61results about How to "Achieve slow release" patented technology

The invention discloses a slow-release carbon source material using sodium alginate as a base material and a preparation method of the slow-release carbon source material, and belongs to the technical field of water treatment. The slow-release carbon source material disclosed by the invention comprises the following ingredients in parts by weight: 5 parts of starch, 4 to 8 parts of sodium alginate and 2 to 6 parts of calcium chloride (CaCl2). According to the slow-release carbon source material, the sodium alginate is used as a carrier of a fixed carbon source, the starch is used as a carbon source, the materials are jointly dissolved in water to obtain mixed solution, CaCl2 solution is used as a crosslinking agent, the mixed solution is dripped into the crosslinking agent through an injector and is crosslinked for 20 to 30 hours in the crosslinking agent, and the slow-release carbon source material can be used through being cleaned by pure water. The slow-release carbon source material disclosed by the invention has the advantages that the carbon source can be slowly released, the carbon source is provided for the denitrification denitrifying process, the slow release places can also be provided for microorganisms, and the denitrifying effect is enhanced.

The invention provides a microcapsule containing dimethyl phthalate, mosquito repellent water and a preparation method thereof. The microcapsule disclosed by the invention comprises dimethyl phthalate, chitosan and gamma-polyglutamic acid. The dimethyl phthalate is coated by utilizing chitosan and polyglutamic acid and is separated from skin, so that irritation to skin is reduced, slow release of the mosquito repellent is realized, and then a mosquito repellent effect is lasting. The mosquito repellent water disclosed by the invention comprises the following main components: the microcapsule containing dimethyl phthalate, aloe extract, hyaluronic acid, polyethylene glycol, propylene glycol, rose hydrosol, water and the like, has the effects of moisturizing, resisting bacteria, diminishing inflammation, relieving itching and the like and is safe and non-toxic. The microcapsule is simple in preparation process, and the wall material has renewability and biodegradability and is non-irritating to skin. According to the mosquito repellent water disclosed by the invention, the dimethyl phthalate is separated from the skin by utilizing the microcapsule, so that bad reactions are reduced; and moreover, a slow release aim of the dimethyl phthalate is achieved, the concentration of the dimethyl phthalate in toning lotion can be reduced, and the effective mosquito repellent time is prolonged.

The invention relates to a method for compounding and entrapping tea polyphenols through debranched starch and xanthan gum. The method comprises the following steps of (1) making starch raw materials into starch milk and performing sufficient gelatinizing; (2) lowering the temperature to the appropriate temperature of debranching enzymes, adding the debranching enzymes for enzymolysis, and then performing ion exchange, decoloring and concentration on enzymatic hydrolysate; (3) enabling the xanthan gum to dissolve in the water, and performing compounding with the concentrated enzymatic hydrolysate of the debranched starch; (4) maintaining the temperature of a compounding system solution to be 70-80 DEG C, maintaining the temperature to be the temperature range, under the stirring condition, adding the tea polyphenols, and performing uniform stirring; and (5) uniformly stirring the solution, then sending the uniformly-stirred solution into a high-pressure homogenizer for homogenizing for several times, then sending the homogenized solution into a spray drying system, and under the condition of being away from light, performing stirring and spray drying at the same time so as to obtain tea polyphenol microcapsules. The method is simple to operate, the starch is used as a main raw material, and through compounding with the xanthan gum, so that the stable state of the tea polyphenols is realized; and the tea polyphenols can be slowly released in the digestive tract of human bodies, so that the bioavailability of the tea polyphenols is improved, and the application range of the starch is extended.

The invention discloses a starch-based steady-state vegetable oil compound and a preparation method thereof. The preparation method comprises the following steps: (1), adding waxy starch with the molecular weight of 6000-10000 kda into water, and performing heating and stirring for complete gelatinizing to obtain a solution A; (2) adding gelatin into water, and performing heating for dissolving toobtain a solution B; (3) adding the solution A into the solution B, performing cooling and uniform stirring, adding a stabilizer, and performing shearing and homogenizing to obtain a water-in-water Pickering emulsion; (4) cooling the Pickering emulsion to swell the solution A and the solution B to form hydrogel, performing dialyzing in water to remove gelatin, and performing precipitating and drying with ethanol to obtain porous starch; and (5) mixing the vegetable oil with the porous starch, performing quick stirring, and carrying out vacuum drying to obtain the starch-based steady-state vegetable oil compound. The slow release of the vegetable oil is realized, the bioavailability is improved, and the oxidation reaction is effectively inhibited.

The invention belongs to the technical field of pharmaceutical preparations, and particularly discloses a sulfadiazine silver thermo-sensitive hydrogel and a preparation method thereof. The hydrogel includes sulfadiazine silver, gelatin, a thermo-sensitive gel matrix, emodin, chitosan, collagen, a temperature regulator, and a humectant. The sulfadiazine silver is micronized to enlarge the surfacearea of particles so as to enhance the antibacterial effect. The method uses the sulfadiazine silver and the emodin as main drugs, the gelatin as a carrier, then uses the thermo-sensitive gel matrix,the temperature regulator, the chitosan and the collagen to prepare a thermo-sensitive hydrogel substrate, and finally encapsulates the sulfadiazine silver and the emodin in the hydrogel substrate soas to form the new sulfadiazine silver thermo-sensitive hydrogel. The hydrogel is an aqueous gel preparation which can be applied to burn and scald wound infection, and has good antibacterial effect,high efficiency and low toxicity, and high compliance for patients.

The invention relates to the technical field of medicines, and especially relates to a preparation method and application of a disulfiram-loaded nano-emulsion in-situ gel. The preparation method comprises the following steps: (1) mixing an oil phase, an emulsifier and a co-emulsifier, adding polyethylene glycol-modified phospholipid, and uniformly mixing to obtain a first mixed solution; (2) adding disulfiram into the first mixed solution, and obtaining a second mixed solution after the disulfiram is completely dissolved; and (3) adding ultrapure water containing an in-situ gel agent into thenano-emulsion, and carrying out self-assembly to obtain the disulfiram-loaded nano-emulsion in-situ gel. According to the disulfiram-loaded nanoemulsion in-situ gel, the solubility of disulfiram is remarkably improved, an ideal slow release effect is achieved, the in-vivo stability of disulfiram is improved, high safety is achieved, and the characteristic of remarkable brain enrichment during nasal administration is achieved.

The invention discloses a scale and corrosion inhibition microcapsule and a preparation method thereof, and belongs to the technical field of water treatment agents. According to the scale and corrosion inhibition microcapsule and the preparation method thereof, polyacrylamide and 2,3-diaminonaphthalene are used in a corrosion inhibition component and have a synergistic effect so that the corrosion inhibition effect can be greatly improved; introduced secondary alkane sulphonate sodium can improve the biodegradability of the polyacrylamide, is a green surfactant and also has the effect of inhibiting the growth of bacteria, so that the use amount of a bactericide can be decreased, and the circulating water treatment cost can be lowered; halogen ions in hydrogen bromide generate specific adsorption on the metal surface to enable the metal surface to carry a negative charge, and molecules, which are beneficial to protonation, of two organic corrosion inhibitors, namely the polyacrylamideand the 2,3-diaminonaphthalene are adsorbed on the metal surface, and therefore the corrosion inhibition effect of the corrosion inhibitors can be improved; and the problems that a scale and corrosioninhibitor commonly used in the existing market needs to be firstly dissolved into an aqueous solution during water treatment, then the aqueous solution is added into water for water treatment, the operation is complex, and secondary environmental pollution can be caused can be solved.

The invention provides a microcapsule containing dimethyl phthalate, mosquito repellent water and a preparation method thereof. The microcapsule disclosed by the invention comprises dimethyl phthalate, chitosan and gamma-polyglutamic acid. The dimethyl phthalate is coated by utilizing chitosan and polyglutamic acid and is separated from skin, so that irritation to skin is reduced, slow release of the mosquito repellent is realized, and then a mosquito repellent effect is lasting. The mosquito repellent water disclosed by the invention comprises the following main components: the microcapsule containing dimethyl phthalate, aloe extract, hyaluronic acid, polyethylene glycol, propylene glycol, rose hydrosol, water and the like, has the effects of moisturizing, resisting bacteria, diminishing inflammation, relieving itching and the like and is safe and non-toxic. The microcapsule is simple in preparation process, and the wall material has renewability and biodegradability and is non-irritating to skin. According to the mosquito repellent water disclosed by the invention, the dimethyl phthalate is separated from the skin by utilizing the microcapsule, so that bad reactions are reduced; and moreover, a slow release aim of the dimethyl phthalate is achieved, the concentration of the dimethyl phthalate in toning lotion can be reduced, and the effective mosquito repellent time is prolonged.

The invention belongs to the field of microbial fertilizers, and particularly relates to a double-network hydrogel shell polycystic core structure trichoderma harzianum agent as well as a preparationmethod and application thereof. The preparation method comprises the following steps that trichoderma harzianum, bacterial cellulose, soluble starch, calcium carbonate and other powder are uniformly mixed to prepare a fungicide core layer; a polyvinyl alcohol film is attached to the surface of the fungicide nuclear layer, so that the fungicide nuclear layer is isolated from the external environment; then coating with a nutrition synergist represented by glucose, ammonium sulfate, monopotassium phosphate and the like is peformed; and finally, a polyvinyl alcohol-glycerol / gelatin double-networkhydrogel shell layer on the surface of a nutrition synergistic layer. According to the method, the trichoderma harzianum agent with low bacterial powder encapsulation amount and high viable bacteriumrelease amount can be obtained.

The invention discloses a preparation method of a new biomaterial based on lactoferrin activity. The lactoferrin having osteogenic activity is applied to the bone tissue engineering field as a new bone growth factor, so the problems of difficult obtaining and high prices of various bone growth factor are solved. Lactoferrin is loaded on a hydroxyapatite / collagen implant material, and the interaction between the lactoferrin and hydroxyapatite / collagen composite material is used to realize the slow release of the lactoferrin and solve the problem of short half-life of the supported growth factor. The osteogenic activity of the hydroxyapatite / collagen implant material is improved to a certain degree, and the problem of low bioactivity of a single biomaterial is solved.

The invention discloses an insect sex pheromone micro-capsule based on a multiwalled carbon nanotube. The micro-capsule is composed of a capsule wall and a core material. The multiwalled carbon nanotube is used for making the capsule wall, and the core material comprises insect sex pheromones (Z,E)-9,12-tetradecadienyl acetate or (Z,E)-9,11-tetradecadienyl acetate. The multiwalled carbon nanotube has a special seamless hollow nanoscale coaxial cylinder structure and has a larger specific area and higher loading capacity. The multiwalled carbon nanotube is used for making the capsule wall, the loading capacity of the insect sex pheromones can be larger, slow release of the insect sex pheromones in the micro-capsule can be achieved, the lasting, efficient and stable pest trapping and killing effect is achieved, and storage stability is improved. Meanwhile, the dosage of an organic solvent is small in the preparation process of the micro-capsule, environmental pollution caused in the use process can be avoided, and the micro-capsule is an efficient and environment-friendly material.