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120 results about "Ophthalmic Gel" patented technology

LOTEMAX (loteprednol etabonate ophthalmic gel) 0.5% contains a sterile, topical corticosteroid for ophthalmic use. Loteprednol etabonate is a white to off-white powder.

Ophthalmic bacterial-infection resisting medicine for external use

ActiveCN101766628AGood intraocular penetrationInhibit or kill growthAntibacterial agentsSenses disorderDiseaseSide effect
The invention provides ophthalmic bacterial-infection resisting medicine for external use. Linezolid is adopted as medicative raw materials to prepare eye drops, ophthalmic gel and eye ointments. The content of the linezolid in every 100 parts by weight of a medicament is within 0.1 to 1.0 parts by weight. The medicine is for external use at partial positions of eyes, and has good intraocular penetrability and mild toxic as well as side effects; moreover, the medicine is suitable for treating as well as preventing bacterial infection at partial positions of the eyes, including diseases of conjunctivitis, keratitis, keratohelcosis, iritis, ocular traumas, chemical injuries, ophthalmic postoperative infections and the like.
Owner:GUANGDONG WHOLEWIN TECH

Ganciclovir ophthalmic gel and its prepn. method

An eye gel of Ganciclovir for treating viral keratitis is proportionally prepared from ganciclovir and eye gel matrix through mixing Ganciclovir, eye gel matrix and water, stirring, regulating pH value, adding water, stirring and sterilizing.
Owner:湖北科益药业股份有限公司

Alficetin in situ forming eye gel

The invention discloses a chloramphenicol eye ophthalmic gel and a preparation method thereof; every 1000ml of the chloramphenicol eye ophthalmic gel contains 5-50g of chloramphenicol, 0.05-1g of preservative, 1.0-7.5g of osmoregulation agent, 30-150g of gel stroma, and rest amount of acid-base buffering agent and water used for injection. Due to the optimization and technique improvement of the auxiliary materials, the medicine dosage forms of the chloramphenicol are enriched, detention time of the medicine in the eyes are greatly prolonged, and the medicine can exert the drug effect, thus not only improving healing efficacy, but also reducing the times and days for taking medicine, decreasing the part side effect of the medicine and the untoward effect caused by the whole body absorption, as well as having no pessimal stimulation response.
Owner:肖正连

Gel for eye containing bromfenac sodium hydrate and preparation thereof

The invention relates to an ophthalmic gel containing the active ingredient of bromfenac sodium hydrate and a preparation method thereof; the bromfenac sodium hydrate ophthalmic gel contains the active ingredient of bromfenac sodium hydrate, macromolecular hydrogel substrate, osmotic pressure regulator, bacteriostat, antioxidant, metal ion chelating agent, pH regulator and water for injection; the ophthalmic gel has convenient application and quick effect; particularly, the gel possesses certain viscosity and can stay in the eyes for a long time, thus overcoming the defect that eye drops can only stay in the eyes for a short time after being diluted by tears and achieving more effective therapeutic effect.
Owner:ZHEJIANG SHENGBOKANG PHARMA CO LTD

Ophthalmic gel composition

The invention discloses an ophthalmic gel composition. Each gram of the composition comprises necessary components of: 1000 to 100000 IU (international unit) of epidermal growth factors (EGF), 0.5 to 3.5 mg of hyaluronate sodium, and rest components of pharmaceutical acceptable carriers. The invention also discloses a preparation method and a purpose of the composition.
Owner:SHANGHAI HAOHAI BIOLOGICAL TECH

Method for separating and/or detecting levofloxacin and methylparaben in levofloxacin hydrochloride ophthalmic gel

The application discloses a method for separating and/or detecting levofloxacin and methylparaben in levofloxacin hydrochloride ophthalmic gel. The method is a high performance liquid chromatography, and concretely comprises the following steps: preparing a test solution and a reference solution; using octadecyl silane bonded silica gel as a chromatographic column, wherein chromatographic separation test conditions are as follows: the column temperature is 30-40 DEG C, the flow velocity of a mobile phase is 0.9-1.3mL/min, and the ultraviolet detection wavelengths of the levofloxacin and the methylparaben are respectively 240-260nm and 280-300nm; detecting: respectively and precisely absorbing 10mu L of the test solution and 10mu L of the reference solution, injecting into a high performance liquid chromatograph, and reading the chromatographic peak areas of the levofloxacin and the methylparaben in the test solution. The method can accurately and rapidly measure the contents of the levofloxacin and the methylparaben in the levofloxacin hydrochloride ophthalmic gel at the same time, thus providing guarantee for the quality controllability of the levofloxacin hydrochloride ophthalmic gel.
Owner:湖北远大天天明制药有限公司

Palmatine ophthalmic gel and preparation method thereof

The invention relates to palmatine ophthalmic gel and a preparation method thereof. The method comprises the following steps: adding water for injection into a matrix and an antioxidant in a formula dosage, mixing, swelling or dissolving; adding a pH regulator for uniformly stirring, thereby obtaining a matrix liquid; weighing palmatine according to the formula dosage, adding the water for injection for dissolving, adding a preservative and an isoosmotic adjusting agent, uniformly mixing, adding the mixture into the matrix liquid, adding the water for injection to 1L, uniformly shaking, filtering by virtue of a micro-aperture filter membrane, sterilizing, and split charging, thereby obtaining the product. The gel comprises the following components: 0.5-30g of palmatine, 0.1-30g of a matrix, 0.1-20g of a pH regulator, 1-100g of an isoosmotic adjusting agent, 0.01-8g of a preservative and 0.02-5g of an antioxidant. Compared with palmatine liquid type eye drops, the product disclosed by the invention has certain advantages in the dosage form, the administration frequency can be reduced, loss of the medicine in the eyes is avoided, and the effect of the medicine for treating conjunctivitis and keratitis can be obviously improved.
Owner:昆明振华制药厂有限公司

Sodium paeonolsilate ophthalmic preparation

The invention discloses a sodium paeonolsilate ophthalmic preparation, which is prepared by adding ophthalmic preparation pharmaceutic adjuvants into sodium paeonolsilate, wherein the weight percentage of the contained sodium paeonolsilate is 0.01 to 30 percent; the balance is auxiliary materials for the ophthalmic preparation; the sodium paeonolsilate ophthalmic preparation contains eye drops, ophthalmic lipidosome, inclusion compound eye drops, eye ointment, ophthalmic gel, in-situ gel, ophthalmic liposome gel, ophthalmic injection, ophthalmic lipidosome injection and the like. The sodium paeonolsilate is used as the active effective ingredients; the ophthalmic preparation pharmaceutic adjuvants are added for preparation according to a conventional preparation method. The sodium paeonolsilate is prepared into ophthalmic medicine; the effective absorption of the medicine is enhanced; the medicine stability is improved; the retention time in the eyes can be prolonged; the toxic and side effects of the medicine are reduced; the eye bioavailability of the medicine is improved. The preparation method provided by the invention has the advantages that the process is feasible; the quality is controllable; wide industrialization prospects are very wide.
Owner:JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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