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278 results about "Biomineralization" patented technology
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Biomineralization is the process by which living organisms produce minerals, often to harden or stiffen existing tissues. Such tissues are called mineralized tissues. It is an extremely widespread phenomenon; all six taxonomic kingdoms contain members that are able to form minerals, and over 60 different minerals have been identified in organisms. Examples include silicates in algae and diatoms, carbonates in invertebrates, and calcium phosphates and carbonates in vertebrates. These minerals often form structural features such as sea shells and the bone in mammals and birds. Organisms have been producing mineralised skeletons for the past 550 million years. Ca carbonates and Ca phosphates are usually crystalline, but silica organisms (sponges, diatoms...) are always non crystalline minerals. Other examples include copper, iron and gold deposits involving bacteria. Biologically-formed minerals often have special uses such as magnetic sensors in magnetotactic bacteria (Fe₃O₄), gravity sensing devices (CaCO₃, CaSO₄, BaSO₄) and iron storage and mobilization (Fe₂O₃•H₂O in the protein ferritin).
Apparatus and method for detecting and identifying infectious agents
Solid phase methods for the identification of an analyte in a biological medium, such as a body fluid, using bioluminescence are provided. A chip designed for performing the method and detecting the bioluminescence is also provided. Methods employing biomineralization for depositing silicon on a matrix support are also provided. A synthetic synapse is also provided.
Owner:PROLUME
Crack self-remediation regenerated concrete based on urease production microorganism mineralization deposition and preparation method
ActiveCN106699026AStrong adaptability to high alkaline environmentAdaptableOn/in inorganic carrierWater reducerMechanical property
The invention discloses crack self-remediation regenerated concrete based on urease production microorganism mineralization deposition and a preparation method. The crack self-remediation regenerated concrete comprises components, namely, expanded perlite carried with urease production microorganisms, cement, stone, sand, silica fume, water, urea, calcium chloride, a urease production microorganism suspension and a water reducing agent. The urease production microorganisms are adopted as a concrete crack remediation agent, urease can be generated through metabolism through the urease production microorganisms, and the urea can be decomposed into NH4<+> and CO3<2+>, and furthermore the calcium carbonate can be mineralized and deposited to remedy cracks. In the preparation process, a part of the crack remediation agent is directly mixed with the concrete, then cracks and holes in regenerated crude aggregate self and weak adhesion areas between regenerated aggregate and a new cement stone base can be remedied, and thus the mechanical property of the regenerated concrete can be improved; meanwhile, the other part of the crack remediation agent is firstly adsorbed into an expanded perlite carrier and is further mixed into the concrete, then the crack self-remediation property of the regenerated concrete in the service period can be improved, and thus the anti-penetrability performance and the durability of the regenerated concrete can be improved.
Owner:TAIYUAN UNIV OF TECH
Method for restoring mine entironment
InactiveCN101037268ALow costLow infrastructure costWaste water treatment from quariesWater contaminantsEcological environmentSulfate-reducing bacteria
A method of repairing mine ecological environment comprises the treatment of mine environment contamination, wherein the tailings, the barren rock, the smelting slag, the waste water from ore cleaning, the waste water from smelting, the acid mine drainage and the ore yard leachwater which are generated from mine development are collected into the tailings storage, at the same time, sludge and organic matter capable of being degradated by microbiology are added therein, and then the tailings storage is given an anaerobic environment artificially, so that, under the action of microbiology and sulfate reducing bacteria, sulfur ion is generated and the pH value of the tailings storage is increased, a plurality of heavy metal ions are cured and settled by sulfur ion to avoid migration, a biomembrane layer-sulfate reducing bacteria reducing-induction biomineralization precipitation composite geochemical barrier is generated in the tailings storage. The repairing of mine ecological environment is realized by the treatment of mine environment contamination. The present invention can be used for tailings storage pollution prevention in tour, and can be used for closing the repairing of mine ecological environment, or can be used for designing new tailings storage by using the technology of the present invention.
Owner:ELION ECOLOGICAL RESTORATION
Apparatus and method for detecting and identifying infectious agents
Solid phase methods for the identification of an analyte in a biological medium, such as a body fluid, using bioluminescence are provided. A chip designed for performing the method and detecting the bioluminescence is also provided. Methods employing biomineralization for depositing silicon on a matrix support are also provided. A synthetic synapse is also provided.
Owner:PROLUME
Nano layered calcium carbonate base bionic composite material and synthetic method thereof
InactiveCN101085880ACalcium/strontium/barium carbonatesPigment treatment with non-polymer organic compoundsEnvironmental geologyInorganic chemistry
The invention relates to calcium carbonate based artificial material and the synthesizing method. It is characterized in that the method comprises following steps: adding low- molecular weight organic matter into system of calcium chloride and sodium carbonate according to a certain proportion, heating, organic molecule absorning selectively on crystal surface to nanocrystal growth along said crystal surface, so it is thin structure for crystal, assembling the crystal thin structure on three-dimensional orientation under interactive action of organic molecule and extension growth of crystal, getting staged layer structure crystal, and that is mentioned final product. The invention is of great importance for understanding biomineralization process and atificial synthesis for biological mineralising material.
Owner:SHANGHAI INST OF CERAMIC CHEM & TECH CHINESE ACAD OF SCI
Method of inducing biomineralization method of inducing bone regeneration and methods related thereof
A method of inducing biomineralization in a tissue, which method comprises administering to the tissue a source of Phosphophoryn (PP) in an amount sufficient to induce biomineralization; a method of treating tooth sensitivity or injured pulp tissue; a method of inducing differentiation of a cell into an osteogenic cell or odontogenic cell; a method of inducing bone or dentin regeneration; a method of inducing periodontal regeneration; a method of inducing differentiation of a cell into a cementoblast, osteoblast, or periodontal ligament cell; and a composition comprising a source of PP and a carrier.
Owner:UNIVERSITY OF PITTSBURGH
Injectable-porous-drug loaded polymethyl methacrylate-based composite scaffold bone transplant material and preparation method thereof
ActiveCN104906637AEasy to prepareGood biocompatibilityProsthesisReaction temperaturePolymethyl methacrylate
The present invention discloses an injectable-porous-drug loaded polymethyl methacrylate-based composite scaffold bone transplant material and a preparation method thereof, and belongs to the field of organic functional materials preparation. The polymethyl methacrylate-based composite scaffold bone transplant material uses polymethyl methacrylate (PMMA) as a scaffold for providing mechanical supporting, and a chitosan-based thermosensitive hydrogel as a pore forming agent and an osteoconductive material and a drug carrier, and the polymethyl methacrylate (PMMA) and the chitosan-based thermosensitive hydrogel are mixed with each other to form an injectable-porous three-dimensional structural bone cement composite. The scaffold bone transplant material is simple in preparation method, suitable in reaction temperature, and good in biocompatibility, has matched mechanical properties, good biological mineralization and corresponding anti-bacterial, anti-inflammatory or anti-tumor capabilities, and has broad prospects in clinical application of reconstruction of bone tissues in future.
Owner:WUHAN UNIV
Polydopamine-modified halloysite nanotube / polylactic acid composite material and preparation and application thereof
ActiveCN105566872ASolving Dispersion ProblemsSolve interface compatibility issuesMonocomponent polyesters artificial filamentArtifical filament manufactureHydroxyapatite crystalNanotube
The present invention discloses a polydopamine-modified halloysite nanotube / polylactic acid composite material and preparation and application thereof. The polydopamine-modified halloysite nanotube / polylactic acid composite material comprises 0.05 to 60% by mass of polydopamine-modified halloysite nanotubes and 40 to 99.95% by mass of polylactic acid. By surface modification of the halloysite nanotubes, dispersion of the halloysite nanotubes in a polylactic acid matrix and interface compatibility of the halloysite nanotubes and the polylactic acid matrix can be solved, and the polylactic acid matrix can be effectively enhanced by the halloysite nanotubes; excellent cell affinity and osteogenic activity can be given to the polydopamine-modified halloysite nanotube / polylactic acid composite material, and more significantly, by the use of biological mineralization of a polydopamine layer on the surface of the halloysite nanotubes for formation of hydroxyapatite crystals, eventually good osteo inductivity can be given to the polydopamine-modified halloysite nanotube / polylactic acid composite material. The polydopamine-modified halloysite nanotube / polylactic acid composite material is simple in preparation method, mild in reaction conditions, low in price, and suitable for industrial production.
Owner:JINAN UNIVERSITY
Method for prenaring spherical hydroxy-apatite nano crystal
The process of preparing spherical nanometer hydroxyapatite crystal in water solution features that spherical nanometer hydroxyapatite crystal is synthesized with water soluble polymer PVP as template and through a biomineralization process. The process includes: spreading Ca(NO3)2íñ4H2O powder in the bottom of container A, preading (NH4)3PO4íñ3H2O powder in the weight ratio to Ca(NO3)2íñ4H2O of 1 to 1.67 in the bottom of container B, setting the container B inside the container B, slowly adding PVP aqua of pH 10.5 and concentration 0.02-2 wt% along in inner walls of the two containers to Ca(NO3)2íñ4H2O concentration of 0.01-0.20 mol / L and (NH4)3PO4íñ3H2O concentration of 0.006-0.12 mol / L and the solution overflow through the edge of the container B, stilling at 25 deg.c for 7 days to obtain precipitate, washing the precipitate, sucking filtering and drying to obtain the spherical nanometer hydroxyapatite crystal product. Altering the PVP concentration can regulate the crystal size in 15-150 nm.
Owner:FUJIAN NORMAL UNIV
Hydroxyapatite/chitosan composite coating and preparation method thereof
InactiveCN103272269AImprove mechanical propertiesImprove biological activityCoatingsProsthesisChitosan coatingPhosphate ion
The invention discloses a hydroxyapatite / chitosan composite coating and a preparation method thereof. The preparation process mainly comprises the following steps of: (1) preparing liquor containing chitosan, calcium ions and phosphate anions; (2) based on biomedical metal as a matrix, preparing a chitosan coating containing calcium ions and phosphate anions by a dipping-pulling method; and (3) converting the chitosan coating containing calcium ions and phosphate anions to the hydroxyapatite / chitosan composite coating by a biomineralization method. The coating prepared by the invention adequately combines advantages of the biomedical metal matrix, hydroxyapatite and chitosan. With the biomedical metal matrix, the coating has stronger mechanical property. With a porous structured formed by sequentially arranging sheet hydroxyapatite, the coating has good biocompatibility. Chitosan organic matters are introduced, so that not only is the binding capacity of hydroxyapatite and the metal matrix remarkably improved, but also the coating material is endowed with the antibacterial performance.
Owner:SHANGHAI NORMAL UNIVERSITY
Method for preparing Fe2O3 nanometer particles by using collagen as biological mineralization template
The invention discloses a method for preparing Fe2O3 nanometer particles by using collagen as a biological mineralization template. The method comprises the following steps of (1) preparing recombinant collagen through a biological genetic engineering technique: (a) determining the sequence of the recombinant collagen; (b) synthesizing nucleic acid for coding the recombinant collagen; and (c) preparing and purifying the recombinant collagen; and (2) preparing an alpha-Fe2O3 nanometer material: (a) compounding a uniform mixed solution of the recombinant collagen and ferric trichloride hexahydrate; (b) preparing nanoscale alpha-Fe2O3 through a hydrothermal reaction kettle; and (c) performing purification on the prepared nanometer material, and then performing drying preservation on the purified nanometer material. According to the method disclosed by the invention, the recombinant collagen is used as the biological template, the ferric trichloride hexahydrate is used as a raw material, and by a hydrothermal method, the alpha-Fe2O3 nanometer material of which the magnitude and the topology are controllable is prepared. In the whole synthetic process of the method disclosed by the invention, any other chemical reagents do not need to be added, or post-treatment is not needed, the method is simple and convenient and easy to operate and has great application prospects, and a basis can be provided for the large-scale production of the alpha-Fe2O3 nanometer material.
Owner:兰州生物技术开发有限公司
Natural polypeptides material for biomineralization and preparation method thereof
InactiveCN101628126AGood biocompatibilityImprove biological activityOn/in organic carrierMacromolecular non-active ingredientsHydroxylapatiteBiocompatibility Testing
The invention relates to natural polypeptides material for biomineralization and a preparation method thereof, in particular to a natural polypeptides material for preparing a crystal structure with fine biocompatibility by mineralization, belonging to the biological medical material field. The polypeptides material containing natural fibroin consists of degumming fibroin of insect silk and spidroin, which can be used for crystals mineralized at room temperature including zinc oxide, ferric oxide, gallium oxide, cobalt oxide, titanium oxide, hydroxylapatite, calcium phosphate and calcium carbonate. The silk fibroin solution after degumming is subjected to water washing, acid hydrolysis, dialysis, centrifuge enrichment to obtain the natural polypeptides material for mineralization, natural polypeptides material can be used for preparing composite materials with fine biocompatibility by mineralization.
Owner:SICHUAN UNIV
Calcium phosphate/collagen/bone-like apatite three-level bionic bone tissue engineering scaffold and preparation method thereof
InactiveCN103341206APromote repair and regenerationGood biocompatibilityProsthesisThree levelApatite
The invention provides a calcium phosphate / collagen / bone-like apatite three-level bionic bone tissue engineering scaffold and a preparation method thereof. The material of the scaffold possesses components similar to natural bone tissues, and an inorganic / organic / inorganic three-level bionic bone-like netted three-dimensional structure. The preparation method comprises: customizing a calcium phosphate ceramic which possesses a bionic porous structure similar to the natural bone micropore structure, filling collagen prepared by simulated body fluid (SBF) into the porous calcium phosphate ceramic base, low-temperature aging to simulate a biomineralization process, in-situ nucleating on the collagen organic macro-molecule matrix, and self-assembly crystallizing to form a third level bone-like apatite layer structure. The composite scaffold material has bionic material components and bionic microstructure both similar to the natural bone tissues, the mechanical properties and the biological activity of the material are substantially improved, and the composite scaffold material has a wide application prospect.
Owner:SICHUAN UNIV
Surface mount method of mineralized collagen gradient coating for medical titanium implant
InactiveCN101984144AEvenly distributedGood biocompatibilityElectrolytic inorganic material coatingBiocompatibility TestingStrong binding
The invention relates to a surface mount method of mineralized collagen gradient coating for medical titanium implant. Based on the effect of voltage and electrolyte composition on in-situ biomineralization self-assembly of collagen in electrolyte, permineralized calcium phosphate layer, mineralized collagen layer and unmineralized pure collagen layer are assembled from the titanium substrate upward in profile by electrochemical codeposition technology. The components and structure of the above product are similar to those of natural bones. The product of good biocompatibility and biological responsiveness can accelerate the osteointegration of implanted area and shorten the period of treatment. The strong binding force between the coating and the titanium substrate prevents the occurrence of coating shedding due to friction stress during the process of implantation. The coating provided by the invention is applicable to clinical applications.
Owner:ZHEJIANG UNIV
Method for preparing different crystal system calcium carbonate by using chitosan
The invention relates to a process for preparing calcium carbonate with different crystal forms by employing chitosan, which belongs to the biomimetic materials field. The steps of the invention comprise adding chitosan in water solution with calcium chloride and urea according to a certain proportion and controlling modality of chitosan molecular chain to hydro-thermally synthesize calcium carbonate with different crystal form via changing pH of reaction solution. The invention realizes the method of synthesizing calcium carbonate with different crystal forms by manual work, and is expected to be applied to the biomineralization process and synthesis of biomineralization materials.
Owner:SHANGHAI INST OF CERAMIC CHEM & TECH CHINESE ACAD OF SCI
Enamel-shaped hydroxyapatite and preparation method and application thereof
ActiveCN101891175AImprove mechanical propertiesUnderstanding the Biomineralization ProcessImpression capsDentistry preparationsApatiteCationic polyelectrolytes
The invention belongs to the technical field of biomedical materials and relates to an enamel-shaped hydroxyapatite and a preparation method and application thereof, in particular to a method for synthesizing the enamel-shaped hydroxyapatite by induction of dual polyelectrolyte. In the method, soluble calcium salt and soluble phosphate are used as raw materials, and the dual polyelectrolyte comprising water-soluble cationic polyelectrolyte and organic polyatomic acid is used as a template; the prepared hydroxyapatite nano rods grow along the specific direction and are mutually stacked closely in parallel to form an enamel-shaped structure; and the diameter of each nano rod is 30-200nm. The method for preparing the hydroxyapatite with the enamel-shaped structure, which is provided by the invention, is not only favorable for people to further understand the biological mineralization processes of enamel crystals but also favorable for improving the mechanical properties of the hydroxyapatite, expands the application of the hydroxyapatite in tooth / bone replacing materials, and provides a new possibility for acquiring and popularizing high-quality medical hydroxyapatite materials.
Owner:江苏先进无机材料研究院
High-performance historic site repair material and preparation method thereof
The invention provides a high-performance historic site repair material and a preparation method thereof. The repair material comprises the following raw materials: 191-287 parts of sticky rice pulp, 115-185 parts of lime, 0-4 parts of brown granulated sugar, 344-398 parts of fine aggregates, 204-268 parts of complex mineral admixture, 11-12 parts of reinforcing agent, and 0-19 parts of mineral pigment. The invention further provides a preparation method of the repair material. The preparation method comprises the following steps: weighing all the raw material according to weight, and forcibly stirring evenly to obtain the repair material. Amylopectin in the sticky rice pulp is a highly branched macromolecule, the setting and hardening processes of the lime and the pozzolanic reaction of the complex mineral admixture are influenced, the strength development of the material is similar to biomineralization process, and a microstructure formed in the process endows the repair material with higher strength and toughness. Furthermore, the material has good compatibility with materials of a historic site body.
Owner:WUHAN UNIV
Method for accelerated dechlorination of matter
InactiveUS7129388B2Accelerated dechlorinationIncreasing rate of biological mineralizationContaminated soil reclamationSolventAnaerobic microorganisms
Accelerated dechlorination of soil and water contaminated with chlorinated solvents is achieved by stimulating anaerobic microorganisms and thus increasing the rate of biological mineralization of the solvents. This is accomplished by a treatment process consisting of colloidal suspension of iron powder, polylactate ester such as glycerol tripolylactate, xylitol pentapolylactate, and sorbitol hexapolylactate, chemical oxygen scavengers in solution with essential nutrients, and vitamin stimulants such as B2 and B12 delivered via compressed gases N or C02 so as not to oxygenate an environment targeted for anaerobic processes. The treatment stimulates naturally occurring microorganisms while oxidizing dissolved phase target compounds via the surface action of the iron particles resulting in the breakdown of chlorinated solvents such as tetrachloroethene, trichloroethene, carbon tetrachloride and their daughter products.
Owner:INNOVATIVE ENVIRONMENTAL TECH
Mineral trioxide aggregate (MTA) composition and use
ActiveUS20120156308A1Good strength developmentFast setting timeHeavy metal active ingredientsBiocideDiseaseHigh fluoride
The present application discloses a fast-setting mineral trioxide aggregate (MTA) with fluoride release for practical treatment of diseases in teeth and bone, e.g. for caries treatment and / or prevention. The cariostatic MTA contain calcia-silica-alumina cement with moderately increased tricalcium aluminate content allowing high calcium hydroxide release. The MTA composition support remineralization and biomineralization, and it is suitable for stimulation of hard tissue regeneration. MTA embodiments contain superplasticizerand nanosilicate for improved mechanical properties. The MTA compositions include optional radiocontrast and nano-enriched leachable fluorine, nitrate, strontium, and phosphate. The fast-setting MTA paste exhibits flow-to-clay-like consistency, which allows new practical applications including cavity lining, temporary restoration, bonding, and cementations in one MTA embodiment. The high calcium hydroxide and high fluoride release are suitable for caries prevention and treatment, and per se inhibition of dental symptoms.
Owner:DENTOSOLVE APS
Method for laminating on surface of cement-based material by using sodium alginate-supported bacterial strain
InactiveCN101759438AImprove impermeabilityPlay a protective effectBacteriaMicroorganism based processesMicroorganismBacterial strain
The invention provides a method for laminating on the surface of a cement-based material by using a sodium alginate-supported bacterial strain. In the method, biomineralization of microorganisms in nature is fully used; a bacterial strain, namely Bacillus pasteurii, having a carbonate mineralization characteristic is selected and used to slowly generate compact and hard calcium carbonate on the surface of the base material in a microenvironment provided by sodium alginate serving as a carrier by using the enzymatic characteristic per se, so that the permeability resistance of the base material is greatly improved, and the base material is protected in situ and strengthened; in addition, the sodium alginate can be gradually decomposed by bacteria with the prolonging of the time so as not to prevent the generated calcium carbonate from tightly combining with the base material; and the sodium alginate serving as the carrier can directly fix the bacterial strain onto the surface of the base material, so that the base material can be protected in situ and strengthened. The method is suitable for practical application, and is a protection method with environmental friendliness, simple process and low cost.
Owner:SOUTHEAST UNIV
Grapheme-based composite film using bacterium as template and preparation method and application thereof
ActiveCN104332322AImprove mechanical propertiesExcellent capacitance performanceHybrid capacitor electrodesHybrid/EDL manufactureCapacitancePorous graphene
The invention relates to a grapheme-based composite film using bacterium as a template and a preparation method and application thereof. The method comprises the following steps: attaching Mn<2+> particles to a cell wall under the static effect by using bacterium as a soft template material in a room temperature agitating condition; uniformly mixing with grapheme; performing vacuum filtration to obtain a self-supporting film; then performing biomineralization to btain high-conductivity porous grapheme / MnOx composite film material. The bacterium template guided grapheme-based composite film is used as a self-supporting electrode material without any adhesive and conductive agent and can be applied to a super capacitor to greatly prolong the cycle service life and improve the capacitance performance of the super capacitor.
Owner:THE NAT CENT FOR NANOSCI & TECH NCNST OF CHINA
Bonding-assisting biological mineralization material and applications thereof in biomimetic mineralization
InactiveCN106473933ASimple preparation processEasy to storeImpression capsDentistry preparationsAdhesiveBiological materials
The invention provides a bonding-assisting biological material and applications of the bonding-assisting biological material in biomimetic mineralization, for promoting the remineralization of type I collagen, demineralized enamel and dentin. The bonding-assisting biological mineralization material is the synthetized amorphous calcium phosphate particles stabilized by non-collagenous protein analogue. According to the applications of the bonding-assisting biological mineralization material in biomimetic mineralization, the assisting mineralization material is mixed with a self-etching adhesive, thus the bonding-assisting biological mineralizer is prepared, the bonding-assisting biological mineralizer coats the surfaces of single-layer recombinant type I collagen, the demineralized enamel and the dentin, and then the mineralization property of the biological mineralizer for the single-layer recombinant type I collagen, the demineralized enamel and the dentin is studied. The existing biological mineralization mode (solutions and paste are adopted, namely, gargling or local coating is adopted) is changed, the assisting mineralization material is mixed with the adhesive, after curing, the liquid state is converted into the solid state, then the adhesive anti-caries coating is formed, and the adhesive anti-caries coating can be adhered to the part needing mineralization for a long term, so that the acting time with teeth is prolonged, the use is simple and convenient, and the self-repairing of the demineralized teeth is promoted.
Owner:ZHEJIANG UNIV
Amphiphilic peptides and hydrogel matrices thereof for bone repair
ActiveUS20100015197A1Accelerate bone repairHigh cure ratePowder deliveryTetrapeptide ingredientsMedicineHydrogel matrix
The present invention relates to the field of tissue engineering and more specifically to amphiphilic peptides and peptide matrices thereof useful in vitro and in situ biomineralization and inducing bone repair. The present invention provides peptides, which are useful in hydrogels and other pharmaceutical compositions, and methods and kits of use for bone repair and promotion of biomineralization. Certain hydrogels according to the invention comprise cells within or adhered to the peptide matrix.
Owner:BONE SCI BIO LTD
Hydroxyapatite toothpaste and preparation method thereof
ActiveCN105640788APromote mineralizationReduce contentCosmetic preparationsToilet preparationsApatiteToothpaste
Owner:HANGZHOU JIAOJIE ORAL HEALTH CARE PRODS
Underwater self-cleaning superoleophobic mineralized fibrous film and preparation method thereof
InactiveCN102758262AOvercome the disadvantage of being easy to wearStable oleophobic propertiesFilament/thread formingNon-woven fabricsFiberComposite film
The invention belongs to the field of self-cleaning organic / inorganic composite films, and particularly relates to an underwater self-cleaning superoleophobic mineralized fibrous film with a non-woven fabric structure and a preparation method of the underwater self-cleaning superoleophobic mineralized fibrous film. The underwater self-cleaning superoleophobic mineralized fibrous film with the non-woven fabric structure is produced by the following steps: a polymer fibrous film with the non-woven fabric structure and containing a mineralizing regulator is obtained by an electrostatic spinning method; the fiber surface of the polymer fibrous film is controllably mineralized by a biomineralization method so as to obtain the organic / inorganic composite underwater self-cleaning superoleophobic mineralized fibrous film with good stability. In air, the invasion of the film surface is hydrophilic; in water, the invasion of the surface is superoleophobic; and in water, the contact angle of the film surface to oil is more than 150 degrees.
Owner:INST OF CHEM CHINESE ACAD OF SCI
Method for preparing biological activity glass nano-fibre cluster
The invention relates to a preparation method of a bioactive glass nanofiber cluster, which is characterized in that A solution which is composed of tetraethyl orthosilicate and triethyl phosphate and B solution which is composed of calcium nitrate tetrahydrate, deionized water, a template agent and a catalyst are firstly prepared, the B solution is slowly dropped into the A solution to form a sol, the sol forms a gel by aging for 4 to 7 days, the gel is dried for 2 to 3 days at the temperature of 80 to 140 DEG C, and finally the nanofiber cluster material is obtained by heat treatment and solidification process at 400 to 700 DEG C and grinding. The weight percentage of the components of the nanofiber cluster is that: 60 to 80 percent of SiO2, 36 to 16 percent of CaO and 4 percent of P2O5. The bioactive glass nanofiber cluster prepared by the invention is composed of nano-fibers that are regularly arranged, thus showing good biological mineralization characteristics in simulated physiological solution and being used in the fields such as bone tissue repair and bone tissue engineering.
Owner:SOUTH CHINA UNIV OF TECH
Biomineralization-based acidic mine wastewater treatment system and treatment method
ActiveCN105601051AHigh synthesis efficiencyIncrease synthesisWaste water treatment from quariesTreatment using aerobic processesRefluxBiological oxidation
The invention provides a biomineralization-based acidic mine wastewater treatment system which comprises a water inlet end, a regulation unit, a biological oxidation mineralization unit, a lime neutralization unit, a lime dissolution unit, a neutralization residue reflux unit and a water outlet end. After the pH value of the acidic mine wastewater is regulated to 3.0, the acidic mine wastewater sequentially enters the biological oxidation mineralization unit and the lime neutralization unit to be treated, thereby reaching the discharge standard. By using the system and method provided by the invention, Fe<2+> in the acidic mine wastewater system can be completely oxidated within 48-60 hours, and meanwhile, the synthetic quantity of the secondary iron minerals can be enhanced by 30-60%. Compared with the conventional lime neutralization technique, the lime consumption is reduced by 30-50%.
Owner:SHANXI AGRI UNIV +1
Anti-infection mineralized collagen and calcium sulfate bone repair material and preparation method thereof
The invention belongs to the technical field of biomedical materials, and discloses an anti-infection mineralized collagen and calcium sulfate bone repair material and a preparation method thereof. The material is composite powder comprising 2-5wt% of mineralized collagen, 5-15wt% of vancomycin, 20-25wt% of calcium sulfate dihydrate and the balance alpha-type calcium sulfate hemihydrate. The alpha-type calcium sulfate hemihydrate is prepared by a hydrothermal method, the mineralized collagen is prepared by a biological mineralization method, and the alpha-type calcium sulfate hemihydrate, the mineralized collagen, the vancomycin and the coagulant calcium sulfate dihydrate are mixed to prepare the anti-infection mineralized collagen and calcium sulfate bone repair material with a certain component ratio. When the liquid / solid ratio is 0.5-0.8mL / g, the material has a fine self-setting performance, is degradable, slowly releases medicines, and is anti-infection. Besides, the material has fine biocompatibility and can promote adhesion and spreading of osteoblasts.
Owner:TSINGHUA UNIV +1
Anhydrous toothpaste repairing demineralized enamel and dentin and preparation method thereof
ActiveCN106511105ARaise the pHSmall apertureCosmetic preparationsToilet preparationsPhosphateApatite
The invention relate to anhydrous toothpaste containing water-soluble phosphate, micron-sized calcium carbonate and fluoride. The mass percent of water-soluble phosphate is larger than 2.0 wt%, the mass percent of micron-sized calcium carbonate is less than 40 wt%, the mass ratio range of water-soluble phosphate and micron-sized calcium carbonate is 1 / 10-5, and the mass concentration of fluorine of fluoride in the toothpaste is less than 8.0 wt%. When the anhydrous toothpaste containing water-soluble phosphate and micron-sized calcium carbonate is used, biological mineralization can be helped to be conducted on demineralized enamel and demineralized dentin slices, the enamel surface is repaired, the bore diameters of dental canaliculi on the dentin dental face is reduced, and even dentinal tubules are blocked. At the same time, fluoride is hydrolyzed to generate fluoride ions, the mineralization process of hydroxyapatite in teeth is promoted, and the repairing function of the toothpaste on enamel and dentin is improved.
Owner:HANGZHOU JIAOJIE ORAL HEALTH CARE PRODS
Hydroxyapatite/phase transformation lysozyme coating hybrid material and preparation method thereof
ActiveCN107115565AIncrease surface areaSimilar in structurePharmaceutical delivery mechanismTissue regenerationEnvironmental resistanceTissue repair
The invention discloses a hydroxyapatite / phase transformation lysozyme coating hybrid material and a preparation method thereof. The preparation method comprises the following steps: simulating biological mineralization in natural world, taking lysozyme as a protein template, chelating calcium ions onto the surface of a base material by utilizing functional groups abundant on the surface, then simulating a biological mineralization process in vitro by virtue of electrostatic interaction, successfully inducing nucleation of hydroxyapatite, and crystallizing, so that the hydroxyapatite / phase transformation lysozyme coating hybrid material which is similar to a natural bone in ingredient and structure is prepared. The hydroxyapatite / phase transformation lysozyme coating hybrid material is strong in mechanical stability, large in superficial area, good in biocompatibility and high in bone conductibility, can be taken as a tissue repairing material for guiding formation of a new tissue and induced mineralization of a bone, is expected to become a novel hard tissue substitute material and is simple in preparation process, mild in conditions, controllable in crystal morphology, environment-friendly and low in cost, so that the hydroxyapatite / phase transformation lysozyme coating hybrid material is applicable to preparation of hydroxyapatite on the surfaces of multiple base materials and has a broad application prospect.
Owner:SHAANXI NORMAL UNIV
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