The invention relates to C45 mass concrete and a preparation process thereof, wherein the C45 mass concrete comprises: 140-170 parts of water, 250-300 parts of cement, 700-750 parts of sand, 335-380 parts of pebble, 700-800 parts of crushed stones, 80-100 parts of fly ash, 70-90 parts of mineral powder, 8-10 parts of a pumping agent, 35-45 parts of an anti-cracking agent, and 1-1.5 parts of a modifier. The preparation method comprises: 1, uniformly stirring sand, pebble, crushed stone and water to obtain an intermediate product; and 2, adding cement, fly ash, mineral powder, a pumping agent, an anti-cracking agent and a modifier, and uniformly stirring to obtain concrete. According to the technical scheme of the present invention, by simultaneously adding fly ash and mineral powder, the consumption of cement is reduced, such that the release rate of hydration heat is delayed, and the occurrence of shrinkage is reduced; and by adding the paraffin microcapsules, the temperature regulation effect can be achieved, such that the influence of the paraffin phase change volatilization on the environment can be avoided.