The invention discloses a preparation method of a degradable artificial
lacrimal duct, and the clinical application of the
lacrimal duct on the treatment of lacrimal passage blockage or
dacryocystitis. The main components of the artificial
lacrimal duct comprises biodegradable I type collagen,
chitosan, and medical
polyvinyl alcohol. The I type collagen has the effect of rapidly arresting bleeding and accelerating the
wound healing, the
chitosan has the function of bacteriostasis, anti blocking and anti cicatrix, and the
polyvinyl alcohol enhances the supporting ability of the artificial lacrimal duct. The inner
diameter of the invention is 0.5 to 0.7 mm, the outer
diameter is 0.9 to 1.5 mm, for the lacrimal duct which has length larger than or equal to 20 mm, the components mixing is even, the inner surface and the outer surface are flat, thereby having good tenacity and elasticity, and being suitable for the clinical operation. After the lacrimal duct is contacted with water for 10 to 30 minutes, the water is absorbed rapidly and the invention is swelled, and the functions of mechanical locating and preventing the lacrimal duct from gliding can be realized. After the wound is healed, the lacrimal duct is gradually degraded, the degradation product can flow out from the
nasal cavity along with
tears, and the second time operation is not required to take off the degradation product, the effect of curing the blockage of the lacrimal passage is improved, and the abrasion caused by the second time operation is avoided. Chemical crosslink in a specific degree also can be performed to the lacrimal duct according to different requirements of degrading time to adjust the degrading speed inside the lacrimal passage.