187 results about "Phenylethyl Alcohol" patented technology

The invention discloses total triterpene extract and total phenol extract extracted from Chinese herbal medicine glossy privet fruit and a preparation method thereof. The total triterpene extract mainly contains oleanolic acid, ursolic acid, acetyl oleanolic acid, indicant compound and other derivatives with acetyl oleanolic acid as the mother nucleus. The total phenol extract mainly contains hydroxyl mandelic, 3, 4-dihydroxy phenylethyl alcohol, salidroside and indicant compound and other derivatives with salidroside as the mother nucleus. The glossy privet fruit total triterpene extract and total phenol extract can be prepared by any method of solvent distillation, solvent extraction, deposition, macroporous resin absorption, supercritical fluid extraction, column chromatography and liquid-liquid countercurrent distribution chromatography, or any combination of these methods. The total percentage of various triterpenoids of the prepared glossy privet fruit total triterpene extract is 5 to 100 percent (w / w); wherein, the content of oleanolic acid and ursolic acid accounts for 5 to 100 percent (w / w) of the total triterpene. The total percentage of various phenols of the prepared glossy privet fruit total phenol extract is 5 to 100 percent (w / w); wherein, the content of salidroside accounts for 5 to 100 percent (w / w) of the total phenol.

The invention relates to a 2-phenylethanol-producing yeast strain, its culturing method and application. The Saccharomyces cerevisiae WHH6 strain provided in the invention is preserved on December 20, 2010 in the General microbiological center of China Committee for Culture Collection of Microorganisms. The preservation address is: Institute of Microbiology of Chinese Academy of Sciences, No.3, No.1 yard, Beichen West Road, Chaoyang District, Beijing. The spawn preservation number is CGMCC No.4491. The Saccharomyces cerevisiae WHH6 strain screened out by the invention has the characteristic of high 2-phenylethanol yield, which is detected to be able to reach 5.8564g / L. And the strain has high tolerance to 2-phenylethanol, thus being in favor of application of the strain in the industrial production of 2-phenylethanol.

The invention discloses a formula of tobacco flavoring essence with sweet essence. According to the formula, the tobacco flavoring essence consists of the following components in percentage by mass: 1.0 to 4.0 percent of ethyl maltol, 2.0 to 3.0 percent of plum extractum, 1.0 to 2.0 percent of phenethyl ethanol, 0.01 to 0.1 percent of damascenone, 0.1 to 0.5 percent of phenylacetic acid ethylester, 0.5 to 1.0 percent of methyl cyclopentenotone, 2.0 to 5.0 percent of red date extractum, 0.01 to 0.03 percent of linalool, 0.02 to 0.08 percent of 5-methylfurfural, 0.1 to 0.5 percent of benzoic acid, 0.05 to 0.15 percent of beta-irisone, 0.02 to 0.08 percent of 4-guaethol, 15 to 25 percent of glycerol, 45 to 55 percent of propylene glycol and 3 to 15 percent of purified water. By the formula, tobacco produces sweet fragrance, tobacco fragrance can be increased and taste of the tobacco can be adjusted, so that the taste of the tobacco is improved, the natural sweet fragrance of the tobacco is enhanced and dry, astringent and bitter mouthfeel of customers is improved and requirements of the customers are met.

The invention discloses a chiral tridentate PNN ligand and application of the same in asymmetric hydrogenation and similar reactions. The tridentate nitrogen phosphine ligand disclosed in the invention has been the first reported nitrogen phosphine ligand containing chiral oxazoline so far and has been successfully applied to high-efficiency and high-selectivity hydrogenation and similar reactions of ketone and imine salts. Compared with other ligand, the ligand provided by the invention is simpler in synthetic route, higher in yield and environment-friendlier; moreover, the metal complex of the ligand shows better selectivity and a higher turn-over number in asymmetric hydrogenation. An iridium complex of the chiral tridentate PNN ligand has successfully realized asymmetric reduction of beta-ketone ester into beta-alcohol ester (which is a raw material for synthesis of molecular drugs duloxetine and atomoxetine), asymmetric hydrogenation of alpha-hydroxyacetophenone into alpha-hydroxyphenylethyl alcohol and asymmetric hydrogenation of acetophenone into phenylethyl alcohol, which is of important significance to production of the medical industry.

The invention discloses a brewing method of rice aromatic liquor. The method is described as following: after being steamed and cooked, paddy is spread, cooled and inoculated in raw starter complex wine yeast. Then semisolid is fermented under a constant temperature of 38-41 DEG C, after which the rice aromatic liquor is made by blending the distilled fermentation broth. The brewing method of the invention adopts cooked paddy for fermentation, increases the rice aromatic flavour to the rice aromatic liquor. Compared with traditional rice fermentation method, the brewing method of the invention improves wine yield rate, prolongs fermentation period, and has more flavour substances (total acid, total ester, ethyl lactate, beta-phenylethyl alcohol) in liquor finished product in different extent than the falvour substances in traditional liquor finished product.

The invention discloses a linear polyethylene glycol fragrance slow-release cigarette filter rod and a production method thereof. A polyethylene glycol flavored line is arranged in the linear polyethylene glycol fragrance slow-release cigarette filter rod along the axis direction of the linear polyethylene glycol fragrance slow-release cigarette filter rod and phenylethyl alcohol flavor components are embedded in the linear polyethylene glycol fragrance slow-release cigarette filter rod with the polyethylene glycol flavored line as a carrier. The production method includes the following steps that polyethylene glycol is heated to 60 to 80 DEG C to be completely melted; the phenylethyl alcohol flavor components with the proportion of 5 weight percentage are added and uniformly stirred; liquid polyethylene glycol containing phenylethyl alcohol passes through a pore with a 0.5 mm pore diameter to form into trickles; the trickles directly flow on the surface of filter tows with the proportion of 40 mg per branch after opening of the filter tows; and the liquid polyethylene glycol can be cooled and solidified in a filter to form into the flavored line after the liquid polyethylene glycol passes through an opium pipe and the filter is solidification formed. According to the linear polyethylene glycol fragrance slow-release cigarette filter rod and the production method thereof, the problems that the release of the flavor components of favored line filters is non-uniform, the adsorbed quantity of the flavor components is small, the fragrance depositing time is short, the transfer efficiency is low and the like can be greatly solved.

The invention discloses escherichia coli gene engineering bacteria for four enzyme co-expression. The engineering bacteria is characterized by introducing an L-amino acid oxidase gene, an alpha-ketonic acid decarboxylase gene, an alcohol dehydrogenase gene, and an enzyme gene capable of reducing NAD(P) to NAD(P)H. The invention further discloses a construction method and application of recombinantescherichia coli. The engineering bacteria is applied to biological synthesis of phenylethyl alcohol compounds, has the characteristics of simple operation, low cost, high product synthetic efficiency, and high optical purity, and has bright industrial prospects.

The invention discloses flower fragrance aroma essence for tobacco, which is mixed by the following raw material components by weight: 0.2-0.3 part of phenylacetaldehyde, 1-2 parts of lavender oil, 0.6-0.8 part of benzyl acetate, 5-8 parts of fragrant perilla oil, 1-5 parts of magnolia essential oil, 1-5 parts of nerol, 2-5 parts of citronellol, 1-3 parts of phenylethyl alcohol, 0.05-0.2 part of sweet osmanthus extracts, 1-3 parts of dendranthema indicum ultrasonic extracts, 0.6-0.8 part of linalyl acetate, 1-5 parts of rhodinol, 2-3 parts of alpha-ionone, and 58.9-83.5 parts of 95% ethanol. The invention prevents pollen gas of the flower extracts by extraction of various flowers. The invention realizes effective compounding of single raw materials, which is a scientific and effective method. The flower fragrance aroma essence for tobacco is blended by raw materials with flower fragrance aroma, and a proper amount of the essence can be added directly into surface fragrance essence for tobacco. The essence effect is improved, and convenience for essence development is provided; the cost is low, and the usage is convenient.

The invention relates to a method for simultaneously preparing phenylethanoid glycoside, mannitol, oligosaccharide syrup and polysaccharide from broomrape, which comprises the following steps: extracting monosaccharide, oligosaccharide and phenylethanoid glycoside in broomrape by using an ethanol water solution, separating the phenylethanoid glycoside and saccharide with a macroporous adsorbent resin column, carrying out concentration and drying on the phenylethanoid glycoside solution obtained by elution to obtain the product, concentrating the saccharide under reduced pressure, crystallizing at normal temperature, separating the oligosaccharide and mannitol, recrystallizing the mannitol to obtain the high-purity mannitol, centrifugating the clear solution to obtain the oligosaccharide syrup, extracting the polysaccharide from residues by using pure water, and carrying out alcohol precipitation to collect the polysaccharide. The method enhances the comprehensive utilization ratio of the broomrape resources, simplifies the production technique, develops the phenylethanoid glycoside, mannitol, oligosaccharide syrup and polysaccharide products simultaneously, increases the economic added value of the broomrape product, and has favorable industrial production and market development prospects.

The invention provides silica-bonded dual-chiral active central chromatography filler, a preparation method and applications thereof, belonging to the field of column filling. The preparation method comprises the following steps of: (1) activation of silica gel; (2) protection of microcrystalline cellulose 6-hydroxyl group; (3) carbonyl acyl chlorination; (4) derivative process of microcrystalline cellulose 2, 3-hydroxyl group and protection removal of 6-hydroxyl group; and (5) obtaining bonded chiral fixed phase by silica-bonded 2, 3-bonded 6-protection removal microcrystalline cellulose reaction and passivation of activated silica gel unreacted silanol group. The dual-chiral bonded chiral fixed phase is used for separating asymmetric synthesized chiral compounds, and n-hexane-isopropanol is used as flowing phase so as to separate the phenylethyl alcohol and ethanethioic acid, thus obtaining chromatograms. The filler, the preparation method and the application have high column efficiency, short separation time, and good separation effect on chiral compounds. The filling material generates no swelling even when in solvent, has good permeability performance and low column pressure; under the conditions of 100 percent n-hexane, flowing speed of 1ml / min and the chromatographic column of 150 multiplied by 4.6mm i.d, the column pressure is only 3.3MPa.

What is described herein is an antiperspirant composition including an active antiperspirant ingredient, and a phenylethyl, benzyl or substituted benzyl ester as additive therein, which is an aryl carboxylic ester of 2-phenylethyl alcohol, 1-phenylethyl alcohol or benzyl alcohol, which leaves a reduced visible white chalky residue on the skin of the user.

The invention relates to a composite decarburization solution for capturing carbon dioxide in mixed gas, belonging to the technical field of carbon dioxide gas capture. It relates to a composite decarburization solution, which is composed of solvent benzyl alcohol, phenyl alcohol, N-methylpyrrolidone or a mixture thereof, main absorption component MEA, auxiliary absorption components EDA, DETA and TETA, active components PZ and 2, 3-butanedione, the corrosion inhibitor is sodium chromate, and the antioxidant is sodium metavanadate and copper carbonate. Since the composite decarburization liquid uses a mixed solvent, it not only improves the absorption capacity, purification degree and desorption rate of carbon dioxide, expands the reaction temperature range, but also reduces the volume of the desorption tower, greatly reduces regeneration energy consumption, and reduces equipment investment and operating costs. The invention is mainly used for capturing carbon dioxide in various chemical reaction tail gas, ore decomposition gas, combustion flue gas, natural gas, city gas and biogas, and has broad application prospects.

Belonging to the technical field of industrial microbiology, the invention discloses a saccharomyces cerevisiae and application thereof in food fermentation. The saccharomyces cerevisiae strain 11-1 is preserved in China Center for Type Culture Collection on September 11, 2017 at Wuhan University, Wuhan, China, and the preservation number is CCTCC NO:M 2017488. Sense mutation occurs to the key gene pha2 in the path of synthesizing beta-phenylethyl alcohol from the strain, and the catalytic ability of mutated prephenate dehydratase PHA2P is strengthened by 22%. The invention also finds that thesaccharomyces cerevisiae pha2p suffers from the feedback inhibition of L-phenylalanine, when the strain is used for fermenting yellow rice wine, the alcoholic strength can reach 13 degrees, and the yield of beta-phenylethyl alcohol can reach 120mg / L.

What is described herein is an antiperspirant composition including an active antiperspirant ingredient, and a phenylethyl, benzyl or substituted benzyl ester as additive therein, which is an aryl carboxylic ester of 2-phenylethyl alcohol, 1-phenylethyl alcohol or benzyl alcohol, which leaves a reduced visible white chalky residue on the skin of the user.

The invention discloses a biosynthesis method of caffeic acid phenethylester by means of transesterification. The caffeic acid phenethylester is prepared by reacting caffeic acid alkyl ester with phenylethyl alcohol in an ionic liquid by taking the ionic liquid as a reaction medium and lipase as a catalyst, the caffeic acid alkyl ester and the phenylethyl alcohol are added at a molar ratio of 1:(1-40), the lipase is added according to the molar ratio of the caffeic acid alkyl ester to the lipase of 1:(1-40), the ionic liquid is added according to the volume ratio of the phenylethyl alcohol to the ionic liquid of 1:(5-50), reaction temperature is 40-90 DEG C, oscillation rotation speed is 120-300 rpm (revolutions per minute), and reaction time is 10-72 hours. The transesterification method provided by the invention takes the ionic liquid as the reaction medium, is capable of increasing the solubility of a substrate with a product, improving the catalytic activity and reaction efficiency of an enzyme and shortening the reaction time, is simple in operation, mild in conditions, high in product yield, and environmentally-friendly, and has good application prospect.

The invention discloses a method for directly detecting tea glucoside combined state aroma precursor substances. According to the invention, fresh tea leaves, a tea product being processed or a tea finished product are used as a to-be-measured sample, the method comprises the following steps: 1) extracting a glucoside combined state aroma precursor from the to-be-measured sample, 2) performing a UPLC-MS / MS analysis on the glucoside combined state aroma precursor in an extract, and 3) calculating the content of the tea glucoside combined state aroma precursor substances: by taking a 4-nitrophenyl-beta-D-glucoside internal standard as a reference, obtaining 9 glucoside combined state aroma precursor substances of benzyl alcohol primrose gluocoside, methyl salicylate primrose glucoside, phenylethyl alcohol primrose glucoside, cis 3-hexenol primrose glucoside, linalool oxide I primrose glucoside, linalool oxide II primrose glucoside, linalool oxide primrose glucoside III, linalool primroseglucoside, and geraniol primrose glucoside. The method has high detection efficiency on the glucoside combined state aroma precursor substances.

The invention relates to a method for preparing a camellia sinensis extract through dynamic / static combined subcritical CO2 extraction, which belongs to the field of processing of natural products. The method provided in the invention comprises the procedures of selective picking of camellia sinensis, dehydration, fragmentation, selection of an entrainer, dynamic / static combined subcritical CO2extraction, fractionation, condensation, etc. According to the invention, extraction conditions for the method are mild; the method enables main aroma components in camellia sinensis like acetophenone, leaf alcohol, phenylethyl alcohol and alpha-phenylethyl alcohol to be effectively retained, polar and non-polar ingredients in aroma components of camellia sinensis to be highly effectively extracted and high extraction efficiency to be obtained; the obtained camellia sinensis extract can be directly used as a product and can also be further separated and purified for preparation of high-grade essence or champignon products, having a promising market prospect and development value.

The invention discloses a formula of tobacco flavoring essence with sweet fragrance. According to the formula, the tobacco flavoring essence consists of the following components in percentage by mass: 1.0 to 4.0 percent of ethyl maltol, 2.0 to 3.0 percent of plum extractum, 1.0 to 2.0 percent of phenethyl ethanol, 0.01 to 0.1 percent of damascenone, 0.1 to 0.5 percent of phenylacetic acid ethyl ester, 0.5 to 1.0 percent of methyl cyclopentenotone, 2.0 to 5.0 percent of red date extractum, 0.01 to 0.03 percent of linalool, 0.02 to 0.08 percent of 5-methyl furfural, 0.1 to 0.5 percent of benzoic acid, 0.05 to 0.15 percent of beta-irisone, 0.02 to 0.08 percent of 4-guaethol, 15 to 25 percent of glycerol, 45 to 55 percent of propylene glycol and 8 to 15 percent of purified water. By the formula, tobacco produces sweet fragrance, tobacco fragrance can be increased and taste of the tobacco can be adjusted, so that the taste of the tobacco is improved, the natural sweet fragrance of the tobacco is enhanced, dry, astringent and bitter mouthfeel of customers is improved and requirements of the customers are met.

The invention discloses a method for preparing 2-phenylethyl alcohol, which comprises the following steps: adding active saccharomyces cerevisiae in a biotransformation medium, taking L-phenylalanine as a substrate and glucose as a carbon source, adding an anti-oxidant, and fermenting under aerobic condition to obtain 2-phenylethyl alcohol. According to the invention, L-phenylalanine is taken as the substrate, glucose is taken as carbon source, under an alternative oxidation degraded system of glucose and ethanol, the anti-oxidant with certain concentration is added, and perfume 2-phenylethyl alcohol can be obtained through batch fermentation. The method increases the synthesis rate of products 2-phenylethyl alcohol, shortens biotransformation period; employs a method for disposable addition of the anti-oxidant to reduce the content of impurities such as butanols, isobutyric acid, butyric acid and isovaleric acid during the biotransformation process, and increases the 2-phenylethyl alcohol fragrance quality.

The invention discloses a biological culture method for producing 2-phenylethyl alcohol with high yield from saccharomyces cerevisiae. An optimized YEPD culture medium is inoculated with saccharomycescerevisiae obtained by separation from a brewery, slant culture, solid plate culture, liquid culture, strain amplification culture and fermentation culture are performed in sequence, then L-phenylalanine is converted and fermented, and 2-phenylethyl alcohol is produced. The saccharomyces cerevisiae strain is subjected to optimized culture, and the conversion ratio and yield of 2-phenylethyl alcohol produced from L-phenylalanine by fermentation are increased.

The invention relates to a method for preparing ropinirole hydrochloride, comprising the followings in turn: (1) beta-phenylethyl alcohol reacts with paraformaldehyde to produce isochroman; (2) the product obtained in step (1) reacts with bromide to produce 2-bromoethyl benzaldehyde; (3) the product obtained in step (2) reacts with nitromethane to produce 2-bromoethyl nitrostyrolene; (4) the product obtained in step (3) reacts with acetyl chloride to produce 4-bromoethyl-3-chloride-1, 3-dihydro-2H-indole-2-ketone; (5) 4-bromoethyl-1, 3- dihydro-2H-indole-2-ketone is obtained after catalytic hydrogenation of the product obtained in step (4); (6) 4-ethoxyl-1, 3-dihydro-2H-indole-2-ketone is obtained after acetylation and hydrolysis of the product obtained in step (5); (7) the product obtained in step (6) reacts with toluene sulfonic acid to produce toluene sulfonic acid-2-(2-oxygen-1, 3-dihydro-4-indole) ethyl ester; (8) the product obtained in step (7) and di-n-propylamine undergo reflux reaction in water and pH value is regulated by hydrochloric acid to 1-2 to obtain the ropinirole hydrochloride. In the method, the raw materials are easily acquired; the target products enjoy high selectivity and yield, thus being suitable for industrial production.

The invention provides a salt-tolerant rhodotorula mucilaginosa strain with high yield of phenylethanol and application thereof. The strain was deposited in the China General Microbiological Culture Collection Center on November 26, 2019 under a deposit number of CGMCC No. 19008. The strain has characteristics of salt tolerance, better growth stability, and producing strong sauce and mellow flavor, significantly increases content of active ingredients in volatile substances such as phenylethyl alcohol, furanone, maltol, 2,6-dimethylpyrazine, etc., and can be used for fermentation of high-saltdilute soy sauce to improve the flavor and quality of soy sauce products.

The invention discloses an aroma-producing yeast YG-4, a screening method thereof and a method for preparing flavor used for cigarette. A preservation number is CGMCC NO. 17223. The fragrant yeast YG-4 is used for tobacco aroma. The screening method of the aroma-producing yeast YG-4 comprises the following steps: by enriching and separating the fruit epidermis strains, several single colonies canbe obtained, the obtained single colonies are separately activated and cultured, then transplanted into a seed culture medium for fermentation, and a strain of aroma-producing yeast YG-4 which can impart aroma and sweetness to the fermentation liquid and is distinguished from the control is screened by a sensory olfactory comparison method. Compared with the prior art, the present invention provides the aroma-producing yeast YG-4, which can ferment the seed culture medium containing tobacco powder, and can generate 32 kinds substances of aromas such as esters, carbonyls, acids, hydrocarbons and alcohols contributing to aroma, among them, the content of phenylethyl alcohol is large, the fragrance contribution is alrge, and the characteristics of the tobacco powder as a scent raw material are utilized. The application of the tobacco powder to the cigarette is easy to coordinate with a tobacco product, and the smoking quality of the cigarette is improved.

The invention discloses an Armeniaca vulgaris fermented extract and a preparation method and application thereof. The Armeniaca vulgaris fermented extract is prepared from Armeniaca vulgaris, which serves as a raw material, through fermenting with Lodderomyces elongisporus and extracting aroma components from a fermented solution. The Lodderomyces elongisporus is collected in the China General Microbiological Culture Collection Center (CGMCC); the collection number is CGMCC No. 6645; the collection date is October 08, 2012. The Armeniaca vulgaris fermented extract contains a variety of aroma substances, such as phenylethyl alcohol, capronaldehyde, benzaldehyde, ethyl acetate, 1-butanol and the like. Shown by results of flavored smoking assessment tests, the product can be harmonized with cigarette flavors, can obviously promote the cigarette flavors, make smoke gas delicate and mellow, lower irritation, conceal impurity gases and improve the smoking flavor of cigarettes, and can generate a fresh and special aroma.

The invention discloses a method for adsorbing phenylethyl alcohol. The method comprises the following step: mixing adsorbent and a fermentation liquid, wherein 2-phenylethyl alcohol in the fermentation liquid is adsorbed and enriched by the adsorbent; the adsorbent is polymer coated macroporous SiO2; and the concentration of the 2-phenylethyl alcohol in the fermentation liquid is 400-600 mg / kg. According to the method, the 2-phenylethyl alcohol can be adsorbed and enriched from the fermentation liquid; and the advantages of high selectivity, simple operation and high separation efficiency are achieved.

Directed at the problem that the fragrance of blended flavoring rose essence is greatly different from the fragrance of natural roses, the invention provides a flavoring rose essence for daily chemicals, belonging to the field of essence. The flavoring rose essence comprises the following components by mass: 45 to 55 parts of phenylethyl alcohol, 5 to 15 parts of citronellol, 1 to 10 parts of nerol, 1 to 10 parts of geraniol, 1 to 10 parts of rhodinol, 1 to 10 parts of ambrotone, 5 to 15 parts of galaxolide, 0.1 to 1 part of delta damascene, 0.01 to 0.1 part of rose oxide, 0.5 to 1.5 parts ofrose geranium oil, 0.1 to 1 part of damascenone and 10 to 20 parts of dipropylene glycol. By controlling the proportion of each component during preparation of the flavoring rose essence for daily chemicals, the aroma intensity of the flavoring rose essence for daily chemicals can be increased, the aroma given off by the flavoring rose essence for daily chemicals is closer to the natural aroma ofroses and is purer and richer, and thus, desired aroma can be generated by adding only a small amount of the flavoring rose essence into daily chemicals.

Provided is a perfume composition for expressing the fragrance of silk tree flower. The perfume composition includes the fragrance components of silk tree flower, linalool, cis-linalool oxide (furanoid), cis-linalool oxide (pyranoid) and 2-phenylethyl alcohol, and an artificially synthesized material, 3-methylbutanal oxime, and is capable of expressing the characteristic fragrance of silk tree flower and of providing improved preference of fragrance.