126 results about "Trichomonas" patented technology

A vaginal treatment composition that employs a therapeutic agent to inhibit and / or treat vaginal infection is provided. The therapeutic agent is capable of inhibiting and / or killing Gardnerella (e.g., Gardnerella vaginalis), Candida (e.g., Candida albicans), and / or Trichomonas (e.g., Trichomonas vaginalis) pathogens. Desirably, such antimicrobial efficacy is achieved without substantially inhibiting the growth of Lactobacillus acidophilus. For instance, sugars and / or sugar alcohols may be employed in the present invention as a therapeutic agent for inhibiting and / or treating vaginal infection. In one particular embodiment, D-xylitol is used as the therapeutic agent.

The invention relates to a test paper tape which can be used in the gynecological multiprogramming dry-chemistry joint detection. The test paper tape provided by the utility model comprises a dry-chemistry multiprogramming detection test paper tape which consists of a plastic substrate tape and various solidified regent blocks, and sample diluent. The dry regent blocks include combinations formed by increasing or decreasing at least three or more regent blocks of a Ph test regent block, a lactic acid regent block, a hydrogen peroxide concentration regent block, a leukocyte esterase concentration regent block, a neuraminidase activity regent block, an amine test regent block, a proline aminopeptidase substrate reagent block, an oxidase substrate reagent block, a N-acetylamine hexosidase substrate reagent block, a trichomonas specific protease substrate hydrolysis reagent block. the gynecological multiprogramming dry-chemistry joint detection test paper test provided by the utility model can detect Ph, lactic acid, hydrogen peroxide, leukocyte esterase, neuraminidase, amine test, proline aminopeptidase, oxidase, N-acetylamine hexosidase and trichomonas specific protease which are contained in leucorrhea sample at the same time, and can accurately reflect the microorganism environment of a women reproductive tract, the cleanness of leucorrhea secretion and the conditions of Candida albicans, trichomonas, gonococcus and the pathogens of bacterial vaginosis, thereby making the gynecological trichomonas detection more comprehensive; besides, the test paper tape provided by the utility model can be used easily and conveniently, and results can be obtained quickly. If the test paper tape is used together with a gynecological dry-chemistry analyzer, the operation can become easier and the result can be obtained more quickly.

The invention discloses a drug for treating gynecologic and andrological diseases and a preparation method thereof; calculated according to the portion by weight, the drug is prepared by taking 65 portions to 100 portions of sophora flavescens, 40 portions to 70 portions of radix stemonae, and 40 portions to 70 portions of cortex dictamni as the basic raw materials, and can also be compatible with 40 portions to 70 portions of frutus cnidii and 40 portions to 70 portions of broom cypress fruit. Compared with the prior art, the drug provided by the invention is prepared by the refining of natural Chinese medicinal herb compositions and is combined with modern advanced preparation technology; the prepared product has the functions of clearing away heat and toxic materials, killing insects and removing dirties, relieving swelling and pain, and removing dampness and stopping itching, plays the roles of obviously resisting bacteria, diminishing inflammation, stopping itching, and relieving pain, has good therapeutic effect to fungal, trichomonas, non-specific vaginitis, and can also be used for men scrotum eczema, anal fissure hemorrhoid pain and daily scrotum and anus cleaning; and the drug is safe without toxic and side effects, is not easy for producing drug resistance, is convenient for use and carryover, and has comfortable feeling after the use, thereby leading the patients to be willing to accept the drug.

The release by trichomonads of a hydrolase that hydrolyzes a narrowly defined class of substrates at a low pH without interference from hydrolases that are unrelated to trichomoniasis is the basis for a selective diagnostic assay for trichomoniasis that measures hydrolysis of any of these substrates by vaginal fluid at a low pH. Selective assays for trichomoniasis are also obtained by removing particulate matter from a sample of vaginal fluid to extract a fraction devoid of particles greater than a selected size, and where desired, combining the extracted fraction with any of certain specified hydrolase inhibitors, then testing the fraction for enzymatic hydrolase activity. These qualities of trichomoniasis are the basis for a series of diagnostic tests and test devices that produce results that are detectable by visual and other means with a high degree of accuracy.

The invention relates to the technical field of antibacterial gel, in particular to chitosan antibacterial gel and a preparation method thereof. Each liter of the chitosan antibacterial gel comprises the following raw materials by weight: 5-30g of modified chitosan, 2.5-10g of carbomer, 1-1.8g of alum, 2-40g of glycerol, 0.3-10g of lactic acid, 0.1-0.8g of menthol and 2-8g of sodium carboxymethylcellulose. The chitosan antibacterial gel which is good in curative effect, can be used for preventing relapse of inflammation and is harmless to human body is prepared by using the synergistic effect of modified chitosan serving as a major raw material as well as carbomer, alum, glycerol, lactic acid and sodium carboxymethylcellulose serving as auxiliary materials, and is suitable for preventing, treating and nursing various vaginal bacterial infections, trichomonas infections, mixed infections, vulvitis, leucorrhea, candidal infection as well as wound infections of cervix uteri, genital tract and mucous membrane. By using the chitosan antibacterial gel, wound healing after physical treatment of cervical erosion is promoted, and nursing of vaginal dryness as well as cross infections in sexual intercourse and the like is improved.

The invention aims to provide a combined detection kit for vaginitis, capable of evaluating vaginal micro-ecological environment, vaginal cleanliness, and pathogens of bacterial vaginosis, Candida vaginitis, trichomonas vaginitis of the tested person simultaneously. Ihe following technical scheme adopted by the invention, a combined detection kit for vaginitis is provided and comprises a reaction device, diluent and chromogenic liquid, the reaction device is a hole type box-shaped reaction device with six reacting blind holes, in which a hydrogen peroxide concentration detection reagent pad, a leukocyte esterase detection reagent pad, a neuraminidase detection reagent pad, a proline aminopeptidase detection reagent pad, an acetyl glucosaminidase detection reagent pad and pH detection test paper are arranged respectively. Through the combined detection, the vaginitis caused by most of the BV (Bacterial Vaginosis) pathogens, the Candida albicans and the trichomonas can be detected, BV missing detection caused by the simple detection for one kind of enzyme activity is avoided largely, and the detection reliability and accuracy are increased.

The invention discloses external lotion for treating gynecological inflammation and a method for preparing the same. Fructus cnidii, pepper, swamp mahogany leaf, yellowweed, radices sophorae flavescentis, fructus kochiae, rhizoma smilacis glabrae, phellodendri, and other medicine materials are subjected to extraction and processing to prepare the external lotion. The external lotion clears heat, removes dampness, dispels wind, and arrests itch. The external lotion is used for treating downward flow of damp heat, pruritus genitalium, or burning pain, and more vaginal discharge which has yellow color, is like pus, is red alternate with white or is of yellow bubble shape; and the external lotion is also used for treating mycotic, trichomonas, and nonspecific vaginitis and episioitis as the above symptoms.

The present invention relates to preparation of a new medicine Nifuratel nysfungin vagina tablet for gynecologic antisepsis and anti-inflammation. Nifuratel nysfungin can play a more complete role in curing mixed vagina infection (candida, trichomonas and bacteria) and pathogen which can not be or can not be timely and clearly diagnosed and preventing mildew secondary infection and recurrence after the treatment of other medicines. The present invention can be used for curing bacterial vaginopathy, trichomonas vaginitis, monilial vulvovaginitis, and vagina mixed infection. The advantage of the present invention lies in that the added pH buffer system ensures pH of the medicine is within 3.5 to 4.0 close to the physiological pH of vagina, thus effectively protecting the physiological environment of vagina, providing the appropriate living conditions beneficial to flora in vagina and promoting the recovery of diseases.

The invention discloses a poultry and livestock feces deodorant for farms, which relates to the technical field of poultry and livestock breeding, and is made of the following raw materials in parts by weight: 20-25 parts of eucalyptus leaves, 15-20 parts of phoenix leaves, and 10-20 parts of sawdust ash 15 parts, 10‑15 parts of cypress leaves, 8‑12 parts of capillary, 6‑10 parts of modified attapulgite, 6‑10 parts of zeolite powder, 5‑8 parts of sepiolite powder, 5‑8 parts of rapeseed meal, 5-8 parts of distiller's grains, 4-6 parts of pine needle powder, 3-5 parts of wormwood, 2-3 parts of alum, 1-2 parts of borax, and 1-2 parts of chili seed powder. The present invention uses plant components, food waste and minerals as raw materials to prepare a poultry manure deodorant for farms, which not only reduces the treatment cost, but also has a significant deodorizing effect, starting from two aspects of neutralization and adsorption, and the added part The auxiliary materials have excellent bactericidal and insecticidal effects, and the treated feces can be used for planting or aquaculture to realize the rational utilization of resources.

A region of the Trichomonas vaginalis AP65-1 gene has been identified which is useful for performing amplification assays to determine specifically whether T. vaginalis is present in the sample being tested. Oligonucleotides useful for performing thermal Strand Displacement Assay (tSDA) reactions on this gene are disclosed. The disclosed oligonucleotides can be used in an assay which is specific for multiple strains of T. vaginalis and which does not show cross reactivity with the genomes of other microorganisms or with human DNA.

The present invention provides methods and compositions for diagnosing Trichomonas infection by detecting an antibody that specifically binds a Trichomonas α-actinin protein in a sample from a subject.

The invention relates to a nifuratel-nysfungin gel and a preparation method of the nifuratel-nysfungin gel. The gel is prepared by nifuratel, nysfungin, hydrogel matrix and other auxiliary materials. According to the invention, the pharmaceutical ingredients are fully dissolved and evenly mixed in the gel matrix, and the pharmaceutical ingredients are fully contacted with the vaginal wall, so that the bacteriostasis of the medicine is fully exerted, and the nifuratel-nysfungin gel is safe and comfortable to use without foreign body sensation and greasy feeling. The nifuratel-nysfungin gel canbe used for treating vulva and vaginal infections and vaginal mixed infection caused by bacteria, trichomonas and candida, thus effectively maintaining the physiological environment of the vagina, providing the survival condition suitable for vaginal beneficial bacterium group and promoting disease recovery.

The invention relates to a method for preparing a new gynecological anti-bacterial anti-inflammatory drug, namely dithiazole vaginal effervescent tablet and a method for quality control. The dithiazole vaginal effervescent tablet is used for treating gynecopathy, anorectal diseases and skin commonly-encountered diseases such as pelvic inflammatory disease, cervical erosion, vaginitis and the like caused by anaerobic bacteria, aerobic bacteria, trichomoniasis, pure or mixed fungal infections. The dithiazole vaginal effervescent tablet is characterized in that lactic acid and a calcium lactate buffer system are added to the formulation so that the pH value of the drug is between 3.5 and 4.0 similar to the vaginal physiological pH and is advantageous to remove pathogen and infusorian, provide living conditions suitable for vaginal beneficial bacterium group of lactic acid bacteria, and promote the illness rehabilitation. Besides, the dithiazole vaginal effervescent tablet uses pharmaceutical acceptable water-soluble polymer materials such as water-soluble polymer polyethylene glycol, polyvidone K30 and the like to enwrap acidic or alkaline components of an effervescent disintegrant so as to avoid the occurrence of hidden spots or even collapsing phenomenon on the surface of the tablet caused by gas production reaction resulted from small amount of water in the storage process, and uses a ethanol solution with adhesives and surface-active agents for granulation so that the hydrolysis of clotrimazole can be prevented, the infiltration of moisture is promoted in use, the uniform collapse is accelerated, and gas bubbles are homogeneous and stable.

There is provided compositions and methods to inhibit the adherence of pathogenic microorganisms to cells. The composition includes water soluble PEO / PEG polymers which may be hydrophilic or amphiphilic block copolymers. One example of a suitable composition is polyethylene glycol or polyethylene oxide with a chemical formula of H—(OCH2CH2)n-OH. Another example of a suitable composition is amphiphilic block copolymer with a chemical formula PEOm-Xp-PEOn, where PEO is —(OCH2CH2)n-O and X is PPO(—(OCH2CH2CH2)m-), or PLGA (poly(lactic-co-glycolic acid), or PMMA (polymethyl methacrylate), or PBO (polybutylene oxide). The pathogenic microorganism may be a bacterial, fungal, viral or trichomonial pathogen and the composition prevents adherence of the pathogenic microorganism in, for example, a urogenital tract of a mammal and aids in reducing malodor generation. The composition may be applied to vaginal health products like, for example, moisturizer, gel, jelly, cream, insert (tablet), ointment, foam. The composition may also be applied to a feminine hygiene product, like, for example, a tampon, feminine pad, feminine wipe or panty liners.

The present invention is directed to diagnostic devices and methods for detecting Trichomonas infections.

The present invention provides methods and compositions for diagnosing Trichomonas infection by detecting an antibody that specifically binds a Trichomonas α-actinin protein in a sample from a subject.

The invention provides a traditional Chinese medicine composite for treating chicken histomoniasis and a preparation method thereof. The traditional Chinese medicine composite comprises 10-30 parts ofcoptis chinensis, 10-30 parts of scutellaria baicalensis, 10-30 parts of golden cypress, 5-15 parts of oriental wormwood, 5-15 parts of kuh-seng, 5-10 parts of hairyvein agrimony, 2-7 parts of commoncnidium fruit, and 10-30 parts of the root of Chinese pulsatilla according to the weight pars which are prepared into oral solution by decocting and concentrating; the traditional Chinese medicine composite for treating chicken histomoniasis not only can promote histomonas meleagridis and toxins thereof to be discharged from body, but also can inhibit the growth and reproduction of polypides in the body, addresses both the symptoms and root causes of histomonas meleagridis, eases the problem to a certain degree that chicken is limited to be sold and exported owing to medicinal residue; the traditional Chinese medicinal plants are prepared into oral solution, thus omitting procedures involved in feed preparation; the preparation method thereof is simple and convenient and suitable for requirements of large-scale industrial production.

The present invention relates to disease treating nitroimidazole derivative, and the compound may be used in preparing medicine for resisting anaerobic bacteria and trichomonas.

The invention discloses aloe care lotion, which contains aloe nanosuspension liquid stock, a saussurea involucrata extract, a chamomile extract, sodium hyaluronate and a polymeric material. The preparation method comprises the following steps: putting aloe leaves into a homogenizer, and crushing and micronizing processed material particles through high-frequency strong ultrasonic cavitation action to form 1-700nm nanoparticles to obtain the aloe nanosuspension liquid stock; and stirring and mixing the obtained aloe nanosuspension liquid stock, the saussurea involucrata extract, the chamomile extract, thesodium hyaluronate, the polymeric material and a matrix to obtain the required aloe care lotion. The aloe care lotion has a unique biological slow-release function, is capable of effectively repairing and protecting vagina and wall cervix, comprehensively nourishing, and removing vaginal dryness, sufferings and discomfort caused by various reasons, has a significant inhibition function on a plurality of pathogenes capable of causing bacterial, mycotic, trichomonas, senile and mixed infection vaginitis, cervical erosion and kinds of sexually transmitted diseases, and is capable of effectively removing inflammation and preventing cross infection. The aloe care lotion is free of thrill, free of toxins or harm and free of side effects after being used.

A method and kit for detecting Trichomonas vaginalis infection in a human subject are disclosed. In the method, a body-fluid sample such as a vaginal swab sample or urine is obtained from the subject and contacted with an antibody specific against a Trichomonas adhesin peptide, forming an antibody-adhesin peptide complex if the subject is infected with Trichomonas. The presence or absence of the complex establishes, with a reliability of at least 80%, in the case of a vaginal swab sample, and with a reliability of at least 40% in the case of a urine sample, the presence or absence, respectively, of Trichomonas infection in the subject. A preferred test kit employs a dry-strip, sandwich assay, format.

The invention discloses a Chinese medicinal composition for resisting trichomonas columbae disease. The Chinese medicinal composition comprises the following components by weight portion: 30 to 50 portions of houttuynia, 30 to 50 portions of fried baikal skullcap root, 25 to 40 portions of madder root, 25 to 40 portions of purple gromwell root, 15 to 30 portions of schizonepta, and 15 to 30 portions of bupleurum root. The invention also discloses a method for preparing an oral liquid of the Chinese medicinal composition. In the method, traditional Chinese medicaments are used to replace Western medicaments such as metronidazole, which are prohibited from being used for animal products, to facilitate the production of pollution-free foods. When a pigeon infects the trichomonas columbae disease, the pigeon can be better treated if taking the Chinese medicinal composition and the curative ratio is 93.33 percent, and the effectiveness ratio is 100 percent.

The invention relates to a medicinal composition, ointment and a medicament capable of contracting a female vagina. The medicinal composition is prepared from the following active pharmaceutical ingredients in parts by weight: 1 to 2 parts of herba asari, 3 to 5 parts of lotus, 8 to 10 parts of fructus cnidii, 0.5 to 1 part of rhizoma chuanxiong, 1 to 2 parts of rhizoma gastrodiae, 3 to 8 parts of radix sophorae flavescentis, 10 to 15 parts of areca nut, 2 to 3 parts of cortex phellodendri, 3 to 6 parts of radix salviae miltiorrhizae, 8 to 12 parts of flos carthami, 12 to 15 parts of borneol, 5 to 7 parts of ginseng, 3 to 6 parts of radix angelicae sinensis, 3 to 5 parts of herba leonuri, 2 to 4 parts of costus root and 10 to 20 parts of alum. The medicinal composition, the ointment and the medicament disclosed by the invention have the beneficial effects of enhancing the elasticity of a vaginal wall in several minutes, resisting atrophy, balancing the endocrine, enabling the muscle blood flows of the whole labium, clitoris and vagina to be increased, contracting the vagina, suddenly generating sexual desire, itching eczema dampness, killing various pathogenic bacteria such as mould, trichomonad and the like, and preventing gynecological diseases.

Proguanil has been found to have rapid and effective killing activity against a variety of disease-causing micro organisms. For example, when applied topically, proguanil is particularly effective against Propionibacterium acnes, a bacteria that causes acne; Corynebacterium minutissimum, a bacteria that causes erythrasma, Gardnerella vaginalis, a bacteria that causes vaginosis; Trichomonas vaginalis, a protozoan that causes trichomoniasis and C. albicans, a fungus (a form of yeast).

The invention provides a Povidone iodine effervescent tablet for preventing and treating cow's vaginitis, which is prepared from Povidone iodine, tartaric acid, sodium hydrogen carbonate, cross bonding polyvinylpyrrolidone, miropowdered silica gel, sodium dodecylsulfate, magnesium stearate, sodium chloride or lactose through dry method palletizing and pelleting.

The present invention provides methods and compositions for detecting a Trichomonas antigen in a fixed sample and for diagnosing Trichomonas infection by detecting a Trichomonas antigen in a fixed sample.

The present invention provides methods and compositions for identifying a subject at increased risk of having prostate cancer by detecting an antibody that specifically binds a Trichomonas α-actinin protein in a sample of the subject.

The invention relates to a method for preparing novel gynecological policresulen vaginal tablet used for antisepsis and anti-inflammation and a quality control method thereof. The policresulen has broad-spectrum antibacterial effect on common gram-positive bacterium, gram-negative bacterium, fungus and some viruses, wherein, anaerobe trichomonas and monilia are particularly sensitive to the policresulen but vaginal lactobacilli flora is hardly effaced. The invention has the advantages that vagina local medication avoids or reduces possible untoward effect caused by systemic administration; highly effective concentration of the medicine on lesion site is in favor of developing therapeutic effect, effectively protecting physiological environment of the vagina and providing suitable life condition for good bacteria; wherein, prescription of 1,000 preparation units of the medicine is: 45-180g of the policresulen, 30-180g of filler lactose, 60-500g of starch, 50-500g of kaolin, 2-10g of bonding agent hypromellose, 6-50g of fluidizer silicon dioxide, 30-300g of disintegrating agent microcrystalline cellulose, 20-200g of polyvinyl polypyrrolidone and 1-10g of lubricant magnesium stearate.

The present invention relates to plant medicine and its preparation process. The medicine consists of active components with or without pharmaceutically acceptable supplementary material. The active components include the supercritical CO2 extractive, alcohol extractive or water extractive of Saussurea involucrata in 1-3 weight portions, flavescent sophora root in 2-4 weight portions, cnidium fruit in 1-3 weight portions and broom cypress fruit in 0-3 weight portions. The externally applied medicine has excellent functions of resisting bacteria, resisting inflammation and resisting trichomonas. The medicine with supercritical CO2 extracted active components has ever higher treating effect.

The invention discloses the use of a Chinese medicinal composition in treating gynaecologic diseases, wherein the composition comprises the following constituents (by weight portions): yellow-corktree bark 100-150, giant knotweed rhizome 100-150, cape jasmine 90-120, lycopus herb 100-150, hairy holly root 90-120, rhubarb horsetails 40-70, acorus gramineus soland 60-90, Clematis chinensis 60-90, evodia rutaecarpa benth 40-70, and lychee seed 40-70.