The present invention relates to a dietary therapy liquid, specifically to an enzyme dietary therapy liquid for removing toxins in a human body, and a preparation method thereof. The enzyme dietary therapy liquid is prepared by carrying out closed fermentation on orange, pomelo, lemon, apple, vatica astrotricha, Noni fruit, pineapple, carrot, cucumber, wax gourd, bitter gourd, asparagus, purple cabbage, celery, tomato, turnip, burdock, sweet potato, kelp, black fungus, red bean, green tea, assam tea leaf, hemp fruit, garden radish seed, cape jasmine, corn stigma, medlar, obtuseleaf senna seed, aloe, licorice root, common yam rhizome, red date, hawthorn, olive, camellia fruit, honey, black sugar, rice vinegar and apple vinegar, is rich in amino acids, vitamins, trace elements, polypeptides, polysaccharides, flavones, anthocyanins, enzymes, SOD and other nutrients, has five comprehensive detoxication characteristics such as heat clearing detoxication, blood stasis removing detoxication, dampness removing detoxication, blood toxin clearing detoxication, and body resistance supporting detoxication, and provides good dietary therapy effects for various pathological changes and diseases caused by toxins accumulated in various organs.