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50results about How to "Improve synergistic antibacterial effect" patented technology
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Nanometer antibacterial agent loaded with both nano-silver and curcumin and preparing method and application thereof
ActiveCN106880593AOvercome the disadvantages of easy aggregationImprove solubilityAntibacterial agentsInorganic active ingredientsBiocompatibility TestingAntibacterial activity
The invention discloses a nanometer antibacterial agent loaded with both nano-silver and curcumin and a preparing method and application thereof. A polymeric micelle formed through self-assembly of the amphiphilic block copolymer PCL-b-PAsp is taken as a nano-carrier, positively charged Ag+ ions are adsorbed by means of the electronegativity of a PAsp chain segment in a hydrophilic shell and converted into nano-silver through in-situ reduction by means of a reductant, the natural and nontoxic antibacterial constituent curcumin is coated with hydrophobic core PCL, and in this way, the polymeric micelle loaded with both nano-silver and curcumin is formed and can be used for improving antibacterial activity. The nanometer antibacterial agent has high synergetic antibacterial efficiency for pseudomonas aeruginosa and staphylococcus aureus. The preparing method is simple, and raw materials have high biocompatibility and biodegradability, are cheap and easy to obtain and can be converted towards the clinical direction easily. Compared with a nanometer antibacterial agent loaded with either nano-silver or curcumin, the nanometer antibacterial agent loaded with both nano-silver and curcumin has the advantage that the synergetic pathogenic bacteria killing effect is good, and the anometer antibacterial agent loaded with both nano-silver and curcumin has broad application prospects.
Owner:INST OF RADIATION MEDICINE CHINESE ACADEMY OF MEDICAL SCI
Mint essential oil emulsion with high stability
ActiveCN108464998AImprove synergistic antibacterial effectGood antibacterial effectAntibacterial agentsCosmetic preparationsBiotechnologyEngineering
The invention discloses a mint essential oil emulsion with high stability and belongs to the technical field of food processing. The mint essential oil emulsion is prepared from mint essential oil, resveratrol, zein and pectin as raw materials, zein-pectin nanoparticles into which resveratrol are embedded are prepared by using an inverse-phase solvent method, and a stable mint essential oil emulsion is prepared by using a high-pressure homogenization method. The embedding rate of the emulsion to the resveratrol is up to 80% or greater, in addition, the resveratrol and the mint essential oil have synergetic antibacterial effects, and meanwhile, due to addition of the pectin, the stability of the resveratrol can be improved. The invention provides a method of co-embedded essential oil and amphipathic functional factors, and further provides a method for improving the stability of the resveratrol and preparing an antibacterial agent with the resveratrol and the mint essential oil. The method is simple to operate and easy in industrial popularization.
Owner:JIANGNAN UNIV +1
Microcapsule containing plant characteristic aroma and preparation method of microcapsule
InactiveCN109999736AImprove antibacterial propertiesRich fragranceBiocideTobacco treatmentTreatment feverEffective time
The invention provides a microcapsule containing a plant characteristic aroma and a preparation method of the microcapsule. The microcapsule is prepared from, by weight, 3-7 parts of fever-trees, 15-25 parts of orange peel, 1-5 parts of thyme, 1-4 parts of vanilla, 3-6 parts of cortex cinnamomi and 10-20 parts of lavandula angustifolia. The microcapsule has the advantages that various materials have mutual synergistic effects, synergize with one other and mutually enhance the antibacterial properties, thereby enhancing the antibacterial property of the microcapsules; by adding plant extracts such as the orange peel and the lavandula angustifolia, the aroma of the microcapsule is enriched, and the effective time of air freshening is greatly prolonged.
Owner:DONGGUAN XIAOSEN ENVIRONMENTAL PROTECTION PACKAGING MATERIAL
Artificial tooth root with synergistic antibacterial coating and preparation method of artificial tooth root
ActiveCN110302418AHigh bonding strengthGood biocompatibilityTransportation and packagingMetal-working apparatusIon exchangeUltraviolet lights
The invention relates to an artificial tooth root with a synergistic antibacterial coating and a preparation method of the artificial tooth root. The artificial tooth root with the synergistic antibacterial coating is composed of a titanium or titanium alloy artificial tooth root matrix and a lamination nanostructure TiO2 coating loaded with silver nanoparticles (AgNPs) and graphite like carbon nitride (g-C3N4) on the surface. The preparation method includes the steps that firstly, rod-shaped nanostructure sodium titanate is prepared on the surface of titanium or a titanium alloy by a hydrothermal synthesis technology; secondly, the AgNPs is loaded on the surface of the rod-shaped nanostructure sodium titanate by an ion exchange technology and an ultraviolet light reduction method; thirdly, the silver loaded sodium titanate is transformed into the TiO2 bioactive coating loaded with the AgNPs on the surface by a high-temperature annealing process; and finally, a chemical vapor deposition technology is used for depositing g-C3N4, and the surface of the TiO2 bioactive coating is transformed into lamination nanostructure TiO2 coating with g-C3N4 / Ag, therefore, the artificial tooth rootwith the synergistic antibacterial coating is obtained.
Owner:SOUTHWEST UNIVERSITY
Florfenicol/colistin sulfate soluble powder and preparation method thereof
ActiveCN103550755AGood synergistic antibacterial effectEasy to useAntibacterial agentsPowder deliveryAntibacterial actionPoloxamer
The invention discloses a florfenicol / colistin sulfate soluble powder which is composed of the following components in percentage by weight: 5-20% of florfenicol, 2-20% of colistin sulfate, 0.5-2% of borax, 5-30% of citric acid, 0.1-2% of potassium bicarbonate, 7.5-30% of polyvinylpyrrolidone, 1-5% of poloxamer 188 and the balance of anhydrous glucose. The invention also discloses a preparation method of the soluble powder, which comprises the following steps: dissolving the polyvinylpyrrolidone in anhydrous ethanol, adding the florfenicol, citric acid, borax, potassium bicarbonate and poloxamer 188, evenly mixing, recovering the ethanol, drying, pulverizing, adding the colistin sulfate and anhydrous glucose, and evenly mixing. The soluble powder ensures that the two reagents simultaneously enter the organism and better display the synergic antibacterial action; the method is simple and convenient to operate, and enhances the production efficiency; and the anhydrous ethanol is recovered, so the method protects the environment and is suitable for industrial production.
Owner:HENAN SOAR VETERINARY PHARMA
Composition of total saponins of panax notoginseseng and fluconazole of anti-candida albicans and drug-resisting bacterial strain and application of composition
ActiveCN106309526AReduce dosageEliminate side effectsOrganic active ingredientsAntimycoticsSide effectCandida famata
The invention relates to a composition of total saponins of panax notoginseseng and fluconazole of an anti-candida albicans and drug-resisting bacterial strain and application of the composition. The composition is prepared from the fluconazole and the total saponins of panax notoginseseng, wherein the weight ratio of the fluconazole to the total saponins of panax notoginseseng is 1 to (2 to 16). When the total saponins of panax notoginseseng and the fluconazole are combined, the composition has a remarkable synergistic antibacterial effect on drug-resisting candida albicans, so that the total saponins of panax notoginseseng can be used for replacing part of the fluconazole, the usage of the fluconazole is reduced and the toxic and side effect and drug resistance, caused by the fluconazole, are reduced; meanwhile, an anti-fungus effect is remarkably enhanced and the composition has a wide application prospect on clinic.
Owner:SHANGHAI TONGJI HOSPITAL
Nano polyaniline/ZnO composite antibacterial agent and preparation method thereof
InactiveCN102783500ASimple preparation processLow costBiocideDisinfectantsBactericidal effectActive agent
The invention discloses a nano polyaniline / ZnO composite antibacterial agent and a preparation method of the nano polyaniline / ZnO composite antibacterial agent. According to the invention, the quick mixing method to synthesize precursor polyaniline / Zn(OH)2 by one step is used, the precursor is dried and then the polyaniline / ZnO composite antibacterial agent is obtained; the polyaniline exists in a nano-fiber manner; zinc oxide exists in a spherical structure with diameter of 20-200nm; the nano polyaniline / ZnO composite antibacterial agent provided by the invention has excellent bactericidal action for different strains such as escherichia coli, staphylococcus aureus and bacillus subtilis. The composite antibacterial agent is low in material cost, simple in preparation and good in thermal stability; the nano ZnO particle has uniform distribution and large specific surface area; the problem that the harmful components such as surfactant, stabilizer and so on are added during the preparation process of the nano ZnO antibacterial agents on the market can be overcome; the antibacterial agent has excellent biocompatibility, has no toxicity and harmfulness for body, is easy to commercially produce and has high economic and social value.
Owner:KUNMING UNIV OF SCI & TECH
Graphene composite antibacterial cat litter material and preparation method thereof
InactiveCN111264401AImprove antibacterial propertiesMicro electrolytic degradation is goodAnimal housingSodium bicarbonateGraphene flake
The invention relates to the field of pet supplies, and specifically relates to a graphene composite antibacterial cat litter material and a preparation method thereof. The cat litter material is prepared from, in parts by weight, 1-10 parts of a composite antibacterial material, 20-80 parts of an environmental mineral material and 1-10 parts of an active cementing material; the composite antibacterial material is prepared from nano graphene sheets, nanometer iron powder, nano copper powder and nano cerium oxide; the nano graphene sheets are multi-layer nano graphene sheets, and the particle sizes are 50-500 nm; the environmental mineral material is prepared from volcanic ash, bentonite, zeolite, nano titanium dioxide, fly ash and sodium bicarbonate; the nano titanium dioxide is anatase titanium dioxide, and the particle sizes are 50-500 nm; and the active cementing material is prepared from gypsum powder and deionized water. The prepared cat litter material is good and lasting in antibacterial property, good in deodorizing effect, safe and environmentally-friendly; and the preparation method is scientific, reasonable, simple and easy to operate.
Owner:淄博木烯新材料科技有限公司
New use of fumigacin type steroids in producing medicine for anti-drug fast bacteria
InactiveCN1943580AAddressing drug resistanceGood synergyAntibacterial agentsTetracycline active ingredientsSide effectBacteria
The invention discloses a new uses of helvolicacid sterides in making drugs of antibiotic-resistant microbes, including helvolicacid, fusidic acid and its salt and salt hydrates acceptable in pharmacology, compound of ester or prodrug with single or multi-antibiotic, applying to preparation of drugs of antibiotic-resistant microbes.
Owner:CHENGDU INST OF BIOLOGY CHINESE ACAD OF S
Child aldehyde-free antibacterial water-based diatom coating and preparation method thereof
ActiveCN109401584AHigh affinityReduce allergy riskAntifouling/underwater paintsPaints with biocidesWater basedSolvent
The invention discloses child aldehyde-free antibacterial water-based diatom coating and a preparation method thereof. The child aldehyde-free antibacterial water-based diatom coating takes deionizedwater as a solvent and does not contain organic solvents, titanium dioxide, nano-ZnO loaded diatomite and nano-WO3 loaded diatomite are added, formaldehyde is further effectively absorbed and decomposed, allergy harm of the coating to children is effectively reduced and eliminated, and the coating is safe and environmentally friendly; and nano ZnO and nano WO3 compounding is adopted in the diatomite, and thus the good synergistic antimicrobial and durable antimicrobial performance is achieved. By reasonably adjusting the proportion of all components, the compatibility of all the components ofthe coating is good, the stability of the coating is improved, the mechanical properties of a coating film can be effectively improved, and the coating is resistant to scratching and scrubbing.
Owner:广东太氧谷环保科技有限公司
Preparation method of shell powder loaded antibacterial material
InactiveCN110973160AImprove adsorption capacityImprove effective utilizationBiocideDisinfectantsFiltrationDistilled water
The invention discloses a preparation method of a shell powder loaded antibacterial material, which comprises the following steps: S1, pretreating a shell powder carrier: ultrasonically cleaning shells, soaking in an alkaline solution, cleaning with distilled water, drying, pulverizing in a multifunctional pulverizer, calcining in a muffle furnace, and grinding in a mortar to obtain the shell powder carrier; S2, preparing a composite material: putting a titanium salt into a flask, adding distilled water for dissolving, and stirring at a constant temperature until a milk white precipitate is generated; adding distilled water to dissolve the shell powder to obtain a shell powder solution, magnetically stirring and dispersing, and adding the shell powder solution into the flask; selecting a zinc salt, dissolving the zinc salt, pouring an obtained zinc salt solution into an alkali liquor, stirring and mixing, dropwise adding an obtained mixed liquor into the flask, stirring at constant temperature, taking an obtained product out, carrying out suction filtration, washing and constant-temperature drying on the product, dehydrating and molding the product, and calcining the product in a muffle furnace to prepare the shell powder / TiO2 / ZnO composite material. The inorganic antibacterial agent is prepared by taking the shell powder as the carrier of the antibacterial material to load thenano oxide, so that the application field of the shell is expanded.
Owner:GUANGXI TEACHERS EDUCATION UNIV
Yeast expressed chicken Cathelicidin antibacterial peptide as well as preparation method and application thereof
PendingCN105732792AAvoid killing effectEasy to separate and purifyAntibacterial agentsFungiPichia pastorisBiotechnology
The invention belongs to the field of biotechnology and particularly relates to pichia pastoris expressed recombinant chicken Cathelicidin antibacterial peptide and further discloses a preparation method and application thereof. In the method for preparing recombinant chicken Cathelicidin antibacterial peptide disclosed by the invention, a pPICZalphaA secreted expression vector is selected as a eukaryotic expression system of the exogenous gene so that the recombinant chicken Cathelicidin antibacterial peptide is efficiently expressed and direct killing of host cells caused by the expression product is avoided. Meanwhile, the method has the advantages of high expression efficiency, simple separation and purification of expression products, low production cost, easiness in magnification and good stability and is suitable for large-scale industrial production. According to experimental verification, the combination of Cathelicidin antibacterial peptide and antibiotic realizes an obvious synergistic antibacterial effect on multiple kinds of gram-positive bacteria and gram-negative bacteria, and the application and promotion prospects are broad.
Owner:POULTRY INST SHANDONG ACADEMY OF AGRI SCI
Mixed preparation with bacteriophages LPEE17 and LPEK22 as major components and application
ActiveCN110317793AGood antibacterial effectIncrease temperatureMicroorganism based processesOther dairy technologyEscherichia coliFood safety
The invention relates to the field of food safety, and particularly discloses a mixed preparation with bacteriophages LPEE17 and LPEK22 as major components and application. The two coliphages LPEE17 and LPEK22 are provided, and both the coliphages are virulent bacteriophages and can be used for lysing colibacillus with drug resistance, wherein the LPEE17 can lyse the colibacillus O157:H7, and theLPEK22 can lyse the colibacillus O157:H7 and also can lyse serotype salmonella typhimurium and serotype salmonella enteritidis. The antibacterial effects of the LPEE17 and LPEK22 on the colibacillus EDL933 in milk and ham sausages under single use and mixed use conditions are compared, the mixed bacteriophages have a better antibacterial effect in the foods, and a significant synergistic effect isachieved.
Owner:HUAZHONG AGRI UNIV
Antibacterial type nano-fiber-based fresh-keeping film and preparation method thereof
The invention discloses an antibacterial type nano-fiber-based fresh-keeping film which is composed of the following raw materials by weight: 1-2 parts of sodium tripolyphosphate, 130-150 parts of polyethylene, 1-2 parts of mannan, 10-14 parts of nano crystalline cellulose, 4-7 parts of cellulose acetate propionate, 10-14 parts of methyl ester nylon acid, 1-2 parts of 8-hydroxyquinoline, 0.7-1 part of Diisopropylethanolamine, 5-8 parts of Triethylene Glycol Di-2-ethylhexoate, 3-4 parts of sucrose acetate isobutyrate, 5-7 parts of allylpolyethyleneglycol, 10-20 parts of diatomite, 40-50 parts of a bacteriostatic water dispersion and 2-3 parts of Hydroxyethylidene-1,1-diphosphonic acid, after the added diatomite is modified by esterification, the diatomite is well compatible with a polymer matrix, and effectively improves the stability strength of a finished film, and the antibacterial type nano-fiber-based fresh-keeping film has good toughness, good antibacterial activity, good use safety and excellent comprehensive performance.
Owner:福州永鑫塑料包装用品有限公司
Gynecological gel containing chitosan oligosaccharide and preparation method thereof
ActiveCN108066278BImprove synergistic antibacterial effectMaximize the synergistic antibacterial effectAerosol deliveryOintment deliveryAntimicrobial drugMedicine
Owner:GUANGZHOU RAINHOME PHARM&TECH CO LTD
Preparation method of polylactic acid material with anti-adhesion and sterilization functions
ActiveCN113461995AGood antibacterial durabilityBroad-spectrum and long-lasting antifouling and antibacterial functionAntifouling/underwater paintsPaints with biocidesSolventChemistry
The invention discloses a polylactic acid material with anti-adhesion and sterilization functions, which is prepared by the following steps: 1) stirring and dissolving a biodegradable material polylactic acid in a good solvent, adding a poor solvent to realize phase separation, and fully stirring to obtain a coating solution; 2) uniformly coating a polylactic acid sheet with the solution obtained in the step 1), and drying; 3) stripping the top layer polylactic acid by using an adhesive tape to obtain a super-hydrophobic surface; and 4) dispersing chlorophyll in absolute ethyl alcohol, coating on the super-hydrophobic surface of polylactic acid, and drying. The surface of the material has the super-hydrophobic performance of resisting initial adhesion of bacteria, and the adhered bacteria can be killed through photodynamic force. A super-hydrophobic and photodynamic synergistic antibacterial mode is adopted, the dosage of a bactericide is small, the sterilization efficiency is high, the antibacterial long-term effect is good, the controllability is high, and bacteria cannot be induced to generate drug resistance. The polylactic acid material with anti-adhesion and sterilization functions prepared by the invention is non-toxic and harmless, has good biological and environmental compatibility, and can be used in the aspect of bacterial infection resistance of medical or packaging materials.
Owner:ZHENGZHOU UNIV
Sulbactam sodium composition freeze-dried powder for injection
InactiveCN103536561AImprove synergistic antibacterial effectImprove body distributionAntibacterial agentsPowder deliveryChemistryFreeze dry
The invention provides a sulbactam sodium composition freeze-dried powder for injection, and belongs to the field of medicine and medicine preparation technology. The sulbactam sodium composition freeze-dried powder comprises following raw material ingredients, by weight, 7.26 to 9.17 parts of sulbactam sodium, 6.02 to 7.97 parts of chitosan nanoparticle, and 81.34 to 87.55 parts of injection water. Advantages of the sulbactam sodium composition freeze-dried powder are that: 1) the sulbactam sodium composition freeze-dried powder possesses excellent synergistic antimicrobial effect with sulbactam sodium, antibiotic sensitive rate of various bacteria on the sulbactam sodium composition freeze-dried powder is high; 2) stability of sulbactam sodium against beta-lactamase is increased, and in vivo distribution is excellent; 3) improvement of activity is capable of shortening medication cycle of patients, and reducing occurrence likelihood of adverse reaction caused by accumulation of sulbactam sodium; and 4) the chitosan nanoparticle can be used as a freeze-dried skeleton agent of the freeze-dried powder injection instead of mannitol so as to avoid active effects of mannitol on human bodies.
Owner:HAINAN WEI KANG PHARMA QIANSHAN
Yeast expressed chicken antibacterial peptide Cathelicidin 2 and preparation method and application thereof
InactiveCN105753959AAvoid killing effectEasy to separate and purifyAntibacterial agentsFungiBiotechnologyPichia pastoris
The invention belongs to the biotechnology field, particularly relates to a pichia pastoris-expressed recombinant chicken antibacterial peptide Cathelicidin 2, and further discloses a preparation method and application thereof.According to the preparation method of the recombinant chicken antibacterial peptide Cathelicidin 2, pPICZ alpha A secreting type expression vector is selected as an eukaryotic expression system of exogenous genes, the recombinant chicken antibacterial peptide Cathelicidin 2 is effectively expressed, and direct destruction caused by an expression product on host cells is avoided.Meanwhile, the method is high expression efficiency, the expression product is easy to separate and purify, the production cost is low, enlarging is easy, stability is good, and the method is suitable for large-scale industrial production.Experiments prove that the antibacterial peptide Cathelicidin 2 has the obvious synergistic antibacterial effect when used in cooperation with antibiotics, and has the wide application and popularization prospect.
Owner:POULTRY INST SHANDONG ACADEMY OF AGRI SCI
Nano polyaniline/ZnO composite antibacterial agent and preparation method thereof
The present invention disclosed a nano -polyiline / ZnO composite antibacterial agent and its preparation method. The invention adopts a fast mixed method to synthesize the precursor polyiline / Zn (OH) 2, and then dry the polyiline / ZNO composite antibacterial agent;Ailine exists in the form of nano -fiber, and zinc oxide exists in a ball -shaped structure with a diameter of 20 ~ 200nm; the nano -polyiline / ZnO composite antibacterial agent provided by the present invention pairs of E. coli, Staphylococcus aureus, Bacillus, etc.They all have excellent sterilization effects.The cost of raw materials for this composite antibacterial agent is low, simple preparation, and good thermal stability. The nano ZNO particles are evenly distributed and larger than the surface area.The disadvantages, at the same time, have excellent biocompatibility, are non -toxic, harmless to the human body, are easy to industrialized, and have high economic and social value.
Owner:KUNMING UNIV OF SCI & TECH
High-antibacterial and wear-resisting PVC (Polyvinyl Chloride) resin material and preparation method thereof
InactiveCN108864618AGood plasticizing effectStrong antibacterial effectChemistryAntibacterial effect
The invention relates to the technical field of high molecular materials and relates to a high-antibacterial and wear-resisting PVC (Polyvinyl Chloride) resin material and a preparation method thereof. The high-antibacterial and wear-resisting PVC resin material is prepared from the following components in parts by weight: 100 parts of PVC resin, 10 to 40 parts of an antibacterial plasticizer, 8 to 12 parts of a stabilizer, 1 to 3 parts of a lubricant, 5 to 8 parts of an antioxidant, 3 to 5 parts of an anti-impact modifying agent, 5 to 20 parts of filler and 1 to 3 parts of an additive. According to the high-antibacterial and wear-resisting PVC resin material and the preparation method thereof, an antibacterial functional auxiliary agent and a plasticizing-promoting auxiliary agent are integrated, have a good plasticizing effect and a relatively strong antibacterial effect, and are matched with other components to have a mutual synergistic effect, so that the PVC material has a good antibacterial effect and good mechanical properties and weather-resisting performance; the application field and application field of PVC are greatly improved; furthermore, the preparation method provided by the invention is simple, preparation technological conditions are easy to control and the preparation efficiency is high; the raw material price and the production energy consumption are relatively low, so that the preparation method is suitable for large-scale production.
Owner:界首市海钰塑化有限公司
New use of fumigacin type steroids in producing medicine for anti-drug fast bacteria
InactiveCN1943580BAddressing drug resistanceGood synergyAntibacterial agentsTetracycline active ingredientsSide effectBacteria
The invention discloses a new uses of helvolicacid sterides in making drugs of antibiotic-resistant microbes, including helvolicacid, fusidic acid and its salt and salt hydrates acceptable in pharmacology, compound of ester or prodrug with single or multi-antibiotic, applying to preparation of drugs of antibiotic-resistant microbes.
Owner:CHENGDU INST OF BIOLOGY CHINESE ACAD OF S
Method for prolonging shelf life of bread product
InactiveCN108606040AGood antiseptic and bactericidal abilityThe equipment is easy to operatePreservation by coatingNatamycinSterile environment
The invention discloses a method for prolonging shelf life of a bread product so as to solve the problems that conventional bread products are easy to pollute by moulds and short in shelf life. According to the method disclosed by the invention, epsilon-polylysine and natamycin are used as fresh keeping materials to prepare an antiseptic fresh keeping agent having the effect of synergistically resisting bacteria, then the antiseptic fresh keeping agent is applied to the surface of bread in a spraying manner, the bread is placed at room temperature under sterile environment for natural airing,and then sealing and packaging are performed. Through adoption of the method disclosed by the invention, the operation is extremely simple and convenient, the fresh keeping effect is good, the methodis healthy, safe and harmless to human bodies, is low in cost and is suitable for enterprises to popularize and apply; satisfactory antiseptic fresh keeping effects are provided; and besides, lysine necessary for human bodies can also be provided.
Owner:樟树市狮王生物科技有限公司
Method for inactivating Listeria monocytogenes in food by cooperating ultrahigh pressure with antibacterial agent
PendingCN110353154AReduce treatment conditionsGood killing effectBacteriaMicrobiological testing/measurementListeria monocytogenesAntibacterial agent
The invention discloses a method for inactivating Listeria monocytogenes in food by cooperating ultrahigh pressure with an antibacterial agent. The method comprises the following steps of (1) LB1 andLB2 liquid culture medium preparation; (2) Listeria monocytogenes inoculating and activating, wherein the Listeria monocytogenes is inoculated into an LB1 liquid culture medium for culture through a slant culture medium to obtain an LB1 bacterial solution, and the LB1 bacterial solution is taken and added into an LB2 liquid culture medium to obtain an LB2 bacterial solution; (3) ultrahigh pressuretreatment, wherein the antibacterial agent is added into a Listeria monocytogenes solution separately to obtain a bacterium suspension of Listeria monocytogenes, vacuum sterile sealing is conducted on the suspension, and ultrahigh pressure treatment is conducted; (4) counting, wherein the Listeria monocytogenes obtained after ultrahigh pressure treatment is cultured and counted. Accordingly, theinactivation effect is greatly improved, the sublethal damage rate is as low as 15.24%, and the lethal rate is up to 100%; the control over the sublethal state of the Listeria monocytogenes is achieved, and the treatment pressure can be reduced.
Owner:CHINA PHARM UNIV
Nano antibacterial bone filling materials and production method thereof
InactiveCN105214142AImprove synergistic antibacterial effectHigh porosityProsthesisChemistryGlycerol
The invention discloses nano antibacterial bone filling materials and a production method thereof. The bone filling materials comprise hydroxyapatite, nano silver powder, nano titanium dioxide, glycerol, polyvinyl acetate, lemongrass extract, nano silicon dioxide and epoxy resin. The production method includes: mixing the hydroxyapatite, the nano silver powder, the nano titanium dioxide, the nano silicon dioxide and the epoxy resin, then grinding into 800-mesh powder, adding into a reaction kettle, heating at a constant speed to 2000-2500 DEG C, keeping the temperature for 5-10 minutes, and heating to 2800 DEG C to obtain first mixed liquid; adding the glycerol and the lemongrass extract when the first mixed liquid is cooled to 40-50 DEG C, and evenly stirring to obtain the nano antibacterial bone filling materials. The nano antibacterial bone filling materials are high in porosity, good in antibacterial effect, and capable of accelerating bone healing and reducing the pain of patients.
Owner:SUZHOU COSMETIC MATERIALS
Cefuroxime sodium composition freeze-dried powder for injection
InactiveCN103536565AImprove synergistic antibacterial effectReduce the possibility of adverse reactionsAntibacterial agentsPowder deliveryChitosan nanoparticlesFreeze-drying
The invention provides a cefuroxime sodium composition freeze-dried powder for injection, and belongs to the field of medicine and medicine preparation technology. The cefuroxime sodium composition freeze-dried powder comprises following raw material ingredients, by weight, 7.26 to 9.17 parts of cefuroxime sodium, 6.02 to 7.97 parts of chitosan nanoparticle, and 81.34 to 87.55 parts of injection water. Advantages of the cefuroxime sodium composition freeze-dried powder are that: 1) the cefuroxime sodium composition freeze-dried powder possesses excellent synergistic antimicrobial effect with cefuroxime sodium, medicine bioavailability is increased, and administration dosage is reduced; 2) dosage of auxiliary materials is less, freeze-drying formability is excellent, and stability of cefuroxime sodium against beta-lactamase is increased; and 3) the cefuroxime sodium composition freeze-dried powder is safe for application, curative effect is accurate, quality is controllable, and occurrence likelihood of adverse reaction caused by accumulation of cefuroxime sodium is reduced.
Owner:HAINAN WEI KANG PHARMA QIANSHAN
A kind of compound antibacterial coating material, preparation method and application thereof
ActiveCN106085226BImprove antibacterial propertiesImprove synergistic antibacterial effectAntifouling/underwater paintsPaints with biocidesPolymer scienceGallic acid ester
Owner:CHENGDU BOYAN TECH CO LTD
Processing method of fishes
PendingCN109845807AHas antibacterial propertiesGood dissolution environmentMeat/fish preservation using chemicalsPreservativeGlycerol
The invention relates to a processing method of fishes. The method comprises the following steps: (1) carrying out rough processing treatment on raw material fishes; and (2) carrying out fresh-keepingtreatment on the raw material fishes after the rough processing treatment. The fresh-keeping treatment specifically comprises the following steps: firstly, treating the raw material fishes by adopting a composite biological preservative, and then transferring the fishes to a cold storage for cold storage. The composite biological preservative is prepared from the following raw materials in partsby weight: 5-8 parts of lysozyme, 10-12 parts of nisin, 8-12 parts of fish bone peptide, 8-10 parts of glycerol, 15-20 parts of sodium chloride and 95-105 parts of water. The processing method of fishes provided by the invention has the advantages that good antibacterial performance can be guaranteed and the fishes are easy to clean. Meanwhile, the method has convenient process operation, and short processing time.
Owner:福州宏东食品有限公司
A kind of formaldehyde-free antibacterial water-based diatom coating for children and preparation method thereof
ActiveCN109401584BHigh affinityReduce allergy riskAntifouling/underwater paintsPaints with biocidesOrganosolvEngineering
The invention discloses child aldehyde-free antibacterial water-based diatom coating and a preparation method thereof. The child aldehyde-free antibacterial water-based diatom coating takes deionizedwater as a solvent and does not contain organic solvents, titanium dioxide, nano-ZnO loaded diatomite and nano-WO3 loaded diatomite are added, formaldehyde is further effectively absorbed and decomposed, allergy harm of the coating to children is effectively reduced and eliminated, and the coating is safe and environmentally friendly; and nano ZnO and nano WO3 compounding is adopted in the diatomite, and thus the good synergistic antimicrobial and durable antimicrobial performance is achieved. By reasonably adjusting the proportion of all components, the compatibility of all the components ofthe coating is good, the stability of the coating is improved, the mechanical properties of a coating film can be effectively improved, and the coating is resistant to scratching and scrubbing.
Owner:广东太氧谷环保科技有限公司
Method for preparing nanometer silver composite sol
Owner:北京首纳东方科技有限公司 +1
Degradable cleansing tablet material for removable denture
InactiveCN109431891AReduce cleaningDisintegrates quicklyCosmetic preparationsToilet preparationsCyclodextrinPolyethylene glycol
The invention discloses a degradable cleansing tablet material for a removable denture. The degradable cleansing tablet material is prepared from the following raw materials: dandelion extract, triethyl citrate, polyethylene glycol, polysorbate, polyvinyl pyrrolidone, sodium alginate, xanthan gum, cyclodextrin, hydroxymethyl cellulose, methyl p-hydroxybenzoate, propionyl glycerol monopalmitate, radix puerariae arrow root powder, sodium citrate, sodium pyrophosphate, natrium aceticum, sodium stearyl fumarate, tea extract and quicklime powder. The degradable cleansing tablet material for the removable denture disclosed by the invention is an anti-bacterial stain removal denture cleansing tablet material which is high in cleaning efficiency, quick in disintegration time, cheap in price and elegant in fragrance, and can quickly and effectively remove dirt and bacteria from the removable denture.
Owner:蚌埠佳美仕义齿有限公司
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