The invention relates to an
analysis method and a
system of metagenome data. According to the invention, a preliminary
species identification result of a sample is obtained on the basis of a k-Mer
algorithm, a part or all of supporting sequences are extracted on the basis of the preliminary
species identification result, and the preliminary
species identification result is verified by using a blast
algorithm to judge whether the preliminary species identification result is a reported detected species or not. The method and
system disclosed by the invention can lower
false positivity, quickly and accurately obtain the reported detected species of the sample in a short time, and are compatible with various mainstream sequencing platforms, thereby being suitable for second-generation sequencing technologies and third sequencing technologies; the method and
system of the invention can also accurately identify
drug-
resistant genes and
drug-resistant
mutation sites of the sample and map thedrug-
resistant genes and the
drug-resistant
mutation sites of the sample to the reported detected species. Furthermore, the system disclosed by the invention can be used for identifying pathogenic microorganisms, especially
endocarditis pathogens to overcome the defect that the
endocarditis pathogens are difficultly cultured.