47results about How to "Prolong the duration of action" patented technology

The invention discloses a making method of Asiluowei macromolecular gel dressing, which comprises the following steps: dissolving N, N'-methylene diacrylamide into acroleic acid completely to obtain solution A; dissolving Asiluowei powder into sodium hydroxide solution to obtain solution B; dissolving polyvinyl alcohol solution, glycerin, potassium persulfate solution and water completely to obtain solution C; dripping solution A into solution B to react; adding solution C; stirring evenly; pouring into mould; heating to polymerize and crosslink to obtain the product to treat herpes zoster.

The invention discloses a targeted liposome drug delivery system, the drug delivery system is composed of a targeting ligand modified liposome entrapped hardener, and the targeting ligand is hyaluronic acid. The hardener used in the invention is a water-soluble small molecule drug, and the liposome membrane material is prepared from lecithin, cholesterol and distearoyl phosphatidyl ethanolamine-polyethylene glycol-targeting ligand in a mass ratio of (30-32): (7-9): 1. The liposome has a phospholipid bilayer, is self-closed in structure, can entrap a hardener inside the liposome, has good stability, and can prevent water-soluble drugs from being rapidly degraded and reduce the release speed of the drugs. In addition, hyaluronic acid is used for modifying the drug-loaded liposome, so targeted transportation of the drug in lymphangial malformation pathological tissues can be realized.

The invention discloses an antibacterial formaldehyde-free UV blockboard and a preparation technology thereof. The blockboard comprises a base material, an antibacterial layer and a UV curing layer which are sequentially arranged, wherein the antibacterial layer contains formaldehyde removing and bacteria resisting microspheres; each formaldehyde removing and bacteria resisting microsphere comprises a nanometer polymer hollow microsphere of which the center is permeated by water-in-oil droplets; each water-in-oil droplet comprises bamboo vinegar liquid at the outer layer, and a sodium hydroxide water solution at the inner layer; and titanium dioxide aerosol particles are dispersed in the sodium hydroxide water solutions. According to the antibacterial formaldehyde-free UV blockboard, the bamboo vinegar liquid is capable of absorbing volatile harmful gas such as formaldehyde and has spectral sterilizing efficiency to bacteria and fungus; the sodium hydroxide water solutions at the innerlayers are capable of quickly catching formaldehyde; the titanium dioxide aerosol particles are capable of oxidizing formaldehyde molecules caught by the sodium hydroxide water solutions; the water phase and the oil phase are coordinately matched with each other to continuously clean volatile harmful gas such as formaldehyde, and thus harmful bacteria and fungus can be continuously exterminated and inhibited.

The invention discloses a preparation method of a compound agent for prevention and treatment of astragalus powdery mildew. The compound agent comprises the following components by weight: 40-60 partsof a glycolysis solution, 3-8 parts of a surfactant, 0.1-1 part of rosmarinic acid, 0.1-1 part of chitosan, and 0.02-0.04 part of tetrabutyl titanate. The invention has the beneficial effects that: because of the interaction of chitosan and tetrabutyl titanate in the above-mentioned compound agent, the compound agent can form a very thin film on astragalus leaves after use, thus prolonging the action time of the compound agent; rosmarinic acid can improve the killing power of active ingredients in the glycolysis solution to astragalus powdery mildew pathogen; the surfactant can improve the compatibility of the compound agent and astragalus leaves, all the components in the compound agent have coupling effect, can effectively inhibit the spore germination and appressorium formation of astragalus powdery mildew pathogen, and affect the morphology and structure of hypha cells, thus effectively preventing and treating astragalus powdery mildew.

The invention discloses an emulsified asphalt material for purifying automobile tail gas and a preparation method thereof. The emulsified asphalt material includes the following raw material components in parts by weight: base asphalt: 100 parts; first surfactant: 1-10 parts; water: 10-60 parts; asphalt modifier: 1-20 parts; Modified porous carbon material: 1 to 20 parts; the asphalt modifier is based on lanthanide metal oxides as a carrier, and transition metal oxides as catalytic active components; the amount of transition metal is the mass of lanthanide metal oxides 5% to 100% of that; the modified porous carbon material is a porous carbon material modified by the second surfactant. The emulsified asphalt material of the present invention is mainly used for the maintenance of expressway asphalt pavement, wherein the asphalt modifier in the emulsified asphalt material has the function of purifying the automobile exhaust pollutants on the road surface, and can be Car exhaust is purified.

The invention discloses NGF and hydroxypropyl-beta-cyclodextrin inclusion compound ophthalmic gel and a preparation method thereof.The ophthalmic gel comprises NGF, hydroxypropyl-beta-cyclodextrin and an ophthalmic gel base material, wherein the content of NGF is 30-400 micrograms / ml, the content of hydroxypropyl-beta-cyclodextrin is 10-80 g / ml, and the remaining constituent is the ophthalmic gel base material.The preparation method comprises the steps of mixing NGF, hydroxypropyl-beta-cyclodextrin and the ophthalmic gel base material with water, and conducting stirring, so that gel is formed; adjusting the pH value to 6.5-8.5, adding sufficient water, adjusting the concentration of NGF to 30-400 micrograms / ml, and stirring the mixture to be uniform, so that the NGF and hydroxypropyl-beta-cyclodextrin ophthalmic gel is obtained.The ophthalmic gel has the advantages of being good in biocompatibility, good in medicine stability, low in irritation, high in medicine atrium permeability and the like.

This application relates to the technical field of medical devices, and provides a method for preparing a drug-coated balloon catheter. The method uses the three-dimensional balloon catheter obtained by inflating treatment as a raw material, and sequentially adopts the methods of ultrasonic atomization spraying and fumigation crystallization treatment. treatment to form crystals attached to the three-dimensional balloon catheter. This preparation method can reduce the loss rate of drugs during the intervention process and ensure that more drugs are used for treatment; at the same time, it improves the release rate of drugs so that drugs can quickly act on cells Improve the retention time of the drug in the body, make the drug act on the cells for a long time, reduce the metabolic rate of the drug, promote the absorption of the drug, and achieve a long-term therapeutic effect. At the same time, the preparation method has easy-to-obtain materials, is simple and easy to operate, has clear steps, and is favorable for wide application.