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127 results about "Superoxide radicals" patented technology

Superoxide dismutase is a protein that neutralizes free radicals. This protein is referred to as an enzyme, or as a protein that initiates or regulates a specific chemical or signaling action. Superoxide dismutase specifically neutralizes the superoxide radical, which is generated during normal aerobic processes.

Catalytic method for generating sulfate radicals and active oxygen species as well as advanced oxidation method of organic pollutants difficult to biodegrade

The invention provides a catalytic method for generating sulfate radicals and active oxygen species as well as an advanced oxidation method of organic pollutants difficult to biodegrade. The problemsof low degradation efficiency of organic pollutants and high cost in the prior art are solved. According to the catalytic method for generating sulfate radicals and active oxygen species, a transitionmetal oxyhydroxide-based material serves as a catalyst, and the sulfate radicals, hydroxyl radicals, superoxide radicals and singlet oxygen non-radicals are generated, so that the organic pollutantsdifficult to biodegrade are efficiently oxidized. The transition metal oxyhydroxide-based material serves as the catalyst, the activation efficiency of perosulfate is improved and various radicals andactive oxygen species are generated, so that the oxidative degradation rate of the organic pollutants is increased; and the catalyst has a stable structure, is low in heavy metal dissolution rate inthe catalytic process, avoids secondary pollution, and can be widely applied to treatment of industrial production waste water, treatment of domestic sewage, purification treatment of polluted underground water and surface water as well as treatment of polluted soil.
Owner:JILIN UNIV

Longan functional drink and method for preparing same

The invention relates to a longan functional drink and a method for preparing the same. The method comprises the following steps of: mixing desired longan pulp with other various raw materials and adding water to the mixture to a certain volume, boiling the mixture until the temperature is in the range of 80-100 DEG C, preserving heat for 20-40 minutes, grinding by using a pulp refiner until the particle granularity is about 15-20 microns, and filtering to obtain longan mixed juice; inoculating the longan mixed juice with sbacillus containing a manganese superoxide dismutase gene for fermentation culture; and keeping in cold storage, thereby obtaining the longan functional drink. The obtained longan functional drink is advantageous for improving the digestion absorption efficiency of the human body to food, improving the feeding of satiety after eating, reducing the possibility of abdominal distension exhaust, promoting normal defecation, reducing the pressure of the gastrointestinal tract, promoting vigor, promoting the health of the circulatory system, helping the body to adjust operation of the immunologic function and enhancing the human body defense mechanism; besides, the drink is advantageous for clearing away superoxide radicals generated in the human body and protecting the cells against damage, and has the characteristics of resisting aging and radiation, improving the tolerance of the cells to oxygen emergency reaction and the like.
Owner:JIMEI UNIV

Preparation method of antibacterial silver molybdate/MIL-101 (Fe, Zn) heterojunction photocatalytic membrane and product and application thereof

The invention provides a preparation method of an antibacterial silver molybdate/MIL-101 (Fe, Zn) heterojunction photocatalytic membrane and a product and application thereof. According to the preparation method, a heterojunction formed by compounding an inorganic antibacterial agent silver molybdate with broad-spectrum property and a bimetal organic framework compound MIL-101 (FE, Zn) is preparedinto the composite photocatalytic membrane by adopting an electrostatic spinning method. The product and use thereof are disclosed. The large specific surface area and rich active sites of MIL-100 (Fe) are fully utilized, interface charge transfer is effectively promoted, the separation capacity of photo-induced electrons and holes is improved, and adsorption and photocatalytic degradation removal of organic pollutants on the surface of the catalyst are promoted. Meanwhile, the surface of the silver molybdate is excited by illumination to generate superoxide free radicals and hydroxyl free radicals, so that the purposes of sterilization and bacteriostasis are achieved, the water treatment efficiency is effectively improved, the membrane pollution is reduced, the double-effect purificationof water quality is realized, the application prospect is relatively great, and a feasible scheme is provided for water pollution treatment.
Owner:SHANGHAI NAT ENG RES CENT FORNANOTECH

Cerium Oxide Nanoparticles for Treatment and Prevention of Alzheimer's Disease, Parkinson's Disease, and Disorders Associated with Free Radical Production and/or Mitochondrial Dysfunction

ActiveUS20090092671A1Reduce lossesDeter and prevent dopaminergic neuronal lossPowder deliveryBiocideMitochondrial diseaseLipid peroxidation
Cerium oxide nanoparticles (CeONP) can be used to treat or prevent neurodegenerative diseases, including for example Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, AIDS-related dementia, ALS, progressive supranuclear palsy, and encephalitis, as well as mitochondrial diseases and diseases associated with mitochondrial damage. In particular, CeONP having an average size of about 2 nm to about 100 nm can be administered in an amount sufficient to block production of hydroxyl or superoxide radicals, block free radical production by Aβ(1-42), block Aβ(1-42)-induced neuronal death, block Aβ(1-42)-induced [Ca2+]i dysfunction in neurons, block Aβ(1-42)-induced lipid peroxidation, decrease loss of dopaminergic neurotransmission, or reduce mitochondrial dysfunction in a cell. CeONP can also be effective in treating conditions involving toxic exposures to compounds that induce mitochondrial dysfunction, such as rotenone, cyanide, carbon monoxide, polychlorinated biphenyls (PCBs) and other mitochondrial toxins.
Owner:EDWARD VIA VIRGINIA COLLEGE OF OSTEOPATHIC MEDICINE

Preparation of superoxide dismutase modified vanadium nitride paste electrode sensor

The invention discloses a preparation method of a superoxide dismutase modified vanadium nitride paste electrode sensor, characterized by comprising the following steps: firstly preparing a nano VN / graphene compound paste electrode by adopting nano VN, graphene oxide and N-ethyl-3-picoline hexafluorophosphate; then modifying the nano VN / graphene compound paste electrode by adopting gamma-aminopropyl triethoxysilane, so as to obtain an aminopropyl triethoxysilane modified electrode; finally, dissolving bovine serum albumin and superoxide dismutase by adopting a phosphate buffer solution to prepare a superoxide dismutase immobilizing liquid; and then dripping the superoxide dismutase stationary liquid onto the aminopropyl triethoxysilane modified electrode, so as to prepare the superoxidedismutase modified vanadium nitride paste electrode sensor. The electrode has the advantages of being improved in conductivity in comparison with common carbon paste electrodes, wide in electrochemical window, simple in preparation method, low in cost, easy to update in surface, and small in residual current. A detection superoxide radical is high in sensitivity and good in selectivity.
Owner:UNIV OF JINAN

Osmium compounds for reduction of adverse inflammation

InactiveUS20050025805A1Reduce the possibilityReduction of the flux of nutrientsHeavy metal active ingredientsBiocideOsmium CompoundsCompound (substance)
Reduction of adverse inflammatory reaction to an implant or a transplant, or following trauma or infection, is achieved through catalysis of dismutation of the superoxide radical anion by an osmium containing compound. Treatment diseases caused by superoxide dismutase deficiency or mutation with superoxide radical anion dismutating osmium compounds or a carbonate radical anion decay catalyzing polymeric N-oxide is also disclosed.
Owner:ALPINE ELECTRONICS INC +1

Apparatus for treating pathological cells

An electromagnetic field generating apparatus for treating pathological cells, in particular with tumor suppression function. The ratio of static magnetic field to alternating magnetic field is in the range of 0.5-2.5, and the total intensity is in the range up to 100 mT. It provides non-invasive low toxicity and side effects, significantly inhibiting a plurality of tumors, influencing the intracellular superoxide radical content, and promoting cell autophagy. The mechanism of action of the magnetic field is on the electron spin energy levels and consequently on the free radicals concentration. Additional magnetic field having frequency up to 100 MHz and intensity down to microTesla range can be also used to improve the antitumor efficacy in combination with the static as well as the extremely low frequency electromagnetic field (1-300 Hz) influencing the spin hyperfine resonance. A combination method is also provided of a power-frequency electromagnetic field generating device and a platinum-based medicine. The in vitro and in vivo experiments confirmed that the tumor therapeutic electromagnetic field combined with platinum-based chemotherapy drugs can enhance the efficacy of platinum-based chemotherapy drugs and magnetic field alone, a significant inhibition of a variety of tumors; can reduce the dose of cisplatin and reduce side effects.
Owner:TOFANI SANTI +1

Preparation method of multivalent nanometer manganese oxide for effectively removing organic pollutants in water

The invention relates to a preparation method of a multivalent nanometer manganese oxide for effectively removing organic pollutants in water. The method comprises the following steps: preparing a medium by using yeast extract powder, acid hydrolyzed casein, glucose, HEPES, CaCl2, MgSO4, FeCl3 and trace elements (CuSO4, ZnSO4, CoCl2 and NaMoO4), adjusting the pH value to 6-8 by using 3M of NaOH, carrying out high temperature and high pressure disinfection, inoculating Pseudomonas sp.G7 according to 1%(V / V), carrying out shaking culture in a 20-30DEG C constant temperature culturing box for 20-30h, adding 0.3-0.5mM of a filtered and disinfected aqueous solution of MnCl2, continuously shaking for 12-15d, and washing the obtained precipitate with deionized water to obtain the multivalent nanometer manganese oxide. The above material has very good catalytic activity and stability, 2-chlorophenol converts to formic acid, acetic acid, oxalic acid and other micro-molecular organic acids in the degradation process, and the generation of a superoxide radical by the multivalent activated molecule oxygen of manganese is the main reason causing efficient degradation.
Owner:RES CENT FOR ECO ENVIRONMENTAL SCI THE CHINESE ACAD OF SCI

Method for fermenting red raspberry and grape enzyme by composite strain

The invention discloses a method for fermenting a red raspberry and grape enzyme by a composite strain. The method comprises cleaning red raspberries and grapes through sterile water under aseptic conditions, adding sterile water into a juicer, carrying out juicing, carrying out ultra-high temperature instantaneous sterilization on the mixed liquid, adding yeast and lactic acid bacteria into the mixed liquid subjected to sterilization, carrying out fermentation for five weeks, taking out the fermented enzyme supernatant, carrying out blending, adding sterile white granulated sugar syrup and honey into the supernatant and carrying out homogenization to obtain the red raspberry and grape enzyme. The red raspberries and grapes contain polyphenols and flavonoids and have oxidization resistance. The total phenol content, DPPH free radical scavenging ability, superoxide radical scavenging ability and ABTS radical scavenging ability in the fermentation process are gradually increased so thatantioxidant activity is significantly increased compared than that before fermentation. The raspberry and grape enzyme has good antioxidant properties.
Owner:SHENYANG INST OF TECH

Preparation method of organic pollutant photolysis catalyst

The invention discloses a preparation method of an organic pollutant photolysis catalyst. The preparation method is characterized by comprising steps as follows: regular ceramic is taken as carriers, are subjected to array hole formation with laser and activating treatment with potassium permanganate and then ultrasonically load sol-gel containing BiVO4, TiO2 and graphene, a product is subjected to vacuum drying and is subjected to high-temperature calcination finally, and industrial organic pollutant photolysis catalyst based on BiVO4-TiO2-graphene loaded regular ceramic is prepared. The photolysis catalyst can simultaneously release molecular radicals through plasma discharge and produce superoxide radicals and hydroxyl radicals through photocatalysis under radiation of a plasma emission (UV) light, thereby efficiently and thoroughly degrading toxic, harmful and stink industrial waste gas and industrial organic pollutants containing sulfur, nitrogen, ammonia, phenol, PAHs (polycyclic aromatic hydrocarbons), pesticides, antibiotics, viruses, bacteria and the like.
Owner:青岛海科绿邦环保科技有限公司

Mallotus furetianus homopolysaccharide as well as preparation method and application thereof

InactiveCN110229243AEfficient removalAntioxidant and inhibits α-glucosidase activityOrganic active ingredientsMetabolism disorderHomopolysaccharideStructural formula
The invention belongs to the technical field of natural polymers and discloses a mallotus furetianus homopolysaccharide with antioxidant activity and alpha-glucosidase inhibition activity as well as apreparation method and application thereof. The mallotus furetianus homopolysaccharide disclosed by the invention is named as MFP-2A, and the structural formula of the mallotus furetianus homopolysaccharide is as shown in the specification. The mallotus furetianus homopolysaccharide MFP-2A in the invention is an acid polysaccharide, simultaneously contains six glucosidic bonds of -4,6)-Galp-(1-,-3,6)-Manp-(1-,-5)-Araf-(1-,T-Araf-(1-,-4)-GalpA-(1- and -4)-Glc-(1-, particularly contains alpha-(1,4) glucosidic bonds, has high-efficiency abilities of scavenging DPPH (diphenyl-1-picrylhydrazyl) free radicals, ABTS (azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt) free radicals and superoxide radicals, also has properties of resisting oxidation and inhibiting alpha-glucosidaseactivity, can serve as a natural antioxidant, and is applied to preparation of hypoglycemic drugs or health foods.
Owner:SOUTH CHINA UNIV OF TECH +1

Nereis succinea antioxidant peptide and preparation method and application thereof

The invention puts forward a Nereis succinea antioxidant peptide and a preparation method and application thereof. The preparation method of the invention comprises the following steps: 1) taking liveNereis succinea, conditioning and pulping to obtain a serous fluid; 2) adding 600-1000 U / g of pepsase into the serous fluid, carrying out enzymolysis at 40-45 DEG C for 1-4 h, carrying out enzyme deactivation at 90-100 DEG C for 4-6 min, and cooling to obtain an enzymatic hydrolysate; and 3) carrying out coarse filtration on enzymatic hydrolysate, and carrying out fine filtration, ultrafiltration, concentration, desalination, purification and drying to obtain the Nereis succinea antioxidant peptide. The preparation method of the invention is simple, is convenient to operate, is green and environment-friendly, and is easy to realize industrialization. The Nereis succinea antioxidant peptide has high purity, strong activity and good antioxidant effect, has scavenging effect on DPPH free radicals, superoxide free radicals and hydroxyl free radicals, and has an obvious protective effect on oxidative damage of HUVEC cells. The Nereis succinea antioxidant peptide can be widely used in the production of nutritional food, functional food and feeds.
Owner:山东省海洋科学研究院青岛国家海洋科学研究中心

Carbon nanotube loaded CdSe-g-C3N4 photocatalytic material and preparation method thereof

The invention relates to the technical field of photocatalytic degradation of organic pollutants, and discloses a carbon nanotube loaded CdSe-g-C3N4 photocatalytic material and a preparation method thereof. The photocatalytic material comprises the following formula raw materials: cadmium chloride, sodium selenosulfate, urea, melamine and carbon nanotubes. According to the material and the preparation method thereof, the formation interface of CdSe and g-C3N4 has an overlapped energy band heterostructure with good matching performance; the heterostructure can effectively separate photo-generated carriers and transmit photo-generated charges, and the effective separation of photo-induced electrons and holes is enhanced, and therefore, a large number of freely moving photo-induced electronse<-> and holes h<+> are generated; the holes h<+> have very strong oxidability, the photo-induced electrons e<-> and dissolved oxygen in water can generate superoxide free radical O<2->., holes h<+> and superoxide free radical O<2->. have very high oxidation-reduction potentials and can be subjected to an oxidation-reduction reaction with various organic pollutants, so that the degradation efficiency of the photocatalytic material on organic dye pollutants is greatly improved.
Owner:王世扬

Composite nano material for air purification and preparation method thereof

The invention discloses a composite nano material for air purification and a preparation method thereof. The composite nano material is prepared from the following raw materials in parts by weight: 25 to 50 parts of composite nano particles, 15 to 30 parts of adsorption particles, 3 to 5 parts of hydroxyethyl methyl cellulose, 3 to 5 parts of lignocellulose and 10 to 15 parts of biomass glue. The preparation method comprises the following steps: mixing hydroxyethyl methyl cellulose, lignocellulose and biomass glue, then carrying out hydrolytic condensation to prepare sol, sequentially adding composite nano particles and adsorption particles, carrying out uniform-speed stirring for 30 min, then carrying out evaporation and dehydration to prepare gel, and then carrying out drying and heat treatment to prepare the composite nano-material for air purification. When the composite nano particles are used, visible light can excite indium vanadate to generate electrons, the electrons are transferred to the surfaces of the composite nano particles, the electrons and oxygen molecules adsorbed on the surfaces are combined to form superoxide free radicals, then the superoxide free radicals and organic pollutants adsorbed on the surfaces of the composite nano particles are subjected to an oxidation-reduction reaction, and the air purification effect of the composite nano particles is further improved.
Owner:张娟丽
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