46 results about "Sulfadiazine Silver" patented technology

One kind of porous bacteriostatic polyelectrolyte material suitable for stopping bleeding and dressing wound is disclosed. The material features that it is prepared with chitosan solution in 1-5 wt% concentration and sodium alginate solution 1-5 wt% concentration in the weight ratio of 0.25-4 as material and through mixing and freeze drying. The chitosan solution is prepared through dissolving chitosan in water solution of acetic acid. The material includes also sulfadizine silver or PVP-iodine bacteriostatic agent in the amount of 3-10 wt% of chitosan and sodium alginate. The porous material has no toxicity, relatively great pores, high water absorption rate and short bleeding stopping period.

Biocidal compounds have been synthesized and tested by the invention. These biocidal compounds have broad-spectrum efficacy and their biocidal properties are easily renewable. Illustrative examples of these biocidal compounds include N-halamine monomers and polymers and silver sulfadiazine polymers. These compounds can be used to add biocidal function to various materials and articles.

The invention discloses a nanometer antibiotic composite material of polymer / montmorillonite-soya bean lecithin-silvadene, which comprises the following parts: 100g polymer, 0.1-10g montmorillonite-soya bean lecithin-silvadene composition, 0-400g dispersing dielectric, 0-10g crosslinking agent and 0-1g accelerant, wherein the polymer is composed of raw rubber of silicon rubber, polyurethane or two copolymer or polyolefin material; the raw rubber of silicon rubber is selected from indoor-temperature silicon rubber, high-temperature silicon rubber, addition-typed silicon rubber; the polyolefin material can be PE, PVC, PP; the ion exchange content of montmorillonite is 70-120mmol / 100g.

The invention discloses a suspension preparation of temperature change painless nano sulfadiazine metallic compound hyaluronic acid. The formula comprises a sulfadiazine metallic compound, a hyaluronic acid substance, an analgetic, a dispersing agent aid, a suspension aid and water, wherein the sulfadiazine metallic compound comprises sulfadiazine silver and sulfadiazine zinc; the hyaluronic acid substance is sourced from biological fermentation and animal tissue extraction and the like and can be hyaluronic acid or hyaluronate or crosslinked hyaluronic acid or crosslinked hyaluronate; the analgetic comprises ropivacaine, bupivacaine, levobupivacaine, lidocaine and other local anesthetics or combination of the local anesthetics; the dispersing agent aid comprises chlorhexidine, Tween series, oleic acid or sodium oleate; the suspension aid can comprise glycerinum, celluloses, poloxamer series and hyaluronic acid substances. The suspension preparation is mainly used for burn, scald or the surface of a wound caused by explosion or anabrosis, has the main clinical characteristics that pain is rapidly relieved, the surface of the wound is subjected to rapid film formation and rapid healing of the wound is promoted, and the conventional main administration modes refer to spraying, smearing and coating.

A compound sulfapyrimidine silver zinc ointment for treating burn is prepared from sulfapyrimidine silver, sulfapyrimidine zinc, osmotic aid medical auxiliary, ethyl p-hydroxybenzoate, glycerine and distilled water through heating oil phase to 75 deg.C, heating water phase to 75 deg.C, slowly adding oil phase to water phase while stirring, cooling, adding sulfapyrimidine silver and sulfapyrimidine zinc, grinding, and examining. Its advantage is strong antibacterial function.

The invention discloses an antibacterial hemostatic sponge. The antibacterial hemostatic sponge comprises hyaluronic acid, polyvinyl alcohol, collagen, silk fibroin powder, chitosan, glycerin and sulfadiazine silver salt. The antibacterial hemostatic sponge which is a porous composite material has the advantages that the antibacterial hemostatic sponge is good in biocompatibility, dialysis performance, blood absorption performance, antibacterial performance, adhesion resistance and mechanical performance and high in use comfortableness, and the used sulfadiazine silver salt effectively increases the antibacterial performance of the sponge and reduces probability of wound infection.

The invention discloses sulfadiazine silver controlled-release gel which is prepared by the following method: (1) evenly mixing sulfadiazine silver and sodium alginate aqueous solution into a suspension in darkness, pouring the suspension onto a glass plate mold to make same naturally and smoothly flow, freezing and unfreezing at the room temperature in darkness; (2) adding calcium chloride to water-soluble chitosan solution, and fully mixing until the calcium chloride is dissolved to obtain the water-soluble chitosan-calcium chloride mixture; and (3) immersing the prepared product in step (1) in the water-soluble chitosan-calcium chloride mixture, holding, removing the glass plate mold and rinsing to obtain the sulfadiazine silver controlled-release gel. The sulfadiazine silver controlled-release gel of the invention has good biocompatibility and achieves the effects of stopping bleeding and helping healing; and the sulfadiazine silver controlled-release gel achieves good effect of moisture preservation and is favorable for healing the wound surface and easily applied and removed, thus relieving the pain of the sick and wounded caused by secondary wound.

A medicine "Sulfapyrimidine silver-crustamine" in the dosage form of powder contains sulfapyrimidine silver (0.5-2 wt. portions), crustamine (1-50) and polyvinyl alcohol (50-150). Its advantages are high stability and antibacterial effect, and high wound-healing speed.

The invention provides a preparation method of composite hyaluronic acid-sulfadiazine silver gel. The preparation comprises hyaluronic acid and sulfadiazine silver and the preparation is prepared by dissolving hyaluronic acid at high temperature and adding the dissolved hyaluronic acid in sulfadiazine silver. The composite hyaluronic acid-sulfadiazine silver gel of the invention has good biocompatibility and long half-life, thus being applicable to all kinds of antipyrotic and antibacterial situations.

The invention relates to a preparation method for a compound silver-contained antibacterial dressing. The preparation method is characterized in that the antibacterial dressing comprises natural polymer materials and sulfadiazine silver; the natural polymer materials are taken as the raw materials to produce a composite fiber cavernosum material through a freeze drying technology; and the sulfadiazine silver is loaded on the cavernosum. According to the preparation method, the silver-contained antibacterial dressing is prepared through the freeze drying technology and by loading silver on the cavernosum through spraying, has good biocompatibility, and can maintain a moist environment for a wound surface to facilitate occlusion of wounds and regeneration of skin; and the antibacterial component of the silver-contained antibacterial dressing is sulfadiazine silver which has a very good sterilizing property and a wide antibiotic spectrum, so that the silver-contained antibacterial dressing can provide a favorable condition for a wound surface and guarantee quick occlusion of wounds, and has a simple production technology and an extensive application prospect.

The invention discloses an antibacterial warm-keeping chemical fiber fabric and a preparation method thereof. The antibacterial warm-keeping chemical fiber fabric is prepared from antibacterial warm-keeping composite fibers through a knitting or weaving process. The antibacterial warm-keeping composite fiber is prepared from the following raw materials in parts by weight: 70-80 parts of ethylene glycol terephthalate, 18-24 parts of polyacrylonitrile, 7-10 parts of polyurethane elastomer, 1.8-2.2 parts of sulfadiazine silver, 2.3-2.8 parts of chitosan quaternary ammonium salt, 3-4 parts of calcium silicate nanosheets, 2.2-2.6 parts of silicon dioxide aerogel and 3-5 parts of processing aid. The antibacterial warm-keeping chemical fiber fabric is high in antibacterial rate and has a good antibacterial effect; the antibacterial warm-keeping chemical fiber fabric is good in warmth retention property, comfortable to wear and warm; the breaking strength is high and the mechanical property is good; and in addition, the antibacterial warm-keeping chemical fiber fabric is soft in hand feeling, good in elasticity and comfortable to wear.

The invention belongs to the technical field of pharmaceutical preparations, and particularly discloses a sulfadiazine silver thermo-sensitive hydrogel and a preparation method thereof. The hydrogel includes sulfadiazine silver, gelatin, a thermo-sensitive gel matrix, emodin, chitosan, collagen, a temperature regulator, and a humectant. The sulfadiazine silver is micronized to enlarge the surfacearea of particles so as to enhance the antibacterial effect. The method uses the sulfadiazine silver and the emodin as main drugs, the gelatin as a carrier, then uses the thermo-sensitive gel matrix,the temperature regulator, the chitosan and the collagen to prepare a thermo-sensitive hydrogel substrate, and finally encapsulates the sulfadiazine silver and the emodin in the hydrogel substrate soas to form the new sulfadiazine silver thermo-sensitive hydrogel. The hydrogel is an aqueous gel preparation which can be applied to burn and scald wound infection, and has good antibacterial effect,high efficiency and low toxicity, and high compliance for patients.

The invention relates to a material for multifunctional power maintenance gloves. The material comprises the following components: hexaflumuron, Carbomer, pine tar, boiled tung oil, ethylamine, isothiazolinone, styrene-maleic anhydride copolymers, p-tert-octyl phenol formaldehyde resin, methyl MQ silicone resin, polystyrene resin, arabinogalactan, amino-oligosaccharin, acrylic acid-2-ethyl hexyl ester, clove oil, ethyl p-hydroxybenzoate, dimethyl hydroxyl silicone oil, diisoamyl ether, ammonium chromate, barium peroxide, sulfadiazine silver, poly(butylene succinate), sodium polymethacrylate, trimethyl phosphate, sodium hexametaphosphate, chlorinated polyethylene, morpholine, nano-alumina powder, citric acid, glucose, sorbitol and carboxymethylcellulose. The product prepared from material has excellent flame retardance, acid-base resistance, mildew resistance and mold resistance, and the performance of the product is improved.

The invention provides a method for synthesizing medicinal sulfadiazine silver. The method comprises the steps of allowing silver nitrate solution and sulfadiazine sodium solution which are fed and stirred simultaneously to react in a reaction tank, standing, draining, centrifugally drying and obtaining a sulfadiazine silver product, wherein the synthesis reaction temperature of silver nitrate and sulfadiazine sodium is 45 to 55 DEG C, and trifluoromethanesulfonic acid (salt) catalysts are used in the process of utilizing sulfadiazine powder and sodium hydroxide to prepare the sulfadiazine sodium.

The invention relates to compound argentiferous antimicrobial dressings which are characterized in that the antimicrobial dressings are formed by natural macromolecule materials and sulfadiazine silver; the natural macromolecule materials are used as main raw materials, composite fibre sponge body materials are produced by means of utilization of freeze drying technique, and the sulfadiazine silver is loaded on the sponge body to form the antimicrobial dressings; and by means of the utilization of the freeze drying technique and by means of spray coating, the sulfadiazine silver is loaded on the sponge body to form the antimicrobial dressings. The antimicrobial dressings are good in biological compatibility and favorable for wound healing and skin regeneration, and maintain a moist environment for a wound; and the used antibacterial ingredient is the sulfadiazine silver which has excellent bactericidal performance and wide antimicrobial spectrum, the compound argentiferous antimicrobial dressings can provide favorable conditions for the wound, ensure rapid healing of the wound, and the production technology is simple, so that the compound argentiferous antimicrobial dressings have a broad application prospect.

The invention discloses compound nano-silver emulsifiable paste and a preparation method thereof. The compound nano-silver emulsifiable paste is O / W or W / O type emulsifiable paste prepared from nano-silver and zinc oxide as main drugs by certain processes. Nano-silver has strong antibacterial effects and a wide antimicrobial spectrum and causes drug resistance of bacteria difficultly. Zinc oxide has convergence and wound heal promotion effects. The compound nano-silver emulsifiable paste prepared from nano-silver and zinc oxide has anti-infection and wound heal promotion effects. The compound nano-silver emulsifiable paste has treatment advantages of moisture exposed burn ointment and sulfadiazine silver cream and avoids treatment defects and adverse reactions of moisture exposed burn ointment and sulfadiazine silver cream. The compound nano-silver emulsifiable paste can be used for anti-infection treatment on burns and scalds, infected wounds caused by physical mechanical damages, and chronic surface ulcers, and promotion of wound heal. The compound nano-silver emulsifiable paste can also be used for treatment on skin diseases such as sores, carbuncles, furuncles, erysipelas and tinea caused by bacteria, fungi and viruses.

The invention provides a nano-silver emulsifiable paste and its preparation method and relates to the field of medicines. The nano-silver emulsifiable paste is an O / W type emulsifiable paste or W / O type emulsifiable paste which is prepared by a certain preparation technology with nano-silver being used as a main drug. The nano-silver emulsifiable paste can be used for treating infection of infected wounds and body surface chronic ulcer (venous ulcer, pressure ulcer and the like) caused by burn and scald and physical and mechanical damage and for promoting healing of the wounds. The O / W type emulsifiable paste is similar to a moistening burn cream and can provide burn and scald wounds with a moistening environment which is beneficial to tissue regeneration. Simultaneously, due to specific high antibacterial activity and good wound heating promotion effect of the nano-silver, the nano-silver emulsifiable paste is better than the moistening burn cream; and in comparison with sulfadiazine silver and other external-use anti-infection drugs, the nano-silver emulsifiable paste is beneficial to wound healing, has no bacterial drug resistance and has high antibacterial activity.

The invention discloses a sulfanilamide medicament composition for a wound surface. The medicament composition contains sulfadiazine zinc, sulfadiazine silver and laurocapram, and can further contain preservative and medicinal calcium salt. The medicament composition is prepared into clinically acceptable formulations such as gel, mucilage, film coating agent and the like according to a conventional process by adding medicinal auxiliary materials. The medicament composition has strong antibacterial and bacteriostatic effects, obviously shortens the healing time of the wound surface, has good pain easing effect, is safe, effective and convenient to use; and the composition has stable anti-freezing property.

The invention relates to a flame-retardant and anti-corrosive coating for power equipment. The flame-retardant and anti-corrosive coating consists of the following components of melamine copolymer resin, styrene-maleic anhydride copolymer, nitrile rubber powder, polychlorinated biphenyl, ammonium polyphosphate, triphenyl phosphate, zinc hydroxystannate, diazolidinyl urea, propiconazole, calcium hypochlorite, sulfadiazine silver, limonene, sodium phosphate, crystalline graphite powder, diaminodiphenylmethane, calcium sulphate dehydrate, zinc fluoride, zirconite powder, aluminum phosphate powder, zinc sulfate, bowlder powder, glass fiber powder, transformer oil, propylene glycol methyl ether acetate, amyl propionate, aminopropyltriethoxysilane, amino silicone oil, amino acid, aminoethylpiperazine, and alkylolamide. The flame-retardant and anti-corrosive coating has the advantages that the flame-retardant, acid and alkali-resistant, mildew-proof and anti-bacterial properties are excellent; the product property is improved.

The invention discloses antibacterial medical drainage polyurethane foam and a preparation method thereof. The antibacterial medical drainage polyurethane foam is prepared from the following raw materials in parts by weight: 100 parts of polyether polyol, 1.2 to 3.5 parts of an organic silicon foam stabilizer, 1 to 15 parts of a foaming agent, 0.1 to 1 part of tannic acid, 0.1 to 0.6 part of imidazolidinyl urea, 0.5 to 6 parts of sulfadiazine silver, 1 to 10 parts of chitosan, 35 to 65 parts of toluene diisocyanate, 0.1 to 0.5 part of amine catalyst, 0.10 to 0.70 part of a zinc catalyst and 1 to 6 parts of water. According to the antibacterial polyurethane foam disclosed by the invention, various antibacterial agents such as chitosan, tannic acid and sulfadiazine silver are selected, oxygen active sites are provided for the polyurethane foam, so the polyurethane foam has an antibacterial property, meanwhile, the polyurethane foam has excellent biocompatibility, no teratogenic effect, no anaphylactic reaction and excellent anticoagulant performance; a toxicity test result show that the polyurethane foam meets medical requirements; and the te polyurethane foam has the advantages of excellent toughness and elasticity, good processability, various processing modes and the like.

The invention relates to an aluminum-alloy door and window protection coating material for a smart home. The protection coating material is prepared from 16-20 parts of acrylic acid, 18-22 parts of bronze powder, 14-18 parts of tribasic lead sulfate, 12-16 parts of alumina powder, 18-22 parts of polybutylene terephthalate, 14-18 parts of polyethylene wax, 12-16 parts of flax seed oil, 18-22 parts of dioctyl phthalate, 14-18 parts of barite powder, 12-16 parts of isothiazolinone, 18-22 parts of tributyl citrate, 14-18 parts of aluminium stearate, 14-18 parts of benzoic acid, 12-16 parts of vanillin, 18-22 parts of prochloraz, 14-18 parts of sulfadiazine silver, 12-16 parts of tetramethyl thiuram disulfide, 18-22 parts of nylon fibers, 14-18 parts of dicumyl peroxide, 12-16 parts of methyl vinyl silicone rubber, 18-22 parts of zirconia powder, 14-18 parts of cobalt aluminate powder and 12-16 parts of expanded perlite powder. The aluminum-alloy door and window protection coating material has excellent flame retarding, acid and alkali resistant, anti-mildew and antibacterial properties.

The invention discloses a polydopamine film as well as a preparation method and an application thereof. The polydopamine film is loaded with sulfadiazine silver. According to the preparation method, in-situ synthesis of sulfadiazine silver on the conventional polydopamine film is realized through microwave irradiation. In the method, the sulfadiazine does not need to be dissolved by the traditional ammonia water, so that the method has the following advantages: firstly, the corrosion effect of the ammonia water on the polydopamine film can be avoided; secondly, stimulation and corrosion of theammonia water to mucous membranes such as eyes and nasal cavities of a worker can be avoided; and thirdly, the environmental problem caused by pungent smell smoke volatilized by the high-concentration ammonia water can be avoided. In the method, a catalyst trifluoromethanesulfonic acid or trifluoromethanesulfonate is not used, so that the loading capacity of sulfadiazine silver can be improved, and the safety performance can be further improved.

The invention discloses an ink for a positioning pen special for radiotherapy for preventing wet skin and a preparation method thereof, and the ink for the positioning pen special for radiotherapy for preventing wet skin comprises the following components in parts by mass: 5-8 parts of pure essential oil, 5-10 parts of lemon stock solution, 1-2 parts of Indian henna powder, 0.5-1 part of vitamins, 3-5 parts of sea buckthron oil and 80-90 parts of American genipah juice. The sea buckthorn oil is adopted for preventing the wet skin, the effect is obviously better than that of gentian violet, kangfuxin, sea buckthorn flavone and sulfadiazine silver, and the wet skin can be effectively prevented. The prepared ink is high in coloring power and lasting in coloring, clear marking can be achieved only through one time, fading cannot occur in a short time, the acute LD 50 of NIH mice is larger than 5000 mg / kg, and the ink belongs to an actual non-toxic product and cannot cause harm to the human body in the using process.

The invention discloses a silver-containing hydrogel type alginate fiber and a preparation method thereof. The method comprises the following steps that (1) sulfadiazine sodium and sodium alginate are dissolved in water together to obtain a mixed solution, and the obtained mixed solution is vacuumized and defoamed to obtain a solution A; (2) a silver nitrate solution is added into the solution A, and is kept standing for reaction to obtain a mixed spinning solution containing silver sulfadiazine with antibacterial property; (3) the mixed spinning solution is subjected to wet spinning in a coagulating bath, calcium alginate nascent fibers are obtained, and the coagulating bath is a calcium chloride aqueous solution; (4) sodium alginate is dissolved in water to prepare a sodium alginate aqueous solution; (5) the calcium alginate nascent fiber is immersed into a sodium alginate aqueous solution, and hydrogel type alginate fiber is formed through reaction; (6) the fiber moisture is squeezed, and soaking with an ethanol water solution, and the moisture is squeezed again; and (7) the fiber is soaked in a sodium chloride aqueous solution, and and dried to constant weight to obtain a target product. The method can avoid the problem of fiber blackening caused by addition of silver ions.

The invention discloses sulfadiazine silver controlled-release gel which is prepared by the following method: (1) evenly mixing sulfadiazine silver and sodium alginate aqueous solution into a suspension in darkness, pouring the suspension onto a glass plate mold to make same naturally and smoothly flow, freezing and unfreezing at the room temperature in darkness; (2) adding calcium chloride to water-soluble chitosan solution, and fully mixing until the calcium chloride is dissolved to obtain the water-soluble chitosan-calcium chloride mixture; and (3) immersing the prepared product in step (1) in the water-soluble chitosan-calcium chloride mixture, holding, removing the glass plate mold and rinsing to obtain the sulfadiazine silver controlled-release gel. The sulfadiazine silver controlled-release gel of the invention has good biocompatibility and achieves the effects of stopping bleeding and helping healing; and the sulfadiazine silver controlled-release gel achieves good effect of moisture preservation and is favorable for healing the wound surface and easily applied and removed, thus relieving the pain of the sick and wounded caused by secondary wound.

The invention discloses compound nano-silver emulsifiable paste and a preparation method thereof. The compound nano-silver emulsifiable paste is O / W or W / O type emulsifiable paste prepared from nano-silver and zinc oxide as main drugs by certain processes. Nano-silver has strong antibacterial effects and a wide antimicrobial spectrum and causes drug resistance of bacteria difficultly. Zinc oxide has convergence and wound heal promotion effects. The compound nano-silver emulsifiable paste prepared from nano-silver and zinc oxide has anti-infection and wound heal promotion effects. The compound nano-silver emulsifiable paste has treatment advantages of moisture exposed burn ointment and sulfadiazine silver cream and avoids treatment defects and adverse reactions of moisture exposed burn ointment and sulfadiazine silver cream. The compound nano-silver emulsifiable paste can be used for anti-infection treatment on burns and scalds, infected wounds caused by physical mechanical damages, and chronic surface ulcers, and promotion of wound heal. The compound nano-silver emulsifiable paste can also be used for treatment on skin diseases such as sores, carbuncles, furuncles, erysipelas and tinea caused by bacteria, fungi and viruses.

The invention provides a method for synthesizing medicinal sulfadiazine silver. The method comprises the steps of allowing silver nitrate solution and sulfadiazine sodium solution which are fed and stirred simultaneously to react in a reaction tank, standing, draining, centrifugally drying and obtaining a sulfadiazine silver product, wherein the synthesis reaction temperature of silver nitrate and sulfadiazine sodium is 45 to 55 DEG C, and trifluoromethanesulfonic acid (salt) catalysts are used in the process of utilizing sulfadiazine powder and sodium hydroxide to prepare the sulfadiazine sodium.

The invention discloses a sulfadiazine silver cream and a preparation method thereof, and relates to the technical field of medicinal cream preparation. The cream is high in stability, not prone to discoloring and high in product quality. Meanwhile, the invention also provides a preparation method of the sulfadiazine silver cream, and the sulfadiazine silver cream prepared by the method is uniformin content, smooth and fine, moderate in consistency, good in spreading property and relatively fine in medicine granularity, and meets the standard requirements of pharmacopeia.