46 results about "Sulfadiazine Silver" patented technology

The invention discloses a nanometer antibiotic composite material of polymer / montmorillonite-soya bean lecithin-silvadene, which comprises the following parts: 100g polymer, 0.1-10g montmorillonite-soya bean lecithin-silvadene composition, 0-400g dispersing dielectric, 0-10g crosslinking agent and 0-1g accelerant, wherein the polymer is composed of raw rubber of silicon rubber, polyurethane or two copolymer or polyolefin material; the raw rubber of silicon rubber is selected from indoor-temperature silicon rubber, high-temperature silicon rubber, addition-typed silicon rubber; the polyolefin material can be PE, PVC, PP; the ion exchange content of montmorillonite is 70-120mmol / 100g.

The invention discloses sulfadiazine silver controlled-release gel which is prepared by the following method: (1) evenly mixing sulfadiazine silver and sodium alginate aqueous solution into a suspension in darkness, pouring the suspension onto a glass plate mold to make same naturally and smoothly flow, freezing and unfreezing at the room temperature in darkness; (2) adding calcium chloride to water-soluble chitosan solution, and fully mixing until the calcium chloride is dissolved to obtain the water-soluble chitosan-calcium chloride mixture; and (3) immersing the prepared product in step (1) in the water-soluble chitosan-calcium chloride mixture, holding, removing the glass plate mold and rinsing to obtain the sulfadiazine silver controlled-release gel. The sulfadiazine silver controlled-release gel of the invention has good biocompatibility and achieves the effects of stopping bleeding and helping healing; and the sulfadiazine silver controlled-release gel achieves good effect of moisture preservation and is favorable for healing the wound surface and easily applied and removed, thus relieving the pain of the sick and wounded caused by secondary wound.

The invention relates to the technical field of medicines, in particular to a cherokee rose leaf extract and application thereof in preparing medicine capable of curing burn and scald. By a rat wound healing test, a Pseudomonas aeruginosa infection mice in vivo protection test and an anti-inflammatory test, the healing action on burn and scald by the cherokee rose leaf extract is observed. Results show that the cherokee rose leaf extract has high healing rate to burn and scald wound surface, can obviously inhibit Pseudomonas aeruginosa infection, can obviously inhibit mice ear dwelling actionand has no obvious difference with positive sulphonamide sulfadiazine silver (SD-Ag), and thus the cherokee rose leaf extract can be used for preparing medicines capable of curing burn and scald. Thecherokee rose leaf extract has simple preparation method and low cost and provides a new medicine resource for curing burn and scald.

The invention discloses compound nano-silver emulsifiable paste and a preparation method thereof. The compound nano-silver emulsifiable paste is O / W or W / O type emulsifiable paste prepared from nano-silver and zinc oxide as main drugs by certain processes. Nano-silver has strong antibacterial effects and a wide antimicrobial spectrum and causes drug resistance of bacteria difficultly. Zinc oxide has convergence and wound heal promotion effects. The compound nano-silver emulsifiable paste prepared from nano-silver and zinc oxide has anti-infection and wound heal promotion effects. The compound nano-silver emulsifiable paste has treatment advantages of moisture exposed burn ointment and sulfadiazine silver cream and avoids treatment defects and adverse reactions of moisture exposed burn ointment and sulfadiazine silver cream. The compound nano-silver emulsifiable paste can be used for anti-infection treatment on burns and scalds, infected wounds caused by physical mechanical damages, and chronic surface ulcers, and promotion of wound heal. The compound nano-silver emulsifiable paste can also be used for treatment on skin diseases such as sores, carbuncles, furuncles, erysipelas and tinea caused by bacteria, fungi and viruses.

The invention provides a method for synthesizing medicinal sulfadiazine silver. The method comprises the steps of allowing silver nitrate solution and sulfadiazine sodium solution which are fed and stirred simultaneously to react in a reaction tank, standing, draining, centrifugally drying and obtaining a sulfadiazine silver product, wherein the synthesis reaction temperature of silver nitrate and sulfadiazine sodium is 45 to 55 DEG C, and trifluoromethanesulfonic acid (salt) catalysts are used in the process of utilizing sulfadiazine powder and sodium hydroxide to prepare the sulfadiazine sodium.