1955 results about "Early detection" patented technology

The present invention provides a hyperspectral imaging system which demonstrates changes in tissue oxygen delivery, extraction and saturation during shock and resuscitation including an imaging apparatus for performing real-time or near real-time assessment and monitoring of shock, including hemorrhagic, hypovolemic, cardiogenic, neurogenic, septic or burn shock. The information provided by the hyperspectral measurement can deliver physiologic measurements that support early detection of shock and also provide information about likely outcomes.

Various embodiments of the invention provide solutions (including inter alia, systems, methods and software) for dealing with online fraud. In particular, various embodiments of the invention can provide early warning of an online fraud, for instance by finding suspicious domains and / or monitoring those domains for activity. If a suspicious domain shows activity (for example, if a web site associated with the domain becomes active), one or more actions may be taken with respect to the domain.

A system and method for communicating data and signals through the Medical Implant Communication Service Band using a repeater or base station in the proximity to an implantable device within a patient is disclosed. In a preferred embodiment, the device is capable for early detection and monitoring of congestive heart failure in a patient. Impedance measurements, or other health parameters depending on the type of implantable device or sensor used, are sent using a bi-directional low-power radio operating in the MICS band to a nearby base station which may provide signal processing and analysis. The base station may have an interface to one or more communications networks to connect to a remote location. The system and method of the present invention permits a healthcare professional to monitor an ambulatory patient's condition at a remote location and to program the implanted device.

A system and method for early detection of identity theft are provided. An authorized user establishes an identity with an organization's computing system and registers a mobile device and a notification device with the organization's computing system. When a use of the identity is attempted, a record associated with the identity is retrieved and a request is sent to the registered mobile device for location information. The current location of the mobile device is compared to the location of the source of the request for authorization. If the current location of the mobile device is not within an area of the source of the authentication request, information about the attempted use is compared with the registered notification criteria. If the conditions of the attempted use fall within the notification criteria, a notification message is sent to the notification device.

The systems described herein include tools for computer-assisted evaluation of objective characteristics of pathologies. A diagnostic system arranged according to the teachings herein provides computer support for those tasks well suited to objective analysis, along with human decision making where substantial discretion is involved. Collaborative diagnosis may be provided through shared access to data and shared control over a diagnostic tool, such as a telemicroscope, and messaging service for clinicians who may be at remote locations. These aspects of the system, when working in cooperation with one another, may achieve improved diagnostic accuracy or early detection for pathologies such as lymphoma.

Systems, methods, and computer-readable media are disclosed for improved early detection and alerts related to fraudulent transactions. Certain embodiments involve sending an alert message to a mobile device associated with a portable consumer device. The alert includes notification of a recent transaction related to an account that is associated with the portable consumer device. A reply message is then received in response to the alert message. The response may indicate that the recent transaction is fraudulent. A risk engine is then updated with data associated with the reply message. In one potential additional embodiments, analysis and projections of potential future fraud are created or updated based on the reply message.

Disclosed is a system for detecting an acute myocardial infarction (i.e., a heart attack) at the earliest possible time and promptly warning the patient that he should immediately seek medical care. The present invention includes an implantable electronic system that can sense a change in the patient's electrogram that is indicative of a heart attack. If a heart attack is sensed, the device would then cause an implantable and / or externally located alarm to be actuated to warn the patient of his condition and a medical practitioner at a remote diagnostic center would receive the patient's electrogram for analysis. The patient or a caretaker would then be informed to self-inject medication through a subcutaneous, pass-through drug port that can be a separate device or integrated into the implanted device that is designed for the early detection of a heart attack. Since an implantable heart pacemaker or defibrillator already has within its structure many of the elements required for the device to recognize a heart attack, it would be expeditious to add a capability to these existing devices to detect a heart attack, have a pass-through drug port and provide an implantable and / or external alarm means to inform the patient to take appropriate action.

Apparatus and method for the early detection of increased performance impairment, incapacitation or drowsiness of a person, particularly of a person gripping an object such as a steering wheel. A wrist band is worn by the person and an electrical sensor is pressed against the person's skin by the band to sense physiological conditions by detecting various parameters at the wrist and analyzing them to provide an indication of the onset of drowsiness in the person. Some of the parameters analyzed include EMG, temperature, response to stimulation and muscular activity at the wrist. A description of a shock-absorbing wrist monitor is disclosed.

Vehicles operation is often regulated by vehicle operation policies, such as operator and vehicle licensing, safe operation rules, and emissions testing, as well as advisory policies (e.g., safety tips) and infrastructure policies (e.g., traffic congestion reduction). However, enforcement of vehicle operation policies may be infrequent, costly, inaccurate, and / or ineffective for particular types of problems. Presented herein are techniques for enforcing vehicle operation policies using vehicle telemetrics detected by a vehicle telemetry sensor and reported to telemetric monitoring components during operation of the vehicles. For example, in-car emissions sensors may regularly report emissions data to roadside monitors, enabling continuous monitoring, early detection of emissions problems, and accurate measurements during road travel. Additional telemetric exchange may promote the persuasion of advisory vehicle operation policies, such as safety tips, and the transmission of travel information of interest to other vehicles and individuals, such as road hazards, traffic congestion, and available parking spots.

The present invention relates to methods for the diagnosis, evaluation, and treatment of mood disorders, particularly bipolar disorder. In particular, patient test samples are analyzed for the presence and amount of members of a panel of biallelic markers comprising one or more specific markers for bipolar treatment and one or more non-specific markers for bipolar treatment. A variety of markers are disclosed for assembling a panel of markers for such diagnosis and evaluation. Algorithms for determining proper treatment are disclosed. A diagnostic kit for a panel of said markers is disclosed. In various aspects, the invention provides methods for the early detection and differentiation of mood disorders or bipolar treatment. Methods for screening therapeutic compounds for mood disorders are disclosed. The invention (1) gives methods providing rapid, sensitive and specific assays that can greatly increase the number of patients that can receive beneficial treatment and therapy, thereby reducing the costs associated with incorrect diagnosis, and (2) provides methods for improved therapies.

The present invention relates to methods for the diagnosis and evaluation of stroke and stroke sub-type. A variety of bio-markers are disclosed for assembling a panel for such diagnosis and evaluation. Methods are disclosed for selecting markers and correlating their combined levels with a clinical outcome of interest. In various aspects: the invention provides methods for early detection and differentiation of stroke subtypes, for determining the prognosis of a patient presenting with stroke symptoms, and identifying a patient at risk for hemorrhagic transformation after thrombolyic therapy. Methods are disclosed that provide rapid, sensitive and specific assays to greatly increase the number of patients that can receive beneficial stroke treatment and therapy, and reduce the costs associated with incorrect stroke diagnosis.

The present invention relates to methods for the diagnosis and evaluation of cardiovascular illness, particularly stroke, myocardial and other cardiovascular damage damage, hypertension treatment. In particular, patient test samples are analyzed for the presence and amount of members of a panel of markers comprising one or more specific markers for cardiovascular illness or hypertension treatment and one or more non-specific markers for cardiovascular illness or hypertension treatment. A variety of markers are disclosed for assembling a panel of markers for such diagnosis and evaluation. Algorithms for determining proper treatment are disclosed. A diagnostic kit for a panel of said markers is disclosed. In various aspects, the invention provides methods for the early detection and differentiation of cardiovascular illness or hypertension treatment. Invention methods provide rapid, sensitive and specific assays that can greatly increase the number of patients that can receive beneficial treatment and therapy, reduce the costs associated with incorrect diagnosis, and provide important information about the prognosis of the patient.

Methods and apparatus for early detection and identification of a threat such as individuals carrying hidden explosive materials, land mines on roads, etc. are disclosed. One method comprises illuminating a target with radiation at a first polarization, collecting first radiation reflected from the target which has the same polarization as the first polarization, illuminating a target with radiation at a second polarization, and collecting second radiation reflected from the target which has the same polarization as the second polarization. A threat determination is then made based on the difference between the energy values of the first and second collected radiations. In other embodiments, the difference between energy values is used in conjunction with an evaluation of the returned energy in comparison with returned energy from other targets in order to additionally assess whether the primary target is a threat.

The present invention provides a power regulation system and method with high speed signal settling capabilities for providing rapid active transient response to a microelectronic device. An active transient response system includes a power supply configured to receive external and / or internal signals indicating the occurrence of transient load conditions and to respond to the transient load conditions based on one or more of these signals. The system may further include a transient suppressor configured for early detection of transients, assisting in transient suppression, and early signaling of transient activity to the power supply.The system provides rapid recovery to steady state operation from the active transient response mode by using a digital compensator to quickly modifying the duty cycle and provide a voltage offset proportional to the transient microprocessor load step. Recovery is further improved by current rephasing techniques.

A method is disclosed for providing early detection, classification, and reporting of health-related events in a population. The method includes capturing sets of specific emergency room patient information from a subset of the population as the patient information is first electronically entered into, for example, an electronic medical record (EMR). The patient information is pre-processed, transmitted to and stored in a central database in a central computer facility. The patient information is sorted and analyzed by the central computer facility to detect any health-related events in the population and to generate corresponding alerts. The alerts are electronically reported to designated authorities such as health officials and other government authorities such as the CDC.

An endoscopic system for in-vivo tissue characterization, using a nonirradiative electromagnetic sensor, is described. The endoscopic system is further configured to employ several follow-up procedures, for example, biopsy sampling, localized surgery, dispensing a medicament, and the like, so that on the whole, the endoscopic system provides for the early detection of cancerous and pre-cancerous tissue, in vivo, and for the application of immediate follow-up procedures to any such tissue.

A highly sensitive assay is disclosed which utilizes a method for gene specific primed amplification of mRNA libraries from rare cells and rare transcripts found in blood. The assay allows detection of rare mRNA (10 copies / cell) found in 1 to 10 cells isolated through immunomagnetic enrichment. The assay is an improvement over multiplex PCR and allows efficient detection of rare coding sequences for circulating carcinoma cells in the blood. The methods are useful in profiling of cells isolated from tissues or body fluids and serves as an adjunct to clinical diagnosis of diverse carcinomas including early stage detection and classification of circulating tumor cells. Monitoring of nucleic acid and protein profiles of cells either in conventional or microarray formats, facilitates management of therapeutic intervention including staging, monitoring response to therapy, confirmation of remission and detection of regression.

Embodiments of the invention provide for improved early detection of fraud through user-defined monitoring of financial account information and communication of alerts and notifications of user-defined individualized potentially-fraudulent account activity to users. Embodiments of the invention permit an account fraud detection service provider to provide account monitoring services. The user may use the fraud detection service provider to monitor any number and type of financial accounts, and the user may define account notification rules or filters under which the user may choose to be notified of certain potentially-fraudulent account activities. The user may receive alerts and / or notifications of the user-selected account activities using a method selected by the user, and may therefore maintain awareness of account activities and be alerted of any troubling activity in a manner most convenient and effective for the user's needs.

An intrusion detection system (IDS) is enhanced to operate in a cluster of such systems, and IDSs organized into a cluster cooperate to exchange IP reputation influencing events information between or among the cooperating systems in real-time to enhance overall system response time and to prevent otherwise hidden attacks from damaging network resources. An IDS includes an IP reputation analytics engine to analyze new and existing events, correlate information, and to raise potential alerts. The IP reputation analytics engines may implement an algorithm, such as a pattern matching algorithm, a continuous data mining algorithm, or the like, to facilitate this operation. Clustering IDS endpoints to share IP reputation influencing events, using the cluster-wide view to determine IP reputation, and feeding the cluster-wide view back to the IDS endpoints, provides for enhanced and early detection of threats that is much more reliable and scalable as compared to prior art techniques.

The invention discloses a bearing fault detection method based on a manner of controlling stochastic resonance by an external periodic signal. According to the method provided in the invention, after a bearing fault signal is converted by a variable metric method, the converted signal is input in a bistable system; meanwhile, an external single frequency periodic signal is taken as a control signal to act directly on the system; contact barrier height of the bistable system and an escape rate of Kramers are changed by continuously adjusting an amplitude of the control signal. Therefore, stochastic resonance can be generated or increased artificially; a spectral value of an output power spectrum at the position of an input signal frequency can be effectively improved; and thus a characteristic signal of a bearing fault can be detected accurately at last. The detection method provided in the invention enables the effective control of the stochastic resonance to be realized, thereby providing a novel method for early detection of equipment faults.

The invention relates to the field of elevators. In order to early discover and diagnose A elevator fault, the invention adopts the technical scheme that an elevator fault diagnosis and early-warning method based on data drive is achieved by means of a remote service center, a fault diagnosis and prediction terminal and an elevator controller, and the method comprises the steps as follows: firstly, elevator fault data are mined to obtain characteristic information in an elevator fault data stream, and the mined result is stored in an elevator fault case base of the fault diagnosis and prediction terminal; secondly, an elevator fault knowledge base on the fault diagnosis and prediction terminal is updated by the elevator fault case base; thirdly, the case retrieval is carried out on the characteristic of a new elevator fault problem, and the fault diagnosis is carried out on the elevator system by adopting the fault diagnosis method based on the case-base reasoning; and finally information with the characteristic that is most similar with that of the new elevator fault problem is acquired through retrieval of the knowledge or the case in the elevator fault knowledge base to solve the diagnosis problem. The method is mainly suitable for manufacturing and designing image sensors.

The invention is a computer system that provides early detection alert and response to electronic threats (eThreats) in large wide area networks, e.g. the network of an Internet Services Provider or a Network Services Provider. The system of the invention accomplishes this by harnessing the processing power of dedicated hardware, software residing in specialized servers, distributed personal computers connected to the network, and the human brain to provide multi-layered early detection, alarm and response. The layers comprise: a Protection Layer, which detects and eliminates from the network data stream eThreats known to the system; a Detection Layer, which detects and creates signatures for new eThreats that are unknown to the system; an Expert Analysis Layer, which comprises a group of human experts who receive information from various components of the system and analyze the information to confirm the identity of new eThreats; and a Collaborative Detection & Protection Layer, which detects potential new eThreats by processing information received from various system agents and users. A Dynamic Sandbox Protection Layer associated with the distributed personal computers connected to the network. can optionally be part of the system of the invention.

A tire monitoring system providing tire status and notifying or warning the vehicle operator of early detection of imminent tire failure and performance degradation; thus improving safety by preventing blowouts from occurring, lengthening tire life by encouraging preventive maintenance, and improving fuel mileage by encouraging the operator to fill the tire to its proper pressure or repair it. The system monitors temperature of the rim of the wheel to which the tire is attached, such temperature being transmitted to the vehicle operator or other interested parties via means such as radio frequency.

The present invention relates to medical devices and methods for early detection of acute myocardial infarction in a patient. In particular, the invention relates to a device and method for detecting the presence of biomarker analytes in a specimen which are indicative of a potential acute myocardial infarction in the patient.

An apparatus for electrocardiogram measurement including a first non-conductive pad. A first and second electrode are disposed on the first non-conductive pad. The first electrode represents any one of V4, V5, or V6 and the second electrode is either (i) positioned on the subject below the first electrode in order to represent left leg (LL) or (ii) is placed on a line on the subject defined by the V4, V5, and V6 precordial positions in order to represent any one of V4, V5, or V6 not represented by the first electrode. The apparatus includes a second non-conductive pad. A third electrode is disposed on the second non-conductive pad. The third electrode is a right arm (RA) electrode that is for positioning at a position that is on or close to the right arm of the subject. Each electrode is adapted for electrical connection with the skin in order to receive and transmit electrical impulses. The apparatus further includes an electrical connection that connects each electrode disposed on the first and second non-conductive pads to an electrocardiological measuring apparatus. The electrocardiological measuring apparatus is capable of measuring a first lead and a different second lead without user intervention.

Threat risks to an enterprise are detected and assessed by assembling singular threats identified using both direct and behavioral threat indicators into composite threats to create complex use cases across multiple domains, and to amplify risks along kill chains of known attacks for early detection. Composite threat risk scores are computed from risk scores of singular threats to exponentially increase with the number of events observed along the kill chain. Composite threats are combined with normalized values of static risk and inherent risk for an entity of the enterprise to produce an entity risk score representative of the overall risk to the entity.

A method and kit for detecting the immediate or early onset of renal disease and injury, including renal tubular cell injury, utilizing NGAL as an immediate or early on-set biomarker in a sample of blood serum. NGAL is a small secreted polypeptide that is protease resistant and consequently readily detected in the blood serum following renal tubule cell injury. NGAL protein expression is detected predominantly in proximal tubule cells, in a punctuate cytoplasmic distribution reminiscent of a secreted protein. The appearance NGAL in the serum is related to the dose and duration of renal ischemia and nephrotoxemia, and is diagnostic of renal tubule cell injury and renal failure. NGAL detection is also a useful marker for monitoring the nephrotoxic side effects of drugs or other therapeutic agents.

The present invention relates to systems and methods for early detection, assessment, monitoring and prevention of pathophysiological conditions originating and / or emanating from skin or localized tissues, including but not limited to acute or chronic episodes of soft tissue pathology, wound, injury, dermatological or rheumatoid condition where bio-signal patterns, biomarkers or other identifiable elements or references would deviate from baseline. Specifically, the present invention relates to methods and systems specially designed and adapted for early detection of a latent pathogenic bio-signal anomaly using multiple aggregated sensors before the anomaly would otherwise be detectable.