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55 results about "Tissue acquisition" patented technology
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Tissue Acquisition. In 1999, TRIO became one of the first groups to successfully establish a pre-randomization tumour tissue acquisition and central laboratory process whereby patients’ tumour tissues are collected and evaluated centrally for a specific biomarker prior to entry into a clinical trial.
Single fold device for tissue fixation
ActiveUS7914543B2Convenient guidancePrevent kinking and pinchingSuture equipmentsStapling toolsBody organsStoma
A system for tissue approximation and fixation is described herein. A device is advanced in a minimally invasive manner within a patient's body to create one or several divisions or plications within a hollow body organ. The system comprises a stapler assembly having a tissue acquisition member and a tissue fixation member. The stapler assembly approximates tissue from within the hollow body organ with the acquisition member and then affixes the approximated tissue with the fixation member. In one method, the system can be used as a secondary procedure to reduce the size of a stoma within the hollow body organ.
Owner:ETHICON ENDO SURGERY INC
System for tissue approximation and fixation
ActiveUS7097650B2Convenient guidancePrevent kinking and pinchingSuture equipmentsStapling toolsBody organsBiomedical engineering
Owner:ETHICON ENDO SURGERY INC
Single-fold system for tissue approximation and fixation
InactiveUS20050177176A1Prevent kinkingAvoid pinchingSurgical pincettesSurgical staplesBody organsSingle fold
A single fold system for tissue approximation and fixation is described herein. The devices are advanced in a minimally invasive manner within a patient's body to create at least one fold within a hollow body organ. The system comprises a tissue acquisition and folding device and a tissue stapling or fixation device, each of which is used together as a system. The acquisition device is used to approximate a single fold of tissue from within the hollow body organ and the stapling device is advanced through a main lumen defined through the acquisition device and is used to affix the tissue. The stapling device is keyed to maintain its rotational orientation relative to the acquisition device and to provide the user positional information of the stapling device. The acquisition device is also configured to provide lateral stability to the stapling device prior to the stapling device being clamped onto tissue.
Owner:ETHICON ENDO SURGERY INC
Devices and methods for placement of partitions within a hollow body organ
InactiveUS8449560B2Minimize and eliminate cross acquisitionFacilitate acquisitionSuture equipmentsStapling toolsBody organsBiomedical engineering
Owner:ETHICON ENDO SURGERY INC
Devices and methods for placement of partitions within a hollow body organ
ActiveUS9028511B2Minimize and eliminate cross acquisitionFacilitate acquisitionNon-surgical orthopedic devicesObesity treatmentBody organsGastric bypass
Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body, e.g., transorally, endoscopically, percutaneously, etc., to create one or several divisions or plications within the hollow body organ. Such divisions or plications can form restrictive barriers within a organ, or can be placed to form a pouch, or gastric lumen, smaller than the remaining stomach volume to essentially act as the active stomach such as the pouch resulting from a surgical Roux-En-Y gastric bypass procedure. Moreover, the system is configured such that once acquisition of the tissue by the gastroplasty device is accomplished, any manipulation of the acquired tissue is unnecessary as the device is able to automatically configure the acquired tissue into a desired configuration.
Owner:ETHICON ENDO SURGERY INC
Devices and methods for placement of partitions within a hollow body organ
ActiveUS20060151568A1Limit acquisitionFacilitate acquisitionSuture equipmentsStapling toolsBody organsBiomedical engineering
Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body to create one or more plications within the hollow body organ. A tissue treatment device attached to a distal end of a flexible elongated member and has a cartridge member opposite an anvil member. The cartridge member and the anvil member are movable between a closed position and an open position relative to one another, and the cartridge member is re-loadable with a removable staple cartridge to form multiple plications within the organ with the same tissue treatment device.
Owner:ETHICON ENDO SURGERY INC
Devices and methods for placement of partitions within a hollow body organ
ActiveUS20050203547A1Limit acquisitionFacilitate acquisitionSuture equipmentsDiagnosticsBody organsGastric bypass
Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body, e.g., transorally, endoscopically, percutaneously, etc., to create one or several divisions or plications within the hollow body organ. Such divisions or plications can form restrictive barriers within a organ, or can be placed to form a pouch, or gastric lumen, smaller than the remaining stomach volume to essentially act as the active stomach such as the pouch resulting from a surgical Roux-En-Y gastric bypass procedure. Moreover, the system is configured such that once acquisition of the tissue by the gastroplasty device is accomplished, any manipulation of the acquired tissue is unnecessary as the device is able to automatically configure the acquired tissue into a desired configuration.
Owner:ETHICON ENDO SURGERY INC
Single fold device for tissue fixation
ActiveUS20050256533A1Convenient guidancePrevent kinking and pinchingSuture equipmentsStapling toolsBody organsStoma
A system for tissue approximation and fixation is described herein. A device is advanced in a minimally invasive manner within a patient's body to create one or several divisions or plications within a hollow body organ. The system comprises a stapler assembly having a tissue acquisition member and a tissue fixation member. The stapler assembly approximates tissue from within the hollow body organ with the acquisition member and then affixes the approximated tissue with the fixation member. In one method, the system can be used as a secondary procedure to reduce the size of a stoma within the hollow body organ.
Owner:ETHICON ENDO SURGERY INC
Devices and methods for placement of partitions within a hollow body organ
ActiveUS20050203548A1Limit acquisitionFacilitate acquisitionNon-surgical orthopedic devicesObesity treatmentBody organsGastric bypass
Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body, e.g., transorally, endoscopically, percutaneously, etc., to create one or several divisions or plications within the hollow body organ. Such divisions or plications can form restrictive barriers within a organ, or can be placed to form a pouch, or gastric lumen, smaller than the remaining stomach volume to essentially act as the active stomach such as the pouch resulting from a surgical Roux-En-Y gastric bypass procedure. Moreover, the system is configured such that once acquisition of the tissue by the gastroplasty device is accomplished, any manipulation of the acquired tissue is unnecessary as the device is able to automatically configure the acquired tissue into a desired configuration.
Owner:ETHICON ENDO SURGERY INC
Surgical circular stapler with tissue retention arrangements
Surgical instruments and procedures for performing a circular anastomosis of a tubular organ. The surgical instruments may include selectively deployable tissue acquisition members configured to puncture through a portion of the tubular organ and position the portion of the organ adjacent to a fastener face of a staple cartridge supported in the instrument. At least one cutting member may be radially deployed and rotated to sever the positioned portion of organ from a distal portion of the organ. An anvil may be employed to draw another portion of the organ adjacent to the portion of organ positioned adjacent to the fastener face of the staple cartridge. The staples may then be deployed through the adjacent portions of organ and an annular knife may be advanced through the adjacent organ portions to complete the anastomosis.
Owner:ETHICON ENDO SURGERY INC
Circular stapling instruments with secondary cutting arrangements and methods of using same
Surgical instruments are disclosed. Various non-limiting embodiments may include an elongated shaft that has a distal end portion that is configured to operably support a circular staple cartridge therein. A tissue acquisition shaft may be rotatably supported within said elongated shaft and have a distal portion that protrudes distally beyond the distal end portion of the elongated shaft. At least one tissue acquisition member may be pivotally attached to the distal end portion of the tissue acquisition shaft such that the tissue acquisition members are selectively pivotable from a retracted position to deployed positions upon application of a deployment motion thereto. A rotatable cutting member may be operably supported adjacent to the tissue acquisition member and being selectively rotatable about the central axis upon application of a cutting actuation motion thereto.
Owner:ETHICON ENDO SURGERY INC
Tissue acquisition system and method of use
A tissue acquisition system includes radio frequency (RF) cutter loops which are extendable out a cannula to cut cylindrical tissue samples from a tissue of interest in a patient. The cannula includes inner and outer cannulae which are mutually rotatable and include cutouts through which the cutting loop can be rotated and longitudinally extended to perform the cuts. The tissue samples are then aspirated proximally through the cannula for collection.
Owner:SENORX
Methods and apparatus for securing medical instruments to desired locations in a patient's body
Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
Owner:SENORX
Devices and methods for placement of partitions within a hollow body organ
InactiveUS20070233161A1Minimize and eliminate cross acquisitionFacilitate acquisitionSuture equipmentsDiagnosticsBody organsBiomedical engineering
Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body to create one or more plications within the hollow body organ. A tissue treatment device attached to a distal end of a flexible elongated member and has a cartridge member opposite an anvil member. The cartridge member and the anvil member are movable between a closed position and an open position relative to one another, and the cartridge member is re-loadable with a removable staple cartridge to form multiple plications within the organ with the same tissue treatment device.
Owner:ETHICON ENDO SURGERY INC
System for tissue approximation and fixation
ActiveUS20050080438A1Prevent kinkingAvoid pinchingSuture equipmentsStapling toolsBody organsBiomedical engineering
A system for tissue approximation and fixation is described herein. The devices are advanced in a minimally invasive manner within a patient's body to create one or several divisions or plications within a hollow body organ. The system comprises a tissue acquisition and folding device and a tissue stapling or fixation device, each of which is used together as a system. The acquisition device is used to approximate tissue regions from within the hollow body organ and the stapling device is advanced through a main lumen defined through the acquisition device and is used to affix the approximated tissue. The stapling device is keyed to maintain its rotational orientation relative to the acquisition device as well as to provide the user positional information of the stapling device. The acquisition device is also configured to provide lateral stability to the stapling device prior to the stapling device being clamped onto tissue.
Owner:ETHICON ENDO SURGERY INC
Devices and methods for placement of partitions within a hollow body organ
ActiveUS8628547B2Minimize and eliminate cross acquisitionFacilitate acquisitionSuture equipmentsStapling toolsBody organsGastric bypass
Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body, e.g., transorally, endoscopically, percutaneously, etc., to create one or several divisions or plications within the hollow body organ. Such divisions or plications can form restrictive barriers within a organ, or can be placed to form a pouch, or gastric lumen, smaller than the remaining stomach volume to essentially act as the active stomach such as the pouch resulting from a surgical Roux-En-Y gastric bypass procedure. Moreover, the system is configured such that once acquisition of the tissue by the gastroplasty device is accomplished, any manipulation of the acquired tissue is unnecessary as the device is able to automatically configure the acquired tissue into a desired configuration.
Owner:ETHICON ENDO SURGERY INC
System for tissue approximation and fixation
InactiveUS20060271076A1Convenient guidancePrevent kinking and pinchingSuture equipmentsStapling toolsBody organsBiomedical engineering
Owner:ETHICON ENDO SURGERY INC
Method and device for use in endoscopic organ procedures
InactiveUS20050101977A1Minimize infection riskLower the volumeNon-surgical orthopedic devicesObesity treatmentBody organsBiomedical engineering
Methods and devices for use in tissue approximation and fixation are described herein. The present invention provides, in part, methods and devices for acquiring tissue folds in a circumferential configuration within a hollow body organ, e.g., a stomach, positioning the tissue folds for affixing within a fixation zone of the stomach, preferably to create a pouch or partition below the esophagus, and fastening the tissue folds such that a tissue ring, or stomas, forms excluding the pouch from the greater stomach cavity. The present invention further provides devices for performing a transoral, endoscopic hollow organ division, including a tissue acquisition device capable of acquiring the desired tissue circumferentially, and a fixation mechanism to secure the muscular layers of the acquired tissue such that the desired healing response is achieved.
Owner:ETHICON ENDO SURGERY INC
Single fold system for tissue approximation and fixation
ActiveUS20070112364A1Prevent kinking and pinchingPrecise positioningSuture equipmentsStapling toolsBody organsSingle fold
A single fold system for tissue approximation and fixation is described herein. The devices are advanced in a minimally invasive manner within a patient's body to create at least one fold within a hollow body organ. The system comprises a tissue acquisition and folding device and a tissue stapling or fixation device, each of which is used together as a system. The acquisition device is used to approximate a single fold of tissue from within the hollow body organ and the stapling device is advanced through a main lumen defined through the acquisition device and is used to affix the tissue. The stapling device is keyed to maintain its rotational orientation relative to the acquisition device and to provide the user positional information of the stapling device. The acquisition device is also configured to provide lateral stability to the stapling device prior to the stapling device being clamped onto tissue.
Owner:ETHICON ENDO SURGERY INC
Isolated culture method of human amnia mesenchymal stem cells
InactiveCN105062959AGood repeatabilityShort training periodSkeletal/connective tissue cellsEmbryonic cellsDigestionCancer research
The invention discloses an isolated culture method of human amnia mesenchymal stem cells, which comprises the following steps: carrying out human placenta amnia tissue acquisition, amnia tissue disinfection, washing, shredding and mixed collagenase digestion to obtain mesenchymal stem cells, and carrying out mesenchymal stem cell in-vitro culture. The method can obtain abundant mesenchymal stem cells, which have the advantages of uniform and stable phenotype and high multiplication capacity and have the multidirectional differentiation potential, from the human amnia tissues; and the culture medium in-vitro amplification is performed to purify the cells, thereby satisfying the quantity for cryopreservation or clinical use. The method has the advantages of short cell culture period and high repetitiveness. The stem cells obtained by the method have the phenotypes of CD105<+>, CD90<+> and CD73<+>.
Owner:GENESIS STEMCELL REGENERATIVE MEDICINE ENG CO LTD
Needle biopsy systems and methods
InactiveUS20150141868A1Increase volumeEasy diagnosisSurgical needlesVaccination/ovulation diagnosticsTissue sampleActuator
This document provides medical device systems and methods for obtaining tissue samples. For example, this document provides medical device systems and methods for transbronchial needle biopsy tissue acquisition. In some cases, a needle biopsy system includes an actuator device, an outer needle with a lumen therethrough, and an inner needle at least partially disposed within the lumen. The outer needle can extend distally from the actuator device. A distal tip of the inner needle can be capable of being fully disposed within the lumen. The inner needle can extend distally from the actuator device. The actuator device can be configured to translate the outer needle proximally and distally. The actuator device can be configured to translate the inner needle proximally and distally independently of the outer needle.
Owner:MAYO FOUND FOR MEDICAL EDUCATION & RES +1
Methods and apparatus for securing medical instruments to desired locations in a patient's body
Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
Owner:SENORX
Devices and methods for endoluminal plication
InactiveUS20130153624A1Lower the volumeEffective positioningSuture equipmentsStapling toolsBiomedical engineeringPosterior wall
Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create multiple tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a tissue acquisition and fixation system is disclosed including a stapling member having first and second jaws that are effective to apply at least one staple to tissue engaged between the jaws, a tissue acquisition member coupled to at least one of the first and second jaws, and a secondary tissue acquirer coupled to the tissue acquisition member. The secondary tissue acquirer is configured to engage tissue and maintain the tissue in position relative to the tissue acquisition member.
Owner:ETHICON ENDO SURGERY INC
Tissue cutting devices having hemostasis capability and related methods
InactiveUS20070066985A1Effectively stopSurgical needlesVaccination/ovulation diagnosticsMedical deviceBiomedical engineering
Various embodiments of a medical device (e.g., tissue acquisition device) having a separate hemostasis capability and related methods of use are disclosed. The device may include an elongated tubular member having a proximal end and a distal end, a tissue cutting member proximate the distal end of the tubular member, and a hemostatic member proximate the distal end of the tubular member and adjacent the tissue cutting member. At least one of the tissue cutting member and the hemostatic member may be fixedly connected to the tubular member.
Owner:BOSTON SCI SCIMED INC
Endoscopic therapeutic device, living body tissue analyzing and processing system, and sample-taking method for tissue analysis process
The endoscope treatment tool (1) of the present invention is provided with: an elongated insertion part (15) inserted into the living body after passing through the treatment tool channel (10) of the endoscope (2); A tubular puncture needle (16) that penetrates the front end of the biological tissue; a tissue collection means (18) that collects the biological tissue while the puncture needle (16) is pierced into the biological tissue; and Collection means (18) Tissue processing means (22) for processing the collected biological tissue for analysis.
Owner:OLYMPUS CORP
Single fold device for tissue fixation
InactiveUS20110166585A1Convenient guidancePrevent kinking and pinchingLaproscopesObesity treatmentStomaBody organs
A system for tissue approximation and fixation is described herein. A device is advanced in a minimally invasive manner within a patient's body to create one or several divisions or plications within a hollow body organ. The system comprises a stapler assembly having a tissue acquisition member and a tissue fixation member. The stapler assembly approximates tissue from within the hollow body organ with the acquisition member and then affixes the approximated tissue with the fixation member. In one method, the system can be used as a secondary procedure to reduce the size of a stoma within the hollow body organ.
Owner:ROTH ALEX T +6
Systems and methods for calibrating functional magnetic resonance imaging of living tissue
Embodiments of the present invention relate to systems and methods for calibrating functional magnetic resonance imaging of living tissue. For example, a calibration method includes providing a contrast signal simulation device configured for generating one or more pre-determined contrast simulation signals selected from a group consisting of BOLD and BOSS contrast simulation signals that simulate at least one contrast signal generated by living tissue of a subject and positioning the contrast signal simulation device adjacent to the subject. The method includes using an imaging instrument to take first and second data sets from the subject's tissue while the contrast signal simulation device is disposed adjacent to the subject and while generating and not generating the one or more pre-determined contrast simulation signals, respectively. The method also includes using the first and second data sets to determine at least one figure of merit of the imaging instrument, the contrast simulation device, and / or the living tissue.
Owner:UNIV OF FLORIDA RES FOUNDATION INC
Methods and apparatus for securing medical instruments to desired locations in a patient's body
Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
Owner:SENORX
Biopsy device with automatic aspiration
ActiveUS20140114210A1Avoid aspirationSurgical needlesVaccination/ovulation diagnosticsBiopsy deviceBiomedical engineering
The invention provides a disposable endometrial biopsy device comprising an elongated blunt-end catheter with distally placed tissue acquisition side-hole and proximally attached aspiration syringe with spring-loaded plunger having latching mechanism to release plunger for induction of aspiration. The device has a pin-hole channel or filter acting as a tissue trap between the catheter channel and the syringe in order to prevent aspiration of tissue into the body of the syringe.
Owner:ZINNANTI WILLIAM
Method and device for tissue acquisition or closure
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
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