The embodiment of the invention discloses an operation control method for a M2M user equipment applied in machine to machine, which comprises the steps of: receiving information including operation instructions and sent from a network side, wherein the operation instructions comprise at least one of the instructions of indicating a user equipment UE or a group UE to register, activating signed data and transmitting business data; and operating the user equipment UE or the group UE according to the received operation instruction. The embodiment of the invention also provides corresponding user equipment, a corresponding server and a corresponding control system. In the embodiment of the invention, the user equipment is controlled by the network side to perform operation, the UE can be indicated to register, activate the signed data or transmit the business data at any time, the UE or the group UE can be in a dormant state or the state of going to register, and the impact and the influence from a large number of user equipment UE on the network side can be reduced so as to greatly improve the utilization ratio of network resources, meet the current M2M application and provide convenient and effective services for operators and users.