166results about How to "Easy to achieve industrial scale production" patented technology

The invention belongs to the field of a heat conducting polymer-based composite, and particularly relates to a graphene-containing silicone rubber composite material with the high thermal conductivity and a preparation method thereof. The composite material comprises a matrix, a heat conducting filler and a vulcanizing agent. The preparation method comprises the following steps: mixing at a room temperature so as to obtain a mixed rubber material; and carrying out hot press molding and one-stage vulcanization on the mixed rubber material by using a flat vulcanizing machine, and putting in a drying oven, carrying out two-stage vulcanization, thus obtaining the silicone rubber composite material with the high thermal conductivity. As graphene is high in thermal conductivity and has a unique two-dimensional lamellar structure, an interconnected heat conducting network is easy to form in the composite material, and the thermal conductivity of the silicon rubber composite material is obviously increased; and the thermal conductivity of the graphene-containing silicone rubber composite material is 0.3W / m.K-1.5W / m.K, and the hardness of the silicone rubber composite material can be reduced. The graphene-containing silicone rubber composite material with the high thermal conductivity is simple in preparation technology, high in production efficiency and easy for the realization of industrialization mass production, and meanwhile, a direction is pointed out for the batch application of graphene.

The invention discloses a preparation method of a layered structure molybdenum disulfide / carbon composite material and an application. The composite material is prepared by adopting a molybdenum oxide organic / inorganic hybrid compound of an organic amine intercalation layer as a precursor, putting the precursor into a high-temperature area, putting a sulfur source into a low-temperature area and simultaneously carrying out high-temperature vulcanization and carbonization treatment under inert gas protection. The composite material has a layered structure; carbon is located between laminated plates of a few of molybdenum disulfide layers; the composite material can serve as an electronic transmission channel to improve the conductivity of the electrode material; and furthermore, the interlayer distance is expanded and the diffusion ability of Li<+>between the layers is improved. The composite electrode material has relatively high specific capacity and good cycle performance and rate capability, and is simple in process and low in raw material cost; and large-scale industrial production is easy to implement.

The invention belongs to the technical field of a lithium ion battery, and relates to a preparation process of lithium ion battery negative paste, a lithium ion battery negative pole plate and a lithium ion battery. The preparation process of the lithium ion battery negative paste comprises the following steps of (a) mixing a negative active substance, a conductive additive, a dispersion agent anda thickening agent in a dried way to obtain mixed powder; (b) adding a solvent, performing uniform mixing to obtain primary paste with solid content being 67-69wt%; (c) adding the solvent again, performing uniform mixing to obtain secondary paste with solid content being 58-62wt%; (d) adding the solvent again, performing uniform mixing to obtain third paste with solid content being 54-56wt%; and(e) adding a binding agent into the third paste, and performing uniform mixing to obtain the lithium ion battery negative paste. The process is simple and is easy to operate, the preparation time canbe remarkably prepared, the equipment utilization ratio is improved, meanwhile, the mixing is uniform, and the dispersion performance, the consistency and the fineness of the paste are improved.

The invention relates to a catalyst used for preparing glycol from hydrogenation of oxalates and a preparation method thereof. The invention is characterized in that carbon nano tubes are added in hydrogenation of oxalates catalyst for preparing efficient carbon nano tube glycol copper-silicon based catalyst with promoting effect for hydrogenation of oxalates, which has environmentally friendly features, high activity and high selectivity. The catalyst contains copper, silicon dioxide and carbon nano tubes. The chemical formula of the catalyst is xCu / SiO2-yCNTs, wherein x% indicates that the mass percent of copper in the catalyst is x%, y% indicates that the mass percent of the carbon nano tubes in the catalyst is y%, and CNTs indicates multi-wall carbon nano tubes. The catalyst contains the ingredients in mass percent: 5-60 of Cu, 0.5-30 of CNTs and balance of SiO2. The catalyst is prepared in a method of coprecipitation, and is obtained after oven-drying, furnacing and reduction.

The invention belongs to the field of health beverages, and in particular relates to a gynura procumbens compound preparation as well as a preparation method and application thereof. The gynura procumbens compound preparation is characterized by being prepared from the following raw materials in percentage by weight: 75-85% of gynura procumbens, 5-10% of barley seedlings, 3-6% of common lophatherum herb, 2-5% of frostbitten mulberry leaves, 2-4% of kudzuvine root and 1-3% of poria cocos. The preparation method of the gynura procumbens compound preparation comprises the following steps: performing weighing, drying and small fire baking on gynura procumbens, then mixing with other weighed raw materials, and crushing. The preparation disclosed by the invention is safe, healthy and natural, has various effects of treating gout in multiple ways comprehensively, can play roles in adjusting uric acid metabolism, promoting excretion of uric acid, preventing uric acid crystallization, diminishing inflammation and relieving pain, and controlling arthralgia, swelling and inflammations in an attack stage of gout, also can be used for reducing the blood lipid and blood sugar and strengthening kidney metabolism, can be used for treating both symptoms and root causes and achieving the effects of preventing and treating gout, and has the characteristics of natural compounds and natural health maintenance; and the preparation method disclosed by the invention is simple and convenient, and can be used for keeping original components of the raw materials to the greatest extent.

The invention relates to a composite material of vacuum churning composite granule enhanced aluminum matrix and a preparation technique, which comprises: Si 0-15Wt%, Mg 0-1.5Wt%, Cu 0-2.0Wt%, Mn 0-1.0Wt%, Cr 0-0.4Wt%, Ti 0-0.2Wt%, SiC 0.1-20% (volume proportion). Firstly base alloy is smelted, slag is removed, and refined, churned slowly in vacuum to complete degassing procedure for base melt, the pre-treated enhanced granule is continuously added into the aluminum base melt, mechanical churning to roll the granule into the melt, after the granule is completely rolled in the melt, strong churning and slow churning in reverse direction are conducted so as to disperse the granule evenly in the base; the temperature raises, modifier and refiner are added; the vacuum is dismounted, and placed in static, the floating slag is removed above the melt, and cast. The composition between the granule and the base is realized via vacuum mechanical churning, the joining interface is good, the enhanced granule is evenly dispersed in the base, the prepared composite material has low porosity rate, which is easy to realize industrial mass production.

The invention belongs to the field of polymer composite materials, and in particular relates to a composite conductive film taking graphene as a conductive agent and a preparation method of the composite conductive film. The composite conductive film is prepared by premixing polyvinyl chloride and graphene and then performing mixing in a double-roll mixing mill. The preparation method comprises the steps of firstly, adding a stabilizing agent and a plasticizing agent into polyvinyl chloride resin, stirring uniformly, and then curing the mixture in a drying oven; then, adding graphene into the mixture, and stirring uniformly; finally, mixing in the double-roll mixing mill to obtain a graphene / polyvinyl chloride composite conductive film, wherein the content of two-dimensional graphene in the composite material is 0.5-4.5wt%. The polymer base conductive composite material taking graphene as the conductive agent, provided by the invention, has the characteristics of light weight, corrosion resistance and adjustability resistivity on a large scale and the like, and is easy to process, so that the composite material can be widely applied to the modern electronics industry, information industry and high-tech fields. The composite conductive film disclosed by the invention is simple in process, high in production efficiency and easy in implementation of industrial large-scale production.

The invention belongs to the field of macromolecular composite materials and in particular relates to a wear-resistant hard composite material using a novel nanocarbon material graphene as a filler and a preparation method thereof. The composite material is a hard composite material plate formed by blending and hot-pressing a polymer matrix and the graphene, and is prepared through the following steps: mixing the graphene, the polymer matrix and a rare earth stabilizing agent uniformly; melting and blending by using a torque rheometer to obtain a block-shaped composite; hot-pressing by using a flat vulcanizing machine to obtain the hard composite plate, wherein the composite material comprises 0.1-3wt% of two-dimensional graphene nanocarbon material. The polymer-based composite material using the carbon material as the filler has the characteristics of light weight, easiness in processing, corrosion resistance, friction resistance and the like, and is widely applied in the fields of national defense industry and automobiles. The composite material can meet the increasingly higher tribological performance requirements of the fields of aviation, aerospace, automobiles, machinery and the like on the existing high-performance polymer composite materials; the preparation process of the composite material is simple; industrial production is realized easily.

The invention belongs to the field of recovery and utilization of tungsten secondary resources, and is a method for recovering tungsten and tin metal from APT waste, which is characterized in that the process includes: APT waste is pre-enriched by a shaking table, and a large amount of mud and sand is discarded; The magnetic separator separates a large amount of magnetic substances, and after the sulfide ore is preferentially flotation, it is further refined by a groove shaker, and finally the tungsten and tin metals are separated by flotation, and the tungsten concentrate and tin concentrate are selected. The invention has the advantages of easy control of process conditions, strong operability, simple process, low production cost, waste water can be recycled, zero discharge of waste water is realized, and environmental pollution is avoided. It is easy to realize industrial scale production, and it is a technology for reducing, harmless and recycling APT waste; it has significant economic, social and ecological benefits.

The invention relates to a making method of a graphene oxide-containing antibiosis and mildew prevention wallpaper, and the antibiosis and mildew prevention wallpaper obtained through the method. The method is characterized in that an antibiosis and mildew prevention agent prepared in the invention is uniformly distributed on a base paper through a sprinkling technology to obtain the antibiosis and mildew prevention wallpaper. Synergism of nanometer graphene oxide, Purpleflower Crotalarla Herb extract and nanometer cerium oxide makes the antibiosis, mildew prevention and peculiar smell removal effects of the wallpaper are substantially improved, the mildew prevention grade is 0 grade, the antibiosis rate to Staphylococcus aureus and Escherichia coli reaches up to 99.9%, and the antibiosis rate to moulds is 100%. The wallpaper does not contain formaldehyde or other toxic substances, so the formaldehyde adsorption effect can reach 98%, improvement of household environment is facilitated, physical and mental pleasant feeling is brought for users, and the use values and the economic benefit of the wallpaper are improved.

The invention relates to a multistage stretching technology for manufacture aramid fiber III, which belongs to the technical field of chemical fiber. The multistage stretching technology comprises a negative stretching technology, plasticizing stretching treatment, water washing and plasticizing stretching treatment again to obtain final products. The multistage stretching technology can obviously improve the mechanical property of aramid fiber III, the multifilament stretching strength is increased to 32cN / dtex from 30cN / dtex, and the stretching modulus is increased to 950cN / dtex from 850cN / dtex. High-strength and high-modulus fiber obtained can be applied to applicable fields with higher market requirements.

The invention belongs to the technical field of preparation of an electronic reagent and relates to a device and a method for preparing electronic ethylene carbonate by coupling crystallization with rectification. The device for preparing electronic ethylene carbonate by coupling crystallization with rectification provided by the invention comprises a raw material storage tank, a falling film crystallizer, a rectifying column, a first product tank, a transition tank and a second product tank, wherein the raw material storage tank is connected with a feeding port of the falling film crystallizer; a discharging head pipe is arranged at a discharging port of the falling film crystallizer; the discharging head pipe is respectively connected with the feeding port of the falling film crystallizer, the first product tank and the transition tank; the transition tank is connected with the rectifying column; an outlet at the top of the rectifying column is connected with the second product tank; the outlet at the bottom of the rectifying column is connected with the raw material storage tank. According to the invention, the two technologies of falling film crystallization and rectification are coupled with each other, the deficiencies thereof are mutually made up, more efficient separating operation is realized, the prepared ethylene carbonate can reach ultra-clean high-purity electronic level, and meanwhile, the structure is simple, the operation is convenient, the energy consumption is low and the cost is low.

The invention relates to a comprehensive utilization method of electrolytic manganese residue washing liquid. The comprehensive utilization method comprises the following steps: (1) purifying, namelyadding a heavy metal precipitator and activated carbon into electrolytic manganese residue washing liquid, stirring for reaction, and filtering; (2) carrying out manganese precipitation, namely addingammonium hydrogen carbonate to precipitate manganese into manganese carbonate, and carrying out pressure filtering washing and drying, so as to obtain crude manganese carbonate; (3) carrying out deamination, namely adding lime into the manganese precipitation residual liquid to generate precipitation and deamination reaction, carrying out solid-liquid separation, adjusting the pH value of solids,carrying out pressure filtering drying to obtain putty powder, pumping filtrate into a deamination tower, carrying out deamination, adjusting the pH value of solution with carbon dioxide, and reusingthe solution for washing residue; and (4) carrying out carbonization, namely reacting by virtue of ammonia gas exhausted from the deamination tower and carbon dioxide, so as to generate ammonium hydrogen carbonate. By virtue of a circulating production process, a manganese carbonate product is obtained, meanwhile, two products including ammonium hydrogen carbonate and a gypsum-base internal wallputty raw material can be further produced, and soluble substances in the manganese residue are adequately recycled and comprehensively utilized, so that the treatment cost is greatly lowered, and thecomprehensive utilization method has good economic benefits.

The invention relates to a method for preparing a metal matrix composite, in particular to a method for preparing a particle-enhanced metal matrix composite by laminating technology. In the method, a metal matrix in the metastable state such as a fine-grained, even amorphous state and the like obtained by combining quick cooling technology and the enhancement of ceramic particles is combined with the ceramic particles to achieve higher material performance; molten metal is blown onto surfaces of the ceramic particles under the protection of inert gases, and the ceramic particles are combined with the matrix firmly by rolling compaction; the molten metal blown later is compounded with a metal layer blown earlier, so that the combination of the ceramic particles and the metal matrix during the rolling compaction is improved further; and the processes are performed repeatedly until the particle-enhanced metal matrix composite with specified thickness is obtained. The method is easy and convenient to operate, and the large-scale industrial production is easy to realize; and due to high cooling rate, the matrix metal has high performance, and an interface reaction between the particles and the metal matrix is relieved simultaneously.

The invention discloses an acetylcysteine gargle for treating dental ulcers, and a preparation method thereof. The preparation method comprises the following steps: cooling a small amount of purified water by mass percent; adding the acetylcysteine and then stirring and mixing; under a stirring action, regulating the pH value until the acetylcysteine is dissolved; adding a solution stabilizer, a corrigent and a corrosion remover and mixing; adding poloxamer and then stirring till dissolving; statically placing an obtained mixture; filtering the mixture; and adding the water to a filtrate, thereby obtaining the acetylcysteine gargle. The acetylcysteine gargle prepared by using the method has the functions of quickly relieving pain and preventing / treating the ulcers, and especially has the medicinal efficacy of inhibiting the continuous ulcer expansion and promoting the ulcer wound healing for patients accepting radiotherapy, chemotherapy and bone marrow transplantation. The method provided by the invention has the advantages of simple preparation process and easiness in industrial scale production realization. The acetylcysteine gargle provided by the invention has the advantages of high stability, single and clear active ingredients and good quality controllability, thereby enriching the drug category for adjuvant therapy of clinical cancer. Therefore, a good selection for the nursing service of the patients accepting the radiotherapy is provided.

The invention discloses edible ink for ink-jet printing on the surface of chocolate, which comprises the following components in percentage by weight: 0.01-40% of natural edible pigment, 0.1-50% of emulsifier and the balance of water. The preparation method comprises the following steps: continuously stirring 0.1-50wt% of emulsifier and the water at 35-120 DEG C until the both are completely dissolved and homogenized to form liquid emulsifier; adding 0.01-40wt% of natural edible pigment into the liquid emulsifier, and continuously stirring uniformly to obtain a uniformly mixed solution; and performing reduced pressure filtration on the solution obtained in the previous step with filter paper of which the pore size is 0.5mu m, thus obtaining the product. Compared with the prior art, the ink disclosed by the invention is safe to eat and highly applicable to various ink-jet printers, and has the advantages of excellent wettability and affinity, high stability, high quality and durability and the like for chocolate.

The invention relates to a residual oil hydrogenation catalyst and a preparation method thereof; 1) a mixed body of alumina and activated carbon is used as a carrier, the weight of activated carbon in the carrier accounts for 5-35%, and the weight of alumina accounts for 65-95%; 2) the activity of the catalyst is Component content is based on the total weight of the catalyst as 100%, Ni 2 P is 1~14%, MoO 3 and / or WO 3 3-8%, and / or CoO and / or NiO 1-5%, the rest is carrier; 3) Pore volume is 0.3-1.0ml / g; 4) Specific surface is 50-280m 2 / g; A small amount of activated carbon was introduced into the alumina to reduce the Ni 2 The reaction of P active component with alumina during the formation process improves its dispersibility and makes full use of Ni 2 The high activity of P and the carrier advantages of alumina-activated carbon kneading body can further improve the catalyst's ability to desulfurize, carbon residue and other impurities.

The invention belongs to the technical field of functional materials, relates to the preparation of aerogel, and particularly relates to a preparation method of graphene aerogel powder and the graphene aerogel powder. The preparation method of the graphene aerogel powder comprises the following steps: firstly freezing graphene-based slurry or dispersion liquid, thus obtaining a frozen sample; thencrushing and screening the frozen sample at a low temperature, thus obtaining iced particles; and freeze drying the iced particles, thus obtaining the graphene aerogel powder. By virtue of the method, the explosion danger in the process of crushing the graphene oxide aerogel can be avoided, the drying speed in the freeze drying process can be increased, and the preparation method has the advantages of simplicity, safety and easiness in amplification.

The invention discloses edible ink for ink-jet printing on the surface of an eggshell, which comprises the following components in percentage by weight: 3-6% of edible pigment, 0.01-0.5% of hydroxypropyl cellulose, 0-20% of propanediol, 0.0001-0.1% of ink lubricant, 0.0001-0.05% of dispersant and the balance of water. The preparation method comprises the following steps: preparing 0.1-5wt% of hydroxypropyl cellulose water solution; preparing the ink lubricant having a polydimethylsiloxane-silicon dioxide ratio of (8.5:1.5)-(9:1); preparing an emulsion from the ink lubricant, the dispersant and the water; and preparing the product from the edible pigment, the propanediol, the hydroxypropyl cellulose water solution and the emulsion. Compared with the prior art, the ink disclosed by the invention is safe to eat and highly applicable to various ink-jet printers, and has the advantages of excellent visibility, water resistance, stability and the like for an eggshell.

The invention discloses a preparation method for a high heat-resistant and high-strength polylactic acid fiber. The preparation method comprises the following steps: introducing an organic small molecule nucleating agent to polylactic acid through melt mixing; then self-assembling molecules of the organic small molecule nucleating agent having the content of 0.05 to 0.5wt% to form slender and efficient nucleating microfiber highly oriented along a fiber drawing direction under the actions of a melt spinning temperature field and a shear force field, wherein the microfiber induces the polylactic acid to be crystallized to form a highly oriented crystal structure while the crystallization of the polylactic aid is remarkably accelerated, so that the finally obtained high-performance polylactic acid fiber has the crystallinity degree of 42 to 59%, the tensile strength of 400 to 690 MPa and the boiling water shrinkage of 0.65 to 4.63%. The preparation method disclosed by the invention is not only smart in concept, and simple and efficient in process, easily realizes industrial scale production and opens up a simple and effective approach for development of the high heat-resistant and high-strength polylactic acid fiber.

The invention relates to hydrochloric acid acotiamide tablets and a preparation method thereof. The tablets are prepared from, by weight, 20-60 parts of hydrochloric acid trihydrate, 40-80 parts of a filling agent, 2-20 parts of a disintegrating agent, 1-8 parts of a binding agent and 0.5-6 parts of a lubricating agent. According to the hydrochloric acid acotiamide tablets and the preparation method thereof, by increasing the silicon dioxide using amount within a reasonable range, the indissolvable hydrochloric acid trihydrate in a 0.01-N hydrochloric acid medium can be better dissolved, the bioavailability and the stability of the hydrochloric acid trihydrate are improved, and overdependence on a raw material preparation technology is reduced. In addition, a formula and a preparation technology of the hydrochloric acid acotiamide tablets are simple and easy to operate, the production cost is saved, and the preparation product quality and the treatment effect are improved.

The invention discloses a PVDF antibacterial film doped with nano-zinc oxide and a preparation method. The film is prepared by certain parts, by weight, of nano-zinc oxide, pore-foaming agent, organic solvent and PVDF, the steps are that (1) the weighed pore-foaming agent and nano-zinc oxide are added to the organic solvent for ultrasonic dispersion; (2) the weighed PVDF is added to the organic solvent, and the mixture is heated, stirred, stood and defoamed to obtain a casting film liquid; (3) after the casting film liquid is scrapped into a film, the film is placed into a solidification liquid and soaked until the film falls, and the PVDF antibacterial film doped with the nano-zinc oxide is obtained. The formula is reasonable, the use is convenient, the antibacterial rate of the PVDF antibacterial film doped with the nano-zinc oxide can be improved by more than 60%, the film contamination index is reduced by 80%, and the microbial contamination resistance of the film is remarkably enhanced. The water flux is improved by more than 100%, and the hydrophilia is improved remarkably.

The invention belongs to the toughening and modifying field of polymer composite materials, in particular relates to a method for toughening and modifying a rigid polyvinyl chloride composite material and aims at obtaining a graphene / polyvinyl chloride composite material and solving the performance defect of poor toughness of the rigid polyvinyl chloride material. A graphene carbon nanomaterial is evenly dispersed in a polyvinyl chloride matrix, a soft lamellar structure of the graphene capable of curling and bending in the polyvinyl chloride matrix serves as an elastic particle phase so as to play a role of toughening and modifying the polyvinyl chloride. Polyvinyl chloride powder, a stabilizer, a modifier acrylate and the graphene carbon nanomaterial are premixed in a high-speed stirrer to obtain the graphene / polyvinyl chloride composite material by using a process of melt bending through a torque rheometer and a two-roll mill and a process of hot pressing molding through a flat vulcanizing machine. According to the method for toughening and modifying rigid polyvinyl chloride, the soft and curly graphene layer plays a role of elastic particle in the polyvinyl chloride, so that the breaking elongation and the notch impact strength of the polyvinyl chloride can be obviously improved.

The invention discloses an edible water-based ink and a preparation method of the edible water-based ink. The edible water-based ink comprises the following ingredients: 60-85% of mineral water, 2-8% of sucrose, 2-6% of a pigment, 2-8% of a thickener, 2-10% of table salt and 5-20% of an adjuvant. The preparation method of the edible water-based ink comprises the steps of a) weighing the ingredients in percent by weight as above; b) placing the mineral water in a food mixing machine, adding the thickener and the adjuvant under stirring, and keeping on stirring to obtain a colloidal solution; c) sequentially adding sucrose, table salt and the pigment in the colloidal solution, and obtaining a mixed solution after stirring; and d) grinding the mixed solution by a three-roll grinder, and conducting filter pressing after grinding, wherein the filtrate is the edible water-based ink. The edible water-based ink has safe and edible formula ingredients and is simple in preparation method, excellent in operability, low in cost and investment and very easy for industrialized mass production.

The invention discloses an olaquindox slow release particle and a preparing method and application thereof. The olaquindox slow release particle is prepared by an olaquindox raw material, a dispersing agent and a release retardant. The preparing method includes the steps of weighing the dispersing agent according to formula proportion, and heating and fusing the dispersing agent to be evenly mixed; adding olaquindox to be evenly stirred; adding the release retardant to be evenly stirred; and conducting fluidized-bed spray granulation nodulizing, cooling, screening and collecting through a scientific process. By means of the olaquindox slow release particle, absorption of olaquindox in the intestinal tract of a target animal can be reduced, the bioavailability of the olaquindox is reduced by about 10%-50%; after the animal eats the olaquindox slow release particle, the olaquindox slow release particle can be released in the intestinal tract in the whole process, and the action concentration and the action time of the olaquindox in the intestinal tract are prolonged. According to the preparing method, in the production process, dust and static electricity are not generated, and cross contamination of feed production is effectively avoided; the slow release particle is good in mobility and dispersibility, feed and drugs can be conveniently mixed, and drug application is convenient.

The invention discloses a method for synthesizing silyl-terminated polyether. The method comprises the following steps of: performing addition polymerization on alkylene oxide to an initial compound having reactive oxygen atoms by a double metal cyanide catalysis method to obtain multi-terminated polyether with the molecular weight of 1,000 to 50,000, wherein the end groups of the multi-terminated polyether are the oxygen atoms which are connected with DMC catalytic reactive groups by complexation; and removing the alkylene oxide which reacts insufficiently, adding silane with epoxy groups, performing ring-opening addition reaction on the epoxy groups under the action of the DMC catalytic reactive groups to connect the silane to the oxygen atoms at the tail ends of the polyether, and purifying to obtain the silyl-terminated polyether. On the premise of not using an isocyanate compound, the silyl-terminated polyether is obtained by two steps of reactions by the method; and the method for synthesizing the silyl-terminated polyether has the advantages of simple steps, smooth synthesis process, accordance with the requirement of environmental protection, and easy realization of industrial mass production.

The invention discloses a preparing method for high-purity manganese sulfate. The preparing method includes the steps that manganese sulfate monohydrate obtained through high-temperature crystallization is put into a rotary kiln and is burned with methyl alcohol, hydroxyl ions discharged after temperature increment and a burning value are mixed into powder-crystal-shaped manganese sulfate, and magnesium ions, potassium ions and sodium ions are caught and then are coked; the dried and coked magnesium-potassium-sodium mixture is put into a dissolution kettle, deionized water is added, dissolution and filtering are carried out, and un-dissolved substances (coked magnesium-potassium-sodium granules) are separated out; a qualified manganese sulfate solution is sent to a secondary high-temperature crystallizer and crystallized, a manganese sulfate hydrated crystal is obtained, then the product is sent and dried, and the qualified manganese sulfate is obtained. The preparing method is simplein step and easy to operate, the temperature and the pH value are not required to be strictly controlled, a large quantity of high-purity impunity removing medicaments are also not required to be consumed, and through the coking effect and different dissolution degrees of all impurities, the impurities are filtered out and removed out, the impunity removing effect is remarkable, secondary pollution on the environment can be avoided, the production cost is low, and industrialization scale production is easy to achieve.

The invention relates to hot working process of a high-strength deformation magnesium alloy. The method comprises selecting appropriate thermal treatment temperature and time, controlling processes of dissolving of compound phases, exsolution, precipitation and the like, on the basis of stability of different compound phases and different characteristics of thermodynamics and kinetics in magnesium alloys, therefore effectively controlling the histological structure of the alloy for making that the magnesium alloy both have excellent plastic property and obtain high strength. According to the invention, a hot working system is formulated according to the character of magnesium alloy compounds and the system having a wide applicability is prone to realize industrialization scale production, is suitable for magnesium-zincium base aging strengthening type magnesium alloy and is especially suitable for ZK system high-strength deformation magnesium alloy with the zincium bigger than or equal to 6.0.

The invention discloses a method for separating nucleotides through ion exchange resin composite chromatography. The method is characterized by comprising the following steps: selecting resins with excellent ion exchange separation effects from multiple kinds of similar anion exchange resins by adopting a batch exchange adsorption rate, wherein the resins are used for chromatographic separation ofcation and anion exchange resin combination; performing gradient elution under neutral or weakly-alkaline conditions (pH of 7-10) by adopting a NaCl aqueous solution, thereby obtaining four single nucleotides. Compared with the prior art, the method disclosed by the invention has an excellent separation effect and high nucleotide adsorption capacity, the resin separation yield can reach 92.5%, acarbon column enrichment method can be saved, crystals can be obtained by direct concentration even without concentrating, the cost is greatly reduced, large-scale industrial production of four high-concentration single nucleotides is easily realized, the cost is low, energy conservation and emission reduction are realized, and the green manufacturing environmental protection concept is met.

The invention relates to an apixaban pellet and a preparation method thereof. The apixaban pellet is composed of, from interior to exterior, a blank pellet core, a drug-containing layer and a coating layer, wherein the drug-containing layer is composed of micronized apixaban, a binder and a disintegrating agent. The apixaban pellet comprises, by weight, 60 to 84 parts of the blank pellet core, 2 to 7 parts of the micronized apixaban, 3 to 10 parts of the binder, 5 to 20 parts of the disintegrating agent and 2 to 8 parts of the coating layer. Thus, the apixaban pellet obtained in the invention has a rough and regular shape and uniform particle size; and compared with commercially available tablets, the apixaban pellet provided by the invention has better stability, faster dissolving-out rate and higher bioavailability.