1814results about How to "Diffusion fast" patented technology

The present invention generally relates to reducing the mucoadhesive properties of a particle. In some embodiments, the particle is coated with and / or associated with a (poly(ethylene glycol))-(poly(propylene oxide))-(poly(ethylene glycol)) triblock copolymer. Methods for preparing inventive particles using a poly(ethylene glycol)-vitamin E conjugate as a surfactant are also provided. In some embodiments, methods are provided comprising administering to a subject a composition of particles of the present invention. Such particles with reduced mucoadhesive properties are useful in delivering agents to mucosal tissues such as oral, ophthalmic, gastrointestinal, nasal, respiratory, and genital mucosal tissues.

Diagnostic dry reagent tests capable of reacting with a single drop of whole blood and reporting both glucose and beta-hydroxybutyrate levels are taught. Such dry reagent tests may employ electrochemical detection methodologies, optical detection methodologies, or both methodologies. These tests help facilitate the early detection of the onset of ketoacidosis in diabetes.

A zinc ion-exchanging battery device comprising: (A) a cathode comprising two cathode active materials (a zinc ion intercalation compound and a surface-mediating material); (B) an anode containing zinc metal or zinc alloy; (C) a porous separator disposed between the cathode and the anode; and (D) an electrolyte containing zinc ions that are exchanged between the cathode and the anode during battery charge / discharge. The zinc ion intercalation compound is selected from chemically treated carbon or graphite material having an expanded inter-graphene spacing d002 of at least 0.5 nm, or an oxide, carbide, dichalcogenide, trichalcogenide, sulfide, selenide, or telluride of niobium, zirconium, molybdenum, hafnium, tantalum, tungsten, titanium, vanadium, chromium, cobalt, manganese, iron, nickel, or a combination thereof. The surface-mediating material contains exfoliated graphite or multiple single-layer sheets or multi-layer platelets of a graphene material.

A method for encapsulating nucleic acids, particularly siRNAs, shRNAs, microRNAs, gene therapy plasmids, and other oligonucleotides in biodegradable polymers is disclosed, whereby the nucleic acids are formulated into reverse micelles composed of non-toxic and / or naturally-occurring lipids prior to nanoparticle formation by nanoprecipitation. This method can be coupled to other techniques that improve intracellular drug targeting, ultimately enhancing intracellular delivery of the aforementioned nucleic acids.

The present invention generally relates to reducing the mucoadhesive properties of a particle. In some embodiments, the particle is coated with and / or associated with a (poly(ethylene glycol))-(poly(propylene oxide))-(poly(ethylene glycol)) triblock copolymer. Methods for preparing inventive particles using a poly(ethylene glycol)-vitamin E conjugate as a surfactant are also provided. In some embodiments, methods are provided comprising administering to a subject a composition of particles of the present invention. Such particles with reduced mucoadhesive properties are useful in delivering agents to mucosal tissues such as oral, ophthalmic, gastrointestinal, nasal, respiratory, and genital mucosal tissues.

A safe and high-brightness LED lamp consists of a lampshade, a bulb mounting base, an LED module and a circuit board. The lampshade and bulb mounting base construct an inner space, which is allowable to store said LED module; the LED module consists of a heat-radiating block, an LED lamp panel and a reflective wall, where such LED lamp panel can be flat nestled up against the heat-radiating block at one end. Moreover, such reflective wall can be coupled with the LED lamp so that the said inner space can be partitioned into one light source refractive space and one flowing space for airflow thereof. Furthermore, an electrical fan is installed outside the heat-radiating block. Thereby, while light is being refracted and diffused via reflective wall into the light source refractive space in lampshade, it will then be refracted and diffused once more, and under this circumstance, not only the light will become more uniform with higher brightness, but also it will improve the heat radiation efficiency, and thus, resulting in a longer service life for such LED lamp while utilizing the said flowing space for airflow to guide the air blown by the fan.

The invention discloses a preparation method of a hydro-treatment catalyst. The preparation method comprises the following steps: preparing an alumina carrier, preparing an impregnation solution containing the VIII group metal and VIB group metal, wherein the impregnation solution comprises a proper amount of an organic auxiliary agent containing chelating ligand, then impregnating the alumina carrier into the impregnation solution under a proper ultrasonic treatment condition, and drying so as to obtain the hydro-treatment catalyst. The preparation method utilizes the ultrasonic cavitation effect to properly reduce the viscosity of the impregnation solution; at the same time the complexing capacity between the chelating ligand in the organic auxiliary agent and nickel / cobalt is improved by the catalytic function of the ultrasonic, the interaction force between the chelating ligand and nickel / cobalt is strengthened, thus the active metal component is promoted to highly disperse on the carrier surface, furthermore, the existing state of the active metal on the catalyst surface is improved at the same time, the sulfurization degree and sulfurization uniformity of the active metal are both improved, so the activity and stability of the catalyst are both improved. The catalyst is especially suitable for being used in the hydro-denitrogenation process and hydro-desulfurization process of heavy distillate oil.

A bi-layer silicon electrode and its method of fabrication is described. The electrode of the present invention comprises a lower polysilicon film having a random grain microstructure, and an upper polysilicon film having a columnar grain microstructure.

A charged glass raw material B is melted in a melting tank 10 by heating with a burner 31 and by heating with electrodes 12, to form molten glass G. Then, the molten glass G flows into a tank additionally provided as a noble gas dissolving tank 20 through a throat 40. The noble gas dissolving tank 20 is provided with a noble gas dissolving device 53, and the noble gas dissolving device 53 is provided with sixteen noble gas inlets 22 for introducing a helium or neon gas supplied to a hearth through heat resistant gas introduction tubes 21 into the noble gas dissolving tank 20. Bubbles of a helium gas A having a purity of 99% are blown out from the noble gas inlets 22 in volumes such that the bubbles have an average diameter of 80 mm or less in the molten glass G.

The invention relates to a graphene / MXene composite electrode material and application thereof. The graphene / MXene composite electrode material comprises two materials of graphene and MXene. A preparation method of the graphene / MXene composite electrode material comprises the steps of uniformly mixing a graphene oxide suspension liquid and an MXene material suspension liquid, adding hydrazine hydrate and the performing reduction, freezing and drying to obtain the graphene / MXene composite electrode material, wherein the mass ratio of graphene oxide and the MXene material is 1:(0.05-0.5). When graphene and MXene are combined, an irregularly-shaped MXene particle material can be used as an insertion agent and a dispersing agent and enters graphene sheet layers, the agglomeration effect amongthe graphene sheet layers is overcome, and the available specific area of the graphene / MXene composite electrode material is expanded; and moreover, the MXene material has excellent hydrophilcity andconductivity, and thus, the electrochemical performance and the capacitance deionization performance of the composite material can be further improved.

Disclosed is an optical fiber having a silica-based core comprising an alkali metal oxide selected from the group consisting of K2O, Na2O, LiO2, Rb2O, Cs2O and mixtures thereof in an average concentration in said core between about 50 and 500 ppm by weight, said core further comprising chlorine and fluorine, wherein the average concentration of fluorine in said core is greater than the average concentration of alkali metal oxide in said core and the average concentration of chlorine in said core is greater than the average concentration of alkali metal oxide in said core; and a silica-based cladding surrounding and directly adjacent the core. By appropriately selecting the concentration of alkali metal oxide dopant in the core and the cladding, a low loss optical fiber may be obtained.

The invention discloses a micro-needle array chip, which comprises a micro-needle and a substrate. The micro-needle consists of a needle head, a needle rod and a needle base; the top of the needle head is provided with a needle point; the micro-needle is fixed on the substrate through the needle base; the needle rod of the micro-needle is cylindrical or conical; the needle rod is inclined to the substrate at a set angle; and the needle head is conical or the upper surface of the needle point is an elliptical plane which is parallel to the substrate or inclined to the substrate at a set acute angle. The metal micro-needle in the micro-needle array chip is firm in structure and cannot rupture; the needle point is sharp and convenient to puncture; the maximum puncture depth of the micro-needle is easily regulated and controlled; the micro-needle in the array has good consistency and are safe and reliable to use; and the hollow micro-needle has a side opening similar to that of the traditional needle. Therefore, the micro-needle array chip can effectively avoid the phenomenon that the skin blocks the infusion hole, is more favorable for rapid diffusion and absorption of medicaments, and has obvious curative effect.

A preparation method for a flexible graphene-modified knittable carbon nanofiber belongs to the technical field of chemical industry. The preparation method comprises the following steps: at first, graphene oxide is taken to be placed in a container filled with DMF (Dimethyl Formamide) to obtain a graphene oxide saturated solution with the brown-yellow upper layer, then, polyacrylonitrile macromolecules are dissolved in the DMF to obtain a transparent macromolecular solution, the graphene oxide saturated solution and the macromolecular solution are mixed to obtain a precursor solution, a grapheme-modified polyacrylonitrile fiber is obtained through the electrostatic spinning technology or the melt spinning technology, the drying and stabilizing are performed, and at last, the carbon nanofiber is prepared from the dried polyacrylonitrile fiber in the inert gas environment or the vacuum condition. The carbon nanofiber prepared by the method can be applicable to lithium ion batteries or electrochemical capacitors, and besides, is also applicable to the fields of the war industry and the aerospace.

The invention discloses a preparation method of a catalyst facilitating highly selective synthesis of light olefins from syngas. A compound adopting a spherical or ellipsoidal structure is taken as a carrier to be loaded with iron oxide and added with auxiliaries and is used for Fischer-Tropsch reaction for the syngas. The catalyst has very high catalytic activity on one hand and can effectively reduce alkane generated through secondary reaction hydrogenation of light olefins, and the selectivity of light olefins is improved. The preparation method of the catalyst is simple, and the catalyst has very good application prospects.

An absorbent article is provided having an absorbent core with an absorbent pledget adhered to the body-facing side of the core between the core and the body-facing surface of the article. The pledget has a greater structural stiffness and a reduced surface area relative to the core. The absorbent article has a fluid permeable coverstock including a bi-component fiber. An hourglass-shaped absorbent pledget is disposed between the core and the coverstock. The pledget includes airlaid material adhered to the body-facing side of the absorbent core. The pledget further includes a three-dimensional apertured film mounted to the airlaid material, which engages the coverstock. The absorbent core is configured to fold about the hourglass shape of the pledget and resist undesired deformity of the absorbent article. The coverstock includes adhesive-coated elastic members disposed adjacent the longitudinal sides. The longitudinal sides are folded about a backsheet to enclose the core and pledget.

The invention discloses a modified polyester fiber prepared by carrying out blended spinning on functional copolyester master-batches containing moisture-absorbing radicals and inorganic nano-powder and conventional polyester chips, the section of the fiber is special-shaped and comprises micropores, the side surface of the fiber comprises a structure of longitudinal grooves and micro-pits, and a variety of fabric can be prepared by carrying out the blended spinning on the modified polyester fiber and natural fiber according to weight proportion. The fabric has the excellent functions of wetting by sweat, moisture transmitting and quick drying, thereby greatly improving the wearing comfort of the polyester fiber fabric.

A slow-release solid chemical composition for environmental bioremediation is provided. The composition comprises a source of soluble organic substrates which include sugars, soluble organic polymers and mixtures of them in an amount of 7% to 90%, insoluble organic substrates an amount of 10% to 70%, complex inorganic phosphates in an amount of 0.5% to 7% and soluble organic salts in an amount of 2% to 70%. The insoluble organic substrates include fibrous plant materials, starches, cellulosic materials and mixtures of these substrates. The complex inorganic phosphates include ringed metaphosphates, linear polyphosphates and mixtures. The organic salts include lactates, formates, acetates, citrates, etc. Also the composition further comprises microorganisms which include Bacillus spp., Rhizobium spp., Bradyrhibzobium spp., Fibrobacter spp., Clostridium spp., Pseudomonas. spp., Geobacter spp., Arthrobacter spp., Nocardia, spp., aspergillus spp., Trichoderma spp., Candida spp., Yarrowia spp. and combinations of these microorganisms. The composition can be prepared in various forms, including granules, briquettes, pellets, tablets or capsules.

The invention discloses a pre-lithiated and graphene-coated mesoporous SiO negative electrode material and a preparation method thereof. The method comprises the following steps: firstly, adding metal lithium to a non-aqueous solvent to form a lithium solution; secondly, adding graphene oxide to a dispersing solvent and carrying out ultrasonic treatment to obtain 0.5-60g / L of graphene oxide dispersion; adding nano mesoporous SiO microspheres with the specific surface area of 500-700m<2> / g to the dispersion, and carrying out ultrasonic treatment; adding the lithium solution under a stirring condition; adding a lithium complexing agent, stirring, filtering and washing to obtain a precursor; and finally drying the precursor in vacuum, grinding evenly, packing into a corundum boat, sintering in an inert atmosphere furnace, and cooling along with the furnace, so as to obtain the pre-lithiated and graphene-coated mesoporous SiO negative electrode material. The composite material is prelithiated in the process of preparing the graphene-coated mesoporous SiO negative electrode material; and the initial Coulomb efficiency, the cycle performance and the charge and discharge specific capacity of a silicon oxide negative electrode material are improved.

The invention discloses a method for electrochemically preparing graphene. The method comprises the following steps: 1, intercalating and expanding graphite paper by adopting graphite paper as a positive electrode and an aqueous intercalator solution as an electrolyte to obtain expanded graphite; 2, filtering and washing the expanded graphite, and carrying out ultrasonic peeling treatment on the expanded graphite to obtain a flocculent graphene slurry; and 3, filtering the graphene slurry, and drying the graphene slurry through adopting a microwave vacuum drier to obtain fluffy graphene powder. The electrochemical method solves the problem of use of heavy metal-containing reagents, strong acids, strong oxidants and expensive organic liquids in the graphene preparation process in the prior art, and has the advantages of simple preparation technology, low energy consumption and low cost.

Disclosed is a procedure to coat the free surface of Cu damascene lines by a 1-5 nm thick element prior to deposition of the inter-level dielectric or dielectric diffusion barrier layer. The coating provides protection against oxidation, increases the adhesion strength between the Cu and dielectric, and reduces interface diffusion of Cu. In addition, the thin cap layer further increases electromigration Cu lifetime and reduces the stress induced voiding. The selective elements can be directly deposited onto the Cu embedded within the under layer dielectric without causing an electric short circuit between the Cu lines. These chosen elements are based on their high negative reduction potentials with oxygen and water, and a low solubility in and formation of compounds with Cu.

A method and apparatus for the detection and quantification of very low levels of a target analyte using an imaging system is provided. In the case of some analytes such as certain hormones, for example TSH, their levels may be as low as several tens of thousands of molecules per micro liter. These extremely low levels can be measured by using the present invention to count the individual molecules of analyte. The invention also has the advantage of being a primary quantitative method, which is one which needs no standardization.

Zeolite microsphere FCC catalysts having a novel morphology comprising a macroporous matrix and crystallized zeolite freely coating the walls of the pores of the matrix. The catalysts are formed from microspheres containing a metakaolin and kaolin calcined through its exotherm, the latter calcined kaolin being derived from a kaolin having a high pore volume. Kaolin having a high pore volume can be a pulverized ultrafine kaolin or a kaolin which has been pulverized to have an incipient slurry point less than 57% solids.

The disclosed discharge switch includes upper and lower electrodes setup inside insulated case. Pressure inside the air locked shell body formed by the insulated case and flanges at two ends of the case is 10 -3 - 10 -4 Pa. At least one of the upper and lower electrodes is a movable electrode. Trigger electrode is inlaid inside the fixed electrode or setup between the upper and lower electrodes. Since being air locked in vacuum environment, the upper and lower electrodes possess tremendous ability of ducting transient current in high energy. Moreover, operation reliability of pulse switch is raised because vacuum environment is not interfered from outside. Features are: raised reliability, very low ablation rate of electrode, and wide range of stable operation voltage.

An alkaline battery separator which enables the preparation of a battery with a good yield and workability is provided. The alkaline battery separator of the present invention comprises a fiber sheet mainly comprising hydrophilicity-imparted polyolefin fibers having a fiber diameter of 8 mum or more, and a part of the hydrophilicity-imparted polyolefin fibers is composed of high-strength fibers having a tensile strength of 5 g / d or more.

The invention discloses a high-power-density membrane electrode for a proton exchange membrane fuel cell and a preparation method thereof. According to the method, the thickness of solid electrolyte is reduced, the thickness of a catalyst layer is reduced by using a high-content catalyst, and a nano-carbon tube or carbon fiber is introduced into a cathode catalyst layer and / or gas diffusion layer to improve mass transfer of the catalyst layer and the diffusion layer, so that the power density of a membrane electrode is greatly improved. The preparation method is simple in steps, is practical and feasible and is low in cost, can be used for reducing the thickness of the membrane electrode while improving the performance of the membrane electrode, and is favorable to preparation of high-power-density fuel cells, galvanic piles and systems.

The invention discloses a metallographic-phase aggressive agent of an austenitic stainless steel, a preparation method thereof and application thereof. The metallographic-phase aggressive agent comprises the mixed solution of hydrofluoric acid and nitric acid, calculated by volume ratio, the proportion of each component of the agent is that hydrofluoric acid : nitric acid : water is equal to 2 : 1 : 7. The preparation method thereof is carried out according to the following steps of: taking 70ml of water first, then taking 10ml of analytically pure nitric acid and finally taking 20ml of analytically pure hydrofluoric acid, which are then evenly mixed. The application method thereof comprises the following steps of: putting a simple of the austenitic stainless steel in the metallographic-phase aggressive agent of the austenitic stainless steel and observing the color change of the surface of the sample by time, taking out the sample of the austenitic stainless steel when metallographic-phase surface of the sample is corroded to darker silver gray, washing the sample with water which is then neutralized with alkaline solution and finally washing with water and absolute ethyl alcohol. The technical effects thereof are represented by good corrosion effect, clear austenite grain boundary, slow corrosion speed, easy control, no pollution and other aspects.

The present invention provides a method for expanding a trench in a semiconductor structure. A trench is provided in a semiconductor substrate, hydrogen-terminated silicon surfaces are provided in the trench, anisotropic wet etching of the silicon surfaces in the trench with an alkaline etchant occur, and the trench is rinsed with a proton-containing neutralizing agent for the removal of the alkaline etchant. Between the wet etching step and the rinsing step, an anodic passivation of the etched silicon surfaces in the trench is carried out, in the course of which an etching stop layer is formed on the etched silicon surfaces in the trench.

The invention relates to a micro-needle array chip, a transdermal delivery device, a transdermal delivery patch and a preparation method thereof, wherein a micro-needle is obliquely fixed on a substrate at a set angle, the upper surface of the needle is an elliptic plane parallel to the substrate or obliquely provided with an acute angle, the needle is further treated to have more edge angles, a metal wire bar or tube penetrates a non-metallic material substrate such as polymer and the like along a certain angle, and then a nick of the metal wire bar or tube on the substrate is grinded and polished; and photosensitive resist patterns are formed nearby the nick at one end by adopting photoetching and etching technology, then the metal wire bar or tube is subjected to chemical or electrochemical corrosion to form a needle point and the photosensitive resist is removed, the surface of the manufactured solid micro-needle array chip can be covered with drugs, and the manufactured solid micro-needle array chip can deliver liquid medicine or extract body fluid. The method avoids the skin plugging a transfusion hole, is easy to adjust and control the maximum penetrating depth of the micro-needle, and is suitable for percutaneous transportation of biological macromolecular drugs and cosmetics and skincare and new percutaneous preparation of the prior drugs.

A conductive material that includes a metal component consisting of a first metal and a second metal having a melting point higher than that of the first metal, wherein the first metal is Sn or an alloy containing 70% by weight or more of Sn, and the second metal is a metal or alloy which forms an intermetallic compound having a melting point of 310° C. or higher with the first metal and has a lattice constant difference of 50% or greater between itself and the intermetallic compound generated at the circumference of the second metal.