The invention discloses a preparation method of 4-benzyloxy phenyl ethyl n-decanoate, which comprises the following steps: A, adding
methanol, p-hydroxyphenethyl
alcohol and equivalent
benzyl chloride into a clean three-neck flask, uniformly stirring and mixing, then adding
sodium hydroxide solid in three batches, heating to
reflux after each time of addition, and reacting for 0.5 hour, so as to obtain 4-benzyloxy phenyl ethyl n-decanoate; b, after the reaction is finished, directly distilling out the
solvent, then after the
solvent is completely distilled, directly dropwise adding n-decanoyl
chloride with the same equivalent amount, and controlling the temperature to be lower than 20 DEG C, C, after the reaction is finished, adding a large amount of water, separating out a large amount of product at the moment, uniformly stirring, and centrifuging to obtain a crude product; and D, adding
ethanol into the crude product, heating and dissolving, cooling and separating out, and centrifuging again to obtain a refined product 4-benzyloxy phenyl ethyl n-decanoate. In the reaction stage, the usage amount of solvents and reagents is reduced, no acid-binding agent is used, and therefore
pollution to the environment is reduced, no by-product exists in the reaction process, and the production process is more
environmentally friendly.