44results about How to "Broad cracking spectrum" patented technology

The invention discloses a coliphage B_EcoM_C1 with the preservation number of CCTCC NO:M 2017190. The coliphage B_EcoM_C1 is a double-stranded DNA, belongs to a myovirus family, having a regular dodecahedron-shaped head and a telescopic tail, and can form a transparent and bright plaque on a solid medium, no aureoles exist surrounding the plaque, the plaque has clear and regular edge, and the diameter is 0.5-1 mm. The coliphage B_EcoM_C1 has a good eliminating and killing effect on enterohemorrhagic Escherichia coli in the space environment, and especially mcr-1 positive enterohemorrhagic Escherichia coli, and can be applied to the preparation of medicines for controlling the enterohemorrhagic Escherichia coli infection in order to realize a broad-spectrum sterilization effect.

The invention discloses a high-temperature-resistant potent proteus phage RDP‑SA‑20018, the preservation number is CGMCC No.21405, the full length of the gene is 42626bp, and it is found after sequencing the whole gene that it does not have virulence genes and lysogenic genes, The Proteus phage RDP‑SA‑20018 provided by the present invention has higher temperature tolerance and wider acid-base tolerance range, which is conducive to industrial production and preparation; it is found by lysis rate experiment and RTD experiment that the lysis of the bacteriophage The rate is 98%, and it still has a good cracking effect on pathogenic bacteria. The phage has the characteristics of excellent performance and safety. The phage can be used in the preparation of medicines for preventing and or treating diseases caused by proteus.

The invention belongs to the technical field of microbial control, and in particular relates to a combination of Vibrio parahaemolyticus phage VP-HYP MCS-1 and Halobacteriovorax sp.MCS-1 and their use in preventing and treating pathogenic Vibrio parahaemolyticus infection of prawns. application. The phage of Vibrio parahaemolyticus is the phage of Vibrio parahaemolyticus VP-HYP MCS-1, which has been deposited in the General Microbiology Center of the China Microorganism Culture Collection and Administration Commission, and the preservation number is CGMCC No.19693. Vibrio parahaemolyticus is Vibrio parahaemolyticus Halobacteriovorax sp.MCS‑1, which has been deposited in the General Microbiology Center of the China Microorganism Culture Collection and Management Committee, and the preservation number is CGMCC No.19694. The virulent bacteriophage VP-HYP MCS-1 isolated and obtained by the present invention has strong host specificity and has the functions of lysing and killing Vibrio parahaemolyticus; the isolated and obtained leech vibrio Halobacteriovorax sp.MCS-1 has a wide host spectrum , has the effect of lysing and killing a variety of Vibrio including Vibrio parahaemolyticus; the Vibrio parahaemolyticus bacteriophage and leech vibrio provided by the present invention have good performance in preventing and controlling pathogenic Vibrio parahaemolyticus infection of prawns application prospects.

The invention discloses a bdellovibrio bacteriovorus for preventing and curing rice bacterial diseases and application thereof. The invention can obtain bdellovibrio bacteriovorus BDFM05 by separation and ultraviolet mutation. The bdellovibrio bacteriovorus BDFM05 is combined with oligosaccharide to obtain bdellovibrio bacteriovorus for preventing and curing crop bacterial diseases. The inventionapplies bdellovibrio bacteriovorus BDFM05 to prevent and cure crop bacterial diseases for the first time. The bdellovibrio bacteriovorus prepared by the method has better rice bacterial diseases preventing and curing effect than common Saisentong, has no toxicity or pollution, is safe to natural enemies of crop diseases and pests, produces no pathogenic bacteria resistance, has no toxic or side effects to people and animals, improves the quality and safety of agricultural products and conforms to the requirements of people on healthy and green food and sustainable-development for agriculturalproduction.