The invention discloses a rhodium reduction activation dissolution method, and relates to the technical field of noble metal metallurgy. The rhodium reduction activation dissolution method can be used for overcoming the defects of the prior art and aims at achieving a rhodium dissolution method which has the advantages of high dissolution efficiency, wet method normal-pressure dissolution, easiness for operation, short process flow, low production cost and wide rhodium waste dissolution range. The technical scheme is as follows: the rhodium reduction activation dissolution method comprises the following steps of: A, crushing and grinding rhodium wastes; B, mixing with an activating agent; C, carrying out acid-soluble activation; D, filtering; and E, dissolving. According to the invention, because zinc powder and a hydrochloric acid solution generate chemical reaction in the step C to generate H2, rhodium oxide contained in the solution can be reduced into metal rhodium through H2 at 100 DEG C, the dissolution activity of rhodium can not be reduced and can be enhanced so as to be favorable to subsequent dissolution, and the rhodium oxide is reduced into the metal rhodium without being dissolved by hydrochloric acid in the activated process. Thus, the rhodium reduction activation dissolution method disclosed by the invention has the advantages of high rhodium dissolution efficiency, rhodium normal-pressure dissolution, low dissolution temperature, easiness for operation, short process flow, low production cost and wide rhodium waste dissolution range.