The invention relates to a glitter powder noctilucent heat transfer printing ribbon. The glitter powder noctilucent heat transfer printing ribbon is composed of a base membrane, a heat-resisting back coating applied to one face of the base membrane, a releasing layer and an ink layer, wherein the releasing layer and the ink layer are applied to the other face of the base membrane. The thickness of the releasing layer ranges from 1.4 micrometers to 1.8 micrometers. The releasing layer is prepared from, by mass percent, 10-20% of a binder, 35-55% of wax and 30-45% of noctilucent powder. The thickness of the ink layer is controlled within 1.6-2.0 micrometers. The ink layer is prepared from, by mass percent, 10-20% of a binder, 20-35% of wax, 5-15% of pigment, 35-45% of glitter powder and 3-8% of an auxiliary. The glitter powder noctilucent heat transfer printing ribbon has the beneficial effects of being convenient to use, clean, free of contamination, economical and applicable, and meanwhile, on the aspect of performance, the glitter powder noctiluent heat transfer printing ribbon has the excellent characters of being high in transfer printing definition, high in recognition for naked eyes on visible light reflection, visible at night, high in scraping resistance, low in noise, high in blackness, free of powder falling of the coatings, and has relatively good application and popularization value.