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30results about How to "Help adhesion" patented technology

Calcium phosphate/collagen/bone-like apatite three-level bionic bone tissue engineering scaffold and preparation method thereof

The invention provides a calcium phosphate / collagen / bone-like apatite three-level bionic bone tissue engineering scaffold and a preparation method thereof. The material of the scaffold possesses components similar to natural bone tissues, and an inorganic / organic / inorganic three-level bionic bone-like netted three-dimensional structure. The preparation method comprises: customizing a calcium phosphate ceramic which possesses a bionic porous structure similar to the natural bone micropore structure, filling collagen prepared by simulated body fluid (SBF) into the porous calcium phosphate ceramic base, low-temperature aging to simulate a biomineralization process, in-situ nucleating on the collagen organic macro-molecule matrix, and self-assembly crystallizing to form a third level bone-like apatite layer structure. The composite scaffold material has bionic material components and bionic microstructure both similar to the natural bone tissues, the mechanical properties and the biological activity of the material are substantially improved, and the composite scaffold material has a wide application prospect.
Owner:SICHUAN UNIV

Preparation method of a mechanically enhanced cell-loaded microchannel hydrogel

The invention relates to a preparation method of a mechanically-enhanced cell-loaded microchannel hydrogel, which comprises the following steps: preparing a mixed solution of hydrogel sol and cell culture fluid, and pouring the sol-cell mixed liquid into a polymethyl methacrylate die into which capillary tubes or fibers are inserted, thereby enabling primary crosslinking; drawing out the capillary tubes or fibers, introducing the hydrogel sol into microchannels of the cell-loaded hydrogel, and reinserting the capillary tubes or fibers, or sucking excess hydrogel sol out of the microchannels and carrying out ultraviolet irradiation, thereby enabling secondary crosslinking, so that the cell-loaded hydrogel with thick hydrogel layer is formed in the wall regions of the microchannels; and drawing out the capillary tubes or fibers, introducing endothelial cell culture fluid into the microchannels of the cell-loaded hydrogel, and culturing so that the endothelial cells grow and spread to form endothelial microchannels. The introduction of the thick hydrogel layer can maintain the stability of the microchannels in the hydrogel, and prevent shedding and intrusion of the endothelial cells;and the culture fluid in the microchannels can be filtered and screened.
Owner:XI AN JIAOTONG UNIV

Bionic in-situ regeneration repair nano sticking patch and preparation method and application thereof

The invention relates to a bionic in-situ regeneration repair nano sticking patch, which is formed by overlapping an layer A with a cationic group material and a layer B with an anionic group material sequentially, wherein the sticking patch comprises 20 to 80 percent by mass of the A layer with the cationic group material and the balance of the layer B with the anionic group material; layer A with the cationic group material comprises at least one of polysaccharide with a cationic group, protein with the cationic group or opypeptide (polypeptide) with the cationic group; layer B with the anionic group material comprises at least one of polysaccharide with an anionic group, protein with the anionic group or opypeptide (polypeptide) with the anionic group; and the sticking patch comprises not more than 10 percent by mass of added functional factors and / or functional polypeptide. The raw materials used by the invention are materials which can be degraded in vitro and have biocompatibility. The sticking patch is flexible, has good tissue adhesivity, is suitable for concave-convex surfaces of visceral organs, has strong stretching resistance and air pressure resistance, is suitable for application of sticking, sealing, leak stoppage, hemostasia, isolation, repair, adhesion prevention and artificial meninges of defect tissues and can also be used as a slowly-releasing carrier of a medicament and a nano-grade tissue engineering support material.
Owner:SUZHOU BOCHUANG TONGKANG PHARM TECH CO LTD

Transformer substation porcelain bottle charged automatic cleaning robot cleaner

The invention discloses a transformer substation porcelain bottle charged automatic cleaning robot cleaner. The cleaner comprises a rack and a cleaning assembly. The cleaning assembly is mounted on the rack. The cleaning assembly comprises a mounting plate, a brush plate, a driving mechanism used for driving the brush plate to do up-down reciprocating brushing and a dust collection mechanism. Themounting plate is mounted above the rack. The brush plate and the driving mechanism used for driving the brush plate to do up-down reciprocating brushing are mounted above the mounting plate. The driving mechanism comprises a first motor, a rotary disk and a movable plate. The dust collection mechanism comprises a cylinder block, a piston, a piston rod and a dust collection tank. The transformer substation porcelain bottle charged automatic cleaning robot cleaner is provided with the cleaning assembly to drive the brush plate to move up and down to do reciprocating brushing. The piston rod drives the piston to move up and down so as to blow up dust adhering to equipment. When the piston moves downwards, the cleaner sucks blown dust into the dust collection tank through a communicating pipe, the dust collection tank and a suction pipe. The cleaning efficiency can be improved. The cleaning effect is better.
Owner:滕州市智星电力电子工程有限公司

Protein adhered to surface layers of bacteria and application thereof

The invention relates to a protein adhered to the surface layers of bacteria and an application thereof. The invention discloses an application of an integration membrane protein STY in preparing a reagent for promoting the adhesion of cells. The invention also discloses a method for changing the adhesion property of the cells by utilizing the integration membrane protein STY. The invention also discloses a specific antibody of the integration membrane protein STY.
Owner:SHANGHAI SIXTH PEOPLES HOSPITAL

Mesoporous molecular sieve compound laser direct structuring material and application thereof

The invention discloses a mesoporous molecular sieve compound laser direct structuring material. The mesoporous molecular sieve compound laser direct structuring material is prepared from, by weight, 70-95% of polycarbonate, 1-10% of a laser direct structuring additive, 1-5% of a phosphate ester / mesoporous molecular sieve hybrid material, 1-15% of a flexibilizer and 0.5-5% of other additives. The phosphate ester / mesoporous molecular sieve hybrid material is prepared from phosphate ester and a mesoporous molecular sieve. The invention further discloses the phosphate ester / mesoporous molecular sieve hybrid material and a preparation method thereof. The mesoporous molecular sieve compound laser direct structuring material, the phosphate ester / mesoporous molecular sieve hybrid material and the preparation method thereof have the advantages that the phosphate ester / mesoporous molecular sieve hybrid material can promote the carbon formation action during laser activation, and is conductive to shortening the plating time; the special structure of the mesoporous molecular sieve is conductive to the adhesion of metal to the surface of a base material, and can significantly improve the bonding strength between a cladding layer and the base material.
Owner:无锡赢同新材料科技有限公司

Silicon-doped hydroxyapatite based vascularization-promoting porous scaffold material, and preparation method and application of porous scaffold material

The invention discloses a silicon-doped hydroxyapatite based vascularization-promoting porous scaffold material, and a preparation method and application of the porous scaffold material, and belongs to the technical field of biological materials. The silicon-doped hydroxyapatite based vascularization-promoting porous scaffold material has a molecular formula of Ca<10>(PO4)<6-x>(SiO4)<x>(OH)<2-x>,wherein x is more than 0 and less than 0.75. The stent material provided by the invention has directional gradient pores which are in communication along the radial direction, and meanwhile, the porescommunicate with each other, so that cell adhesion and regeneration are facilitated, and whole-layer skin repair related cells grow into the center from the edge and the bottom of a wound. In addition, the scaffold material prepared by the preparation method also has good biocompatibility, controllable biodegradability and mechanical property, and has a wide application prospect.
Owner:WUHAN UNIV OF TECH

Power battery and battery cloud platform management method

The invention discloses a power battery. The power battery comprises a battery shell, an electrode group and an electrolyte, wherein the electrode group is coated in the battery shell; the electrode group is formed by superposing a plurality of positive plates, negative plates and diaphragms; the positive plate is coated with a high-nickel positive electrode material composition, the negative plate is coated with a silicon-based negative electrode material composition, and the high-nickel positive electrode material is adopted to be matched with the silicon-based negative electrode material, so that the energy density of the single battery reaches 281Wh / kg, and the capacity is kept at 80% after the single battery is charged and discharged at the rate of 1C for 350 times at the room temperature; a lithium-rich positive electrode material is adopted to be matched with the silicon-based negative electrode material, so that the energy density of a single battery reaches 302Wh / kg, and the capacity is kept at 80% after the single battery is charged and discharged at the rate of 0.5C for 195 times at the room temperature circulation. Meanwhile, the invention further provides a battery cloud platform management method, model parameter changes of a polarization link are considered, battery safety design is guided through model research, battery manufacturing process parameters are controlled through a digital intelligent manufacturing technology, and the battery manufacturing consistency is guaranteed.
Owner:CHONGQING ACADEMY OF SCI & TECH

Application of lactobacillus acidophilus S-layer protein to intestinal cell adhesion and macrophage proliferation

The invention relates to an application of lactobacillus acidophilus S-layer protein in intestinal cell adhesion and macrophage proliferation. An extraction method of the lactobacillus acidophilus S-layer protein comprises the following steps of destroying hydrogen bonds on the surface of lactobacillus acidophilus cell walls by using neutral 4-5mol / L lithium chloride, and purifying by gel filtration or ion exchange chromatography, to obtain the lactobacillus acidophilus S-layer protein. The lactobacillus acidophilus S-layer protein is beneficial to adhesion of lactobacillus acidophilus to intestinal cells, the adhesion function of lactobacillus acidophilus to intestinal cells is reduced along with extraction and separation of the S-layer protein, and the lactobacillus acidophilus S-layer protein is also beneficial to macrophage proliferation and macrophage lysosome secretion within a proper concentration range, and cell autoimmunity enhancement is realized.
Owner:INNER MONGOLIA PUZE BIOLOGICAL PROD CO LTD

Adhesive tape specially used for three-dimensional (3D) printing

The invention discloses an adhesive tape specially used for three-dimensional (3D) printing. The adhesive tape consists of an adhesive A coating layer, a base material, an adhesive B coating layer and release paper, wherein the two surfaces of the base material are firstly and respectively coated with adhesive A and adhesive B; the thickness of the adhesive A coating layer is 0.075-0.25mm, and the thickness of the adhesive B coating layer is 0.05-0.20mm; the release paper covers one side of the adhesive A coating layer. The adhesive tape provided by the invention has high temperature resistance; after the adhesive tape is stuck on a 3D printer platform and the printer platform is heated, a print product is firmly stuck on the printer platform, so that the phenomena of warping and even stripping can be avoided. When the printer platform is cooled, the adhesion degree of an upper surface bonding layer is reduced, so that the product can easily get away from the platform. After the adhesive tape is used, no adhesive residue exists on the surface of the product; furthermore, the adhesive tape can be repeatedly used for a plurality of times.
Owner:FUJIAN NORMAL UNIV

Preparation method of electronic circuit board cleaning agent

The invention provides a preparation method of an electronic circuit board cleaning agent. The preparation method comprises the following steps: firstly, mixing ethylene glycol monomethyl ether, 1-hydroxy-ethanesulfonic acid and a polyol solvent to obtain a premixed solution; dissolving polyethylene glycol oleate, sodium diethylhexyl sulfosuccinate, secondary alkyl sodium sulfonate, alkyl polyglucoside and potassium pyrophosphate into deionized water, adding the premixed solution, N-methyl-2-pyrrolidone, modified silica gel and 2, 2 '-azodiisobutylamidine dihydrochloride, and carrying out reflux reaction in a nitrogen atmosphere so as to obtain the product. The cleaning agent is suitable for cleaning electronic circuit boards and has a good cleaning effect and does not cause corrosion andrusting of the electronic circuit boards.
Owner:长沙凯泽工程设计有限公司

A Rapid Preparation Method of Dry Silver Stained Samples of Freshwater Ciliates

The invention discloses a rapid preparation method for dry silver-stained samples of freshwater ciliates, belonging to the field of biotechnology. The method of the present invention comprises: (1) picking and collecting ciliates, and cleaning the surface of the ciliates; (2) adhering the clean worm liquid obtained from cleaning to the surface of a clean glass slide treated with polylysine, and removing the ciliate liquid Divide into several small drops and blow dry; (3) Add silver nitrate solution dropwise to the surface of the worm body, and clean the residue after standing; (4) Use a halogen cold light source to irradiate and develop; (5) Rinse the scum and dry it; (6) Add neutral gum dropwise to the surface of the worm body, add a cover slip and seal the slide. The method of the invention can efficiently and high-quality prepare dry silver-stained samples of freshwater ciliates, and at the same time greatly simplifies the film-making steps, and the invention does not need to use a developing solution, thereby saving raw material costs. In addition, the sample of the present invention is irradiated and developed under a cold halogen light source after being stained with silver nitrate, which is not affected by weather factors and is easier to control.
Owner:INST OF AQUATIC LIFE ACAD SINICA

Drug coating solution used for drug-coated balloon and drug-coated balloon

The invention provides a drug coating solution used for a drug-coated balloon and the drug-coated balloon, and belongs to the technical field of pharmacy. The drug coating solution provided by the invention takes pectin as an excipient of the drug-coated balloon, and is conducive to adhesion of the drug coating solution and an empty balloon after being mixed with an active drug (paclitaxel or docetaxel). When the drug-coated balloon reaches a damaged site, the pectin is conducive to quick release of the active drug from the coating surface of the balloon, and the active drug deposits on the surface of a blood vessel wall to reach effective drug concentration. An arginine-glycine-aspartic acid (RGD) peptide is a structural recognition motif of cell surface integrin, including alpha-nu-beta3 and alpha-5-beta-1, and is associated with the process of anchoring an extracellular matrix. RGDS-OCH2(CH2)6CH3 is added into the drug coating solution provided by the invention, can be used as integrin on targeting vascular endothelial cells, enhances absorption of the active drug, and meanwhile, reduces the loss of the active drug during delivery.
Owner:CAPITAL UNIVERSITY OF MEDICAL SCIENCES

Silicon-doped medical pure titanium surface porous bioactive coating and preparation method thereof

The invention provides a silicon-doped medical pure titanium surface porous bioactive coating and a preparation method thereof, and belongs to the technical field of biomedical materials. According tothe bioactive coating and the preparation method, composite system solutions with sodium silicate, sodium polyphosphate and calcium acetate are used as electrolytes, and micro-arc oxidation treatmentis carried out by taking a titanium base material as a positive electrode and by taking a stainless steel working groove as a negative electrode; and the temperature of the electrolyte is kept between 10-30 DEG C, and the current density is 8-30 A / dm2, the oxidation time is 2-20 minutes, the frequency ranges from 200 Hz to 1200 Hz, and the duty ratio is 5-40%. According to the bioactive coating and the preparation method, the porous bioactive coating is good in hydrophilicity and high in surface energy, and contains silicon, calcium and phosphorus; and in order to solve the problems that thetraditional medical pure-titanium mechanical strength is low, the biological activity is insufficient, and the requirement of the clinical application is difficult to meet, and the simple, rapid and low-energy efficient preparation method is provided and has a wide application prospect in the fields of biomedical materials and the like.
Owner:JIANGSU UNIV

Biomedical pure magnesium surface functional structured ion implantation modified layer and preparation method and application thereof

The invention discloses a biomedical pure magnesium surface functional structured ion implantation modified layer. The modified layer comprises a manganese modified layer which is subjected to ion implantation and is uniformly distributed on the pure magnesium surface. The manganese modified layer comprises a manganese simple substance positioned on the inner layer and manganese oxide positioned on the surface layer, wherein the content of the manganese oxide is gradually increased from inside to outside. The invention further discloses a preparation method of the biomedical pure magnesium surface functional structured ion implantation modified layer. The invention also discloses application of the biomedical pure magnesium surface functional structured ion implantation modified layer in degradable bone implant materials. According to the method, uniform galvanic corrosion can be formed at the initial soaking stage of pure magnesium in simulated body fluid, deposition of calcium-phosphorus compounds similar to human bone components is promoted, corrosion is converted into uniform corrosion along with time extension, controllable degradation is achieved, on the basis that the corrosion resistance of biomedical magnesium is effectively improved, the biocompatibility is further improved, and the application range is expanded.
Owner:NANJING INST OF TECH

Bionic in-situ regeneration repair nano sticking patch and preparation method and application thereof

The invention relates to a bionic in-situ regeneration repair nano sticking patch, which is formed by overlapping an layer A with a cationic group material and a layer B with an anionic group material sequentially, wherein the sticking patch comprises 20 to 80 percent by mass of the A layer with the cationic group material and the balance of the layer B with the anionic group material; layer A with the cationic group material comprises at least one of polysaccharide with a cationic group, protein with the cationic group or opypeptide (polypeptide) with the cationic group; layer B with the anionic group material comprises at least one of polysaccharide with an anionic group, protein with the anionic group or opypeptide (polypeptide) with the anionic group; and the sticking patch comprises not more than 10 percent by mass of added functional factors and / or functional polypeptide. The raw materials used by the invention are materials which can be degraded in vitro and have biocompatibility. The sticking patch is flexible, has good tissue adhesivity, is suitable for concave-convex surfaces of visceral organs, has strong stretching resistance and air pressure resistance, is suitable for application of sticking, sealing, leak stoppage, hemostasia, isolation, repair, adhesion prevention and artificial meninges of defect tissues and can also be used as a slowly-releasing carrier of a medicament and a nano-grade tissue engineering support material.
Owner:SUZHOU BOCHUANG TONGKANG PHARM TECH CO LTD

Application of sodium hypochlorite in preparing single-layer double-sided polypropylene/polydopamine patch

The invention discloses application of sodium hypochlorite in preparing a single-layer double-sided polypropylene / polydopamine patch. According to the application disclosed by the invention, by usingthe principles that sodium hypochlorite can quickly peel a polydopamine film from polypropylene and the polypropylene patch density is smaller than that of a saturated saline solution, a single-layerpatch is divided into two sides on nanoscale, one side is a polypropylene / polydopamine film face which can effectively prevent the patch from being attached to organs in the enterocoelia, and the other side is a polypropylene face which is exposed after the polydopamine nanofilm is peeled; the polypropylene face is internally in contact with peritoneum to improve abdominal wall tension, so that displacement risk is reduced, the structure of the patch is more reasonable, and requirements in the peritoneum and the enterocoelia are met simultaneously. Meanwhile, the preparation method is not related to stacked composition of varieties of composite materials, the thickness of the obtained patch is macroscopically kept as the thickness of a pure PP patch, and the patch is lighter and thinner and has a great clinical application value.
Owner:SUN YAT SEN UNIV

Novel interior decorating material for automobile and modification method thereof

The invention provides a novel interior decorating material for an automobile and a modification method thereof. The interior decorating material for the automobile comprises an epidermal layer, a foaming layer, a hot melt adhesive layer and a skeleton material which are sequentially stacked. The modification method comprises the following steps: (1) coating a surface of the skeleton material witha modifier, and forming a modified coating after curing, wherein the modifier comprises organic sulfonate, hydroxied acrylate and maleic anhydride grafted polypropylene; (2) subjecting the skeleton material coated with the modified coating to surface treatment with a supersonic flame to obtain a modified skeleton material; (3) subjecting the modified skeleton material to hydrothermal treatment; (4) thermally adhering the epidermal layer, the foaming layer and the hot melt adhesive layer simultaneously, and then compounding the layers after the thermal lamination with the modified skeleton material after the hydrothermal treatment together by vacuum forming. With the adoption of the modification method provided by the invention, the surface tension of the skeleton material of the interiordecorating material for the automobile is improved, the binding fastness between the skeleton material and the foaming layer is enhanced, and the impact resistance of the interior decorating materialfor the automobile is improved.
Owner:DONGGUAN XIONGLIN NEW MATERIAL TECH

Composite hydrogel based on zwitterions and keratin and preparation method thereof

The invention discloses composite hydrogel based on zwitterions and keratin and a preparation method thereof. The composite hydrogel is prepared from the following raw material components by weight: 400-600 parts of a zwitterion monomer, 0-60 parts of keratin, 6-30 parts of a cross-linking agent and 0-10 parts of an initiator, and the invention also provides a preparation method of the composite hydrogel. The composite hydrogel based on the zwitterions and keratin has excellent biocompatibility and an anti-adhesion effect; the synthetic method is simple and excellent degradability is achieved;keratin with good biocompatibility and a zwitterionic compound monomer with protein adsorption resistance are adopted as the raw materials, and the zwitterionic degradable hydrogel is prepared through a free radical polymerization reaction and serves as an anti-adhesion material to prevent postoperative adhesion. The composite hydrogel can be used as an anti-adhesion wound dressing in the field of biomedicine.
Owner:NANJING NORMAL UNIVERSITY

A biomedical pure magnesium surface functional structured ion implantation modified layer and its preparation method and application

The invention discloses a functional structured ion implantation modified layer on the surface of biomedical pure magnesium, which comprises a manganese modified layer ion-implanted and evenly distributed on the surface of the pure magnesium, and the manganese modified layer includes manganese in the inner layer Elemental substance and manganese oxide located on the surface with increasing content from inside to outside. The invention also discloses a preparation method of the biomedical pure magnesium surface functional structured ion implantation modification layer. The invention also discloses the application of a biomedical pure magnesium surface functional structured ion implantation modified layer in a degradable bone implant material. The invention enables pure magnesium to form uniform galvanic corrosion at the initial stage of immersion in simulated body fluid, and promotes the deposition of calcium-phosphorus compounds similar to human bone components. As time goes on, the corrosion type changes to uniform corrosion, achieving controllable degradation. On the basis of effectively improving the corrosion resistance of biomedical magnesium, the biocompatibility is further improved and the application range is expanded.
Owner:NANJING INST OF TECH

Engine crankcase oil and gas pre-filter

The invention discloses an engine crankcase oil-gas pre-filter, which is installed above the oil-collecting chamber of a cylinder head cover, and comprises a pre-filter cover, a pre-filter bottom plate and a labyrinth assembly, and the labyrinth assembly is installed on the pre-filter cover and the pre-filter bottom plate In the enclosed space; the labyrinth component is a frustum-shaped cavity structure, and there is an annular constriction channel in the cavity, and a labyrinth swirl cavity is located on the rear side of the annular constriction channel; the pre-filter oil and gas inlet is set on the pre-filter bottom plate, and the pre-filter oil and gas The inlet is communicated with the air port on the cylinder head cover, and the oil and gas outlet is arranged on the pre-filter cover; the oil-passing hole is set on the bottom plate of the pre-filter. The oil-gas pre-filter of the present invention has a more compact pre-filter structure, smoother oil return and better oil-gas pre-separation effect.
Owner:GUANGXI YUCHAI MASCH CO LTD
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