144 results about "Hydracrylic acid" patented technology

The invention relates to a method for preparing monohydric alcohol or dihydric alcohol through organic acid hydrogenation. According to the method, any one of acetic acid, propionic acid, valeric acid, stearic acid, oleic acid, palmitic acid, levulinic acid, lactic acid, succinic acid, 3-hydracrylic acid and other organic acids is taken as a reactant, and an A-B/X supported catalyst is adopted, wherein the component A is any one or more than two from Ir, Pt, Pd, Rh and Ru, the assistant B is any one or more than two from Mo, Re and W, the carrier X is any one in SiO2, activated carbon, titanium oxide, zirconium oxide, SiO2-Al2O3 (the mass content of Al2O3 accounts for 17 percent) and molecular sieves, the mass load amount of A in the catalyst is 0.5-10 percent, the molar ratio of the assistant B to A is 0.01-1.0, the reaction pressure is 2-20 MPa, and the reaction temperature is 40-180 DEG C. The catalyst has the characteristics of mild reaction conditions, high reaction activity and good selectivity, and a novel effective way for preparing monohydric alcohol or dihydric alcohol from biomass is provided.

The invention relates to an asymmetric synthesis method of (+)-tanshinol, which comprises the following steps: carrying out Knoevenagel condensation on the raw material heliotropin, hydrolyzing for ring opening to obtain beta-(3,4-3,4-methylenedioxyphenyl)pyruvic acid, carrying out key asymmetric reduction reaction to obtain R-beta-(3,4-dibenzyloxyphenyl)-alpha-hydracrylic acid, and finally, deprotecting to obtain the (+)-tanshinol. The method has the advantages of accessible raw material and high optical purity of the product, is simple to operate, and can implement large-scale preparation.

The invention discloses an amino acid anti-aging cream which comprises three components A, B and C in parts by weight, the component A comprises the following materials in parts by weight: 18-25 parts of ozocerite, 4-7 parts of octadecanoic acid, 4-6 parts of stearyl alcohol, 2-5 parts of sp-60, 2-4 parts of Tween-60, 1-3 parts of hydrogenated lanolin, 1-2 parts of beewax and 0.1-0.3 part of propyl p-hydroxybenzoate; the component B comprises the following materials of 50-60 parts of distilled water, 3-8 parts of propylene glycol, 3-5 parts of cysteine, 1-3 parts of gamma-amino-beta-hydracrylic acid and 0.1-0.3 part of methyl parahydroxybenzoats; and the component C comprises the following material of 0.5-1 part of essence.

The invention discloses a recombinant strain for producing a 3-hydracrylic acid homopolymer and/or a 3-hydracrylic acid copolymer and an application thereof. The construction method of the recombinant strain comprises the following steps: leading 1,3-Propanediol dehydrogenase coded genes, aldehyde dehydrogenase coded genes, 3-hydracrylic acid coenzyme A ligase coded genes and PHA (Polyhydroxyalkanoates) polymerase coded genes into a starting strain to obtain the recombinant strain. The experiments in the invention prove that the engineering bacteria can efficiently express 3-hydracrylic acid coenzyme A ligase coded genes and PHA polymerase coded genes and enable the 3-hydracrylic acid to be finally polymerized into 3-hydracrylic acid homopolymer (P(3HP)) from the 3-hydracrylic acid coenzyme A. Minitype fermentation tank experiments show that the engineering bacteria provided by the invention can have a maximum P (3HP) output of 8.9g/L after being fermented in a 6L fermentation tank and the P (3HP) can account for a maximum 91.5% of cell dry weight. In addition, the recombinant strain provided by the invention has the advantages of simple production process, low costs and broad application prospects.

The invention relates to the technical field of catalysts, in particular to a catalyst for hydrogenating 3-hydroxypropionate to prepare 1,3-propanediol and a preparation method thereof. The catalyst of the present invention is composed of CuO, ZnO, P and SiO2 four components, and the weight percentage of each component is CuO 25%~60%, ZnO 1%~30%, P 0.01%~10%, SiO2 30%~60% %, the total amount of the four components satisfies 100%. The preparation method of the catalyst is to first complex the copper salt and the ammonium salt and then blend them with a salt solution containing a certain amount of Cu and Zn, then add ammonium hypophosphite and silica sol in turn, and undergo aging, filtration, drying, molding, and high-temperature roasting. The obtained catalyst can be used to hydrogenate 3-hydroxy propionate to prepare 1,3-propanediol after being reduced in a reactor. The catalyst preparation method of the invention is simple and convenient, has long service life, good stability and high selectivity of 1,3-propanediol.

The invention discloses a construction method of a metabolic engineering escherichia coli strain for producing hydracrylic acid from acetic acid. Escherichia coli reformed by metabolic engineering isutilized for producing hydracrylic acid by fermenting acetic acid; and construction ways are as follows: constructing a metabolic way for producing hydracrylic acid from acetyl CoA, and/or over-expressing relevant genes of an acetic acid intake way so as to increase the transmission rate of acetic acid, and/or blocking or decreasing TCA circle so as to increase metabolic flow of acetyl CoA flowingtowards a target metabolite, and/or reducing decarboxylic reaction between malic acid or oxaloacetic acid so as to delete a byproduct generation way, and/or deleting key genes in an alcohol production way so as to regulate metabolic flow of an acetyl CoA node and/or regulating intracellular oxidation reduction balance through coenzyme engineering. According to the construction method, a production way for exogenously expressing hydracrylic acid is constructed, the metabolic ways, the adjustment and control are analyzed, and escherichia coli is reformed by virtue of a metabolic engineering measure, so that the prepared strain can be utilized for producing hydracrylic acid in a culture medium taking acetic acid as a carbon source.

The invention relates to synthesis method for leadless pure tin electroplating additive. Wherein, mixing lauryl phenol polyoxydivinyl ether, polyoxyethylene aniline ether, N, N-diethylm toluidine, hydracrylic acid, acetylglycine acid, naphthalene sulfonic acids, polyoxyethylene polyoxyprophylene propylene, and hydroquinone, and deionized water evenly by turns on given physical conditions; adjusting the constituents to eliminate compressive stress, control crystal process, and form perfect, normal crystallization structure; controlling particle size, thickness of plating layer and tin expansibility to solve generation problem of tin whisker. This invention is also easy to maintenance and needs low consumption.

The invention relates to a transformation microbe containing a recombinant vector, wherein the recombinant vector contains protein expressed by a nucleotide sequence shown by a gene code SEQ ID NO.1. A method for preparing the transformation microbe comprises introducing the nucleotide sequence shown by the gene code SEQ ID NO.1 into a host. The transformation microbe containing the recombinant vector is applied to generating 3-hydracrylic acid. A plasmid has high stability in a host strain, and is quite suitable for generating a strain; the final concentration of a product has competitiveness; in addition, trace tetracycline can be added during fermentation so as to achieve the aim of inhibiting part hybrid bacteria, greatly reduce the phenomenon of easily dyeing the hybrid bacteria during industrialization, shorten the fermentation time and lay a good foundation for industrialization production of the 3-hydracrylic acid by a microbe fermentation method.

The invention discloses a poly-3-hydroxy propionic acid copolymer and a production method thereof and belongs to the technical field of genetic engineering. According to the poly-3-hydroxy propionic acid copolymer and the production method thereof, a glycerol dehydratase gene and a glycerol dehydratase re-activating enzyme gene are integrated with a host strain genome by a gene integration technology, a polyhydroxy fatty acid synthase gene, a propionaldehyde dehydrogenase gene, a beta-ketoacyl coenzyme A thiolase gene, an acetoacetyl coenzyme A reductase gene and a propionyl coenzyme A synthetase gene are introduced, and a recombinant gene engineering strain has the ability of biologically synthesizing poly-3-hydracrylic acid-co-3-hydroxyvaleric acid. According to the poly-3-hydroxy propionic acid copolymer and the production method thereof, the poly-3-hydracrylic acid-co-3-hydroxyvaleric acid is obtained in a biosynthesis manner for the first time; compared with poly-3-hydracrylic acid, the obtained poly 3-hydracrylic acid-co-3-hydroxyvaleric acid has a higher melting point and lower crystallinity, has good degradability and can serve as a packaging material, a medical implant material, a drug sustained-release material and an electrochemical material.

The invention relates to a catalytic agent for preparing 1,3-PDO by performing hydrogenization on 3-hydracrylic acid methyl ester. The catalytic agent consists of the following components in percentage by weight: 55 to 80 wt% of CuO, 2 to 5 wt% of MnO2, 0.1 to 2 wt% of MoO3, 0.1 to 2 wt% of P2O5 and 15 to 40 wt% of SiO2. The catalytic agent prepared by the invention is used for the technology of preparing the 1,3-PDO by performing hydrogenization on the 3-hydracrylic acid methyl ester, the reaction condition is mild, the requirement on the content of organic acid and moisture in the raw material of the 3-hydracrylic acid methyl ester is low (less than 0.5 wt%), the selectivity of the 1,3-PDO is improved, the selectivity of the 1,3-PDO and ester exchange products is reduced, and meanwhile the catalytic agent is suitable for preparing the 1,3-PDO by performing hydrogenization on the 3-hydracrylic acid methyl ester in high concentration; the conversion rate of the 3-hydracrylic acid methyl ester is larger than 99%, and the yield coefficient of the 1,3-PDO is larger than 85%.

The invention relates to a method of synthesizing poly 3-hydracrylic acid by utilizing recombinant Escherichia coli and protects a recombinant Escherichia coli strain, a construction method of the recombinant Escherichia coli strain and a method of synthesizing the poly 3-hydracrylic acid by using the recombinant Escherichia coli strain by virtue of a biological method. The method has the beneficial effects that in the metabolic pathway of biologic synthesis of P3HP with glycerol serving as a substrate, NAD+, serving as coenzyme, can generate a great deal of NADH when used for catalyzing 3-hydroxy-propionaldehyde to produce 3HP; the oxidation-reduction disequilibrium in a recombinant strain, caused by increase of NADH is capable of inhibiting further increase of the yield of P3HP, and NADH can be consumed in the process that the recombinant Escherichia coli strain metabolizes glycerol to generate 1,3-PDO, and therefore synthesis of 1,3-PDO is introduced into the synthesis pathway of P3HP, the in-vivo reducing power of the strain can be balanced, the plasmid loss rate is effectively reduced, and the plasmid stability is kept.

The invention discloses a preparation method of a tea dyed costume fabric. By the use of fatty alcohol-polyoxyethylene ether, sodium citrate, hydroxypropyl methylcellulose, ethyl maltol and 2-hydracrylic acid, permeation of water is accelerated, so that tea polyphenol can quickly enter water, and the extraction time is shortened; 2-phosphonic acid butane-1,2,4-tricarboxylic acid sodium salt, sodium tetraphenylboron, 1,2,3,4,5,6-cyclohexanehexacarboxylic acid, sorbitol, ethanediol di(2-aminoethyl ether)quadrol enhance tea even dyeing, so that the dyeing is uniform and consistent, and the resistance to wet rubbing fastness of tea leaves is improved; hydroxypropyl guar gum trimethyl ammonium chloride, trehalose, glucosamine sulfate, 2,4,6-trichlorine benzoic acid and 4-hydroxy phenethylamine enhance the antibacterial property of chitosan, and the dyeing firmness is facilitated; ethylene diamine tetraacetic acid, L-cysteine, 4-hydroxyphenyl boronic acid, methoxyphenylboronic acid and hexamethylol melamine enhance the fixation effect of a tea dye, and the color fastness is enhanced; the costume fabric has high resistance to washing fastness, antibacterial property and resistance to dry and wet rubbing fastness.

The invention relates to a method for synthesizing 3-hydracrylic acid ester. The method mainly solves the problem that in the prior art, catalysts in a homogeneous system are difficult to separate. The method for synthesizing 3-hydracrylic acid ester includes the following steps that firstly, a ligand and cobalt carbonyl are subjected to a coordination reaction in an alcohol solvent to obtain turbid liquid of a catalyst; secondly, ethylene oxide and carbon monoxide are added, and a reaction is conducted to obtain 3-hydracrylic acid ester. According to the technical scheme, the ligand is selected from 4-vinylpyddine homopolymers or copolymers containing 4-vinylpyddine monomeric units, the technical problem is well solved, and the method can be used in industrial production of 3-hydracrylic acid ester.

The invention provides a method for using glyceric acid to prepare 3-hydroxypropionic acid. The method comprises the following steps that in a wild reaction condition, hydroiodic acid and glyceric acid are used for generating 3-iodopropionic acid in water; then 3-iodopropionic acid is extracted by using an organic solvent; and finally, a basic catalyst is used for catalyzing and hydrolyze 3-iodopropionic acid to be 3-hydracrylic acid. The reactants used in the method are cheap and easy to obtain, and the sources are green; the reaction time is short, efficient and energy saving effects are achieved; the amount of by-products is less, the yield rate of the first-step product 3-iodopropionic acid can reach 99%, and the yield rate of the second-step product 3-hydracrylic acid can reach 99%. The first-step product is separated by using the extraction method, and the extraction method is directly used in a two-phase system hydrolysis reaction in the second step. The product selectivity in the method is high, post-treatment is easy, and the method is easy to industrialize. The reaction system is simple, the reaction cost is low, and the preparation method has very important application value.

The invention discloses a tetramethyl guanidine hydroxy-acid salt composite desulfurizing agent and a preparation method thereof. The tetramethyl guanidine hydroxy-acid salt composite desulfurizing agent comprises the following components in percentage by mass: 50 to 85 percent of 1,1,3,3-tetramethyl guanidine, 10 to 45 percent of Alpha-hydroxy acid, 0.01 to 1 percent of free radical inhibitor, 0.05 to 2 percent of metal ion complexing agent, and 1 to 5 percent of viscosity reducer, wherein the Alpha-hydroxy acid is one or mixture of more than one of glycolic acid, Alpha-hydracrylic acid, Alpha-hydroxybutyric acid, phenyllactic acid, malic acid, citric acid and Alpha-hydroxy diacid. The desulfurizing agent has the advantages of high desulphurization effect, high by-product recovery value,light secondary pollution, reproducible and recycling absorption liquid and the like, has good economic benefit and environmental protection effect, and can be widely used in the thermal power generation field.

The invention discloses a method for producing R-(+)-3-(3,4-dihydroxyphenyl)-2-hydracrylic acid (D-tanshinol) through planococcus rifietoensis, and belongs to the technical field of bioengineering. By means of planococcus rifietoensis, D-tanshinol is catalytically prepared from substrates (cinnamic acid, cinnamyl aldehyde, cinnamyl alcohol, L-DOPA, L-tyrosine and L-phenylalanine). Specifically, the catalysis process A of adding the substrates to fermentation liquid in the liquid fermentation process or the catalysis process B of obtaining cells through liquid fermentation culture and putting the cells in a reaction system to catalyze the substrates is adopted. The method has good industrial application prospects.

The invention relates to a splitting method of 2-hydracrylic acid racemic mixture. The method comprises the following steps of: carrying out optical active alkali reaction on 2-hydracrylic acid racemic mixture and L-prolinamide, separating a single isomer L-prolinamide salt of 2-hydroxyl acrylic acid compound; and taking the single isomer of the 2-hydroxyl acrylic acid compound as important intermediate for synthetizing endothelin receptor antagonist for treating cardiovascular disease. Therefore, the single isomer with high optical purity is separated by the splitting method which is simple to operate and is provided by the invention; and the method is cheap in required material and reagent, and suitable for industrial production, and has good economic benefit.

The invention relates to a method for transforming Providencia microorganisms into levodopa to produce R-(+)-3-(3,4-dihydroxyphenyl)-2-hydracrylic acid. The method is simple in process and has significant industrial application value.

The invention discloses an alkali cyanide-free copper-plated anode dissolving accelerator and relates to a copper-plated anode. The accelerator comprises the following materials in parts by weight: 5-8 parts of accelerator A, 1-2 parts of accelerator B and 1-3 parts of accelerator C, wherein A is selected from 2-hydroxysuccinic acid(malic acid) and sodium salt or potassium salt thereof, or succinic acid (succinic acid) and sodium salt or potassium salt thereof; B is one substance selected from cis-butenedioic acid (maleic acid) and sodium salt or potassium salt thereof, trans-butenedioic acid (fumaric acid) and sodium salt or potassium salt thereof, and 2-hydracrylic acid(lactic acid) and sodium salt or potassium salt thereof; and C is one substance selected from malonic acid and sodium salt or potassium salt thereof, oxalic acid and sodium salt or potassium salt thereof, hydroxyacetic acid and sodium salt or potassium salt thereof, glutaric acid and sodium salt or potassium salt thereof, and adipic acid and sodium salt or potassium salt thereof. A, B and C are mixed to obtain the product. The alkali cyanide-free copper-plated anode dissolving accelerator can ensure that the anode dissolving is normal during a using process of a cyanide-free alkali copper-plating process using citrate or/and tartrate as complexing agent, and the plating solution is stably used for a long time.

The invention provides a preparing method for a glycolic acid-hydracrylic acid random copolymer. The preparing method includes the steps of raw material pretreatment, pre-polycondensation and polycondensation, wherein the step of raw material pretreatment includes the substeps that a glycolic acid water solution and a hydracrylic acid water solution are treated with ultrasonic waves and filtered; the step of pre-polycondensation includes the substep that the pretreated mixed solution is subjected to pre-polycondensation at low temperature and low pressure to obtain a pre-polycondensation intermediate product; the step of polycondensation includes the substep that butyl titanate and triphenyl phosphate are added into the pre-polycondensation intermediate product for polycondensation. By means of the improved raw material components and the optimized preparing technology, the prepared glycolic acid-hydracrylic acid random copolymer has stable quality, and is large in polymerization conversion rate, large in molecular weight, high in intrinsic viscosity and particularly suitable for manufacturing medical biodegradable macromolecular structure devices such as a biodegradable medical ligation clamp and a gastrointestinal tract anastomat .