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Wound healing device

a wound healing and wound technology, applied in the field of wound healing systems, can solve the problems of long-term trouble, inability to heal wounds, etc., and achieve the effect of reducing pain, reducing pain, and reducing pain

Inactive Publication Date: 2011-06-02
TOPAZ
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0014]In one embodiment, this invention provides a method of treating a wound in a subject, said method comprising the steps of applying a source of oxygen containing to a wound in said subject and concurrently applying negative pressure to said wound, wherein said source of oxygen maintains wound atmospheric oxygen at a value of at least 21% of the total gas in said source and whereby application of oxygen and negative pressure to said wound stimulates wound healing.
[0023]concurrently or temporally applying oxygen to said second inlet;whereby application of oxygen and negative pressure to said wound treats or prevents anaerobic infection of said wound or whereby application of oxygen and negative pressure to said wound stimulates wound healing.

Problems solved by technology

The treatment of open wounds that do not spontaneously close has long been a troublesome area of medical practice.
Of those, necrotizing soft-tissue infections (NSTIs) are infrequent but highly lethal infections.
Superficial nerves are damaged, producing the characteristic localized loss of sensation.
Pathogenesis of NF is rapid and can lead to loss of an associated limb or life.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

Application of Henry's Law

[0134]The partial pressure of a gas in a mixture of ideal gases is defined as the pressure which the gas would have if it alone occupied the volume. The total pressure of a gas mixture is the sum of the partial pressures of each individual gas in the mixture. The partial pressure of a gas dissolved in a liquid is the partial pressure of that gas which would be generated in a gas phase in equilibrium with the liquid at the same temperature. The partial pressure of a gas is a measure of thermodynamic activity of the gas's molecules. Gases will always flow from a region of higher partial pressure to one of lower pressure; the larger this difference, the faster the flow. Gases dissolve, diffuse, and react according to their partial pressures, and not necessarily according to their concentrations in a gas mixture.

[0135]The solubility of a gas in a liquid solution is affected by temperature and by the partial pressure of that gas over the liquid as was formulated...

example 2

[0137]Application of an Embodied Device of this Invention

[0138]An in-vitro model was designed, to assess oxygen behavior in a simulated wound atmosphere. An experimental setup was planed to determine the spectrum levels of oxygen partial pressures in the environment of wounds treated with RNPT and RNPT simultaneously enriched with oxygen under various oxygen flow conditions and varied application of negative pressure.

[0139]The system utilized is depicted in FIG. 8. The system combines application of a regulated oxygen-enriched atmosphere with RNPT. A phantom leg was circumferentially draped with Polyvinyl chloride (IUPAC Polychloroethene) foam and was sealed under a drape covering the entire treated area. The system affords a relatively large volume cavity, necessitating a high flow vacuum pump to accommodate the cavity volume and the high inflow volume of oxygen, easily achieved by connecting the apparatus to a wall suction outlet as a sub atmospheric source.

[0140]Negative pressure...

example 3

[0145]Peripheral arterial disease (PAD) causing arterial insufficiency is the most important factor relating to the outcome of a diabetic foot ulcer. The prevalence of PAD in people with diabetes is probably high, and ranges from 10% to 40% depending on the definition used; in patients with foot ulcers approximately 50% have signs of PAD.

[0146]Critical ischemia indicates risk of amputation of a major part of the limb. Chronic critical ischemia is currently defined by either of the two following criteria: persistent ischemic rest pain requiring regular analgesia for more than two weeks; ulceration or gangrene of the foot or toes—both associated with an ankle systolic pressure of <50 mmHg or a toe systolic pressure of <30-50 mmHg. The most widely used method for the diagnosis and quantification of PAD is the measurement of ankle pressure.

[0147]The external application of a vacuum dressing in such patients, however, may cause perfusion impairment of the distal limbs due to the pressure...

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PUM

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Abstract

This invention provides wound healing systems, which delivers oxygen to the wound bed and applies negative pressure thereto, where the source of oxygen and negative pressure are simultaneously applied to distal sites of the dressing. Methods of treating wounds and methods of treating or preventing anaerobic infection of wounds using such systems are described.

Description

FIELD OF THE INVENTION[0001]This invention provides wound healing systems, which comprise dressings; which may be composed of at least two layers, which include a first absorptive and / or conductive and a second fluid impermeable layer and which system delivers oxygen to the wound bed and applies negative pressure thereto, where the source of oxygen and negative pressure are simultaneously applied to distal sites of the dressing. The system may comprise a fluid trap for collection of conveyed fluid and / or debris, which may further comprise a sensor for detection of changes in fluid volume or characteristics, a sensor to detect local pressure at the wound and distal limb, a controller to regulate differential vacuum levels and a means to regulate and synchronize application of negative pressure and oxygen. The invention is further directed to the application of oxygen and negative pressure wounds for use in treating such wounds, or treating or preventing anaerobic infection of such wo...

Claims

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Application Information

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IPC IPC(8): A61M37/00
CPCA61F2013/0017A61F2013/00174A61M1/0084A61M35/00A61M2202/0208A61M2205/15A61M1/0088A61M2205/3389A61M2205/84A61M2205/33A61M1/73A61M1/75A61M1/74A61M1/85A61M1/915A61M1/96A61M1/94A61M1/916A61M1/982A61F13/01038A61F13/01029A61F13/05A61M35/30A61P17/02A61M1/918A61M1/95
Inventor TOPAZ
Owner TOPAZ
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