, etc. For rapid exchange catheters having a rotating element, there is provided an offset drive assembly to allow the rotary force to be directed from alongside the guidewire to a location coaxial to and over the guidewire.
Owner:KENSEY NASH CORP
System and method for advancing, orienting, and immobilizing on internal body tissue a catheter or other therapeutic device
This invention provides a system and method that allows a therapeutic device, such as an atrial fibrillation microwave ablation catheter or ablation tip to be guided to a remote location within a body cavity and then accurately immobilized on the tissue, including that of a moving organ, such as the heart. In various embodiments, the system and method also enables accurate movement and steering along the tissue, while in engagement therewith. Such movement and engagement entails the use of vacuum or microneedle structures on at least two interconnected and articulated immobilizers that selectively engage to and release from the tissue to allow a crawling or traversing walking across the organ as the therapeutic catheter / tool tip applies treatment (AGE devices). In further embodiments that lack a movement capability (AID devices), the immobilizers allow a predetermined position for the introduced device to be maintained against the tissue while a treatment is applied to the location adjacent thereto. In the exemplary AID devices, variety of steering mechanisms and mechanisms for exposing and anchoring a catheter against the underlying tissue can be employed. In the exemplary AGE devices, a variety of articulation and steering mechanisms, including those based upon pneumatic / hydraulic bellows, lead screws and electromagnetic actuators can be employed.
Owner:ELECTROPHYSIOLOGY FRONTIERS SPA
Shape lockable apparatus and method for advancing an instrument through unsupported anatomy
Apparatus and methods are provided for placing and advancing a diagnostic of therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube, a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The overtube may be selectively stiffened to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.
Owner:USGI MEDICAL CORP
Endoscopic stapler having camera
Owner:MEDIGUS LTD
Circumferential full thickness resectioning device
An apparatus for performing endoluminal anastomosis of an organ comprises an operative head including an endoscope receiving lumen for slidably receiving a flexible endoscope therein, the operative head including an annular tissue receiving space extending around a circumference of a distal end thereof and a stapling mechanism for firing staples around an entire circumference of the tissue receiving space and a tissue gripping mechanism for drawing into the tissue receiving space a portion of tissue extending around an entire circumference of the organ.
Owner:BOSTON SCI SCIMED INC
Retractor system for internal in-situ assembly during laparoscopic surgery
A method of laparoscopic (or robotic) surgery, using a hand-port, comprising providing a trocar port operably disposed within a first abdominal incision opening of a patient, providing a hand-port operably disposed within a second abdominal incision opening, introducing an elongate positioner dimensioned to extend through the trocar, introducing a spatulate element through the hand port and joining the spatulate element to the positioner. The procedure further comprises removing an internal organ or other tissue from the operating area in order to make room and add visibility for the laparoscopic intervention, detaching the spatulate element from the positioner, and withdrawing the positioner through the trocar port and the spatulate through the hand port.
Owner:JOHNSTON WILLIAM
Surgical devices and methods using magnetic force to form an anastomosis
InactiveUS20080200934A1Maintain alignmentExcision instrumentsWound clampsMagnetic tension forceNatural orifice
A method for forming an anastomosis between first and second organs in a patient using a hollow receptacle that is inflatable with magnetic material. The method may include forming openings through the first and second organs utilizing a hole-forming instrument inserted into the organs through a natural orifice in the patient. The hollow receptacle may be supported on a catheter assembly that is also inserted through the patient's natural orifice and through the openings in the first and second organs and is positioned within the second organ. The hollow receptacle is then inflated with magnetic material and magnetic force is applied within the force organ to draw the inflated receptacle toward the first organ such that the inflated receptacle retains the second organ in sealing contact with the first organ while maintaining the alignment between the first and second openings to create an anastomosis between the first and second organs.
Owner:ETHICON ENDO SURGERY INC
Intravascular delivery system for therapeutic agents
Described herein is a system for intravascular drug delivery system, which includes a reservoir implantable a blood vessel, an intravascular pump fluidly coupled to the reservoir and an anchor expandable into contact with a wall of the blood vessel to retain the system within the vasculature. Delivery conduits may be extend from the reservoir and are positionable at select locations within the vasculature for target drug delivery to select organs or tissues.
Owner:WILLIAMS MICHAEL S +2
Surgical retractor
A biocompatible deformable retractor provides desired advanced organ retaining during surgical procedures. The retractor is generally self-retaining once deployed and provides surgical field without the interference from the retained organs. The deployed retractor may adopt convex, planar, or concave configurations inside a body cavity. The retractor comprises a deformable resilient frame and a deformable membrane, is approximately planar or a non-planar convex shape in its natural un-deformed configuration. The membrane can be transparent to provide additional viewing capability of the retained organs.
Owner:COOK MEDICAL TECH LLC
Devices and methods for placement of partitions within a hollow body organ
InactiveUS8449560B2Minimize and eliminate cross acquisitionFacilitate acquisitionSuture equipmentsStapling toolsBody organsBiomedical engineering
Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body to create one or more plications within the hollow body organ. A tissue treatment device attached to a distal end of a flexible elongated member and has a cartridge member opposite an anvil member. The cartridge member and the anvil member are movable between a closed position and an open position, and a moveable barrier is disposed between the cartridge and anvil members to help acquire a dual fold of tissue. The tissue treatment device can be repositioned to form multiple plications within the organ.
Owner:ETHICON ENDO SURGERY INC
Device and method for endoluminal therapy
InactiveUS7666195B2Minimizing dilationMinimize timeSuture equipmentsSurgical needlesOrgan wallOrgan of Corti
Owner:KELLEHER BRIAN +1
High intensity ablation device
ActiveUS7179254B2Improve performanceOvercome limitationsUltrasound therapySurgical instruments for heatingMicrowaveHigh intensity
An apparatus for ablating tissue, the apparatus having first and second opposing jaws operative to compress tissue to be allayed therebetween, the first jaw having a first ablation surface directing ablative energy into the tissue and the second jaw having a second ablation surface reflecting incident ablative energy into the tissue. The ablative energy may be ultrasonic, microwave, cryoablation, radio-frequency, photodynamic, laser, and cautery energy. The instrument may also have a pointed tip for piercing tissue, allowing the instrument to clamp the tissue wall of a hollow organ before ablation. Alternately, the instrument may clamp two or more tissue layers of a hollow organ without piercing prior to clamping an ablation.
Owner:ETHICON INC
Obesity treatment with electrically induced vagal down regulation
At least one of a plurality of disorders of a patient characterized at least in part by vagal activity innervating at least one of a plurality of organs of the patient is treated by a method that includes positioning a neurostimulator carrier around a body organ of the patient where the organ is innervated by at least a vagal trunk. An electrode is disposed on the carrier and positioned at the vagal trunk. An electrical signal is applied to the electrode to modulate vagal activity by an amount selected to treat the disorder. The signal may be a blocking or a stimulation signal.
Owner:RESHAPE LIFESCIENCES INC
Devices and methods for placement of partitions within a hollow body organ
ActiveUS9028511B2Minimize and eliminate cross acquisitionFacilitate acquisitionNon-surgical orthopedic devicesObesity treatmentBody organsGastric bypass
Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body, e.g., transorally, endoscopically, percutaneously, etc., to create one or several divisions or plications within the hollow body organ. Such divisions or plications can form restrictive barriers within a organ, or can be placed to form a pouch, or gastric lumen, smaller than the remaining stomach volume to essentially act as the active stomach such as the pouch resulting from a surgical Roux-En-Y gastric bypass procedure. Moreover, the system is configured such that once acquisition of the tissue by the gastroplasty device is accomplished, any manipulation of the acquired tissue is unnecessary as the device is able to automatically configure the acquired tissue into a desired configuration.
Owner:ETHICON ENDO SURGERY INC
Method and device for use in endoscopic organ procedures
InactiveUS7220237B2Maintain alimentary flowImprove adhesionDiagnosticsSurgical instrument detailsStomaBody organs
Methods and devices for use in tissue approximation and fixation are described herein. The present invention provides, in part, methods and devices for acquiring tissue folds in a circumferential configuration within a hollow body organ, e.g., a stomach, positioning the tissue folds for affixing within a fixation zone of the stomach, preferably to create a pouch or partition below the esophagus, and fastening the tissue folds such that a tissue ring, or stomas, forms excluding the pouch from the greater stomach cavity. The present invention further provides for a liner or bypass conduit which is affixed at a proximal end either to the tissue ring or through some other fastening mechanism. The distal end of the conduit is left either unanchored or anchored within the intestinal tract. This bypass conduit also includes a fluid bypass conduit which allows the stomach and a portion of the intestinal tract to communicate.
Owner:ETHICON ENDO SURGERY INC
Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA
In a first aspect, the present invention features methods for differentiating DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA of an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in DNA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from a mother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient. In a fourth aspect, the present invention features kits for differentiating DNA species originating from different individuals in a biological sample.
Owner:THE CHINESE UNIVERSITY OF HONG KONG
Methods and apparatus for perfusion of isolated tissue structure
Organs and other tissue structures are isolated and perfused with a therapeutic agent. Isolation is effected by endovascularly positioning catheters having occlusion balloons within the arteries or other blood vessels which supply blood to the organ. Similarly, blood flow from the organ back to the patient's circulatory system is blocked by endovascularly positioning one or more catheters carrying occlusion members within the veins or other blood vessels leading from the organ. The therapeutic agent may then be perfused through the organ in either an antegrade or retrograde fashion using the endovascularly positioned catheters while maintaining isolation.
Owner:PINPOINT THERAPEUTICS
Prosthetic repair fabric
InactiveUS6258124B1Promoting enhanced tissue ingrowthControl incidenceDiagnosticsLigamentsProsthesisSpermatic cord
A prosthetic repair fabric and method for repairing an inguinal hernia in the inguinal canal. The prosthesis including a layer of mesh fabric that is susceptible to the formations of adhesions with sensitive tissue and organs, and a barrier layer that inhibits the formation of adhesions with sensitive tissue and organs. The mesh fabric including a medial section and a lateral section that are configured to be positioned adjacent the medial corner and the lateral end of the inguinal canal, respectively, when the prosthesis is placed in the inguinal canal to repair the defect. The barrier layer is positioned on the mesh fabric to inhibit the formation of adhesions between the spermatic cord and the mesh fabric. At least a portion of the lateral section of the mesh fabric is free of the barrier layer on both of its sides to promote enhanced tissue ingrowth therein. The barrier layer may include at least one flap that is to be folded through the mesh fabric to isolate the spermatic cord from internal edges of the fabric when the spermatic cord is routed through the prothesis.
Owner:CR BARD INC
Locking mechanisms for fixation devices and methods of engaging tissue
InactiveUS7604646B2Prevent movementReduce frictional contactSuture equipmentsAnnuloplasty ringsEngineeringSurgical department
Owner:EVALVE
System and method for three-dimensional reconstruction of a tubular organ
InactiveUS7742629B2Easy to useEliminate potential incorrect distortionImage analysisOptical rangefindersOptical densityDensitometry
Embodiments of the present invention include methods and systems for three-dimensional reconstruction of a tubular organ (for example, coronary artery) using a plurality of two-dimensional images. Some of the embodiments may include displaying a first image of a vascular network, receiving input for identifying on the first image a vessel of interest, tracing the edges of the vessel of interest including eliminating false edges of objects visually adjacent to the vessel of interest, determining substantially precise radius and densitometry values along the vessel, displaying at least a second image of the vascular network, receiving input for identifying on the second image the vessel of interest, tracing the edges of the vessel of interest in the second image, including eliminating false edges of objects visually adjacent to the vessel of interest, determining substantially precise radius and densitometry values along the vessel in the second image, determining a three dimensional reconstruction of the vessel of interest and determining fused area (cross-section) measurements along the vessel and computing and presenting quantitative measurements, including, but not limited to, true length, percent narrowing (diameter and area), and the like.
Owner:PAIEON INC
Elevated coupling liquid temperature during HIFU treatment method and hardware
InactiveUS20080281200A1Avoid necrosisEnhanced couplingUltrasonic/sonic/infrasonic diagnosticsUltrasound therapyLiquid temperatureUltrasonic vibration
A medical procedure utilizes a high-intensity focused ultrasound instrument having an applicator surface, a liquid-containing bolus or expandable chamber acting as a heat sink, and a source of ultrasonic vibrations, the applicator surface being a surface of a flexible wall of the bolus, the source of ultrasonic vibrations being in operative contact with the bolus. The applicator surface is placed in contact with an organ surface of a patient, the source is energized to produce ultrasonic vibrations focused at a predetermined focal region inside the organ, and a temperature of liquid in the bolus is controlled while the applicator surface is in contact with the organ surface to control temperature elevation in tissues of the organ between the focal region and the organ surface to necrose the tissues to within a desired distance from the organ surface.
Owner:US HIFU
Intra-gastric fastening devices
InactiveUS6994715B2Easy accessReduce riskSuture equipmentsSurgical needlesStomach wallsTethered Cord
Intra-gastric fastening devices are disclosed herein. Expandable devices that are inserted into the stomach of the patient are maintained within by anchoring or otherwise fixing the expandable devices to the stomach walls. Such expandable devices, like inflatable balloons, have tethering regions for attachment to the one or more fasteners which can be configured to extend at least partially through one or several folds of the patient's stomach wall. The fasteners are thus affixed to the stomach walls by deploying the fasteners and manipulating the tissue walls entirely from the inside of the organ. Such fasteners can be formed in a variety of configurations, e.g., helical, elongate, ring, clamp, and they can be configured to be non-piercing. Alternatively, sutures can be used to wrap around or through a tissue fold for tethering the expandable devices. Non-piercing biased clamps can also be used to tether the device within the stomach.
Owner:ETHICON ENDO SURGERY INC
Intraluminal electrode apparatus and method
At least one of a plurality of disorders of a patient associated with vagal activity innervating at least one of a plurality of organs of the patient at an innervation site are treated by positioning a neurostimulator carrier within a body lumen of the patient. An electrode disposed on the carrier is positioned at a mucosal layer of the lumen. An electrical signal is applied to the electrode to modulate vagal activity by an amount selected to treat the disorder. The signal may be a blocking or a stimulation signal.
Owner:RESHAPE LIFESCIENCES INC
Mesh for pelvic floor repair
InactiveUS7087065B2Reduce vaginal prolapseIncrease heightSuture equipmentsAnti-incontinence devicesPelvisPelvic floor repair
A woven mesh is provided for supporting tissue or an organ within a female patient's pelvis, and a method for using the same. The mesh includes a central portion having a width, a length, first and second ends, and first and second side edges, and first and second wing portions extending from the first and second ends of the central portion respectively. The first and second wing portions each have a width, a length, and first and second peripheral edges. The width of the wing portions are each greater than the width of the central portion, and when positioned within the female patient, the central portion is positioned below and supports the tissue or organ. A mesh is also provided having woven fibers with voids therebetween, and having a central portion and first and second ends. The average size of the voids at least in the central portion is at least 25–50 mm2, and when positioned within the patient, the central portion is positioned below and supports the tissue or organ.
Owner:ETHICON INC
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