The invention discloses a method for synthesizing laurel acyl
amino acid sodium. The method comprises the steps that
lauric acid and
phosgene react by being catalyzed by organic
aryl amide, and lauroyl
chloride is prepared; lauroyl
chloride and
amino acid react in an alkaline solution, and lauroyl
amino acid salt is prepared; extraction separation is carried out, a catalyst is recycled from an organic phase, a water phase is sequentially subjected to acidification, filter separation,
sodium hydroxide neutralizing and cooling
crystallization, and laurel acyl amino acid
sodium is obtained. According to the method, organic
aryl amide is mainly adopted as the catalyst for the reaction of
lauric acid and
phosgene, the
lauric acid acylation reaction is thorough, no residue exists,
acyl chloride products do not need layering, distilling and other purifying processes can be directly used for synthesizing laurel acyl amino acid sodium, and especially the catalyst can be recycled and cyclically utilized through a simple method. Compared with use of existing DMF and other
fatty amine catalysts, the process steps are greatly simplified, the yield and quality of the product are improved, production cost is reduced,
environmental protection is facilitated, and the requirements of industrial production are met.