Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

88 results about "Nano complex" patented technology

Preparation method and application of multifunctional membrane-controlled targeting nano-carrier integrating tracing and targeted drug delivery effects

The invention belongs to the technical fields of preparation and applications of nano-carriers, and in particular discloses a preparation method and an application of a multifunctional membrane-controlled targeting nano-carrier integrating tracing and targeted drug delivery effects. With nano mesoporous silica (MSN) as a drug 'warehouse', a positively charged high molecular material and a negatively charged high molecular material as preparation materials of a gating membrane, and adriamycin (DOX), cis-platinum, imatinib, taxol and the like as model anti-cancer drugs, research contents mainlyinclude optimization and improvement of natural materials, construction and process optimization of the gating membrane, structural characterization of a nano complex, drug release kinetic characteristics of drug molecules under the control of the gating membrane, and the like. Meanwhile, in the combination with the tracing imaging function of a fluorescent quantum dot, drug delivery behaviors andanti-tumor effectiveness of the membrane-controlled nano drug delivery system undergo preliminary evaluation through in-vitro experiments. Based upon research results, references are provided for thedesign and preparation of the novel membrane-controlled nano drug delivery system.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Novel mesoporous silicon sphere co-loaded medicine nano-complex and preparation method thereof

The invention discloses a novel mesoporous silicon sphere co-loaded medicine nano-complex and a preparation method thereof. The novel mesoporous silicon sphere co-loaded medicine nano-complex is Ce6@MMSN / DOX / Ko143@PAsp-b-PEG-FA; the preparation method comprises the following steps: selecting TEOS (Tetraethyl Orthosilicate) as a silicon source, CTAB (Cetyltrimethyl Ammonium Bromide) as a template agent and n-hexane as a pore expanding agent and synthesizing mesoporous silicon dioxide nanoparticles with a double-pore-channel core-shell structure; carrying out amination modification on the mesoporous silicon dioxide nanoparticles; synthesizing Fe3O4 nanoparticles by adopting an LSS (Liquid-Solid-Solution) phase transfer method and ligand exchange reaction; modifying and embedding superparamagnetic iron oxide nanoparticles on the surface of aminated MSN through nucleophilic substitution, so as to construct magnetic mesoporous silicon dioxide nanoparticles; taking DCC (Dicyclollexyl Carbodiimide) as a condensation agent and covalently binding a photosensitizer Ce6 through amidation; meanwhile, loading a BCRP (Breast Cancer Resistance Protein) inhibitor Ko143; then crossly linking a copolymer FA-PEG-b-PAsp; finally, loading an anti-tumor medicine DOX.
Owner:SECOND AFFILIATED HOSPITAL SECOND MILITARY MEDICAL UNIV

Method for simple and rapid preparation of hydrogel bilayer film with high adhesion acting force

The invention relates to a method for simple and rapid preparation of a hydrogel bilayer film with high adhesion acting force, and belongs to the field of functional polymer materials. According to the method, nano aluminum hydroxide sol, nano zirconium hydroxide sol, nano clay and the like are used as crosslinkers, acrylic acid, N,N-dimethacrylamide, acrylamide, N-isopropyl acrylamide and the like are used as monomers, and in-situ free radical polymerization is used for preparing various nano complex hydrogels; based on high-strength hydrogels, a bridged polymer is prepared by activation reaction of chitosan, sodium alginate and other macromolecules with carboxyl of EDC / NHS, and the bridged polymer is bonded by self or with other hydrogels to prepare the hydrogel bilayer film with high adhesion acting force in a wet environment; the bilayer film has extremely strong adhesion acting force, simple preparation method and easy operation in preparation process, greatly expands the application of the hydrogels, and has strong application potential in intelligent bionic drive, flexible sensing parts, biomedical materials and other fields.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY

SiC-ZrC-ZrB2 nano complex phase ceramic modified C/C composite material and preparation method thereof

The invention relates to a SiC-ZrC-ZrB2 nano complex phase ceramic modified C/C composite material and a preparation method thereof. A technical scheme adopted by the invention is that the preparation method of the SiC-ZrC-ZrB2 nano complex phase ceramic modified C/C composite material comprises the following steps: mixing 1-5wt% of organic boron, 5-10wt% of organic silicon, 10-20wt% of a ZrC precusor and 65-84wt% of an asphalt methylbenzene soluble component, adding a solvent to dissolve the mixture, reacting the obtained solution for 1-4 hours at 300-450 DEG C to obtain boron-silicon-zirconium-doped asphalt; dipping a carbon fiber prefabricated body with the boron-silicon-zirconium-doped asphalt, and then carrying out pyrolysis treatment to obtain a SiC-ZrC-ZrB2 nano complex phase ceramic modified C/C perform body; and repeatedly dipping and carrying out pyrolysis treatment on the SiC-ZrC-ZrB2 nano complex phase ceramic modified C/C perform body until the density is 1.9-2.5g/cm<3> to obtain the SiC-ZrC-ZrB2 nano complex phase ceramic modified C/C composite material. The composite material prepared by the preparation method has good mechanical performance, self-healing antioxidant ability and superhigh temperature ablation resistance within a wider temperature range.
Owner:WUHAN UNIV OF SCI & TECH

Nano carrier prepared from marine sulfated polysaccharide, nano complex and application of nano carrier

The invention discloses a nano carrier prepared from marine sulfated polysaccharide, a nano complex, and an application of the safe and nontoxic nano carrier with specific activity of the marine sulfated polysaccharide. According to the technique, the nano carrier is prepared from marine sulfated polysaccharide with certain biological activity as an edible and safe water-soluble biological macromolecular material by using intermolecular crosslinking and compounding of the marine sulfated polysaccharide and chitosan and derivatives of the chitosan; a hydrophobic microdomain formed by convolving between polysaccharide molecules is beneficial to adsorption and aggregation of fat-soluble active substances; entrapment and dispersion of a water-soluble nano carrier on the fat-soluble active substances are achieved; and the nano complex with good biological activity is formed. The prepared nano complex is beneficial to transportation and absorption of the active substances in vivo; and the bioavailability of the active substances is improved.
Owner:OCEAN UNIV OF CHINA

Nano-gold/manganese dioxide/graphene-carbon nanotube three-dimensional structural nano complex and hydrogen peroxide sensor prepared by using complex

The invention relates to a preparation method for a nanogold / manganese dioxide / graphene-carbon nanotube three-dimensional structural nano complex. The method specifically comprises the following steps: firstly carbon nanotubes are oxidized by a strong acid, and graphene oxide is stripped from the surfaces of the carbon nanotubes in the oxidation process, so that a graphene oxide-carbon nanotube three-dimensional carbon structure is formed; then KMnO4 is added to make manganese dioxide deposited on the surface of the carbon material, and the graphene oxide can be reduced to graphene through high-temperature heating; and manganese dioxide / graphene-carbon nanotubes are subjected to amination treatment, negatively-charged colloidal gold nanoparticles are immobilized on the surfaces of the aminated carbon nanotubes by utilizing electrostatic interaction, and therefore the complex is obtained. The preparation method provided by the invention is simple, and sandwich design of the manganese dioxide solves the problems of conductivity and stability of a manganese dioxide material and expands the application range of the manganese dioxide material; and a sensor prepared by using the complexrealizes rapid, sensitive and high-selectivity detection on hydrogen peroxide, and has potential application prospects.
Owner:ANYANG NORMAL UNIV

Preparation method of novel liquid-state nano complex flocculant

The invention belongs to the technical field of sewage treatment and particularly relates to a preparation method of a novel liquid-state nano complex flocculant. The preparation method comprises thefollowing steps: step 1, taking waste liquid containing hydrochloric acid, corroded aluminum and oxidized ferric, discharged in production processes, as raw materials, and performing stirring treatment for reacting to generate an aluminum chloride and ferric chloride mixture solution; step 2: adding the aluminum chloride and ferric chloride mixture solution generated in the reaction to a sodium hydroxide solution, adjusting the solution to a certain pH value, and standing the solution for a period of time to obtain a polymeric aluminum ferric chloride (PAFC) solution; and step 3, adding the obtained PAFC solution to an organic cation polymer product to generate a nano flocculant. The nano complex flocculant prepared by the preparation method provided by the invention has the beneficial effects that the nano complex flocculant belongs to an efficient complex variety, and pesticide wastes are used as raw materials, so that waste utilization is realized, ecological environment protectionis realized, and green cyclic development of agriculture is promoted; and compared with a traditional solid-state product, the nano complex flocculant has the advantages of high reaction speed, full reaction, uniform concentration and greatly improved treatment efficiency.
Owner:渤海今日(天津)科技有限公司

Fe@C@g-C3N4 nanometer composite and preparation method and application thereof

The invention discloses a Fe@C@g-C3N4 nanometer composite and a preparation method and application thereof, and belongs to the technical field of preparation of nanometer materials. A microscope structure of the nanometer composite material is a Fe@C core shell structure nanocapsule embedded in a g-C3N4 nanometer piece. Iron powder and melamine powder are pressed to a block as an anode target material according to a certain atomic percentage by a plasma arc discharge method; graphite serves as a cathode material; argon and methane serve as working gas; a certain distance is kept between a cathode graphite electrode and an anode iron-melamine powder block; and the arc discharge is performed between an anode and a cathode to obtain the Fe@C@g-C3N4 nanometer composite. A wave absorbing material prepared by the nanometer composite is excellent in microwave absorbing performance in 2-18 GHz range. The Fe@C@g-C3N4 nanometer composite is simple in preparation process, free of after-treatment procedures, low in cost and easy to realize industrial production.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products