34 results about "Anaerobic infection" patented technology

Disclosed are methods and compositions for increasing tissue oxygen levels by administration of superoxygenated compositions of tissue surfaces. The methods are applicable to treatment of a wide variety of conditions including burns, bedsores, ulcers, necrosis and anaerobic infections.

This invention provides wound healing systems, which delivers oxygen to the wound bed and applies negative pressure thereto, where the source of oxygen and negative pressure are simultaneously applied to distal sites of the dressing. Methods of treating wounds and methods of treating or preventing anaerobic infection of wounds using such systems are described.

The instant invention relates to novel prodrugs of optically pure benzoquinolizine-2-carboxylic acid and pharmaceutical compositions that include the prodrugs. In particular, the present invention relates to the sulfonic acid salts of L-alanine and L-valine prodrugs of S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid. The compounds and compositions of the invention can be used to treat bacterial Gram-positive, Gram-negative and anaerobic infections, especially infections caused by resistant Gram-positive organism and Gram-negative organism, mycobacterial infections and emerging nosocomial pathogen infections.

The invention discloses a vacuum sealing washing and drainage wound surface cover device. The vacuum sealing washing and drainage wound surface cover device comprises two adhesive cover films and two medical sponge blocks, each adhesive cover film is composed of an adhesive semi-transparent film and an adhesive PE film, a zipper bone is arranged at the port of each adhesive PE film, a clamp zipper head is arranged between two zipper bones, the adjacent ends of the two medical sponge blocks are connected through a connecting wire, a vacuum pipe and a washing pipe are arranged in each medical sponge block, a nest is arranged in the surface of each medical sponge block in contact with the wound surface, each vacuum pipe is provided with a plurality of vacuum holes, and each washing pipe is provided with a plurality of washing holes. The vacuum sealing washing and drainage wound surface cover device is convenient to open and close the wound surface cover films and sponge at any time to timely observe the wound surface situation; the vacuum sealing washing and drainage wound surface cover device is convenient to place antibiotic sustained-release particles, wash the wound surface and perform anti-infection treatment; the vacuum sealing washing and drainage wound surface cover device is convenient to create an aerobic environment for the wound surface and treat anaerobic infection.

The invention relates to an amino acid salt of S-Ornidazole phosphate, especially its monoamino acid salt. With a structural formula as shown in general formula I, the amino acid salt of S-Ornidazole phosphate is mainly used for treating anaerobic infections or protozoan infections.

The invention provides compound sulfa-nitazoxanide soluble powder for pigs and poultry. The soluble powder is prepared from the following components: 20-30g of sulfa-drugs, 4-10.0g of TMP sodium, 1.5-5g of nitazoxanide, 5-25g of a co-solvent and 1-7.5g of a stabilizing agent, and the total amount after the components and auxiliaries are mixed is 100g. The soluble powder can be used for overcoming the defect that sulfa-drugs are invalid to anaerobic bacteria during infection of coccidium mixed with anaerobic bacteria, has excellent effects in preventing and treating protozoon infection and mixed infection of protozoon and bacteria of pigs and poultry, and is valid to drug-resistance coccidium infection which is poor or invalid to sulfa-drugs; nitazoxanide has the defects of water insolubility and alkali solubility, while the co-solvent can be used for improving the water solubility of nitazoxanide, and the stability of nitazoxanide can be improved by adding the stabilizing agent. The compound sulfa-nitazoxanide soluble powder is administrated by drinking, is convenient to use, and has excellent effects on preventing and treating protozoon infection and mixed infection of protozoa and bacteria of pigs and poultry.

The invention discloses a nano emulsion for treating anaerobic infections of intestinal tracts of livestocks. The nano emulsion comprises the following raw materials in percent by mass: 0.1-8.0 percent of linaloe oil, 0.1-7.0 percent of carvacrol, 0.01-0.7 percent of metronidazole, 19.0-35.0 percent of surfactant, 0-5.0 percent of cosurfactant and the balance of distilled water, wherein the sum of the mass percent of the raw materials is 100 percent. The nano emulsion has stronger inhibiting and killing functions to most of obligate anaerobes, and is mainly used for treating enteritidis caused by infections of anaerobic bacteria such as bacteroides, clostridium, aerogenesis bacillus, peptococcus, eubacteria and streptococcus faecalis, for the livestocks. The nano emulsion has the advantages of high bioavailability, remarkable antibacterial action and treatment effect, and wide market prospect in the field of veterinary medicines.

The invention discloses a preparation method and applications of gastric floating tablets containing ornidazole, belonging to a novel technical field of medicament and relating to a novel medicament form of ornidazole. 1. The gastric floating tablets are used to treat a plurality of diseases caused by bacteroides fragilis, bacteroides distasonis, bacteroides oval window, etc.; (2) oral cavity infections: pericoronitis, periapical periodontitis, pericoronitis, acute ulcerouse gingivitis etc.; (3) gynae infections: endometritis, myometritis, oviduct or ovarian abscess, pelvic cavity soft tissue infection, haemophilis vaginitis etc.; (4) surgical infections: wound infection, abscess of epidermis, bedsore ulcerouse infection, cellulites, gas gangrene etc.; (5) brain infections: meningitis, brain abscess; (6) septicaemia and severe general infections etc. 2. The gastric floating tablets are used to prevent infections before an operation and treat anaerobic infections after an operation. 3. The gastric floating tablets are used to treat urogenital canal trichomonas and giardia lamblia infections, such as trichomoniasis etc. 4. The gastric floating tablets are used to treat alimentary system amebiasis, such as amebic dysentery, amoebic liver abscess etc. The new medicament form is characterized in that the surface thereof is hydrated into gel after contacting with gastric juice at body temperature so as to cause volume expansion because the gastric floating tablets contain a plurality of hydrophilic macromolecule materials. Weight of the tablets is less than floating force of the gastric juice, so the tablets float on the gastric juice so as to prolong time in a stomach.

The invention provides a toothpaste for cats, which belongs to the technical field of daily necessities for animals. The toothpaste for cats is mainly prepared from the following raw materials: water, lotus leaf extract, hawthorn leaf extract, catnip extract, glycerin, salmon oil, taurine, notoginseng powder, xylitol, vitamin C, Vitamin B2, metronidazole. The present invention further discloses a preparation method of cat toothpaste. The catnip extract of the present invention is attractive to cats and reduces the cat’s resistance to tooth cleaning. In addition, the present invention does not contain alcohol and other ingredients harmful to cats, and the lotus leaf extract and hawthorn leaf extract contain Flavonoids have a good antibacterial effect on pathogenic bacteria that cause gingivitis, periodontitis, bad breath and gum redness, can keep cats' breath fresh and effectively solve cat gum problems, and can also remove dental calculus and dental plaque. Oral infections are mostly caused by anaerobic bacteria, and metronidazole has a strong inhibitory effect on them, and it is not easy to develop drug resistance.

The invention provides compound sulfa-nitazoxanide soluble powder for pigs and poultry. The soluble powder is prepared from the following components: 20-30g of sulfa-drugs, 4-10.0g of TMP sodium, 1.5-5g of nitazoxanide, 5-25g of a co-solvent and 1-7.5g of a stabilizing agent, and the total amount after the components and auxiliaries are mixed is 100g. The soluble powder can be used for overcoming the defect that sulfa-drugs are invalid to anaerobic bacteria during infection of coccidium mixed with anaerobic bacteria, has excellent effects in preventing and treating protozoon infection and mixed infection of protozoon and bacteria of pigs and poultry, and is valid to drug-resistance coccidium infection which is poor or invalid to sulfa-drugs; nitazoxanide has the defects of water insolubility and alkali solubility, while the co-solvent can be used for improving the water solubility of nitazoxanide, and the stability of nitazoxanide can be improved by adding the stabilizing agent. The compound sulfa-nitazoxanide soluble powder is administrated by drinking, is convenient to use, and has excellent effects on preventing and treating protozoon infection and mixed infection of protozoa and bacteria of pigs and poultry.