80 results about "Tubular cell" patented technology

A method and kit for detecting the immediate or early onset of renal disease and injury, including renal tubular cell injury, utilizing NGAL as an immediate or early on-set biomarker in a sample of blood serum. NGAL is a small secreted polypeptide that is protease resistant and consequently readily detected in the blood serum following renal tubule cell injury. NGAL protein expression is detected predominantly in proximal tubule cells, in a punctuate cytoplasmic distribution reminiscent of a secreted protein. The appearance NGAL in the serum is related to the dose and duration of renal ischemia and nephrotoxemia, and is diagnostic of renal tubule cell injury and renal failure. NGAL detection is also a useful marker for monitoring the nephrotoxic side effects of drugs or other therapeutic agents.

A rig mat is formed by rectangular panels fastened end to end by cooperating connectors. In one arrangement the first connector is C-shaped shaped to form a slot and the second T-shaped shaped with a flange of the T wider than the mouth inserted through the mouth. In a second arrangement two L shaped connectors are interengaged with an additional flat plate which defines a slot with an end of one of the L-shaped connectors. The panels are composite and formed from a honeycomb core panel with a foam material filling the tubular cells and a fibrous reinforcing cover sheets extending over the top and bottom of the panel. The cover sheets are filled with a set resin material which extends into the porous fibrous material of the walls of the core panel so as to form an integral structure of the resin extending between the walls and the sheets.

A method and kit for detecting the early onset of renal tubular cell injury, utilizing NGAL as an early urinary biomarker. NGAL is a small secreted polypeptide that is protease resistant and consequently readily detected in the urine following renal tubule cell injury. NGAL protein expression is detected predominantly in proximal tubule cells, in a punctate cytoplasmic distribution reminiscent of a secreted protein. The appearance NGAL in the urine is related to the dose and duration of renal ischemia and nephrotoxemia, and is diagnostic of renal tubule cell injury and renal failure. NGAL detection is also a useful marker for monitoring the nephrotoxic side effects of drugs or other therapeutic agents.

A front door 20 includes a first door component 22 and a second door component 34. The first door component 22 forms an inner side portion of a door main body 21, and the second door component forms an inner side portion of the door main body 21 and has functional parts located inside the vehicle. The first and second door components 22, 34 have honeycomb structural bodies 23, 41, respectively. The honeycomb structural bodies 23, 41 are entirely formed of synthetic resin. The honeycomb structural bodies 23, 41 include honeycomb portions 24, 42, which are composed of numerous tubular cells 26, 44, 45 separated by partition walls 25, 43, and sealing plate portions 27, 28, 46, 47 that are located on the outer side and the inner side of the honeycomb portions 24, 42 and seal the cells 26, 44. The door components 22, 34 are joined to each other at least at a part of the adjacent sealing plate portions 28, 46 of the honeycomb structural bodies 23, 41.

A method and kit for detecting the early onset of renal tubular cell injury, utilizing NGAL as an early urinary biomarker. NGAL is a small secreted polypeptide that is protease resistant and consequently readily detected in the urine following renal tubule cell injury. NGAL protein expression is detected predominantly in proximal tubule cells, in a punctate cytoplasmic distribution reminiscent of a secreted protein. The appearance NGAL in the urine is related to the dose and duration of renal ischemia and nephrotoxemia, and is diagnostic of renal tubule cell injury and renal failure. NGAL detection is also a useful marker for monitoring the nephrotoxic side effects of drugs or other therapeutic agents.

A method and kit for detecting the early onset of renal tubular cell injury, utilizing NGAL as an early urinary biomarker. NGAL is a small secreted polypeptide that is protease resistant and consequently readily detected in the urine following renal tubule cell injury. NGAL protein expression is detected predominantly in proximal tubule cells, in a punctate cytoplasmic distribution reminiscent of a secreted protein. The appearance NGAL in the urine is related to the dose and duration of renal ischemia and nephrotoxemia, and is diagnostic of renal tubule cell injury and renal failure. NGAL detection is also a useful marker for monitoring the nephrotoxic side effects of drugs or other therapeutic agents.

The invention discloses a low-intensity pulse ultrasound-assisted rotary tubular cell / tissue culture system. The Lipus-assisted rotary tubular cell / tissue culture system comprises a culture main body provided with a rotating shaft, wherein an air chamber is sheathed outside the culture main body, the rotating shaft is arranged at both ends of the air chamber, one end of the culture main body is provided with an Lipus ultrasound instrument, the ultrasound transmitting probe of the Lipus ultrasound instrument is inserted into the culture main body, and the inner wall of the air chamber is provided with an oxygen concentration controlling part. The culture system can realize on-line oxygen supply and liquid supply, thereby being beneficial to the transport of oxygen, carbon dioxide and metabolin in the system and being capable of accurately controlling the oxygen concentration. By using the Lipus ultrasound instrument as an auxiliary means, the invention creates a favorable microenvironment for the proliferation or differentiation of cells or tissues, ultimately simulates the micro-gravity environment for carrying out three-dimensional dynamic culture, and can realize functions of oriented amplification and induced differentiation.

Composite joint for fitting at least one external member to a sandwich panel and panel integrating at least one such joint.To permit the transmission of static and / or dynamic stresses between at least one external member and a sandwich panel, into said panel is integrated at least one composite joint (10). Said joint comprises a plurality of juxtaposed, elementary, tubular cells (12), oriented in the panel thickness direction, as well as at least one stress introduction cell (12a), in which is fitted a rigid part (14) for fixing the external member. The tubular cells (12) comprise composite walls formed from braided fiber roves and resin.

The present invention concerns bioactive renal cell populations, in particular a B2 cell population comprising an enriched population of tubular cells and wherein the renal cell population is depleed of a B1 cell population, renal cell constructs, and methods of screening test agents using the bioactive renal cell populations.

There is provided a method of differentiating an induced pluripotent stem cell (iPSC) into a renal proximal tubular cell (PTC)-like cell. The method comprises culturing an undifferentiated iPSC in a renal epithelial cell culture medium in the presence of one or more extracellular matrix (ECM) molecules, bone morphogenic protein 2 (BMP2) and bone morphogenic protein 7 (BMP7), for a period of from about 8 to about 10 days, under conditions sufficient to induce differentiation of the iPSC into a PTC-like cell. A cell population of differentiated PTC-like cells is also provided, as well as uses and methods of use of the cell population.