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Compound argentiferous antimicrobial dressings

A compound and composite fiber technology, applied in coatings, medical science, absorbent pads, etc., to achieve broad application prospects, simple production process, and good biocompatibility

Inactive Publication Date: 2013-02-13
WUXI ZHONGKE GUANGYUAN BIOMATERIALS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no antibacterial dressing prepared by combining polymers such as sodium alginate and chitosan

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Prepare the stent covering film with hemostatic and antibacterial function according to the following method:

[0018] (1) configure the sponge solution: the powder of sodium alginate and chitosan is dissolved in double distilled water at 50 degrees centigrade respectively, and the concentration is 2% (W / W). After fully dissolving for 5 hours, mix the two liquids with 9 : 1 ratio and stirred at room temperature for 30 minutes.

[0019] (2) Preparation of sponge: pour the mixed solution into a polystyrene petri dish, freeze overnight at minus 70°C, and freeze-dry at minus 50°C for 24 hours; then directly immerse the sponge in a mixture of acetone and water , volume ratio 9:1; at the same time, 50 mg of 1-ethyl (3-3-dimethylamino) carbodiimide salt (EDC) was added to the solution, and then shaken at room temperature for 24 hours.

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Abstract

The invention relates to compound argentiferous antimicrobial dressings which are characterized in that the antimicrobial dressings are formed by natural macromolecule materials and sulfadiazine silver; the natural macromolecule materials are used as main raw materials, composite fibre sponge body materials are produced by means of utilization of freeze drying technique, and the sulfadiazine silver is loaded on the sponge body to form the antimicrobial dressings; and by means of the utilization of the freeze drying technique and by means of spray coating, the sulfadiazine silver is loaded on the sponge body to form the antimicrobial dressings. The antimicrobial dressings are good in biological compatibility and favorable for wound healing and skin regeneration, and maintain a moist environment for a wound; and the used antibacterial ingredient is the sulfadiazine silver which has excellent bactericidal performance and wide antimicrobial spectrum, the compound argentiferous antimicrobial dressings can provide favorable conditions for the wound, ensure rapid healing of the wound, and the production technology is simple, so that the compound argentiferous antimicrobial dressings have a broad application prospect.

Description

Technical field: [0001] The invention relates to an antibacterial dressing, in particular to a silver-containing composite fiber antibacterial dressing with broad-spectrum antibacterial effect. Background technique: [0002] The skin is composed of epidermis, dermis and subcutaneous tissue. Its function is to protect internal tissues from external damage; perform metabolism, such as absorption, perspiration, secretion of sebum and excretion of waste; the skin can also regulate body temperature, feel pain, touch and pressure , temperature, cold and other stimuli, and have immune effects. The total area of ​​adult skin is about 1.5-2.0m2, and the thickness is between 0.5-4.0mm. Among the various injuries of the skin, traumatic bleeding and burns are more common. Damaged skin and tissues will cause a series of complex pathological and physiological changes in the whole body. These include water, electrolyte, and acid-base imbalances, and even shock, infection, and sepsis. A...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/22A61L15/44A61L15/28A61L15/32C08J7/06C08L5/04C08L89/00C08L3/02C08L5/10C08L1/02C08L5/08
Inventor 韩志超许杉杉
Owner WUXI ZHONGKE GUANGYUAN BIOMATERIALS
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