83results about How to "Promote repair and regeneration" patented technology

An articular cartilage fixation device and method for repairing and regenerating diseased or injured soft tissue such as articular cartilage of the knee, hip, shoulder, and the like. A cartilage flap or cartilage repair device is retained within the chondral or osteochondral defect for a sufficient amount of time such that the cartilage repair device can perform its function and facilitate an appropriate healing response. A plurality of biocompatible anchors are attached to a plurality of flexible members and are shaped to seat into the tissue beneath or near the defect such that the cartilage flap is retained within the defect.

The invention relates to the technical field of cosmetics, and discloses a nourishing and anti-aging essence and a nourishing and anti-aging cosmetic mainly containing Chinese herbal medicines. The nourishing and anti-aging essence consists of active components and a base component, wherein the active components include a dendrobium officinale extract, superoxide dismutase, squalane and a liquorice extract. The nourishing and anti-aging essence and the nourishing and anti-aging cosmetic disclosed by the invention are non-irritant to skin, and are capable of effectively retaining skin moisture, promoting repair and regeneration, delaying skin aging and recovering skin elasticity.

The invention discloses a medicine for treating oculopathy. The medicine comprises the following active pharmaceutical ingredients in parts by weight: 12-17 parts of cassia seed, 12-17 parts of stem of noble dendrobium, 10-15 parts of climbing groundsel herb, 8-13 parts of chrysanthemum, 8-13 parts of feather cockscomb seed and 1-3 parts of borneol. The medicine is obtained by weighing the active pharmaceutical ingredients according to the parts by weight, washing, drying and sterilizing, soaking and decocting the active pharmaceutical ingredients, filtering the decoction, cooling the filtrate and re-sterilizing the filtrate. The medicine provided by the invention has the characteristics of quickness in effect taking, good curative effects and no toxic or side effects. The medicine is clinically used by totally 836 patients and the average cure rate is 91.5%. The medicine is convenient and fast to use.

The invention belongs to the fields of diabetes mellitus and medicinal chemistry, and relates to the application of icariin or icarisid II in preparation of a medicine for preventing and curing diabetic retinopathy, in particular to the application of the icariin, an icariin-containing extract, the icarisid II or an icarisid II-containing extract in preparation of a medicine for preventing and / or curing the diabetic retinopathy. The icariin, the icariin-containing extract, the icarisid II or the icarisid II-containing extract have effective effects on repair or prevention and cure of the diabetic retinopathy, can improve the retinal vessel endothelial cell function remarkably, and can promote the reparative regeneration of optic nerve cells for diabetes mellitus.

The present invention relates to the field of hematopoietic stem cells. More specifically, the present invention provides methods and composition useful for peripheral blood stem cell mobilization. In one embodiment, a method of treating an organ transplant recipient comprises administering to the recipient a low dose of Tacrolimus in an amount sufficient to mobilize stem cells to the peripheral blood of the recipient. In a specific embodiment, the low dose of Tacrolimus is in the range of about 0.05 mg / kg to about 0.5 mg / kg.

The invention discloses a burn and scald pain relieving emollient ointment aiming to provide an external pure Chinese medicinal herb ointment preparation capable of curing diseases including serious burn and scald. The burn and scald pain relieving emollient ointment is prepared by 15 Chinese medicinal herbs including pangolin, radix angelica sinensis, and the like, wherein the Chinese medicinal herbs are natural medicinal materials with natural flavors such as a warm flavor, a cool flavor, a bitter flavor, a pungent flavor, a sweet flavor and a cold flavor, prepared through technological measures, i.e. concoction, compatibility, preparation processing, and the like to lead to harmonious natural flavors and stable and prominent efficacy, and mixed to form an ointment preparation with functions of purging intense heat and detoxicating, removing damp-heat, cooling blood and eliminating stasis, promoting blood circulation and stopping pain, dissolving purpura and detoxicating and efficacies of moisturizing, moisture protection and constriction. The medicine is sufficiently blended with a wound surface in the curing process so as to ensure the medicine to seal the wound surface to enable the wound surface not to be exposed in air, thereby the wound surface is not infected by external toxins so as to be beneficial to the repair and the regeneration of wound surface tissues.

The present invention provides a recombinant human type XVII collagen, which consists of or comprises the amino acid sequence shown in (A)n, wherein A is shown in SEQ ID NO.2 Sequence or a sequence after amino acid modification to a certain extent on the basis of SEQ ID NO.2 or a sequence with greater than 80% homology with SEQ ID NO.2; wherein n is an integer greater than or equal to 1; wherein each A The same or different and repeat in tandem with A as the basic unit, and each of the same or different A is directly connected by a peptide bond. In the present invention, it is verified that the collagen can not only realize the high-efficiency secretion and soluble expression of human type XVII collagen in eukaryotic host cells such as Pichia pastoris, but also has better cell adhesion than commercial natural human collagen activity, promoting cell migration, excellent tissue regeneration and biological activity promoting hair follicle repair and regeneration, and can be produced industrially.

The invention discloses a fully-degradable heart occluder coating capable of promoting cardiac muscle tissue repair and a preparation method of the fully-degradable heart occluder coating. The preparation method comprises the following steps: (1) cleaning a substrate material; (2) pretreating a substrate material polyphenol; (3) aminating the surface of the substrate material; and (4) introducing the activated recombinant collagen to the surface of the substrate material. The extracellular matrix bionic coating based on the recombinant collagen is constructed by activating a substrate material through a polyphenol compound, introducing a polyamino compound and further effectively loading a recombinant collagen component on the surface of the material through an amino amplification effect. Growth of endothelial cells and cardiac muscle cells at a defective part is realized, and inflammatory response is reduced, so that the purpose of effectively promoting regeneration and repair of defective cardiac muscle tissues is achieved.

The invention discloses a wound dressing. The wound dressing comprises hydroxyethyl starch with the molecular weight of 100,000-700,000 Da. The wound dressing is prepared from, in parts by weight, 20-80 parts of sodium alginate, 20-80 parts of hydroxyethyl starch and 0-5 parts of calcium chloride. The wound dressing can rapidly absorb water, blood, effusion and other liquids on the surface of a wound to form a gel protection layer and stays on the wound for 7 d or longer; influence of wound bleeding on an operation can be reduced, cleanness of the operation view field is kept, and the operation can be performed smoothly; the wound dressing can pack tissue to prevent contact of helicobacter pylori and other pathogenic microorganisms with the wound and prevent infection, and application ofantibiotics is reduced; the wound dressing can be applied to the wound of a gastrointestinal mucous membrane, effectively resist attack and erosion of gastric acid, pepsin and other attack factors tothe wound; the wound dressing can effectively stimulate the gastrointestinal tract to promote increase of activities of the gastrointestinal tract and recover the movement function of the gastrointestinal tract.

The invention relates to the technical field of cosmetics and discloses a moisturizing and brightening cream mainly composed of Aesculus chinensis extract and Centella asiatica extract. The active ingredient comprises Aesculus chinensis extract, Centella asiatica extract, collagen, glycerol and hydrolyzed sodium hyaluronate. The brightening cream has no irritation to skin, can effectively maintainskin moisture, promote repair and regeneration, delay skin aging, and restore skin elasticity.